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Wyniki wyszukiwania dla: Krystyna Lars-Chwin
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Automatyzacja Procesów Biznesowych2023
Kursy OnlineKurs aktualnie wykorzystywany dla Informatyka II stopnia, studia magisterskie dzienne PL - prowadzący K.Dziubich
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WM - MiBM gr. 2 i 3 - Matematyka 2017/2018 (K.Dąbrowska)
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WILiŚ - GiK - Matematyka 2018/2019 (K.Dąbrowska)
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Polityka Publiczna MSU (zima 2022_23)
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WILiŚ - GiK - Matematyka 2017/2018 (K.Dąbrowska)
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WILiŚ - Bud. i IŚ - zaoczne - Matematyka 2018/2019 (K.Dąbrowska)
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WILiŚ - Bud. - Matematyka 2018/2019 (K.Dąbrowska)
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Automation of Business Processes- acitve
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WM - MiBM sem. III - Matematyka 2019/2020 (K.Dąbrowska)
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Automation of Business Processes_2023
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WM - MiBM, ZiIP sem. III gr.2,3,4,5 - Matematyka 2017/2018
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Automatyzacja Procesów Biznesowych - aktywny
Kursy OnlineKurs aktualnie wykorzystywany dla Informatyka II stopnia, studia magisterskie dzienne PL - prowadzący K.Dziubich
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WM - MiBM - Matematyka 2018/2019 (K.Dąbrowska)
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WILiŚ - Budownictwo i Inżynieria Środowiska - zaoczne - Matematyka 2017/2018 (K.Dąbrowska)
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Polityka Publiczna AG I NS (zima 2023/24)
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WILiŚ - Tr. gr. 2 i 3 - Matematyka 2016/17 (K.Dąbrowska)
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Polityka Publiczna AG I S (zima 2023/34)
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Automatyzacja procesów biznesowych (2024)
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Automation of Business Processes (2024)
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WOiO - SO gr. 4 i 5 - Matematyka 2016/17 (K.Dąbrowska)
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Historia Gospodarcza (zima 2023_24)
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WM - MiBM gr. 3, 4 - Matematyka 2016/17 (K.Dąbrowska)
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Investigations on the immunosuppressive activity of derivatives of mycophenolic acid in immature dendritic cell
PublikacjaThe main activity of mycophenolic acid (MPA) and its analogs is the inhibition of proliferation of T cells. Here, we hypothesized that MPA and its conjugates inhibits also the activity of antigen-presenting cells (APC) including dendritic cells (DCs). We tested the effect of novel amino acid derivatives of MPA and conjugates of MPA with acridines/acridones on DCs by flow cytometry, ELISA and MLR assay. Both acridines/acridone derivatives...
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Chromatografia w układzie faz odwróconych.
PublikacjaOpisano fazy stacjonarne stosowane w chromatograficznych układach faz odwróconych. Opisano mechanizm retencji substancji i wpływ stosowanych rozpuszczalników na selektywność rozdzielania substancji.
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Krystyna Kruczalak
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Pilicides effectively hinder chaperone-usher interactions in all Gram-negative bacteria
PublikacjaThe chaperone-usher pathway of adhesive structures biogenesis is highly conserved in all Gram-negative bacteria. Pili are polymers of thousands protein subunits that possess conserved immunoglobuline-like structure denoted by lack of the seventh G strand. The effect of this structural defect is a hydrophobic acceptor cleft. The folding of protein subunits is strictly dependent on the action of specific periplasmic chaperone protein...
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Gazeta Uniwersytecka: Pismo Społeczności Akademickiej Uniwersytetu Gdańskiego: wydanie specjalne: Świat Miłosza
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Synthesis and biological evaluation of novel analogues of batracylin with synthetic amino acids and adenosine: an unexpected effect on centromere segregation in tumor cells through a dual inhibition of topoisomerase IIa and Aurora B
PublikacjaIn the search for new anticancer agents we designed and synthesized batracylin derivatives with linking synthetic amino acid side chains of different lengths and adenosine. Unexpectedly, we have found that in water and the culture media adenosine–amino acid–BAT conjugates form supramolecular structures and this prevents these compounds from entering cells. Consequently, these compounds exerted no biological activity when tested...
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Human carnosinases: A brief history, medicinal relevance, and in silico analyses
PublikacjaCarnosine, an endogenous dipeptide, has been found to have a plethora of medicinal properties, such as antioxidant, antiageing, and chelating effects, but with one downside: a short half-life. Carnosinases and two hydrolytic enzymes, which remain enigmatic, are responsible for these features. Hence, here we emphasize why research is valuable for better understanding crucial concepts like ageing, neurodegradation, and cancerogenesis,...
