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Search results for: Augustów Forest
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Changes in oxidative stress in the rat brain during post-cardiac arrest reperfusion, and the effect of treatment with the free radical scavenger idebenone
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DNA-damaging imidazoacridinone C-1311 induces autophagy followed by irreversible growth arrest and senescence in human lung cancer cells
PublicationImidazoacridinone 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor inhibitor of topoisomerase II and FMS-like tyrosine kinase 3 receptor. In this study, we describe the unique sequence of cellular responses to C-1311 in human non-small cell lung cancer (NSCLC) cell lines, A549 and H460. In A549 cells, C-1311 (IC80 = 0.08 µM) induced G1 and G2/M arrests, whereas H460 cells (IC80 = 0.051 µM) accumulated...
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A Dynamic Forecast Demand Scenario Analysis to Design an Automated Parcel Lockers Network in Pamplona (Spain) Using a Simulation-Optimization Model
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Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
PublicationG-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 motifs form in vivo and are implicated in regulation of such processes as gene expression and chromosome maintenance. The structure and stability of various G4 topologies were determined experimentally; however, the driving forces for their formation are not fully...
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Why do G-quadruplexes dimerize through the 5’-ends? Driving forces for G4 DNA dimerization examined in atomic detail
PublicationG-quadruplexes (G4) are secondary structures formed by guanine-rich nucleic acid sequences and shown to exist in living cells where they participate in regulation of gene expression and chromosome maintenance. G-quadruplexes with solvent-exposed guanine tetrads show the tendency to associate together through cofacial stacking, which may be important for packaging of G4-forming sequences and allows for the design of higher-order...
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Beyond the helium buffer: 12C−2 rotational cooling in cold traps with H2 as a partner gas: interaction forces and quantum dynamics
Publicationabstract = { The scattering cross-sections and corresponding rate coefficients for rotationally inelastic collisions of $^{12}$C$_2$^-$ ($^2 \Sigma_g^+$) with H$_2$ ($^1 \Sigma_g^+$) are presented over a broad range of cold-trap temperatures. They have been calculated using quantum scattering theory that employs a new ab initio potential energy surface. The rate coefficients for the inelastic processes in the anionic partner are...
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The influence of rotor-stator axial gap on the aerodynamic forces generatedin the shroud clearance of a turbine stage. Part I: Pressure field
PublicationPrzedstawiono wyniki badań doświadczalnych wpływu zmiany luzu osiowego na rozkład ciśnienia w uszczelnieniu nadbandażowym stopnia powietrznej turbiny modelowej. Wykazano, że w przypadku uszczelnienia promieniowego zmiana luzu osiowego nieznacznie zmienia rozkład ciśnienia w szczelinie nadbandażowej w porównaniu ze zmianą mimośrodowości czy skośnego ustawienia osi wirnika względem osi korpusu.
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Increased susceptibility of PARP-1 KO cells to antitumor triazoloacridone C-1305 is associated with permanent G2 cell cycle arrest.
PublicationTriazoloakrydon C-1305 jest nowym inhibitorem topoizomerazy II wykazującym wysoką aktywność przeciwnowotworową. W tej pracy badaliśmy działanie cytotoksyczne pochodnej C-1305 i jej analogu strukturalnego C-1533 wobec komórek fibroblastów mysich i dwóch mutantów, w których uszkodzono gen PARP-1. Jak wykazaliśmy, komórki z uszkodzonym genem PARP-1 są nadwrażliwe na działanie związku C-1305 w porównaniu z komórkami PARP-1 +/+ podczas...
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Closed forms of the Green's function and the generalized Green's function for the Helmholtz operator on the N-dimensional unit sphere
PublicationPokazano, że funkcję Greena dla operatora Helmholtza na N-wymiarowej sferze jednostkowej można wyrazić przez funcję Gegenbauera pierwszego rodzaju. W tych przypadkach, w których funkcja Greena nie istnieje, skonstruowano uogólnioną funkcję Greena.
