Filtry
wszystkich: 3168
wybranych: 2683
-
Katalog
- Publikacje 2683 wyników po odfiltrowaniu
- Czasopisma 149 wyników po odfiltrowaniu
- Konferencje 7 wyników po odfiltrowaniu
- Osoby 58 wyników po odfiltrowaniu
- Wynalazki 1 wyników po odfiltrowaniu
- Projekty 4 wyników po odfiltrowaniu
- Laboratoria 1 wyników po odfiltrowaniu
- Kursy Online 45 wyników po odfiltrowaniu
- Wydarzenia 7 wyników po odfiltrowaniu
- Dane Badawcze 213 wyników po odfiltrowaniu
Filtry wybranego katalogu
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: GENETIC OPERATOR
-
BCR expression is decreased in meningiomas showing loss of heterozygosity of 22q within a new minimal deletion region
Publikacja -
Highly thermostable RadA protein from the archaeon Pyrococcus woesei enhances specificity of simplex and multiplex PCR assays
Publikacja -
Modified DNA polymerases for PCR troubleshooting
PublikacjaPCR has become an essential tool in biological science. However, researchers often encounter problems with difficult targets, inhibitors accompanying the samples, or PCR trouble related to DNA polymerase. Therefore, PCR optimization is necessary to obtain better results. One solution is using modified DNA polymerases with desirable properties for the experiments. In this article, PCR troubleshooting, depending on the DNA polymerase...
-
Genistein: a lysosomal stimulator for treatment of various lysosomal diseases
Publikacja -
The molecular mechanism of genistein action in lysosomal storage diseases: A transcriptomic approach
Publikacja -
Wnt pathway antagonists, SFRP1, SFRP2, SOX17, and PPP2R2B, are methylated in gliomas and SFRP1 methylation predicts shorter survival
Publikacja -
Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients
Publikacja -
Recurrent bowel-blood translocations of Escherichia coli with the unique virulence characteristics over three-year period in the patient with acute myeloid leukaemia – case report
PublikacjaIn patients with haematological malignancies, the bowel remains the main source of Escherichia coli bloodstream infections. We present the clinical example of recurrent bowel-blood translocations of E. coli with the unique virulence characteristics in a 55-year-old male with the diagnosis of acute myeloid leukaemia. The virulent factors profile of examined strains confirmed that the co-existence of genes papC, sfa, usp and cnf1,...
-
A new assay based on terminal restriction fragment length polymorphism of homocitrate synthase gene fragments for Candida species identification
PublikacjaCandida sp. have been responsible for an increasing number of infections, especially in patients with immunodeficiency. Species specific differentiation of the Candida sp. is difficult in routine diagnosis. This identification can have a highly significant association in therapy and prophylaxis. This work has shown a new application of terminal restriction fragment length polymorphism (t-RFLP) method in molecular identification...
-
The metagenomic approach to characterization of the microbial community shift during the long-term cultivation of anammox-enriched granular sludge
PublikacjaA metagenomic approach was used to investigate how the microbial community composition changes when an anammox-based granular sludge reactor is seeded with nitritation-anammox biomass from a wastewater treatment plant. In the seed sample, the abundance of Candidatus Kuenenia stuttgartiensis was similar to Candidatus Jettenia caeni (12.63 vs. 11.68%). This biomass was typical in terms of microbial nitrogen conversion; both ammonia...
-
Versatility of putative aromatic aminotransferases from Candida albicans.
PublikacjaAmino acids constitute the key sources of nitrogen for growth of Candida albicans. In order to survive inside the host in different and rapidly changing environments, this fungus must be able to adapt via its expression of genes for amino acid metabolism. We analysed the ARO8, ARO9, YER152C, and BNA3 genes with regards to their role in the nutritional flexibility of C. albicans. CaAro8p is undoubtedly the most versatile enzyme...
-
Discrimination of hospital isolates of Acinetobacter baumannii using repeated sequences and whole genome alignment differential analysis
PublikacjaAn optimized method for bacterial strain differentiation, based on combination of Repeated Sequences and Whole Genome Alignment Differential Analysis (RS&WGADA), is presented in this report. In this analysis, 51 Acinetobacter baumannii multidrug-resistance strains from one hospital environment and patients from 14 hospital wards were classified on the basis of polymorphisms of repeated sequences located in CRISPR region, variation...
