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Wyniki wyszukiwania dla: NATURAL MEDICINE
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Angiopoietin-like growth factor-derived peptides as biological activators of adipose-derived mesenchymal stromal cells
PublikacjaAdipose-derived mesenchymal stromal cells (AD-MSCs) are an essential issue in modern medicine. Extensive preclinical and clinical studies have shown that mesenchymal stromal/stem cells, including AD-MSCs, have specific properties (ability to differentiate into other cells, recruitment to the site of injury) of particular importance in the regenerative process. Ongoing research aims to elucidate factors supporting AD-MSC culture...
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Antimicrobial Activity of Honey
PublikacjaHoney has had a valued place in traditional medicine for centuries. It was used to overcome liver, cardiovascular and gastrointestinal problems and for treatment of some types of infectious disease. Particularly, good results were achieved in the case of application of this product for therapy of infected, difficult to heal wounds. The high health-promoting properties of honey have been recently confirmed in many research investigations....
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Imunofan—RDKVYR Peptide—Stimulates Skin Cell Proliferation and Promotes Tissue Repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today’s science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical specialties. In this study, we...
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A competition between two- and three-body dissociation channels in photo-double-ionization of tetrahydro-2H-pyran and 3,4-dihydro-2H-pyran molecules
PublikacjaVarious molecules possess structures consisting of the heterocyclic rings containing oxygen atoms. These substances often play a significant role in many different fields of chemistry, medicine, and biology. Due to a specific atomic composition and bond arrangement, many of these molecules retain unique electronic properties, which may be probed by diverse spectroscopic techniques, including those utilizing synchrotron radiation....
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Active Dynamic Thermography imaging of wound healing processes in cardio surgery
PublikacjaThe surgery is a branch of medicine, that is integrally connected to wounds. Despite using sterile tools and compliance with aseptic rolls, some of the surgery wounds become infected. In clinical practice there is a lack of cheap, objective methods and tools for quantitative definition and estimation of the surgery wound healing progress. This paper presents preliminary results of Active Dynamic Thermography (ADT) parametric imaging...
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Selected organophosphorus compounds with biological activity. Applications in medicine
PublikacjaThe purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...
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A history of the physical and chemical stability of pharmaceuticals : a review
Publikacja: There is a great need for a broad range review of stability tests of active pharmaceutical ingredients (APIs) in comparison with current requirements contained in the pharmacopoeia. This review focuses on a pharmaceutical history of physical and chemical stability determination. Traditional knowledge must be considered in the context of physical stability, while new knowledge must be applied and acquired in terms of identification...
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Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...
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Bacterial nanocellulose as a microbiological derived nanomaterial
PublikacjaBacterial nanocellulose (BNC) is a nanofibrilar polymer produced by strains such as Gluconacetobacter xylinus, one of the best bacterial species which given the highest efficiency in cellulose production. Bacterial cellulose is a biomaterial having unique properties such as: chemical purity, good mechanical strength, high flexibility, high absorbency, possibility of forming any shape and size and many others. Such a large number...
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Human carnosinases: A brief history, medicinal relevance, and in silico analyses
PublikacjaCarnosine, an endogenous dipeptide, has been found to have a plethora of medicinal properties, such as antioxidant, antiageing, and chelating effects, but with one downside: a short half-life. Carnosinases and two hydrolytic enzymes, which remain enigmatic, are responsible for these features. Hence, here we emphasize why research is valuable for better understanding crucial concepts like ageing, neurodegradation, and cancerogenesis,...
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3D Printing of Metallic Implants
PublikacjaThe fabrication of various elements, solid and open porous structures of stainless steel and Ti alloy is described. The process was started with the design of 3D models in CAD/CAM system. The 3D models were transformed into *.stl files and then the manufacturing process of the real structures by means of the selective laser melting with the SLM Realizer 100 3D printer was made. The paper shows the porous specimens made for possible...
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Label‐free optical detection of cyclosporine in biological fluids
PublikacjaIn this paper, a spectroscopic method for determination of cyclosporine concentrations in biological fluids is presented. Blood plasma and hemoglobin solutions are chosen for the experiment. For various cyclosporine concentrations in blood plasma and hemoglobin, absorbance measurements in spectra range from 600 to 1100 nm are performed. The measurement results are analyzed by the use of a dedicated algorithm. The obtained data...