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The effect of a polyharmonic structure of the perturbation signal on the results of harmonic analysis of the current of a first-order electrode reaction
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Early Predictors of Learning a Foreign Language in Pre-school – Polish as a First Language, English as a Foreign Language
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Concentrations of alfa- and gamma- tocopherols in human breast milk during the first months of lactation and in infant formulas
PublicationThe aim of this study was to determine the concentrations of alpha- and gamma-tocopherols in human breast milk samples from different periods of lactation and to compare them with tocopherol content in commercially available formulas for infants at corresponding ages. The study included 93 breast milk samples obtained on the 2nd (colostrum, n=17), 14th (n=30), 30th (n=27) and 90th day of lactation (n=19), along with 90 samples...
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Microscopic 75^As NMR study of the effect of impurities on the first-order spin-density-wave transition in BaFe2As2
PublicationOpisane są wyniki badań NMR na 75^As w monokryształach i próbkach polikrystalicznych BaFe2As2. Zanieczyszczenia cyną wpływają na niskoenergetyczne fluktuacje spinowe i obniżają temperaturę krytyczną ze 138K do 85K.
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Laboratory Examination of Frost-heaving Properties of Road Unbound Mixtures Based on Fines Content and Plasticity Index
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Positive solutions to second-order differential equations with dependence on the first-order derivative and nonlocal boundary conditions
PublicationIn this paper, we consider the existence of positive solutions for second-order differential equations with deviating arguments and nonlocal boundary conditions. By the fixed point theorem due to Avery and Peterson, we provide sufficient conditions under which such boundary value problems have at least three positive solutions. We discuss our problem both for delayed and advanced arguments α and also in the case when α(t)=t, t∈[0,1]....
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Examination of cyp51A and cyp51B expression level of the first Polish azole resistant clinical Aspergillus fumigatus isolate
PublicationAspergillus fumigatus is one of the most prevalent airborne fungal pathogens causing infections worldwide. Most A. fumigatus strains are susceptible to azoles, which are administered as the first line therapeutics. However, during last decade the acquired resistance to triazoles by these species has been described. There is a number of publications concerning the examination of clinical A. fumigatus strains from different countries,...
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Renal Regulation of Potassium Homeostasis in Calves in the First Week of Life Including the Role of Atrial Natriuretic Peptide
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Novel approach to ecotoxicological risk assessment of sediments cores around the shipwreck by the use of self-organizing maps
PublicationMarine and coastal pollution plays an increasingly important role due to recent severe accidents which drew attention to the consequences of oil spills causing widespread devastation of marine ecosystems. All these problems cannot be solved without conducting environmental studies in the area of possible oil spill and performing chemometric evaluation of the data obtained looking for similar patterns among pollutants and optimize...
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First evaluation of wastewater discharge influence on marine water contamination in the vicinity of Arctowski Station (Maritime Antarctica)
PublicationIn Antarctica,waste is generatedmainly during scientific research programmes and related logistics. In this study, the impact ofwastewater on the western shore of Admiralty Baywas investigated during austral summer in 2017 and 2019. A range of physicochemical parameters and the presence of selected trace metals, formaldehyde and different groups of surfactants were determined in wastewater coming from Arctowski Station and in nearby coastal...
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Light formed through urban morphology and different organism groups: First findings from a systematic review
PublicationThe prevailing implementation and usage of contemporary lighting technologies and design practices in cities have created over-illuminated built environments. Recent studies indicate that exposure to electric lighting effects formed through spatial characteristics has visual, physiological, and behavioural effects on both humans and non-humans, such as wildlife. In order to gain a better understanding of the impact that electric...
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Sustainable bioethanol production from first- and second-generation sugar-based feedstocks: Advanced bibliometric analysis
PublicationBioethanol is produced from carbohydrate-containing feedstocks through fermentation. Based on a bibliometric review of studies published between 2012 and 2021, we analyzed those on sustainable bioethanol production. The Web of Science main collection yielded 1647 publications, which were analyzed using VOSViewer, CiteSpace, and ArcMap software. More than half of these publications originated from some Asian countries, corresponding to...
