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Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates
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Tolerance Optimization of Antenna Structures by Means of Response Feature Surrogates
PublikacjaFabrication tolerances and other types of uncertainties, e.g., the lack of precise knowledge of material parameters, have detrimental effects on electrical and field performance of antenna systems. In the case of input characteristics these are particularly noticeable for narrow- and multi-band antennas where deviations of geometry parameters from their nominal values lead to frequency shifts of the operating frequency bands. Improving...
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Composite sandwich footbridge - measured dynamic response vs. FEA
PublikacjaThe paper describes a process of in situ dynamic tests of a composite sandwich footbridge before its accepta-tion for exploitation in real traffic conditions. It is only a part of a big research task that includes design, manufacture and introduce practical application of the bridge. The in situ measured natural modes and fre-quencies are compared with numerically determined ones. Finite element analysis is established to estimate...
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DYNAMIC RESPONSE OF FORUM GDANSK STRUCTURE DUE TO RAIL TRAFFIC
PublikacjaThe paper presents the study of the impact of vibration induced by the movement of the railway rolling stock on the Forum Gdańsk structure. This object is currently under construction and is located over the railway tracks in the vicinity of the Gdańsk Główny and Gdańsk Śródmieście railway stations. The analysis covers the influence of vibrations on the structure itself and on the people within. The in situ measurements on existing...
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublikacjaMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Modeling and optimization of chemical-treated torrefaction of wheat straw to improve energy density by response surface methodology
PublikacjaToday, torrefaction is important technique for extending the potential of biomass for improvement of energy density. The independent variables investigated for torrefaction study were temperature, retention time, acid concentration, and particle size. The experiment was designed by central composite design (CCD) method using design expert (version 11). The three dependent variables were higher heating value (HHV), energy enhancement...
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Local and global response of sandwich beams made of GFRP facings and PET foam core in three point bending test
PublikacjaIn the paper behaviour of laminated sandwich beams (FRP face sheet – PET foam core – FRP face sheet) subjected to three point bending is studied. The paper aim is to find practical descriptions enabling effective and accurate estimation of the elastic response, damage and failure of the beams, basing on experiments and static calculations. Therefore a number of tests are described, that were done on laminated coupons and foam specimens...
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On Accelerated Metaheuristic-Based Electromagnetic-Driven Design Optimization of Antenna Structures Using Response Features
PublikacjaDevelopment of present-day antenna systems is an intricate and multi-step process requiring, among others, meticulous tuning of designable (mainly geometry) parameters. Concerning the latter, the most reliable approach is rigorous numerical optimization, which tends to be re-source-intensive in terms of computing due to involving full-wave electromagnetic (EM) simu-lations. The cost-related issues are particularly pronounced whenever...
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Electrochemically Obtained TiO2/CuxOy Nanotube Arrays Presenting a Photocatalytic Response in Processes of Pollutants Degradation and Bacteria Inactivation in Aqueous Phase
PublikacjaTiO2/CuxOy nanotube (NT) arrays were synthesized using the anodization method in the presence of ethylene glycol and different parameters applied. The presence, morphology, and chemical character of the obtained structures was characterized using a variety of methods—SEM (scanning electron microscopy), XPS (X-ray photoelectron spectroscopy), XRD (X-ray crystallography), PL (photoluminescence), and EDX (energy-dispersive X-ray spectroscopy)....
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An attempt to develop a model selection algorithm of computer simulation during the design process of mechanical response of any mechanical body
Publikacjan the literature, there are algorithms associated with the design of simulations of technological processes, in which the material model has always been defined previously. However, in none of the studies of computer simulation modelling of technological processes known to the authors of this article, is there a detailed description of how the algorithm, or the selection of plastic model used, is subject to this process. This article...
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An Attempt to Develop a Model Selection Algorithm of Computer Simulation during the Design Process of Mechanical Response of Any Mechanical Body
PublikacjaIn the literature, there are algorithms associated with the design of simulations of technological processes, in which the material model has always been defined previously. However, in none of the studies of computer simulation modelling of technological processes known to the authors of this article, is there a detailed description of how the algorithm, or the selection of plastic model used, is subject to this process. This...
