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Wyniki wyszukiwania dla: COPPER PEPTIDES
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The kinetics of substitution reaction of oxydiacetate and thiodiacetate copper(II) complexes with 1,10-phenanthroline and 2,2’-bipyridine
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Spider Webs and Lichens as Bioindicators of Heavy Metals: A Comparison Study in the Vicinity of a Copper Smelter (Poland)
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Enhanced visible light-activated gas sensing properties of nanoporous copper oxide thin films
PublikacjaMetal oxide gas sensors are popular chemoresistive sensors. They are used for numerous tasks, including environmental and safety monitoring. Some gas-sensing materials exhibit photo-induced properties that can be utilized for enhanced gas detection by modifying the sensor selectivity and sensitivity when illuminated by light. Here, we present the gas sensing characteristics of highly nanoporous Cu2O thin films towards both electrophilic...
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The Influence of the Chemical Composition of Selected Waste Materials from the Production of Copper on the Final Environmental Assessment
PublikacjaThis article presents qualitative and quantitative analysis of the waste produced by KGHM Polska Miedź. The waste has been analyzed according to its chemical composition and balanced in order to be reused and recycled. Special attention has been paid to mining industries producing the biggest amount of waste and ore enrichment businesses generating waste, which isn’t reused nowadays. Laboratory reseach has been conducted on floatation...
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Assessment of copper surface coverage with corrosion inhibitor using AFM-based local electrical measurements
PublikacjaThe paper presents a new method of assessment of metal surface coverage with corrosion inhibitor and thus of inhibitor protective performance. It is based on the atomic force microscopy measurement performed in a contact mode. Apart from topography images the proposed approach allows acquisition of local DC maps and local electrical impedance spectra via application of DC bias voltage or AC perturbation signal between the conductive...
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Copper(II) complexes with Fusobacterium nucleatum adhesin FadA: Coordination pattern, physicochemical properties and reactivity
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
PublikacjaSelf-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless wound healing. To overcome repeated administration of peptides which accelerate healing, we report development of three new peptide biomaterials based on the RADA16-I hydrogel functionalized with a sequence (AAPV) cleaved by human neutrophil elastase...
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Tissue fixed with formalin and processed without paraffin embedding is suitable for imaging of both peptides and lipids by MALDI-IMS
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Taste-active peptides and amino acids of pork meat as components of dry-cured meat products: An in-silico study
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POWER EFFICIENCY OF POWER PLANTS ON TRAILING SUCTION HOPPER DREDGERS
PublikacjaThis paper presents the notion of operational power efficiency and compares it with the classical definition of power efficiency. There are presented also calculation results of power efficiency for a selected suction hopper dredger and also influence of power system type of suction hopper dredger on magnitude of power efficiency of its power plant has been highlighted.
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Demand determination for electrical energy for trailing suction hopper dredgers
PublikacjaPrzedstawiono metodę określania obciążeń elektrowni w typowych stanach eksploatacji pogłębiarki ssącej nasiębiernej. Przedstawiono sposób określania średniego zapotrzebowania energii elektrycznej i jego odchylenia standardowego. Wykorzystano dane dokumentacji projektowych 10 pogłębiarek ssących nasiębiernych oraz wyniki badań eksploatacyjnych pogłębiarek zawarte w bazie danych DRAGA.
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Imunofan - RDKVYR peptide - stimulates skin cell proliferation and promotes tissue repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today's science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical...
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Rapid PD-L1 detection in tumors with PET using a highly specific peptide
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Hydrazone Linker as a Useful Tool for Preparing Chimeric Peptide/Nonpeptide Bifunctional Compounds
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Imunofan—RDKVYR Peptide—Stimulates Skin Cell Proliferation and Promotes Tissue Repair
PublikacjaRegeneration and wound healing are vital to tissue homeostasis and organism survival. One of the biggest challenges of today’s science and medicine is finding methods and factors to stimulate these processes in the human body. Effective solutions to promote regenerative responses will accelerate advances in tissue engineering, regenerative medicine, transplantology, and a number of other clinical specialties. In this study, we...
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The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
PublikacjaAcridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine conjugate of an imidazoacridinone derivative (Compound 1-R8) synthetized by us exhibited high antifungal activity against reference...
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A Novel Cryptic Clostridial Peptide That Kills Bacteria by a Cell Membrane Permeabilization Mechanism
PublikacjaThis work reports detailed characteristics of the antimicrobial peptide Intestinalin (P30), which is derived from the LysC enzyme of Clostridium intestinale strain URNW. The peptide shows a broader antibacterial spectrum than the parental enzyme, showing potent antimicrobial activity against clinical strains of Gram-positive staphylococci and Gram-negative pathogens and causing between 3.04 ± 0.12 log kill for Pseudomonas aeruginosa...
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Biological activity of conjugates of muramyl dipeptides with batracylin derivatives
PublikacjaZaprezentowano immunomodulacyjne właściwości nowych koniugatów batracyliny (BAT) z pochodnymi muramylodipeptydów wobec subpopulacji leukocytów krwi obwodowej hodowanych w obecności komórek linii nowotworowych. Leukocyty izolowane były z krwi obwodowej uzyskanej od zdrowych ochotników. Zbadane koniugaty MDP lub nor-MDP z batracyliną wykazały silniejsze własności hamujące proliferację komórek wybranych linii nowotworowych (K562,...