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Molecular transformation of dissolved organic matter in manganese ore-mediated constructed wetlands for fresh leachate treatment
PublicationThe organic matter (OM) and nitrogen in Fresh leachate (FL) from waste compression sites pose environmental and health risks. Even though the constructed wetland (CW) can efficiently remove these pollutants, the molecular-level transformations of dissolved OM (DOM) in FL remain uncertain. This study reports the molecular dynamics of DOM and nitrogen removal during FL treatment in CWs. Two lab-scale vertical-flow CW systems were...
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Bilateral power supply of the traction network as a first stage of Smart Grid technology implementation in electric traction
PublicationSince 2001, trolleybus system in Gdynia has been involved in many activities related to the reduction of power consumption, both in terms of implementation and research and development. In PKT, in cooperation with SESTO company, started applications of Smart Grid technologies in supply network: the bilateral supply. The paper presents results of this this novel investment.
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Bending and buckling formulation of graphene sheets based on nonlocal simple first-order shear deformation theory
PublicationThis paper presents a formulation based on simple first-order shear deformation theory (S-FSDT) for large deflection and buckling of orthotropic single-layered graphene sheets (SLGSs). The S-FSDT has many advantages compared to the classical plate theory (CPT) and conventional FSDT such as needless of shear correction factor, containing less number of unknowns than the existing FSDT and strong similarities with the CPT. Governing...
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Structural Model of the Bilitranslocase Transmembrane Domain Supported by NMR and FRET Data
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Implementacja wykrywalnych usług typu REST na platformie Jakarta EE
PublicationNiniejszy rozdział przedstawia propozycję w jaki sposób może być realizowana implementacja wykrywalnych usług sieciowych opartych na stylu architektonicznym REST na platformie Jakarta EE. Zostały tutaj przedstawione zarówno podstawy teoretyczne niezależne od zastosowanej platformy technologicznej, jak i szczegóły implementacji w technologii JAX-RS wchodzącej w skład platformy Jakarta EE. W szczególności zostały tutaj przedstawione...
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Antrakofilne gatunki Macromycetes w Lasach Oliwskich (Trójmiejski Park Krajobrazowy) = Anthracophilous species of Macromycetes in the Oliwskie Foresrs (Trójmiejski Ladscape Park)
PublicationW Lasach Oliwskich (Północna Polska), w miejscach wypalania drewna stwierdzono kilka gatunków macromycetes zaliczanych do grzybów antrakofilnych, np. Lyophyllum antracophilum, Faerberia carbonaria, Geopyxis carbonaria i in. Sprządzono krótką charakterystykę tych taksonów, podano położenie ich stanowisk.
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The influence of feed rate and shear forces on the devulcanization process of ground tire rubber (GTR) conducted in a co-rotating twin screw extruder
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The influence of feed rate and shear forces on the devulcanization process of ground tire rubber (GTR) conducted in a co-rotating twin screw extruder
PublicationThe search for new ways to recycling of rubber waste has been the aim of many studies conducted by research centers and companiesworldwide. The results of our investigations on the process of continuous thermomechanical devulcanization of ground tire rubber using a twin screw extruder are presented.We used a co-rotating twin screw extruder with a special configuration of plasticizing unit, enabling generation of considerable shear...
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Prezentacja dwóch prac fotograficznych z cyklu "Ubrania" na wystawie zbiorowej "Wideoopukiwanie".Format prac 75 x 50 cm.
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Revitalisation Living Lab as a Format to Accelerate an Energy Transition in Polish Rural Areas: The Case Studies of Metropolitan Outskirts Gdańsk-Orunia and Lubań
PublicationThe paper deals with the issue of energy transition in the revitalization process dedicated to the rural and semi-rural areas of the Pomerania Region (PR). Two distinct areas, located in sub- and ex-urban zones of the Gdańsk-Gdynia-Sopot Metropolitan Area (OMGGS), in which bottom-up community initiatives have been playing a key role in the transformation, have been focused on. The village of Lubań (Municipality of Nowa Karczma)...