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Seismic response and performance prediction of steel buckling-restrained braced frames using machine-learning methods
PublikacjaNowadays, Buckling-Restrained Brace Frames (BRBFs) have been used as lateral force-resisting systems for low-, to mid-rise buildings. Residual Interstory Drift (RID) of BRBFs plays a key role in deciding to retrofit buildings after seismic excitation; however, existing formulas have limitations and cannot effectively help civil engineers, e.g., FEMA P-58, which is a conservative estimation method. Therefore, there is a need to...
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Exploring the technological dimension of Autonomous sensory meridian response-induced physiological responses Cite this as Seifzadeh S, Kostek B. 2024. Exploring the technological dimension of Autonomous sensory meridian response-induced physiological responses. PeerJ 12:e17754 https://doi.org/10.7717/peerj.17754
PublikacjaBackground In recent years, the scientific community has been captivated by the intriguing Autonomous sensory meridian response (ASMR), a unique phenomenon characterized by tingling sensations originating from the scalp and propagating down the spine. While anecdotal evidence suggests the therapeutic potential of ASMR, the field has witnessed a surge of scientific interest, particularly through the use of neuroimaging techniques...
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Effect of sweet grass extract against oxidative stress in rat liver and serum
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Green Tea Protection Against Age-Dependent Ethanol-Induced Oxidative Stress
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Perceived stress level among patients with chronic illness during covid pandemia
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Importance of oxidative stress in the pathogenesis, diagnosis, and monitoring of patients with neuropsychiatric disorders, a review
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Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis
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Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
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Comparison of Oxidative Stress/DNA Damage in Semen and Blood of Fertile and Infertile Men
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Halotolerant fungi stimulate growth and mitigate salt stress in Alnus glutinosa Gaertn.
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Damage detection of a T-shaped panel by wave propagation analysis in the plane stress
PublikacjaW pracy zaprezentowano podejście obliczeniowe do analizy propagacji fal w płaskim stanie naprężenia. Problem brzegowo-początkowy podlega przestrzennej aproksymacji z użyciem wielowęzłowych, izoparametrycznych, czworobocznych elementów klasy C0. Macierze elementowe są całkowane numerycznie za pomocą kwadratury Gauss-Legendre-Lobatto. Aproksymację w dziedzinie czasu wykonano za pomocą algorytmu Newmarka. Symulacje numeryczne przeprowadzono...
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Long-term researches of stress corrosion cracking of Al-Zn-Mg alloys
PublikacjaPraca przedstawia wyniki odporności na korozję naprężeniową stopów Al-Zn-Mg uzyskane w warunkach stacjonarnych. Dodatkowo określono wpływ składu chemicznego oraz obróbki cieplnej na odporność korozyjną tych stopów. Badania prowadzono w 3% NaCl w warunkach stałego obciążenia σ = 0.8R0.2 przez 1500 godzin. Stwierdzono, iż zawartość Zn i Mg oraz szybkość chłodzenia to główne czynniki wpływające na podatność tych stopów na korozje...
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A proposition of the computational model for the dynamic analysis of stress and strain distribution in the hip joint
PublikacjaCelem pracy jest sformułowanie zadania modelowania dynamiki odkształceń i rozkładu naprężeń stawu biodrowego, a w szczególności kości udowej, pod wpływem sił mięśniowych oraz zadanych sił zewnętrznych. Rozwiązanie tego zadania pozwoli wyjaśnić niektóre zjawiska np. jakie ruchy kości udowej oraz jakie materiały użyte do jej alloplastyki są przyczyną urazów i poważnych uszkodzeń. Omówiono problemy związane z zastosowaniem metody...
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FE-calculations of stress distribution under prismatic and conical sandpiles within hypoplasticity.
PublikacjaW artykule przedstawiono wyniki numerycznej rozkładu naprężeń pod pryzmatycznymi i stożkowymi stosami piasku w ramach mikropolarnej hipoplastyczności. Wyniki pokazują, że rozkład naprężeń zależy od sposobu napełnienia stożku piaskiem. W niektórych przypadkach, maksymalne naprężenie nie występuje w środku stosu piasku.
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FE-calculations of stress distribution under prismatic and conical sandpiles within hypoplasticity
PublikacjaW artykule przedstawiono wyniki numerycznej rozkładu naprężeń pod pryzmatycznymi i stożkowymi stosami piasku w ramach mikropolarnej hipoplastyczności. Wyniki pokazują, że rozkład naprężeń zależy od sposobu napełnienia stożku piaskiem. W niektórych przypadkach, maksymalne naprężenie nie występuje w środku stosu piasku.
