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Search results for: SPLICE VARIANTS
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Survivin splice variants expression in thyroid malignancy
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Evaluation of survivin splice variants in pituitary tumors
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Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria
PublicationIn eukaryotic cells, different organelles interact at membrane contact sites stabilized by tethers. Mitochondrial mitofusin 2 (MFN2) acts as a membrane tether that interacts with an unknown partner on the endoplasmic reticulum (ER). In this work, we identified the MFN2 splice variant ERMIT2 as the ER tethering partner of MFN2. Splicing of MFN2 produced ERMIT2 and ERMIN2, two ER-specific variants. ERMIN2 regulated ER morphology,...
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Expression of alternatively spliced variants of the Dclk1 gene is regulated by psychotropic drugs
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Targeting Spike‐ACE2 Interface of SARS‐CoV‐2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
PublicationThe recent COVID pandemic has shown major impact on public health and economic crisis. Despite the development of many vaccines and drugs against the severe acute respiratory syndrome (SARS) coronavirus 2, the pandemic still persists. The continued spread of the virus is largely driven by the emergence of viral variants such as α, β, γ, delta, epsilon spike, omicron and its subvariants (BA.1,2,3) which can evade the current vaccines...
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New variants of the SDF classifier
PublicationPraca dotyczy problemów związanych z konstruowaniem klasyfikatorów, w których typowa wektorowa reprezentacja obrazu została zastapiona danymi o strukturze macierzowej. W pracy zaproponowano nowe algorytmy oparte na funkcji SDF. Zostały one przetestowane na obrazach przedstawiających cyfry pisane ręcznie oraz na zdjęciach twarzy. Przeprowadzone eksperymenty pozwalają stwierdzić, że wprowadzone modyfikacje istotnie zwiększyły skuteczność...
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Osmotic MD and other membrane distillation variants
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Electron mobility variance in semiconductors: the variance approach
PublicationPraca przedstawia nowe podejście da analizy zjawisk losowych w półprzewodnikach. Uwzględnia kilka mechanizmów zjawisk fluktuacji ruchliwości w półprzewodnikach, prowadzących do powstawamai składowej szumów typu 1/f, dominujących w zakresie małych czetotliwości. Przedstawia analizę sposobu wyznaczenia stałej Hooge'a określającej intensywność szumów typu 1/f.The statistical non-triviality of current carrier mobility fluctuations...
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Common variants of DNA repair genes and malignant melanoma
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Environmental costs for exploitation variants of Racibórz dry polder
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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The presence of prostate cancer at biopsy is predicted by a number of genetic variants
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Poli-optimization of selected variants of steel sandwich panels connections
PublicationPanele kompozytowe odgrywają coraz większą role w różnorodnych zastosowaniach inżynierskich. Jednym z zagadnień kluczowych dla możliwości aplikacyjnych są połączenia między cienkościennymi formami w układzie wzdłużnym i poprzecznym. Praca prezentuje wyniki polioptymalizacji numerycznej wybranych połączeń stalowych paneli typu sandwich.
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The influence of variants of finishing machining on scheduling of shaft components manufacturing
PublicationIn the paper variants of technological processes were presented to the study for piston rods and rams of hydraulic cylinders taking issues into consideration scheduling of course of the production in flexible manufacturing cell. At the carried study an attempt of the estimation of the influence of technological variants on the effectiveness to manufacture the flexible manufacturing system on the basis of preliminary schedules of...
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Efficient bounds on quantum-communication rates via their reduced variants
PublicationWe investigate one-way communication scenarios where Bob operating on his component can transfer some subsystem to the environment. We define reduced versions of quantum-communication rates and, further, prove upper bounds on a one-way quantum secret key, distillable entanglement, and quantum-channel capacity by means of their reduced versions. It is shown that in some cases they drastically improve their estimation.
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Technical and Economic Analysis of the Implementation of Selected Variants of Road Investment
PublicationThe aim of the article is to analyze three variants of modernization and reconstruction of a road intersection, which in practice is the cause of numerous collisions and accidents. Detailed design solutions are presented for them. The aim of the analyses is to indicate an effective solution that, taking into account technical modifications of the road system elements, will ensure the functionality of the road system to the highest...
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Ranking decision variants by subjective paird comparisons in cases with incomplete data.
PublicationMetoda porównań parami wykorzystywana jest do szeregowania skończonej,zwykle niewielkiej liczby wariantów decyzyjnych. W metodzie tej ekspert lub grupa ekspertów proszona jest o wyrażenie swojej opinii dotyczącej każdej pary wariantów w postaci względnej preferenecji jednego wariantu nad drugim.Zdarza się jednak często, że ekspert nie jest w stanie ocenić pary lub par wiariantów i mamy wtedy do czynienia z sytuacją...