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3D calculations of aerodynamic forces causing self-excited vibrations of turbine rotor systems. Part I: Shroud seal flow inwestigations
PublicationOpisano numeryczną i doświadczalną metodę badania przepływu w uszczelnieniu nadbandażowym stopnia turbinowego. Badania numeryczne przeprowadzono programem Fluent, a badania doświadczalne wykonano na powietrznej turbinie modelowej. Uwzględniono niesymetryczny rozkład szczeliny nadbandażowej na skuteknie centrycznego położenia osi wirnika względem osi cylindra. Zamieszczono przykładowe wyniki.
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The Effect of Freezing Sheep’s Milk on the Meltability, Texture, Melting and Fat Crystallization Profiles of Fresh Pasta Filata Cheese
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Tri(mesityloxy)silanethiol – The First Structurally Characterized Organoxysilanethiol (Contributions to the Chemistry of Silicon–Sulfur Compounds. 77 [1])
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Analytical Buckling of FG Nanobeams on The Basis of A New One Variable First-Order Shear Deformation Beam Theory
PublicationIn this work, buckling analysis of functionally graded (FG) nanobeams based on a new refined beam theory has been analyzed. The beam is modeled as an elastic beam subjected to unidirectional compressive loads. To achieve this aim, the new obtained beam theory has only one variable which leads to one equation similar to the Euler beam theory and also is free of any shear correction factor. The equilibrium equation has been...
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Analytical Buckling of FG Nanobeams on The Basis of A New One Variable First-Order Shear Deformation Beam Theory
PublicationIn this work, buckling analysis of functionally graded (FG) nanobeams based on a new refined beam theory has been analyzed. The beam is modeled as an elastic beam subjected to unidirectional compressive loads. To achieve this aim, the new obtained beam theory has only one variable which lead to one equation similar to Euler beam theory and also is free of any shear correction factor. The...
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260. The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early brest cancer
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Water Needs of Black Locust Robinia pseudoacacia L. in the First Three Years of Growing in the Reclamation Plantings in Poland
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Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
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The possibilities of utilization of bottom sediments from fresh water fish farms on the base of legal status of biosludge utilization'
PublicationHodowle ryb łososiowatych są źródłem stosunkowo niewielkich ilości odpadów, jakim są osady denne, ale które stanowią istotny problem do rozwiązania dla eksploatatora obiektu. Przepisy prawne generalnie pomijają ten aspekt gospodarki odpadami. właściciele stawów hodowlanych radzą sobie z tymi osadami lepiej lub gorzej, ale przeważnie ich działania ukierunkowane są na tzw. przyrodnicze ich wykorzystanie - najczęściej w granicach...
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The antioxidative properties of white cabbage (Brassica oleracea var. capitata f. alba) fresh and submitted to culinary processing
PublicationKapusta biała stanowi jeden z podstawowych składników diety w Europie centralnej. W publikacji autorzy skupili się na określeniu właściwościach przeciwutleniających kapusty świeżej, kiszonej i poddanej obróbce termicznej. Te właściwości zostały oszacowane dla soków przy wykorzystaniu systemów pozakomórkowych, w komórkach HT29 pod kątem ochrony przed utlenieniem DNA oraz poprzez symulację GSTs i naprawę DNA. Wszystkie badane soki...
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A targeted mass spectrometry immunoassay to quantify osteopontin in fresh-frozen breast tumors and adjacent normal breast tissues
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Using Statistical Methods to Estimate The Worst Case Response Time of Network Software Running on Indeterministic Hardware Platforms
PublicationIn this paper we investigate whether the statistical Worst Case Execution Time (WCET) estimation methods devised for embedded platforms can be successfully applied to find the Worst Case Response Time (WCRT) of a network application running on a complex hardware platform such as a contemporary commercial off-the-shelf (COTS) system. Establishing easy-to-use timing validation techniques is crucial for real-time applications and...
