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Wyniki wyszukiwania dla: SMART INNOVATION ENGINEERING PRODUCT INNOVATION PRODUCT DESIGN SET OF EXPERIENCE DECISIONAL DNA
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Naturally occurring mitochondrial DNA heteroplasmy in the MRL mouse
PublikacjaThe MRL/MpJ mouse is an inbred laboratory strain of Mus musculus, known to exhibit enhanced autoimmunity, increased wound healing, and increased regeneration properties. We report the full-length mitochondrial DNA (mtDNA) sequence of the MRL mouse (Accession # EU450583), and characterize the discovery of two naturally occurring heteroplasmic sites. The first is a T3900C substitution in the TpsiCloop of the tRNA methionine gene...
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The role of background color, interletter spacing, and font size on preferences in the digital presentation of a product
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Economic Aspects of Algae Biomass Harvesting for Industrial Purposes. The Life-Cycle Assessment of the Product
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A distillery by-product as an external carbon source for enhancing denitrification in mainstream and sidestream treatment processes
PublikacjaThe use of fusel oil as an 'alternative' carbon source for denitrification in the mainstream and sidestream treatment processes was studied. Research comprised two kinds of batch experiments as well as acclimation of process biomass to external carbon sources. In the conventional nitrate utilization rate (NUR) measurements (one-phase experiments with non-acclimated biomass), the NUR with fusel oil was 1.4-1.7 g N/(kg VSS•h which...
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Mapping negative unintended consequences of disruptive technologies use in smart cities
PublikacjaSmart cities governance (SCG) consists of both to foster technology-enabled innovation, and to utilize disruptive technologies (DT) outcomes and impacts to increase public value of urban services. Despite widespread discussion of DT benefits, scientific literature identifies multiple determinants of unintended negative consequences (UC) of DT deployment in smart city initiatives. By considering UC as the negative aspects resulting...
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The resilient city in architectural engineering education: a joint design studio between Gdańsk and Chalmers universities of technology
PublikacjaChallenges to society, such as those posed by climate change require a new approach to the education of the engineer-architect. Contemporary solutions should serve future generations and that is why the idea of the resilient city should be discussed and implemented, both in theory and in practice. It is necessary to teach students to design urban structures in such a way that they are resilient to dynamically changing conditions....
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Interaction Design in Agile IT Projects
PublikacjaIn recent years, interactive systems, such as various types of software, online services or mobile applications, have become an integral part of everyday life. Interactive systems and digital services should be easy to use and provide a positive User Experience (UX). For this reason, interaction design has recently emerged as a distinct professional area of information technology (IT). Easy interaction and user experience (UX)...
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Design thinking qualifications framework – standardizing the innovative approach to entrepreneurial education delivery to engineering students
PublikacjaHighly competitive labor market stimulates increasing expectations towards fresh university alumni. It is not enough to be an expert - well educated and often experienced - in chosen discipline. High variability of the business environment, continuous change, number of risks, together with higher work demand than supply, shape clear employers’ expectations: entrepreneurial employees are wanted. On this ground a need for entrepreneurial...
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ZARZADZANIE ORGANIZACJĄ TYPU SMART
PublikacjaZaprezentowano organizacji, w której charakterystykę wpisano następujące cechy: strategiczne uwarunkowanie, maksymalną innowacyjność, atrakcyjność dla interesariuszy, rozwijanie osobowości pracowników oraz twórczość w działaniu. Te atrybuty, tworzą koncepcję organizacji SMART (akronim od pierwszych liter powyższych cech), która wyróżnia się dodatkowo strukturą opartą o dynamicznie kreowane zespoły oraz skutecznym wspomaganiem...
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Application of Reverse Engineering Technology in Part Design for Shipbuilding Industry
PublikacjaIn the shipbuilding industry, it is difficult to create CAD models of existing or prototype parts, especially with many freeform surfaces. The paper presents the creation of the CAD 3D model of a shipbuilding component with the application of the reverse engineering technology. Based on the data obtained from the digitization process, the component is reconstructed in point cloud processing programs and the CAD model is created....
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Multi-fidelity aerodynamic design trade-off exploration using point-by-point Pareto set identification
PublikacjaAerodynamic design is inherently a multi-objective optimization (MOO) problem. Determining the best possible trade-offs between conflicting aerodynamic objectives can be computationally challenging when carried out directly at the level of high-fidelity computational fluid dynamics simulations. This paper presents a computationally cheap methodology for exploration of aerodynamic design trade-offs. In particular, point-by-point...