-
Angiotensin converting enzyme gene polymorphism is associated with severity of coronary artery disease in men with high total cholesterol levels
Publikacja -
The Reduced Folate Carrier (SLC19A1) c.80G>A Polymorphism is Associated with Red Cell Folate Concentrations Among Women
Publikacja -
Evidence for sex differences in the determinants of homocysteine concentrations
Publikacja -
Retained features of embryonic metabolism in the adult MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain that was derived by selective breeding in 1960 from the rapidly growing LG/J (Large) strain. MRL mice grow to nearly twice the size of other commonly used mouse strains, display uncommonly robust healing and regeneration properties, and express later onset autoimmune traits similar to Systemic Lupus Erythematosis. The regeneration trait (heal) in the MRL mouse maps to 14-20 quantitative...
-
A simple modification of PCR thermal profile applied to evade persisting contamination
PublikacjaThe polymerase chain reaction (PCR), one of the most commonly applied methods of diagnostics and molecular biology has a frustrating downside known as the false positive signal or contamination. Several solutions to avoid and to eliminate PCR contaminations have been worked out to date but the implementation of these solutions to laboratory practice may be laborious and time consuming. A simple approach to circumvent the problem...
-
New Method for Determination of Adjustment Corrections for Crane Rail Axes
PublikacjaElectronic tacheometers are currently a standard instrument used in geodetic work, including also geodetic engineering measurements. One of the many applications of tacheometers in engineering geodesy are 3D control measurements of crane rail axes. This paper proposes a new method of computing adjustment corrections for crane rail axes based on 3D polar measurements performed with an electronic tacheometer. The intermediary method...
-
Optymalizacja strategii sieci inteligentnych agentów za pomocą programowania genetycznego w systemie rozproszonym realizującym paradygmat volunteer computing
PublikacjaDynamicznie rosnąca złożoność i wymagania w odniesieniu do rozproszonych systemów informatycznych utrudnia zarządzanie dostępnymi zasobami sprzętowymi i programistycznymi. Z tego powodu celem rozprawy jest opracowanie wielokryterialnej metody programowania genetycznego, która pozwala na optymalizację strategii zespołu inteligentnych agentów programistycznych w zakresie zarządzania systemem realizującym paradygmat volunteer computing....
-
Accurate modeling of layout parasitic to forecast EMI emitted from a DC-DC converter.
PublikacjaThis paper illustrates how to account for all parasitic due to the layout of a power converter (inductive and capacitive), in order to forecast electromagnetic interferences (EMI). The method is generic, and is validated here in the simple example of a DC-DC converter, realized on different technologies: insulated metal substrate (IMS), printed circuit board (PCB). In addition, several layouts aspects will be investigated. Conclusions...
-
A New Approach to Stability Evaluation of Digital Filters
PublikacjaIn this paper, a new numerical method of evaluating digital filter stability is presented. This approach is based on novel root-finding algorithms at the complex plane using the Delaunay triangulation and Cauchy's Argument Principle. The presented algorithm locates unstable zeros of the characteristic equation with their multiplicities. The proposed method is generic and can be applied to a vast range of systems. Verification of...
-
Enzymes of the lysine biosynthetic pathway as targets for antifungals ?
PublikacjaSystemic infections caused by human pathogenic fungi in immunocompromized patients continue to be one of the important clinical problems. Limited availability of safe and efficacious antifungal chemotherapeutics and emerging resistance to existing drugs stimulates search for novel molecular targets for antifungals. The α-aminoadipate pathway (AAP) of L-lysine biosynthesis is unique in fungi and thus has been so far considered...
-
Dead time effects compensation strategy by third harmonic injection for a five-phase inverter
PublikacjaThis paper proposes a method for compensation of dead-time effects for a fivephase inverter. In the proposed method an additional control subsystem was added to the field-oriented control (FOC) scheme in the coordinate system mapped to the third harmonic. The additional control loop operates in the fixed, orthogonal reference frame ( α - β coordinates) without the need for additional Park transformations. The purpose of this method...