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Use of response surface methodology in characterization of properties of recycled high density polyethylene/ground tire rubber compositions
PublikacjaSearching for newways to utilize rubber and polymerwaste has been the focus of many studies conducted by research centers and companies worldwide. In this study, the influence of extrusion conditions on the properties of thermoplastic compositions containing post-production recycled high density polyethylene (PE-HD) and ground tire rubber (GTR) at 50:50 mass ratiowas examined. Response Surface Methodology (RSM) was used to determine...
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Expedited Machine-Learning-Based Global Design Optimization of Antenna Systems Using Response Features and Multi-Fidelity EM Analysis
PublikacjaThe design of antenna systems poses a significant challenge due to stringent per-formance requirements dictated by contemporary applications and the high com-putational costs associated with models, particularly full-wave electromagnetic (EM) analysis. Presently, EM simulation plays a crucial role in all design phases, encompassing topology development, parametric studies, and the final adjustment of antenna dimensions. The latter...
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Rapid Design Centering of Multi-Band Antennas Using Knowledge-Based Inverse Models and Response Features
PublikacjaAccounting for manufacturing tolerances as well as uncertainties concerning operating conditions and material parameters is one of the important yet often neglected aspects of antenna development. Appropriate quantification of uncertainties allows for estimating the fabrication yield but also to carry out robust design (e.g., yield maximization). For reliability reasons, statistical analysis should be executed at the accuracy level...
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Morphometric evaluation of the delayed cerebral arteries response to acetazolamide test in patients with chronic carotid artery stenosis using computed tomography angiography
PublikacjaBackground: The evidence accumulates that the response to acetazolamide test is delayed on the ipsilateral side to stenosis. However, the effect of acetazolamide beyond 30 minutes after acetazolamide administration remains unknown. The aim of this study was to assess the diameters of: anterior cerebral arteries (ACAs), middle cerebral arteries (MCAs) and posterior cerebral arteries (PCAs) before and 60 minutes after the acetazolamide...
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THE ANALYSIS OF THE INFLUENCE OF STRESS DISTRIBUTION ON WEAR PROFILE IN LUBRICATED SLIDING CONTACT OF UHMW-PE VS TITANIUM Ti-13Nb-13Zr ALLOY
PublikacjaMetal – polymer sliding contacts are a typical combination in industry and medicine. For decades such a set of materials has been the primary choice in human joints endoprosthetic technology. In this paper tribological issues of are presented from a research on the potential for practical use of Ti-13Nb-13Zr/UHMW-PE couple for orthopedic endoprosthesis. In tests on simplified models it is critically important to carefully...
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Low-Cost Quasi-Global Optimization of Expensive Electromagnetic Simulation Models by Inverse Surrogates and Response Features
PublikacjaConceptual design of contemporary high-frequency structures is typically followed by a careful tuning of their parameters, predominantly the geometry ones. The process aims at improving the relevant performance figures, and may be quite expensive. The reason is that conventional design methods, e.g., based on analytical or equivalent network models, often only yield rough initial designs. This is especially the case for miniaturized...
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Seismic Response Analysis of Knee-Braced Steel Frames Using Ni-Ti Shape Memory Alloys (SMAs)
PublikacjaShape Memory Alloys (SMAs) are known as active materials that can be widely used for structural purposes due to their flag-shape behavior under loading and reloading. Their unique characteristics provided a potential solution for civil engi-neers especially to model buildings with the capability of dissipating seismic en-ergy. In this study, the main purpose is to explore the seismic behavior of Knee-Braced Frames (KBFs) and...
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CYP3A4-dependent cellular response does not relate to CYP3A4-catalysed metabolites of C-1748 and C-1305 acridine antitumor agents in HepG2 cells
PublikacjaHigh CYP3A4 expression sensitizes tumor cells to certain antitumor agents while for others it can lower their therapeutic ef fi cacy. We have elucidated the in fl uence of CYP3A4 overexpression on the cellular response induced by antitumor acridine derivatives, C-1305 and C-1748, in two hepatocellular carcinoma (HepG2) cell lines, Hep3A4 stably transfected with CYP3A4 isoenzyme, and HepC34 expressing empty vector. The compounds...