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Is mesangial hypercellularity with glomerular immaturity a variant of glomerulosclerosis?
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Spatially variant PSF modeling in confocal macroscopy
PublicationThe point spread function (PSF) of imaging systems plays an essential role in image reconstruction. In the context of confocal microscopy, optical performance degrades towards the edge of the field of view. In confocal macroscopy, the related artifacts are even stronger, as the field of view is much larger. Because the related PSFs are strongly spatially variant, it is essential to be able to model them with few parameters. The...
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Quechers sample preparation method variants for analysis of pesticide residues in fruits and vegetables
PublicationThis article describes the comparison of different versions of an easy, rapid and low-cost sample preparation approach for the determination of pesticide residues in fruits and vegetables by concurrent use of gas and liquid chromatography coupled to MS or ECD for detection. The sample preparation approach is known as QuEChERS, which stands for quick, easy, cheap, effective, rugged and safe. It is a combination of liquid-liquid...
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Ciliary phenotyping in renal epithelial cells in a cranioectodermal dysplasia patient with WDR35 variants
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Variants and Modifications of the Retroauricular Approach Using in Temporomandibular Joint Surgery: A Systematic Review
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Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants
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Comparative analysis of selected design variants of propulsion system for an inland waterways ship
PublicationW pracy zaprezentowano założenia projektowe i wstępną analizę porównawczą dwóch wariantów napędu śródlądowego statku pasażerskiego. Pierwsze rozwiązanie to wariant z przekładnią elektryczną, drugie natomiast, to wariant z przekładnią hydrostatyczną.
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Studies on the influence of technological variants of finishing machining on flow of parts in flexible manufacturing
PublicationIn the article below the problems of influence of variants of finishing processing on flow of machining parts in flexible manufacturing system were presented. The investigations were carried out the technological processes for piston rods and rams of hydraulic cylinders. There were also presented model variants of technological processes for piston rods finished with the burnishing. In these studies the influence of technological...
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Public space as a place of rehabilitation for the elderly – a systematic literature review
PublicationThe phenomenon of the population’s gradual global ageing means that an increasing proportion of research is concerned with the space in which seniors function on a daily basis. They are primarily aimed at identifying elements of the built environment that need updating in the new social context. The purpose of the analyses presented in this article is to review the current scientific literature on various aspects of physical activity...
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On Invariants of Fluid Mechanics Tensors
PublicationThis paper presents physical interpretations of the first and second invariants of tensors of fluid mechanics. Some examples of elementary applications and meanings are also given.
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VARIANT DESIGNING IN the PRELIMINARY SMALL SHIP DESIGN PROCESS
PublicationShip designing is a complex process, as the ship itself is a complex, technical multi-level object which operates in the air/water boundary environment and is exposed to the action of many different external and internal factors resulting from the adopted technical solutions, type of operation, and environmental conditions. A traditional ship design process consists of a series of subsequent multistage iterations, which gradually...
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Novel Tools for Comprehensive Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants
PublicationFamilial hypercholesterolemia (FH) is an autosomal-dominant disorder caused mainly by substitutions in the low-density lipoprotein receptor (LDLR) gene, leading to an increased risk of premature cardiovascular diseases. Tremendous advances in sequencing techniques have resulted in the discovery of more than 3000 variants of the LDLR gene, but not all of them are clinically relevant. Therefore, functional studies of selected variants...
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Association between Age at Diagnosis of Graves' Disease and Variants in Genes Involved in Immune Response
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Drug transporter expression profiling in chemoresistant variants of the A2780 ovarian cancer cell line
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DNA variants in Helicobacter pylori infected patients with chronic gastritis, dysplasia and gastric cancer
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DNA Variants in Helicobacter Pylori Infected Patients with Chronic Gastritis, Dysplasia and Gastric Cancer
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Note on the variance of the sum of gaussian functonals
PublicationDowodzi się oszacowania wariancji sum funkcjonałów losowych, konstruowanych dla zależnego ciągu gaussowskiego.Let (Xi; i = 1; 2; : : :) be a Gaussian sequence with Xi 2 N(0; 1) for each i and suppose its correlation matrix R = (ij)i;j1 is the matrix of some linear operator R : l2 ! l2. Then for fi 2 L 2(), i = 1; 2; : : : ; where is the standard normal distribution, we estimate the variation of the sum of the Gaussian functionals...
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Silica In Silico: A Molecular Dynamics Characterization of the Early Stages of Protein Embedding for Atom Probe Tomography
PublicationA novel procedure for the application of atom probe tomography (APT) to the structural analysis of biological systems, has been recently proposed, whereby the specimen is embedded by a silica matrix and ablated by a pulsed laser source. Such a technique, requires that the silica primer be properly inert and bio-compatible, keeping the native structural features of the system at hand, while condensing into an amorphous, glass-like...