-
Revision of Biological Methods for Determination of EDC Presence and Their Endocrine Potential
PublikacjaEndocrine-disrupting compounds (EDC) are chemicals responsible for disturbances in the hormonal balance of organisms. This group of chemicals includes both egzogenic and endogenic substances or their mixtures that impact functioning of natural hormones in organisms. In the available literature one can find information on the application of chromatographic and related techniques in the analysis of environmental samples for detection,...
-
Kinetics of nitrogen removal processes in constructed wetlands
PublikacjaThe aim of this paper is to present a state-of-the-art review of the kinetics of nitrogen removal in constructed wetlands. Biological processes of nitrogen removal from wastewater can be described using equations and kinetic models. Hence, these kinetic models which have been developed and evaluated allow for predicting the removal of nitrogen in treatment wetlands. One of the most important, first order removal model, which is...
-
Inverse Modeling and Optimization of CSRR-based Microwave Sensors for Industrial Applications
PublikacjaDesign optimization of multivariable resonators is a challenging topic in the area of microwave sensors for industrial applications. This paper proposes a novel methodology for rapid re-design and parameter tuning of complementary split-ring resonators (CSRRs). Our approach involves inverse surrogate models established using pre-optimized resonator data as well as analytical correction techniques to enable rapid adjustment of geometry...
-
INVESTIGATION OF THE CHARACTERISTICS OF A LOWEMISSION GAS TURBINE COMBUSTION CHAMBER OPERATING ON A MIXTURE OF NATURAL GAS AND HYDROGEN
PublikacjaT his article is devoted to the investigation of the characteristics of a low-emission gas turbine combustion chamber, which can be used in Floating Production, Storage and Offloading (FPSO) vessels and operates on a mixture of natural gas and hydrogen. A new approach is proposed for modelling the processes of burning out a mixture of natural gas with hydrogen under preliminary mixing conditions in gaseous fuel with an oxidizer...
-
Recurrent Neural Network Based Adaptive Variable-Order Fractional PID Controller for Small Modular Reactor Thermal Power Control
PublikacjaThis paper presents the synthesis of an adaptive PID type controller in which the variable-order fractional operators are used. Due to the implementation difficulties of fractional order operators, both with a fixed and variable order, on digital control platforms caused by the requirement of infinite memory resources, the fractional operators that are part of the discussed controller were approximated by recurrent neural networks...
-
EASY ACCESS TOOL FOR SMALL INTERFERING RNA (siRNA) DATA
PublikacjaFor many decades it was an accepted dogma of molecular genetics that the expression of genes is a “one-way-road” leading only in one direction from DNA to RNA to proteins. Recent discoveries in modern molecular genetics have challenged this dogma showing that specific RNA molecules play a central role in controlling the activity of genes by changing the structure of DNA sequences, targeting other RNAs for degradation or blocking...
-
VARIANT DESIGNING IN the PRELIMINARY SMALL SHIP DESIGN PROCESS
PublikacjaShip designing is a complex process, as the ship itself is a complex, technical multi-level object which operates in the air/water boundary environment and is exposed to the action of many different external and internal factors resulting from the adopted technical solutions, type of operation, and environmental conditions. A traditional ship design process consists of a series of subsequent multistage iterations, which gradually...
-
Zabezpieczenia antykorozyjne stalowych barierek ochronnych na obiektach mostowych w ujęciu kosztów cyklu ich życia
PublikacjaThe article presents the Life Cycle Costs analysis of steel safety barriers operated in road lane conditions, located on a selected bridge structure. Three corrosion protection systems were proposed, analyzing them in terms of the cost of initial and planned outlays related to maintenance. Based on the LCC analysis for three options, taking into account the 25-year lifetime of the barriers, the optimal solutionwas indicated, i.e....
-
Bezpieczeństwo funkcjonalne i norma IEC 61508.
PublikacjaArtykuł poświęcono genezie serii norm IEC 61508 i wprowadzeniu do koncepcji bezpieczeństwa funkcjonalnego z uwzględnieniem podstawowego przewodnika, wydanego ostatnio przez IEC (International Electrotechnical Commission.