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A probabilistic model for accidental cargo oil outflow from product tankers in a ship–ship collision
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20-Hydroxyvitamin D3, a Product of Vitamin D3 Hydroxylation by Cytochrome P450scc, Stimulates Keratinocyte Differentiation
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Structural, spectroscopic, and computational characterization of the cleavage product of dimolybdenum(II) core under aerobic conditions
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Bio-inspired Urban Design: Smart Growth and Sustainable Development Frameworks for a New Urban Unit in Cracow
PublikacjaIn March 2012, architects João Diniz (Brazil) and Dorota Wiśniewska (Poland) answered a call to competition from the City of Cracow, submitting an entry for the redesign of 5600 ha of the Nowa Huta district in eastern Cracow, focusing on economic revitalization within a framework of smart growth and sustainable development. The scenario included an ArcerolMittal Steelworks and incorporated a strong ecological analysis for the easternmost...
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DNA modification by 1-nitroacridine derivatives. Comparison of 32P-Postlabeling and restriction enzyme analysis method for the detection of DNA adducts formed by 1-nitroacridines C-1748 and C-857
Publikacja4-podstawione 1-nitroakrydyny reprezentują nową grupę pochodnych akrydyny, zsyntetyzowanych na Politechnice Gdańskiej. Metoda 32P-postlabellingu wykazała, że pochodne C-1748 i C-857 tworzą od 4-6 adduktów DNA w systemie komórkowym i bezkomórkowym o innym rozkładzie plam chromatograficznych, jednakże niezależnym od zastosowanego systemu aktywacyjnego. Metoda enzymatycznej analizy restrykcyjnej pozwoliła natomiast śledzić kinetykę...
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The role of resilience in explaining hotel growth: A fuzzy-set QCA approach
PublikacjaPurpose: Due to the detrimental effects of the recent pandemic on the hotel sector, hotel resilience research and its impact on hotel recovery have received lots of academic attention. However, a sustainable perspective on hotel resilience, as an approach for investigating its impact on long-term hotel growth, has been largely overlooked in the hospitality resilience literature. Therefore, this paper aims to address the research...
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Smart Cities Concept: Smart Mobility Indicator
PublikacjaThis work attempts to analyze problems resulting from the lack of possibility to assess the effectiveness of the implementation of “Smart Mobility” solutions, which represent one of the cornerstones of Smart Cities, from the point of view of city hall offices. The work presents existing Smart Mobility evaluation solutions, discusses their drawbacks, and then proposes a new indicator. The final part of the work presents assumptions...
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Smart Services for Improving eCommerce
PublikacjaThe level of customer support provided by the existing eCom-merce solutions assumes that the person using the functionality of theshop has sufficient knowledge to decide on the purchase transaction. Alow conversion rate indicates that customers are more likely to seekknowledge about the particular product than finalize the transaction.This is facilitated by the continuous development of customers’ digi-tal...
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The significance of the underground experience: Selection of reference design cases from the underground public transport stations and interchanges of the European Union
PublikacjaAbstract Background Recent research into the way public transport users appreciate stations and interchanges has highlighted several key aspects. Importantly, the optimization of these facilities should not simply aim to resolve dissatisfiers, but should also focus on addressing satisfiers, through the incorporation of factors such as comfort and experience. ‘Soft requirements,’ which have emerged in architecture and urban design,...
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INDUSTRIAL CLUSTERS AS A DEVICE OF STIMULATION OF COOPERATION AND INNOVATION OF SMALL AND MEDIUM-SIZED ENTERPRISES IN THE AREA OF BIO-ECONOMY
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Editorial: Social, technological and health innovation: Opportunities and limitations for social policy, health policy, and environmental policy
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Interstrand crosslinking of DNA by C-1311 (Symadex) and other imidazoacridinones
PublikacjaImidazoakrydony, w tym pochodna C-1311 (Symadex) znajdująca się w pierwszej fazie badań klinicznych prowadzonych w USA, należą do grupy bardzo aktywnych związków przeciwnowotworowych zsyntetyzowanych w Katedrze Technologii Leków i Biochemii PG. Za pomocą zmodyfikowanej metody Parsons'a wykazaliśmy, że C-1311 indukuje, w sposób zależny od stężenia, międzyłańcuchowe wiązania sieciujące w komórkach różnych nowotworów ludzkiego pochodzenia...
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Electroanalytical and spectroscopic procedures for examination of interactions between double stranded DNA and intercalating drugs
PublikacjaPrzedstawiono metodę elektrochemicznego opisu oddziaływań dsDNA ze związkiem biologicznie czynnym w warunkach, w których zarówno badany związek jak i cząsteczka DNA są w roztworze elektrolitu. Opracowano warunki pomiaru, gdzie ani związek, ani DNA nie adsorbuje na elektrodzie. Wykazano, podobnie jak podczas badania innymi metodami, że oddziaływania są dwojakiego rodzaju: elektrostatyczne i poporzez interkalację.