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A High-Arctic flow-through lake system hydrochemical changes: Revvatnet, southwestern Svalbard (years 2010–2018)
PublikacjaLake ecosystems are strongly coupled to features of their surrounding landscapes such as geomorphology, lithology, vegetation and hydrological characteristics. In the 2010–2018 summer seasons, we investigated an Arctic flow-through lake system Revvatnet, located in the vicinity of the coastal zone of Hornsund fjord in Svalbard, characterising its hydrological properties and the chemical composition of its waters. The lake system...
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Synthesis and Biological Evaluation of Acridine/Acridone Analogs as Potential Anticancer Agents
PublikacjaAcridine and acridone analogues were prepared by Ullmann condensation and then cyclization reaction. As a result of nucleophilic substitution reaction 1-nitro-9-phenoxyacridine or 1-chloro-4-nitro-9(10H)-acridone with the corresponding peptides, the planned acridine derivatives (10a-c, 12, 17-a-d, 19) have been obtained. The cytotoxic activity of the newly obtained analogs were evaluated against melanotic (Ma) and amelanotic (Ab)...
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Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated /N-Tiophosphorylated Tacrine
PublikacjaNovel phosphorus and thiophosphorus tacrine derivatives were designed, synthesized and their biological activity and molecular modeling was investigated as a new potential anti-Alzheimer's disease (AD) agents. All new synthesized compound exhibited lower toxicity against neuroblastoma cell line (SH-SY5Y) in comparison with tacrine. Two analogues in the series, 7 and 9, demonstrated lack of cytotoxicity against hepatocellular cells...
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Design, synthesis and biological evaluation of novel N-phosphorylated and O-phosphorylated tacrine derivatives as potential drugs against Alzheimer’s disease
PublikacjaIn this work, we designed, synthesised and biologically investigated a novel series of 14N- and O-phosphorylated tacrine derivatives as potential anti-Alzheimer’s disease agents. In the reaction of 9-chlorotacrine and corresponding diamines/aminoalkylalcohol we obtained diamino and aminoalkylhydroxy tacrine derivatives. Next, the compounds were acid to give final products 6–13 and 16–21 that were characterised by 1H, 13 C, 31P...
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Low temperature processed MnCo2O4 and MnCo1.8Fe0.2O4 as effective protective coatings for solid oxide fuel cell interconnects at 750 °C
PublikacjaIn this study two materials, MnCo2O4 and MnCo1.8Fe0.2O4 are studied as potential protective coatings for Solid Oxide Fuel Cell interconnects working at 750 °C. First powder fabrication by a modified Pechini method is described followed by a description of the coating procedure. The protective action of the coating applied on Crofer 22 APU is evaluated by following the area specific resistance (ASR) of the scale/coating for 5500...
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Thick - film and LTCC multicontact resistors - preliminary results
PublikacjaW artykule zaprezentowano i skomentowano wstępne wyniki elektryczxnych i geometrycznych charakterystyk wielokontaktowychstruktur rezystywnych wykonanych w technologiigrubowarstwowej i LTCC ( ceramicznej z niską temperatura wypadaniz). Realizowane struktury miały rozmiary od 200 x 100 μm2 do 1500 x 500 μm2 i 3 lub 6 kontaktów rozmieszczonych e różny sposób na obwodzie warstwy rezystywnej.
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Nickel Oxide Thin Film Sensor for Fluctuation-Enhanced Gas Sensing of Formaldehyde
PublikacjaNanocrystalline nickel-oxide-based thin films were prepared by advanced reactive gas deposition, and the response of these films to formaldehyde was studied by fluctuationenhanced sensing. Morphological and structural analyses showed porous deposits of nickel oxide particles with face-centered cubic structure. Resistance fluctuations were measured upon exposure to ethanol, formaldehyde and methane at 200 °C. Power density spectra...
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Fluctuation-enhanced and conductometric gas sensing with nanocrystalline NiO thin films: A comparison
PublikacjaNanocrystalline thin films of NiO were prepared by advanced reactive gas deposition, and their responses to formaldehyde, ethanol and methane gases were studied via fluctuation-enhanced and conductometric methods Thin films with thicknesses in the 200–1700-nm range were investigated in as-deposited form and after annealing at 400 and 500 °C. Morphological and structural analyses showed porous deposits with NiO nanocrystals having...
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Natalia Krystyna Gietka dr inż.
OsobyOd 2014 roku pracownik Wydziału Inżynierii Lądowej i Środowiska Politechniki Gdańskiej. Obecnie adiunkt w Katedrze Geotechniki i Inżynierii Wodnej, w której rozwija swoje zainteresowania naukowe związane z dziedziną hydrauliki, mechaniki płynów, meteorologii i hydrologii. Wraz z Centrum Nowoczesnej Edukacji dąży do wprowadzania innowacyjnych rozwiązań w nauczaniu np. poprzez prowadzenie zajęć w formie grywalizacji na kierunku Inżynieria...