-
Tripping of F-type RCDs for sinusoidal residual current with superimposed smooth DC component
PublikacjaRecent trends in green energy development make that photovoltaics and electric vehicles are applied on an increasing scale. In both photovoltaic and electric vehicle charging installations, a significant value of DC component of the earth fault current may appear, which is a challenge, in particular, for commonly used residual current devices (RCDs). This paper presents results of the laboratory test on the operation of F-type...
-
Metaheurystyki sztucznej inteligencji w wybranych grach komputerowych
PublikacjaW pracy omówiono trzy metaheurystyki sztucznej inteligencji, które mogą stać się źródłem inspiracji dla projektantów gier komputerowych. Pokazano, w jaki sposób zastosowano algorytm mrówkowy, algorytm genetyczny i algorytm tabu search w grach komputerowych zaprojektowanych przez studentów Politechniki Gdańskiej. W szczególności, odniesiono się do problematyki wyznaczania trajektorii przemieszczających się obiektów...
-
Design of a Shape-Memory-Alloy-Based Carangiform Robotic Fishtail with Improved Forward Thrust
PublikacjaShape memory alloys (SMAs) have become the most common choice for the development of mini- and micro-type soft bio-inspired robots due to their high power-to-weight ratio, ability to be installed and operated in limited space, silent and vibration-free operation, biocompatibility, and corrosion resistance properties. Moreover, SMA spring-type actuators are used for developing different continuum robots, exhibiting high degrees...
-
Biofilm Production and Presence of ica and bap Genes in Staphylococcus aureus Strains Isolated from Cows with Mastitis in the Eastern Poland
PublikacjaThe aim of the study was phenotypic and genotypic analysis of 132 S. aureus strains isolated from mastitis in eastern Poland in respect to their biofilm formation ability. The analysis of the size polymorphism of fragment X in the gene encoding protein A (spa) revealed high genetic differentiation of the analyzed group of isolates. The ability of biofilm formation by the isolates was tested using two phenotypic methods. The Congo...
-
Smart innovation process enhancement using SOEKS and decisional DNA
PublikacjaProduct innovation always requires a foundation based on both knowledge and experience. The production and innovation process of products is very similar to the evolution process of humans. The genetic information of humans is stored in genes, chromosomes and DNA. Similarly, the information about the products can be stored in a system having virtual genes, chromosomes and decisional DNA (DDNA). The present paper proposes...
-
Framework for Product Innovation Using SOEKS and Decisional DNA
PublikacjaProduct innovation always requires a foundation based on both knowledge and experience. The production and innovation process of products is very similar to the evolution process of humans. The genetic information of humans is stored in genes, chromosomes and DNA. Similarly, the information about the products can be stored in a system having virtual genes, chromosomes and decisional DNA. The present paper proposes a framework for...
-
Sensor Position Estimation Method for IoT Using Mobile Reference Node
PublikacjaThe paper proposes an innovative method of locating objects for the Internet of Things (IoT). The proposed method allows the position of a fixed measuring sensor (MS) to be estimated using one mobile base station with a known position moving around the MS. The mathematical analysis of the method, and three algorithms — Newton’s (NA), gradient descent (GD) and genetic (GA) — for solving the system of non-linear positional equations...
-
Power efficient thrust allocation algorithms in design of dynamically positioned ships
PublikacjaAssessment of power consumption on a Dynamically Positioned (DP) ship in the early design stage can assist crucial design choices. The study presents a comparison between two algorithms of optimal thrust allocation in a propulsion system for an over-actuated DP ship. Applied algorithms were Quadratic Programming (QP) and Non- dominated Sorting Genetic Algorithm II (NSGAII). Based on both approaches, tools were developed for ship...
-
Comparison of Two Nonlinear Predictive Control Algorithms for Dissolved Oxygen Tracking Problem at WWTP
PublikacjaThe wastewater treatment plant is classified as a complex system, due to its nonlinear dynamics, large uncertainty of disturbance inputs, multiple time scales in the internal process dynamics, and multivariable structure. The aeration process, in turn, is an important and expensive part of wastewater treatment plant operation. All operating parameters of the aeration in biological processes are to be precisely controlled to provide...