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Biological activity of conjugates of muramyl dipeptides with batracylin derivatives
PublikacjaW artykule opisano aktywność biologiczną koniugatów muramylo-dipeptydów z batracyliną lub pochodnymi batracyliny. Badania przeprowadzone w Akademii Medycznej w Gdańsku miały na celu oznaczenie immunomodulacyjnych właściwości tych koniugatów wobec subpopulacji leukocytów krwi obwodowej hodowanych w obecności komórek nowotworowych (K562, WEHI164, Ab melanoma). Leukocyty izolowane były z krwi obwodowej uzyskanej od zdrowych ochotników....
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Cyclic Peptidic Furin Inhibitors Developed by Combinatorial Chemistry
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Data regarding a new, vector-enzymatic DNA fragment amplification-expression technology for the construction of artificial, concatemeric DNA, RNA and proteins, as well as biological effects of selected polypeptides obtained using this method
PublikacjaApplications of bioactive peptides and polypeptides are emerging in areas such as drug development and drug delivery systems. These compounds are bioactive, biocompatible and represent a wide range of chemical properties, enabling further adjustments of obtained biomaterials. However, delivering large quantities of peptide derivatives is still challenging. Several methods have been developed for the production of concatemers –...
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Effect of buffer layers on performance of organic photovoltaic devices based on copper phthalocyanine-perylene dye heterojunction
PublikacjaPraca przedstawia wyniki badań układu fotowoltaicznego złożonego z cienkich warstw organicznych tworzących złącze (CuPc i MePTCDI), elektrod (ITO i Ag) oraz z warstw buforowych (MoO3 przy ITO i BCP przy Ag).
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The chemistry and toxicity of discharge waters from copper mine tailing impoundment in the valley of the Apuseni Mountains in Romania
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In-situ synthesis and characterization of biocompatible magnetic ginger nanofiber composites for copper (II) removal from water
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Buffer contribution to formation enthalpy of copper(II)–bicine complex determined by isothermal titration calorimetry method
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Experimental and theoretical analyses of the nonlinear optical effects in magnesium and copper co-doped zinc oxide nanorods
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Physicochemical Properties and Application of Silica-Doped Biochar Composites as Efficient Sorbents of Copper from Tap Water
PublikacjaThis article concerns research on new sorption materials based on silica-doped activated carbon. A two-stage synthesis involved pyrolysis of plant material impregnated in a water glass solution , followed by hydrothermal activation of the pyrolysate in KOH solution. The resulting composite can be used as a sorbent in drinking water filters. The proposed method of synthesis enables the design of materials with a surface area...
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Hollow carbon spheres loaded with uniform dispersion of copper oxide nanoparticles for anode in lithium- ion batteries
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Efficiency and kinetices of coupled transport of copper Ions Through Liquid Membranes Containing Technical Hydroxyoxime Carries
PublikacjaBadano wpływ różnych parametrów (składu faz wodnych, stężenia przenosnika, rozpuszczalnika organicznego na kinektykę i wydajność transportu jonów miedzi. Dużą wydajność procesu mozna otrzymać uzywając około 10 x mniejszego stężenia przenosanika w n-oktanie niż w przypadku innych rozpuszczalników technicznych.
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Laser induced formation of copper species over TiO2 nanotubes towards enhanced water splitting performance
PublikacjaWe proposed fast and scalable route where the ordered TiO2 nanotubes coated with thin copper layers were annealed by the laser beam of 355 nm wavelength at different fluencies in the range of 15–120 mJ/cm2. As a result, copper species are integrated with the titania substrate and the formed material exhibits unique optical absorption bands in the visible range. Moreover, X-ray photoelectron spectroscopy analysis reveals the formation...
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Rotational molding of polylactide (PLA) composites filled with copper slag as a waste filler from metallurgical industry
PublikacjaThe research work carried out so far indicates the ever wider possibilities and demand for shaping composite products in the rotational molding technology. This trend was the main reason to use waste-based filler from the metallurgical process as a filler for manufacturing polylactide (PLA)-based remolded composites. Copper slag (CS) was introduced in the single-step processing method to PLA matrix at 5, 10, 20, and 35 wt%. The...
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Analysis of chemical composition and hardness of copper alloys = Badania składu chemicznego oraz twardości stopów miedzi
PublikacjaWykonano analizę składu chemicznego oraz badania twardości stopów miedzi zastosowanych na elementy łożyskowe. Sformułowano wnioski.