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Why set of experience knowledge structure can be considered a knowledge representattion for formal decision events?
PublikacjaOmówiono zasady reprezentacji wiedzy przy pomocy zbioru dośwadczeń. Uzasadniono wybór takiej reprezentacji na tle badańliteraturowych.
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Gluten-Free Bread with Cricket Powder—Mechanical Properties and Molecular Water Dynamics in Dough and Ready Product
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The fixed state in impedance measurements of a two-step electrode reaction proceeding with accompanying adsorption of an intermediate product
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A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB*
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Design of knowledge based systems in environmental engineering.
PublikacjaW pracy omawia się konstrukcję samo narastającego modelu rozmytego zarządzania przedsięwzięciami informatycznymi, stosowanego do wspomagania wytwarzania systemów opartych na wiedzy. Proponowany model służy w szczególności do zarządzania zmianami finansowania i czasu realizacji projektów. Opiera się on na eksperymentalnej regułowej wiedzy, pochodzącej z realizacji zarządzania przedsięwzięciami informatycznymi, na teorii systemów...
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Design of knowledge-based systems in environmental engineering.
PublikacjaW pracy omawia się konstrukcję iteracyjnie dostrajającego się modelu rozmytego zarządzania przedsięwzięciami informatycznymi, stosowanego do wspomagania wytwarzania systemów opartych na wiedzy. Proponowany model służy w szczególności do zarządzania zmianami finansowania i czasu realizacji projektów dotyczących m.in. systemów wykorzystywanych w (inżynierii) ochronie środowiska. Struktura tego modelu zasadza się na teorii systemów...
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Information significance in engineering design processes in shipyards
PublikacjaW artykule zwrócono uwagę na aspekt zarządzania procesem budowy statku, zarządzania informacją w procesie projektowania oraz znaczeniu systemów informacyjnych w transmisji informacji pomiędzy biurem projektowym a organizacjami współpracującymi. Dzięki jednolitej informacji projektowej we wszystkich fazach projektowania uzyskujemy ciągłość procesu projektowego, eliminację niepotrzebnych kosztów związanych z poprawą błędów oraz lepszą...
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Two highly thermostable paralogous single-stranded DNA-binding proteins from Thermoanaerobacter tengcongensis
PublikacjaThe thermophilic bacterium Thermoanaerobacter tengcongensis has two single-stranded DNA-binding (SSB) proteins, designated TteSSB2 and TteSSB3. In a SSB complementation assay in Escherichia coli, only TteSSB3 took over the in vivo function of EcoSSB. We have cloned the ssb genes obtained by PCR and have developed E. coli overexpression systems. The TteSSB2 and TteSSB3 consist of 153 and 150 amino acids with a calculated molecular...
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Design of a Distributed System using Mobile Devices and Workflow Management for Measurement and Control of a Smart Home and Health
PublikacjaThe paper presents design of a distributed system for measurements and control of a smart home including temper- atures, light, fire danger, health problems of inhabitants such as increased body temperature, a person falling etc. This is done by integration of mobile devices and standards, distributed service based middleware BeesyCluster and a workflow management system. Mobile devices are used to measure the parameters and are...
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Interaction of antitumor triazoloacridone C-1305 and its analogs with telomeric DNA
PublikacjaBadaliśmy oddziaływanie pochodnej triazoloakrydonu C-1305 i jego bliskich analogów strukturalnych z oligonukleotydami zawierającycmi sekwencje telomerowe TTAGGG oraz oligonukleotydami sfałdowanymi w strukturę G-kwadrupleksu. Wykazaliśmy, że spośród badanych związków pochodna C-1305 wykazała największą specyficzność w stosunku do telomerowego DNA. Związek ten stabilizował także strukturę G-kwadrupleksu, podczas gdy jego analogi...
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In silico study on the effects of carbonyl groups on chemical equilibrium of reactions with a polar product occurring under confinement in pores of activated carbons
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Cellular senescence induced by DNA damage and its role in carcinogenesis and chemotherapy
PublikacjaUszkodzenia DNA indukują w komórce różne procesy, w tym starzenie komórkowe, co może uruchamiać proces karcinogenezy jak i być związane z odpowiedzią na leki przecinowotworowe. Biologiczna rola starzenia komórkowego nie jest jednak jasna. Zasugerowano, że proces starzenia komórkowego może hamować proces karcinogenezy poprzez indukcję nieodwracalnego zahamowania wzrostu przez czynniki genotoksyczne. Indukcja starzenia komórkowego...