-
Study on transmission quality in cellular 4G and 5G networks between 2019–2021: Impact of the COVID-19 pandemic on the level of provided services by operating base transceiver stations
PublikacjaThe COVID-19 pandemic has significantly limited user mobility, not least among students. Remote learning had a particular impact on resource allocation in relation to using terrestrial cellular networks, especially 4G systems in urban agglomerations. This paper presents the results of a quality evaluation of an outdoor environment, carried out between 2019 and 2021 on the campus of a technical university. Annual studies are conducted...
-
Broker telekomunikacyjny
PublikacjaDemonopolizacja rynku usług telekomunikacyjnych narzuca konieczność realizacji funkcji wyboru operatora sieci dla obsługi żądania usługi. W pracy przedstawiono koncepcję, realizację oraz wyniki testów i badań Brokera Telekomunikacyjnego BT, który realizuje tą funkcję. Algorytm podejmowania decyzji przez BT uwzględnia parametry poziomu i jakości usług oferowane przez operatorów oraz preferencje klienta dotyczące połączenia. Klient...
-
Study on CPU and RAM Resource Consumption of Mobile Devices using Streaming Services
PublikacjaStreaming multimedia services have become very popular in recent years, due to the development of wireless networks. With the growing number of mobile devices worldwide, service providers offer dedicated applications that allow to deliver on-demand audio and video content anytime and everywhere. The aim of this study was to compare different streaming services and investigate their impact on the CPU and RAM resources, with respect...
-
The Maslov index and the spectral flow—revisited
PublikacjaWe give an elementary proof of a celebrated theorem of Cappell, Lee and Miller which relates the Maslov index of a pair of paths of Lagrangian subspaces to the spectral flow of an associated path of self-adjoint first-order operators. We particularly pay attention to the continuity of the latter path of operators, where we consider the gap-metric on the set of all closed operators on a Hilbert space. Finally, we obtain from Cappell,...
-
Generalized Dobrushin Coefficients on Banach Spaces
PublikacjaThe asymptotic behavior of iterates of bounded linear operators (not necessarily positive), acting on Banach spaces, is studied. Through the Dobrushin ergodicity coefficient, we generalize some ergodic theorems obtained earlier for classical Markov semigroups acting on L1 (or positive operators on abstract state spaces).
-
Multi-state multi-reference Møller-Plesset second-order perturbation theory for molecular calculations
PublikacjaThis work presents multi‐state multi‐reference Møller–Plesset second‐order perturbation theory as a variant of multi‐reference perturbation theory to treat electron correlation in molecules. An effective Hamiltonian is constructed from the first‐order wave operator to treat several strongly interacting electronic states simultaneously. The wave operator is obtained by solving the generalized Bloch equation within the first‐order...
-
Numerical and quantitative analysis of HIV/AIDS model with modified Atangana-Baleanu in Caputo sense derivative
PublikacjaFractional calculus plays an important role in the development of control strategies, the study of the dynamical transmission of diseases, and some other real-life problems nowadays. The time-fractional HIV/AIDS model is examined using a novel method in this paper. Based on the Atangana-concept Baleanu’s of a derivative in the Caputo sense, the current modified fractional derivative operator uses singular and non-local kernels....
-
Testing Stability of Digital Filters Using Optimization Methods with Phase Analysis
PublikacjaIn this paper, novel methods for the evaluation of digital-filter stability are investigated. The methods are based on phase analysis of a complex function in the characteristic equation of a digital filter. It allows for evaluating stability when a characteristic equation is not based on a polynomial. The operation of these methods relies on sampling the unit circle on the complex plane and extracting the phase quadrant of a function...
-
Method of evaluation of lubricating ability of lube oils and fuels in energetistic formulation
PublikacjaThe paper presents an interpretation of operation of a boundary layer of a lubricating medium. A model of the homogeneous Poisson process has been proposed to assess the deterioration process of the layer's operation. The assessment considers the original interpretation of operation of a boundary layer, as a lubricity measure of a boundary layer of any lubricant. In the submitted proposal the operation of a boundary layer is understood...