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Effect of Axial Porosities on Flexomagnetic Response of In-Plane Compressed Piezomagnetic Nanobeams
PublikacjaWe investigated the stability of an axially loaded Euler–Bernoulli porous nanobeam considering the flexomagnetic material properties. The flexomagneticity relates to the magnetization with strain gradients. Here we assume both piezomagnetic and flexomagnetic phenomena are coupled simultaneously with elastic relations in an inverse magnetization. Similar to flexoelectricity, the flexomagneticity is a size-dependent property. Therefore,...
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Standard hypothyroid treatment did not restore proper metabolic response to carbohydrate
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The application of response surface method to optimization of precision ball end milling
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Acute hypertensive response in ischemic stroke is associated with increased aortic stiffness
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Response Surface Methodology Application for Bacteriophage–Antibiotic Antibiofilm Activity Optimization
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The use of response surface methodology for reliability estimation of composite engineering structures
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Cortical Activation Changes Associated with Autonomous Sensory Meridian Response (ASMR)
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THE COVID-19 DISEASE AND POLICY RESPONSE TO MITIGATE THE ECONOMIC IMPACT IN THE EU
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Study on the Effect of Rotating Magnetic Field on Cellular Response of Mammalian Cells
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TRAVELLING WAVES FOR LOW–GRADE GLIOMA GROWTH AND RESPONSE TO A CHEMOTHERAPY MODEL
PublikacjaLow-grade gliomas (LGGs) are primary brain tumours which evolve very slowly in time, but inevitably cause patient death. In this paper, we consider a PDE version of the previously proposed ODE model that describes the changes in the densities of functionally alive LGGs cells and cells that are irreversibly damaged by chemotherapy treatment. Besides the basic mathematical properties of the model, we study the possibility of the...
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Response of a steel tank during earthquakes and mining tremors - experimental investigation
PublikacjaCylindrical steel tanks are very popular shell structures used to store the products of chemical and petroleum industries. Any failure might have disastrous consequences, therefore their safety and reliability is essential. Earthquakes are the most dangerous and also the most unpredictable dynamic loads acting on such structures. On the other hand, mining tremors are usually considered to be less severe due to lower acceleration...
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Analysis of the torque response of a car engine to the step change of the control signal
PublikacjaW pracy zamieszczono wyniki badań silnika samochodu osobowego w warunkach nieustalonych. Stan obciążenia silnika wynikał z realizowanego cyklu jezdnego w warunkach drogowych oraz sposobu sterowania układem napędowym. Parametry trakcyjne pojazdu mierzone były za pomocą systemu GPS z fenomenologiczną korektą sygnału wysokości, na której się on znajdował. Wybrane parametry pracy silnika mierzone były za pomocą sytemu komunikującego...
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On the influence of shell element properties on the response of car model in crash test
PublikacjaIt goes without saying that numerical simulations play important role in the modern engineering practice. Contemporary CAD environments combined with FEM solvers, along with computer power of modern processors, give the engineer fast and efficient tool. Ultimately, however it is the user alone who is responsible for the correctness of the results. As long as the FEM calculations remain in the sphere of academic exercise, the inevitable...
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On Memory-Based Precise Calibration of Cost-Efficient NO2 Sensor Using Artificial Intelligence and Global Response Correction
PublikacjaNitrogen dioxide (NO2) is a prevalent air pollutant, particularly abundant in densely populated urban regions. Given its harmful impact on health and the environment, precise real-time monitoring of NO2 concentration is crucial, particularly for devising and executing risk mitigation strategies. However, achieving precise measurements of NO2 is challenging due to the need for expensive and cumbersome equipment. This has spurred...
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Multi-response optimization on the effect of wet and eco-friendly cryogenic turning of D2 steel using Taguchi-based grey relational analysis
PublikacjaMaterial removal processes, including turning and milling, are still commonly used operations for manufacturing most of mechanical components in modern industry. Apart from the cutting parameters, the cooling method has the great impact on the technological efects and, above all, on the environmental friendliness of production. In this study, multi-response optimization on the efect of wet and cryogenic machining is performed during...
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Global EM-Driven Optimization of Multi-Band Antennas Using Knowledge-Based Inverse Response-Feature Surrogates
PublikacjaElectromagnetic simulation tools have been playing an increasing role in the design of contemporary antenna structures. The employment of electromagnetic analysis ensures reliability of evaluating antenna characteristics but also incurs considerable computational expenses whenever massive simulations are involved (e.g., parametric optimization, uncertainty quantification). This high cost is the most serious bottleneck of simulation-driven...