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Treatment innovation using solar/UV In book: The Treatment of Pharmaceutical Wastewater: Innovative Technologies and the Adaptation of Treatment Systems
PublikacjaSince ancient times, sunlight irradiation has been widely used for water purification. Apart from solar water disinfection techniques, UV irradiation is of particular interest when considering the photodegradation of various classes of emerging pollutants. Pharmaceutically active compounds are one of the largest classes of micropollutants. The main sources of these contaminants in wastewater and aqueous environments are households,...
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Using the social return on investment (SROI) as a measure of the effectiveness of social innovation projects implemented under public policies
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Defining the smart-city in the context of regenerative design and planning
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Accelerated large scale test set-up design in natural corrosion marine environment
PublikacjaThe standards for conducting small-scale specimen tests are well developed, but there is a lack of direct guidelines for conducting corrosion tests for large-scale specimens. The objective here is to develop a methodology which may be used in designing an accelerated corrosion test of large-scale structural components subjected to a natural corrosion marine environment. Different factors influencing corrosion degradation of steel...
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ADAPTATION OF ENGINEERING FEA-BASED ALGORITHMS TO LCF FAILURE AND MATERIAL DATA PREDICTION IN OFFSHORE DESIGN
PublikacjaThere is an ever growing industrial demand for quantitative assessment of fatigue endurance of critical structural details. Although FEA-based calculations have become a standard in engineering design, problems involving the Low-To-Medium cycle range (101-104) remain challenging. This paper presents an attempt to optimally choose material data, meshing density and other algorithm settings in the context of recent design of the...
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Open-Set Speaker Identification Using Closed-Set Pretrained Embeddings
PublikacjaThe paper proposes an approach for extending deep neural networks-based solutions to closed-set speaker identification toward the open-set problem. The idea is built on the characteristics of deep neural networks trained for the classification tasks, where there is a layer consisting of a set of deep features extracted from the analyzed inputs. By extracting this vector and performing anomaly detection against the set of known...
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Single-phase product obtained via crude glycerine depolymerisation of polyurethane elastomer: structure characterisation and rheological behaviour
PublikacjaPolyurethane recycling is a topic of growing interest due to the increasing amount of polyurethanewaste. The main purpose of polyurethane feedstock recycling is to recover the starting polyol, a valuable material. In thiswork, amethod of polyurethane thermo-chemical recycling, glycerolysisbymeansof crude glycerine, is proposed. Themaineffort is focusedonthe employment of crude glycerine without purification from biodiesel production...
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Changes in chemical composition and oxidative stability of cold-pressed oils obtained from by-product roasted berry seeds
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The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
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Molecular mechanism and energetics of coupling between substrate binding and product release in the F 1 -ATPase catalytic cycle
PublikacjaF1-ATPase is a motor protein that couples the rotation of its rotary γ subunit with ATP synthesis or hydrolysis. Single-molecule experiments indicate that nucleotide binding and release events occur almost simultaneously during the synthesis cycle, allowing the energy gain due to spontaneous binding of ADP to one catalytic β subunit to be directly harnessed for driving the release of ATP from another rather than being dissipated...
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Commercial function as a treat to the monument - 25 years of experience in the commercialization of monuments in Gdansk, Poland
PublikacjaThe principles of the market economy adopted in Poland in the nineties have significantly touched the resources of immovable monuments. As a result, monuments have become a product of culture subject to the rules of the free market; and state ownership, patronage and decision-making practice has now been replaced by private interest. Practical monument use has also changed with the shift in ownership of objects after privatization...
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Ontology-Aided Software Engineering
PublikacjaThis thesis is located between the fields of research on Artificial Intelligence (AI), Knowledge Representation and Reasoning (KRR), Computer-Aided Software Engineering (CASE) and Model Driven Engineering (MDE). The modern offspring of KRR - Description Logic (DL) [Baad03] is considered here as a formalization of the software engineering Methods & Tools. The bridge between the world of formal specification (governed by the mathematics)...
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Comet assay-based methods for measuring DNA repair in vitro; estimates of inter- and intra-individual variation.
PublikacjaZdolność do naprawy uszkodzeń DNA jest jednym z najważniejszych wyznaczników podatności na choroby nowotworowe. Dlatego też użytecznym staje się możliwość pomiaru stopnia naprawy DNA w próbkach materiału badawczego pobranego od ochotników. Celem pracy było, po pierwsze, opracowanie w warunkach in vitro prostej metody (z wykorzystaniem techniki testu kometowego), w której naprawa DNA odbywa się poprzez wycinanie nukleotydów (NER)....
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Design and Utility of Specialist Comminution Set-Up for Plastics and Organic Materials
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