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Evolution-based scheduling of multiple variant and multiple processor programs
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Extracellular Matrix Proteins Expression Profiling in Chemoresistant Variants of the A2780 Ovarian Cancer Cell Line
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P-666 Detecting gene variants correlated with MII oocytes developed during ovarian stimulation
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Comprehensive Comparison of a Few Variants of Cluster Analysis as Data Mining Tool in Supporting Environmental Management
PublicationA few variants of hierarchical cluster analysis (CA) as tool of assessment of multidimensional similarity in environmental dataset are compared. The dataset consisted of analytical results of determination of metals (Na, K, Ca, Sc, Fe, Co, Zn, As, Br, Rb, Mo, Sb, Cs, Ba, La, Ce, Sm, Hf and Th) in ambient air dried and kept alive, by the means of hydroponics, moss baskets collected in 12 locations on the area of Tricity (Poland)....
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passive spice networks from non-passive data
PublicationArtykuł przestawia technike generacji schematow zastepczych w formacie SPICE dla pasywnych układów mikrofalowych. Wynikowy schemat zastepczy ma zagwarantowana pasywnosc. Schematy zastepcze powstaja na podstawie symulacji lub pomiarow w dziedzinie czestotliwosci i moga byc wykorzystane do symulacji w dziedzinie czasu.
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Product Graph Invariants with Applications in the Theory of Information
PublicationThere are a large number of graph invariants. In the paper, we consider some of them, e.g. the independence and chromatic numbers. It is well know that we cannot efficiently calculate these numbers for arbitrary graphs. In the paper we present relations between these invariants and concepts from the theory of information. Concepts such as source coding and transmission over a noisy channel with zero probability of error are modeled...
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Mixed systems with minimal and maximal lifetime variances
PublicationRozważa się mieszane układy złożone ze stałej liczby składników, których czasy zycia są niezależnymi zmiennymi losowymi o jednakowym rozkładzie i dodatniej wariancji. Bada się minimalną i maksymalną wariancję czasu życia rozważanych układów.
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Wybór wariantu outsourcingu informatycznego w praktyce
PublicationW artykule opisano możliwości wykorzystania outsorcingu do obniżenia kosztów eks-ploatacji zasobów informatycznych przedsiębiorstwa. Podano podstawowe informacje związane z eksploatacją zasobów informatycznych. Przedstawiono prace analityczne, które mogą wspomóc wypracowanie podjęcia decyzji o przeniesieniu zasobów informatycznych do outsourcingu. Artykuł opracowano na podstawie rzeczywistego projektu wprowadzonego w przedsiębiorstwie...
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Selection of a manufacturing technology variant for brake master cylinders by DFMA practices
PublicationPrzedstawiono koncepcję zintegrowanego, współbieżnego projektowania konstrukcji oraz procesów wytworzenia i montażu określonej klasy wyrobów tj. pomp hydraulicznych, stosowanych w układach hamulcowych pojazdów dostawczych. Omówiono ograniczenia i możliwości doboru alternatywnych technologii wytworzenia komponentów oraz realizacji procesu montażu, dla określonej postaci konstrukcyjnej wyrobu, a spełniającej wymagania technologiczności...
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Identification, characterization and purification of the lantibiotic staphylococcin T, a natural gallidermin variant
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Some variants of perfect graphs related to the matching number, the vertex cover and the weakly connected domination number
PublicationGiven two types of graph theoretical parameters ρ and σ, we say that a graph G is (σ, ρ)- perfect if σ(H) = ρ(H) for every non-trivial connected induced subgraph H of G. In this work we characterize (γw, τ )-perfect graphs, (γw, α′)-perfect graphs, and (α′, τ )-perfect graphs, where γw(G), τ (G) and α′(G) denote the weakly connected domination number, the vertex cover number and the matching number of G, respectively. Moreover,...
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The EU Tyre Noise Label: The problem with measuring the noise level of only a few of all tyre variants
PublicationThe STEER project, described in another Inter-Noise 2022 paper, has evaluated the performance of the noise label of the European tyre label. The major finding was that uncertainties of the tyre/road noise measurements were higher than should be accepted. One of the worst uncertainty sources was found to be the common practice to measure only some tyres of all sizes or variants within a tyre line, to save money. Generally, only...
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Head-Space SPME for the Analysis of Organophosphorus Insecticides by Novel Silica IL-Based Fibers in Real Samples
PublicationThis work demonstrates the suitability of a newly developed ionic liquid (IL)-based silica SPME fiber for the determination of seven organophosphorus insecticides in cucumber and grapefruit samples by headspace solid-phase microextraction (HS-SPME) with a gas chromatography–flame ionization detector (FID). The sol-gel method released four different sorbent coatings, which were obtained based on a silica matrix containing ILs immobilized...