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Evaluation of the use of reindeer droppings for monitoring essential and non-essential elements in the polar terrestrial environment
PublikacjaExcess or toxic metals, non-metals and metalloids can be eliminated from the organism by deposition in inert tissue (e.g. fur) or excretion with body secretions, urine and faeces. Droppings are one of the main routes for the elimination of multiple elements and they can be collected without direct contact with the animal. Contaminant concentration has been examined in non-lethally collected tissues of several species (especially...
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Free Satellite Imagery for Monitoring Reclaimed Sulphur Mining Region Tarnobrzeg, Poland
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Temporal Satellite Images in The Process of Automatic Efficient Detection of Changes of the Baltic Sea Coastal Zone
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Konstrukcje Betonowe II - wykład 2022/2023
Kursy OnlineKonstrukcje betonowe II - wykład 2022/2023 wykłady: prof. dr hab. inż. Krystyna Nagrodzka-Godycka e-mail: ngodyc@pg.edu.pl Wykład w semestrze letnim odbywać się będzie - zgodnie z planem zajęć dla VI sem. studiów I stopnia, stacjonarnych w środy, w godz. 9:15- 12:00 w formie stacjonarnej w Aditorium Novum KBII w - w jest wykładem obowiązkowym dla studentów VI semestru studiów I stopnia, stacjonarnych. Zaliczenie wykładów...
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Rhamnolipid CMC Prediction
PublikacjaRelationships between the purity, pH, hydrophobicity (log Kow) of the carbon substrate, and the critical micelle concentration (CMC) of rhamnolipid type biosurfactants (RL) were investigated using a quantitative structure–property relationship (QSPR) approach and are presented here for the first time. Measured and literature CMC values of 97 RLs, representing biosurfactants at different stages of purification, were considered....
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Experimental analysis of coefficients of local resistance on elbows in multilayer pipe systems
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Wpływ dodatku odcieków ze składowisk odpadów komunalnych na efektywność pracy komunalnej oczyszczalni ścieków: badania modelowe
PublikacjaW pracy badano wpływ dodatku odcieków ze składowisk odpadów komunalnych na efektywność oczyszczania ścieków z komunalnej oczyszczalni. Badania prowadzone były w skali laboratoryjnej w układzie A2/O, który zapewnia usuwanie związków azotu i fosforu. Układ typu A2/O, składał się z następujących po sobie komór: beztlenowej, anoksycznej i tlenowej. Czas zatrzymania w poszczególnych komorach wynosił odpowiednio: 3,5h w komorze beztlenowej,...
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Anthropopressure’s intensification with reference to Arctic ecosystems
PublikacjaThis paper concerns issue of long range atmospheric transport of pollutants to polar areas and intensification of their toxic effect on biota in the face of climate change. Arctic which was for years seen as a pristine and not affected by antropopressure region became a sink of xenobiotics. Atmospheric circulation facilitates transport of chemicals from Eurasia to Arctic. Influence of climate change on crucial balance of polar...
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Organic Pollution in Surface Waters from the Fuglebekken Basin in Svalbard, Norwegian Arctic
PublikacjaThe Fuglebekken basin is situated in the southern part of the island of Spitsbergen (Norwegian Arctic), on the Hornsund fjord (Wedel Jarlsberg Land). Surface water was collected from 24 tributaries (B1-B24) and from the main stream water in the Fuglebekken basin (25) between 10 July 2009 and 30 July 2009. The present investigation reveals the results of the analysis of these samples for their PAH and PCB content. Twelve of 16 PAHs...
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Evaluation of Medical Staff Satisfaction for Workplace Architecture in Temporary COVID-19 Hospital: A Case Study in Gdańsk, Poland
PublikacjaThis article analyses the architecture that was used in the temporary AmberExpo hospital in Gdańsk, Poland which was installed during the COVID-19 pandemic. The construction of this type of facility is often based on experimental approaches, aimed at caring for patients suffering from an infectious disease in emergency conditions. In order to assess the level of employee satisfaction with the architectural and technical elements...
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Long-Term Impact of Wind Erosion on the Particle Size Distribution of Soils in the Eastern Part of the European Union
PublikacjaWind erosion is the leading cause of soil degradation and air pollution in many regionsof the world. As wind erosion is controlled by climatic factors, research on this phenomenon isurgently needed in soil and land management in order to better adapt to climate change. In thispaper, the impact of wind erosion on the soil surface in relation to particle size distribution wasinvestigated. Changes in percentage of sand, silt and...
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....