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Comparative molecular dynamics study of dimeric and monomeric forms of HIV-1 protease in ligand bound and unbound state
PublicationHuman immunodeficiency virus type 1 protease (HIV-1 PR) is a viral-encoded enzyme that forms a homodimer. HIV-1 PR is essential for replication and assembly of the virus and inactivation of HIV-1 PR enzyme causes production of immature, noninfectious viral particles and thus HIV-1 PR is an attractive target in anti-AIDS drug design. In our current work, we performed molecular dynamics (MD) calculations (500 ns) for two different...
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An inverse algorithm for contact heat conduction problems with an interfacial heat source based on a first-order thermocouple model
PublicationInverse problems of contact heat conduction with an interfacial heat source are common in various fields of science, engineering and technology. In this study, an algorithm for their solution is developed based on an inverse parametric optimisation method with an impulse response function describing the heat partition and contact heat transfer. A first-order thermocouple model with a time constant parameter is embedded in the impulse...
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Mechanism of Solute and Thermal Characteristics in a Casson Hybrid Nanofluid Based with Ethylene Glycol Influenced by Soret and Dufour Effects
PublicationThis article models a system of partial differential equations (PDEs) for the thermal and solute characteristics under gradients (concentration and temperature) in the magnetohydrodynamic flow of Casson liquid in a Darcy porous medium. The modelled problems are highly non-linear with convective boundary conditions. These problems are solved numerically with a finite element approach under a tolerance of 10−8. A numerical algorithm...
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A first-principles study of electronic and magnetic properties of 4d transition metals doped in Wurtzite GaN for spintronics applications
PublicationWe studied the electronic and magnetic properties of wurtzite GaN (w-GaN) doped with different concentrations of the 4d transition metal ions Nb, Mo, and Ru. We incorporated spin-polarized plane-wave density functional theory within an ultrasoft pseudopotential formalism. The 4d transition metals were doped at different geometrical sites to determine the geometry with the lowest total energy and the one that induced the largest...
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Suppressors of lapC mutation identify new regulators of LpxC, which mediates the first committed step in lipopolysaccharide biosynthesis
PublicationGram-negative bacteria, such as Escherichia coli, are characterized by an asymmetric outer membrane (OM) with lipopolysaccharide (LPS) located in the outer leaflet and phospholipids facing the inner leaflet. E. coli recruits LPS assembly proteins LapB, LapC and LapD in concert with FtsH protease to ensure a balanced biosynthesis of LPS and phospholipids. We recently reported that bacteria either lacking the periplasmic domain of...
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Magnetizability of the relativistic hydrogen-like atom: applicayion of the Sturmian expansion of the first-order Dirac-Coulomb Green function
PublicationStosując rozwinięcie sturmowskie funkcji Greena-Diraca-Coulomba, znaleziono wyrażenie analityczne dla magnetyzowalności relatywistycznego atomu wodoro-podobnego w stanie podstawowym.
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Structure changes in (Bi-Pb)-Sr-Ca-Cu-O glass ceramics during the first minutes of crystallization.
Publication(Bi0.8Pb0.2)4Sr3Ca3Cu4Ox szkło otrzymano standardową metodą chłodzenia stopionych substratów. Częściowo skrystalizowane próbki otrzymano poprzez wygrzewanie szkła w temperaturze między 700stC i 870stC. Obecność faz krystalicznych badano metodą dyfrakcji rentgenowskiej w temperaturze pokojowej oraz w temperaturze krystalizacji. Stwierdzono obecność faz nadprzewodzących (Bi0.8Pb0.2)2Sr2CuOx, (Bi0.8Pb0.2)2Sr2CaCu2Ox i (Bi0.8Pb0.2)2Sr2Ca2Cu3Ox...