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Problems of Active Dynamic Thermography Measurement Standardization in Medicine
PublikacjaReliability of thermographic diagnostics in medicine is an important practical problem. In the field of static thermography, a great deal of effort has been made to define the conditions for thermographic measurements, which is now the golden standard for such research. In recent years, there are more and more reports on dynamic tests with external stimulation, such as Active Dynamic Thermography, Thermographic Signal Reconstruction...
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Allergic reactions as a defense of the organism to the influence of implants components made of stainless steel
PublikacjaDue to the increasing number of cases of hypersensitivity caused by direct contact with metals, as well as the increasing demand for implants in humans all ages numerous studies on the effects of the impact of implant components are being carried out. The paper presents the phenomenon of etiology of allergy in general terms and in relation to the biomaterials used in medicine. There have been characterized in terms of impact on...
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Allergic Reactions as a Defense of the Organism to the Influence of Implants Components Made of Stainless Steel
PublikacjaDue to the increasing number of cases of hypersensitivity caused by direct contact with metals, as well as the increasing demand for implants in humans all ages numerous studies on the effects of the impact of implant components are being carried out. The paper presents the phenomenon of etiology of allergy in general terms and in relation to the biomaterials used in medicine. There have been characterized in terms of impact on...
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Thermoplastic elastomer filaments and their application In 3D printig
PublikacjaThe paper provides an overview on the materials used in the 3D printing technology (the Polish and foreign market) with a particular focus on flexible filaments and their possible application in the industry. There are described the techniques of 3D printing and modern filaments available on the market. There is observed the increase of interest in the production of products from filaments based on thermoplastic elastomers (TPE),...
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Polyurethanes Crosslinked with Poly(vinyl alcohol) as a Slowly-Degradable and Hydrophilic Materials of Potential Use in Regenerative Medicine
PublikacjaNovel, slowly-degradable and hydrophilic materials with proper mechanical properties and surface characteristics are in great demand within the biomedical field. In this paper, the design, synthesis, and characterization of polyurethanes (PUR) crosslinked with poly(vinyl alcohol) (PVA) as a new proposition for regenerative medicine is described. PVA-crosslinked PURs were synthesized by a two-step polymerization performed in a solvent...
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Parameters optimization in medicine supporting image recognition algorithms
PublikacjaIn this paper, a procedure of automatic set up of image recognition algorithms' parameters is proposed, for the purpose of reducing the time needed for algorithms' development. The procedure is presented on two medicine supporting algorithms, performing bleeding detection in endoscopic images. Since the algorithms contain multiple parameters which must be specified, empirical testing is usually required to optimise the algorithm's...
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Data Domain Adaptation in Federated Learning in the Breast Mammography Image Classification Problem
PublikacjaWe are increasingly striving to introduce modern artificial intelligence techniques in medicine and elevate medical care, catering to both patients and specialists. An essential aspect that warrants concurrent development is the protection of personal data, especially with technology's advancement, along with addressing data disparities to ensure model efficacy. This study assesses various domain adaptation techniques and federated...
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Upper Limb Bionic Orthoses: General Overview and Forecasting Changes
PublikacjaUsing robotics in modern medicine is slowly becoming a common practice. However, there are still important life science fields which are currently devoid of such advanced technology. A noteworthy example of a life sciences field which would benefit from process automation and advanced robotic technology is rehabilitation of the upper limb with the use of an orthosis. Here, we present the state-of-the-art and prospects for development...
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Application of bioassays in studies on the impact of pharmaceuticals on the environment
PublikacjaDrug interactions are often desirable particularly in medicine, when treatment of a patient requires using a mixture of drugs in specific doses to produce the adequate therapeutic effect. Unfortunately, interactions between drugs in the environment are not as desirable, despite the fact that drugs are present in the environment at low concentration levels [1]. Pharmaceuticals are present in the environment in a mixture of compounds,...