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Effect of Converting Enzyme Inhibitor on Copper and Iron Concentrations of Blood Plasma in Calves During the Neonatal Period
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Activity of antimicrobial peptides and conventional antibiotics against superantigen positive Staphylococcus aureus isolated from patients with atopic dermatitis
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Potential DPP IV Inhibitory Peptides from Dry-Cured Pork Loins after Hydrolysis: An In Vitro and In Silico Study
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The psychrotrophic yeast Sporobolomyces roseus LOCK 1119 as a source of a highly active aspartic protease for the in vitro production of antioxidant peptides
PublikacjaA psychrotrophic yeast strain producing a cold-adapted protease at low temperature was classified as Sporobolomyces roseus. In standard YPG medium, S. roseus LOCK 1119 synthesized an extracellular protease with an activity of approximately 560 U/L. Optimization of medium composition and process temperature considerably enhanced enzyme biosynthesis; an approximate 70% increase in activity (2060 U/L). The native enzyme was purified...
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MRM–MS of marker peptides and their abundance as a tool for authentication of meat species and meat cuts in single-cut meat products
PublikacjaThe abundance of protein markers in different types of meat cuts was explored in the context of authentication of raw meat (pork, beef and chicken) and processed meat products. Peptides originating from myoglobin (Mb) and myosin (My) were analyzed using multiple reaction monitoring mass spectrometry (MRM–MS). Analytical protocol was optimized for good repeatability (CV < 10%) and high sensitivity. The MS signal intensity of Mb...
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Characteristics of hybrid chitosan/phospholipid-sterol, peptide coatings on plasma activated PEEK polymer
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Prediction of Peptide Retention at Different HPLC Conditions from Multiple Linear Regression Models
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Investigation ofcis/trans ratios of peptide bonds in AVP analogues containingN-methylphenylalanine enantiomers
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Evaluation of Linkers’ Influence on Peptide-Based Piezoelectric Biosensors’ Sensitivity to Aldehydes in the Gas Phase
PublikacjaRecent findings qualified aldehydes as potential biomarkers for disease diagnosis. One of the possibilities is to use electrochemical biosensors in point-of-care (PoC), but these need further development to overcome some limitations. Currently, the primary goal is to enhance their metrological parameters in terms of sensitivity and selectivity. Previous findings indicate that peptide OBPP4 (KLLFDSLTDLKKKMSEC-NH2) is a promising...
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Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity
PublikacjaSeven conjugates composed of well-known fluoroquinolone antibacterial agents, ciprofloxacin (CIP) or levofloxacin (LVX), and a cell-penetrating peptide transportan 10 (TP10-NH2) were synthesised. The drugs were covalently bound to the peptide via an amide bond, methylenecarbonyl moiety, or a disulfide bridge. Conjugation of fluoroquinolones to TP10-NH2 resulted in congeners demonstrating antifungal in vitro activity against human...
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Development and Assessment of Regeneration Methods for Peptide-Based QCM Biosensors in VOCs Analysis Applications
PublikacjaCleaning a quartz crystal microbalance (QCM) plays a crucial role in the regeneration of its biosensors for reuse. Imprecise removal of a receptor layer from a transducer’s surface can lead to unsteady operation during measurements. This article compares three approaches to regeneration of the piezoelectric transducers using the electrochemical, oxygen plasma and Piranha solution methods. Optimization of the cleaning method allowed...
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Can Immobilized Artificial Membrane Chromatography Support the Characterization of Antimicrobial Peptide Origin Derivatives?
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Selection of main engines for hopper suction dredgers with the use oobability models
PublikacjaThis paper presents a new original method of selection of main engines for hopper suction dredgers with regard to probabilistic models. It was proposed to use the normal distribution to describe the operational loads of the main receivers. The principles for determination of parameters of load distribution and design power of the main engines were formulated. Lastly, the principles of selection of the size and number of main engines...
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Modelling of mechanical properties of cooper alloys sand cast ship propellers.
PublikacjaBadania właściwości mechanicznych (Rm ,A5) stopów miedzi, stosowanych na pędniki okrętowe, w zależności od ich składu chemicznego i grubości odlewów piaskowych pozwalają na wyznaczenie równań regresji mających zastosowanie do prognozowania wytrzymałości statycznej na rozciąganie (Rm) i wydłużenia plastycznego (A5).Obliczenia wartości Rm i A5 dla wybranych odlewów piaskowych (mosiądz MM55, brązy BA93, BA2 i CMA1) wykazały, że opracowane...
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Numerical calculation wall pressure and stresses in cylindrical silos withconical hopper
PublikacjaOmówiono wyniki numerycznego obliczania naporu materiału sypkiego na ściany silosu. Obliczenia wykonano stosując metodę elementów skończonych i sprężysto idealnie plastyczne prawo konstytutywne według Druckera-Pragera. W analizie uwzględniono wpływ osiowy i mimośrodowy.
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Determination of long-chain aldehydes using a novel quartz crystal microbalance sensor based on a biomimetic peptide
PublikacjaThere is an increasingly popular trend aimed at improvement of fundamental metrological parameters of sensors via implementation of materials mimicking biological olfactory systems. This study presents investigation on usefulness of the peptide mimicking HarmOBP7 region as a receptor element of the piezoelectric sensor for selective analysis of long-chain aldehydes. Identification of odorant binding proteins creates new possibilities...
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Synthesis of novel, peptidic kinase inhibitors with cytostatic/cytotoxic activity
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Copper recovery from model chloride solution using polymer inclusion membranes with 1-decyl-2,4-dimethylimidazle
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