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A Measurement System for Quasi-Spectral Determination of Absorption and Scattering Parameters of Veterinary Tissue Phantoms
PublikacjaThis paper describes the construction of a system for the quasi-spectral determination of absorption and scattering parameters of animal tissue phantoms. Several tissue phantoms, including one reference and two modified for examination, were prepared from polydimethylsiloxane (PDMS). The phantoms were measured using a system based on an integrating sphere and the light sources of wavelengths commonly used for the treatment of various...
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The structure of novel polyurethanes containing synthetic poly[(R,S)-3-hydroxybutyrate]
PublikacjaThe aim of this study was to estimate the structure of new polyurethanes with the potential to be used in medicine. Atactic poly[(R,S)-3-hydroxybutyrate], obtained via a ring-opening polymerization, and polycaprolactonediol or polyoxytetramethylenediol were used to built the soft segments. 4,4'-methylene dicyclohexyl diisocyanate and 1,4-butanediol were the components to form hard segments. Polyurethanes with low-molecular weight...
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Recent total cross section measurements in electron scattering from molecules
PublikacjaThe grand-total cross sections (TCSs) for electron scattering from a range of molecules, measured over the period 2009-2019 in various laboratories, with the use of different electron transmission systems, are reviewed. Where necessary, the presented TCS data are also compared to earlier results. Collection of investigated molecular targets (biomolecules, biofuels, molecules of technological application,hydrocarbons) reflects their...
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Graphene Production and Biomedical Applications: A Review
PublikacjaGraphene is a two-dimensional nanomaterial composed of carbon atoms with sp2 hybrid orbitals. Both graphene and graphene-based composite have gained broad interest among researchers because of their outstanding physiochemical, mechanical, and biological properties. Graphene production techniques are divided into top-down and bottom-up synthesis methods, of which chemical vapor deposition (CVD) is the most popular. The biomedical...
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MACHINE LEARNING SYSTEM FOR AUTOMATED BLOOD SMEAR ANALYSIS
PublikacjaIn this paper the authors propose a decision support system for automatic blood smear analysis based on microscopic images. The images are pre-processed in order to remove irrelevant elements and to enhance the most important ones - the healthy blood cells (erythrocytes) and the pathologic (echinocytes). The separated blood cells are analyzed in terms of their most important features by the eigenfaces method. The features are the...
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Polysaccharide-based electroconductive hydrogels: Structure, properties and biomedical applications
PublikacjaArchitecting an appropriate platform for biomedical applications requires setting a balance between simplicity and complexity. Polysaccharides (PSAs) play essential roles in our life in food resources, structural materials, and energy storage capacitors. Moreover, the diversity and abundance of PSAs have made them an indispensable part of food ingredients and cosmetics. PSA-based hydrogels have been extensively reviewed in biomedical...
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Difference in Perceived Speech Signal Quality Assessment Among Monolingual and Bilingual Teenage Students
PublikacjaThe user perceived quality is a mixture of factors, including the background of an individual. The process of auditory perception is discussed in a wide variety of fields, ranging from engineering to medicine. Many studies examine the difference between musicians and non-musicians. Since musical training develops musical hearing and other various auditory capabilities, similar enhancements should be observable in case of bilingual...
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A new diagnostic method for evaluation of cardiosurgery wound healing
PublikacjaOne of important and still unsolved problems in medicine is the question of objective and quantitative evaluation of post-surgery wound healing. The aim of this research is to analyse possibility and value of using the newly elaborated infrared imaging procedure – Active Dynamic Thermography (ADT) – for quantitative description of wound healing processes in cardiosurgery. Both, classical thermal figures of merit as well as ADT...
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Optimization of Graphene Oxide Synthesis and Its Reduction
PublikacjaIn this article, we present the review of the chemical methods of synthesis of graphene oxide and its reduction in order to obtain the so-called reduced graphene oxide (rGO) whose properties are similar to those of pure graphene. We also present our experiments and the results in this field and the comparison of the efficiency of different methods of synthesis as well as the reduction of graphene oxide. To characterize the obtained...
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Computer Supported Analysis of the Human Body Surface Area
PublikacjaRecent scientific studies show the growing importance of the coefficients: BSA and TBSA, as an alternative to the widely used BMI. The relevant indicators are widely used in medicine, including such areas as: the treatment of burns, chemotherapy, dermatology and toxicology; as benchmarks when calculating doses of drugs and fluids. The particular problems concerning this subject are: the change of the reference parameter value which...
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Nanoparticles: Synthesis, characteristics, and applications in analytical and other sciences
PublikacjaNanoparticles (NPs) are widely employed in different research areas, ranging from analytical chemistry and environmental science to medicine, the agriculture and pharmaceutical industry. This is mainly due to the unique characteristics of NPs and the novelty they introduce in such applications. In analytical chemistry, the role of NPs can differ depending on the nature of the steps involved in analytical process. NPs are probably...
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Application of magnetic nanoparticles for magnetic solid-phase extraction in preparing biological, environmental and food samples
PublikacjaThe need to obtain meaningful results as the basis for determining the content of trace amounts of analytes has become the driving force behind the development of modern analytical techniques, including sample-preparation techniques, such as solid-phase extraction (SPE). Recently, great interest was aroused in the use of magnetic nanoparticles (MNPs) in SPE. These materials exhibit high selectivity, and, in small amounts, can provide...
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Bacterial cellulose in the field of wound healing and regenerative medicine of skin: recent trends and future prospectives
PublikacjaIn this overview, we focused on the bacterial cellulose (BC) applications, described in recently published scientific papers, in the field of skin regenerative medicine and wound care industry. Bacterial cellulose was proven to be biocompatible with living tissues. Moreover, its mechanical properties and porous structure are considered to be suitable for biomedical applications. It is due to the fact that porous structure of bacterial...
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Indoor air quality in public utility environments-a review
PublikacjaIndoor air quality has been the object of interest for scientists and specialists from the fields of science such as chemistry, medicine and ventilation system design. This results from a considerable number of potential factors, which may influence the quality of the broadly understood indoor air in a negative way. Poor quality of indoor air in various types of public utility buildings may significantly affect an increase in the...
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Ultrasonic Tomography of Brick Columns Based on FEM Calculations
PublikacjaUltrasonic tomography is one of the most developed method of non-destructive testing. Despite being used mainly in medicine, it is becoming more and more popular as a method for monitoring of structural elements. It allows to examine the internal structure and technical condition of the tested element. This paper investigates the influence of crosssectional geometry on an obtained tomographic image. Wave propagation signals were...
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Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency
PublikacjaOxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent the development of various adverse symptoms. Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms. Due to antioxidant activity, it also has the ability to scavenge the oxygen free radicals...
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Scaling Up the Process of Titanium Dioxide Nanotube Synthesis and Its Effect on Photoelectrochemical Properties
PublikacjaIn this work, for the first time, the influence of scaling up the process of titanium dioxide nanotube (TiO2NT) synthesis on the photoelectrochemical properties of TiO2 nanotubes is presented. Titanium dioxide nanotubes were obtained on substrates of various sizes: 2 × 2, 4 × 4, 5 × 5, 6 × 6, and 8 × 8 cm2. The electrode material was characterized using scanning electron microscopy as well as Raman and UV–vis spectroscopy in order...
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Assessment Of the Relevance of Best Practices in The Development of Medical R&D Projects Based on Machine Learning
PublikacjaMachine learning has emerged as a fundamental tool for numerous endeavors within health informatics, bioinformatics, and medicine. However, novices among biomedical researchers and IT developers frequently lack the requisite experience to effectively execute a machine learning project, thereby increasing the likelihood of adopting erroneous practices that may result in common pitfalls or overly optimistic predictions. The paper...
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A Comprehensive Review of Phytonutrients as a Dietary Therapy for Obesity
PublikacjaObesity is a complex medical condition mainly caused by eating habits, genetics, lifestyle, and medicine. The present study deals with traditional diets like the Mediterranean diet, Nordic diet, African Heritage diet, Asian diet, and DASH, as these are considered to be sustainable diets for curing obesity. However, the bioavailability of phytonutrients consumed in the diet may vary, depending on several factors such as digestion...
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A new quaternion-based encryption method for DICOM images
PublikacjaIn this paper, a new quaternion-based lossless encryption technique for digital image and communication on medicine (DICOM) images is proposed. We have scrutinized and slightly modified the concept of the DICOM network to point out the best location for the proposed encryption scheme, which significantly improves speed of DICOM images encryption in comparison with those originally embedded into DICOM advanced encryption standard...
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Properties of Thermally Dewetted Thin Au Films on ITO-Coated Glass for Biosensing Applications
PublikacjaNoble metal nanostructures are object of great interest due to their unique optical and electronic properties exploited in nanotechnology, medicine, biochemistry, and surface-enhanced spectroscopies. In this work, the Au nanoparticle (NP) structures for application in biosensing obtained by dewetting are investigated in dependence on their preparation conditions. Structures are produced from thin Au films (5–30 nm) sputtered onto...
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Zirconia ceramics with additions of Alumina for advanced tribological and biomedical applications
PublikacjaThe results of an investigation on slip cast and sintered Y2O3 (3 wt%)- stabilized ZrO2 with additions of 5, 10, 15 wt% Al2O3 are reported. The surface roughness, porosity and density of the samples were measured. The hardness HRc and Hv, fracture toughness K1C, and friction coefficients were also measured using standard methods. The structural properties of the samples were observed by Scanning Electron Microscopy (SEM). The surface...
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Metal-Organic Framework (MOF)/Epoxy Coatings: A Review
PublikacjaEpoxy coatings are developing fast in order to meet the requirements of advanced materials and systems. Progress in nanomaterial science and technology has opened a new era of engineering for tailoring the bulk and surface properties of organic coatings, e.g., adhesion to the substrate, anti-corrosion, mechanical, flame-retardant, and self-healing characteristics. Metal-organic frameworks (MOFs), a subclass of coordinative polymers...
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Determination of aminoglycoside antibiotics: current status and future trends
PublikacjaThe use of aminoglycoside antibiotics is prevalent in medicine and agriculture. Their overuse increases their mobility in the environment, resulting in a need for reliable methods for their determination in a variety of matrices. However, the properties of aminoglycosides, in particular their high polarity, make the development of such methods a non-trivial task, inciting researchers to tackle this complex issue from different...
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Selected issues related to the toxicity of ionic liquids and deep eutectic solvents—a review
PublikacjaGreen Chemistry plays a more and more important role in implementing rules of sustainable development to prevent environmental pollution caused by technological processes, while simultaneously increasing the production yield. Ionic liquids (ILs) and deep eutectic solvents (DESs) constitute a very broad group of substances. Apart from many imperfections, ILs and DESs have been the most promising discoveries in the world of Green...
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Application of 3D- printed hydrogels in wound healing and regenerative medicine
PublikacjaHydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on the use of hydrogels as bioinks for three-dimensional (3D) printing in tissue engineering. Bioprinting involves the fabrication of complex structures from several types of materials, cells,...
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The problem of infections associated with implants – an overview
PublikacjaImplant-associated infections are serious and relatively common complication that leads to implant loss. The purpose of this paper is to gather knowledge about this issue. A literature review of the epidemiology, risk factors and pathogenesis of infections related to implants was carried out. This position collects data on commonly used implants and infections associated with them from various fields of medicine and contains classifications...
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Fabrication and Characterization of Flexible Medical-Grade TPU Filament for Fused Deposition Modeling 3DP Technology
PublikacjaThe possibility of using additive manufacturing (AM) in the medicine area has created new opportunities in health care. This has contributed to a sharp increase in demand for 3D printers, their systems and materials that are adapted to strict medical requirements. We described herein a medical-grade thermoplastic polyurethane (S-TPU) which was developed and then formed into a filament for Fused Deposition Modeling (FDM) 3D printers...
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COMPOSITE MATERIAL SELECTION FOR A PATIENT TRANSFER ASSIST DEVICE
PublikacjaLaminates - layered composites containing at least two elements (matrix and reinforcement) widely used in industry have also found their usage in medicine. Their main feature is the ability to modify the material in order to obtain the required properties. Depending on the needs, we can modify reinforcement, type of resin or the method of bonding substrates. Commonly used fibers are: carbon fiber, glass and aramid fibers; resins...