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System for characterisation and multidimensional imaging of seafloor using multibeam sonar data
PublikacjaMultibeam sonars are widely used in applications like high resolution bathymetry measurements, underwater object detection and imaging, etc. Also, they are the promising tool in seafloor characterisation and classification, having several advantages over conventional single beam echosounders. The proposed approach to seafloor classification relies on the combined use of three different techniques. In each of them, a set of descriptors...
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Indukcja procesu pseudostarzenia komórkowego przez inhibitory DNA topoizomerazy II i jego rola w oporności na leki przeciwnowotworowe
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New Polymethoxyflavones from Hottonia palustris Evoke DNA Biosynthesis-Inhibitory Activity in An Oral Squamous Carcinoma (SCC-25) Cell Line
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Discovery and characterization of RecA protein of thermophilic bacterium Thermus thermophilus MAT72 phage Tt72 that increases specificity of a PCR-based DNA amplification
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Dual inhibition of PI3K/Akt signaling and the DNA damage checkpoint in p53-deficient cells with strong survival signaling: implications for cancer therapy
PublikacjaOporność komórek nowotworowych na leki uszkadzjące DNA związana jest ściśle ze zdolnością do utrzymywania blok z fazie G2 cyklu komórkowego. Blok ten regulowany jest przez mechanizmy punktu kontrolnego G2/M oraz szlaki przeżycia komórkowego. W pracy badaliśmy rolę szlaku kinazy PI3K/Akt w funkcjonowaniu punktu kontrolnego cyklu komórkowego i wpływ na przeżycie komórek traktowanych lekiem przeciwnowotworowym - cisplatyną. Nasze...
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Urinary Measurement of Epigenetic DNA Modifications: A Non-Invasive Assessment of the Whole-Body Epigenetic Status in Healthy Subjects and Colorectal Cancer Patients
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The changes of antioxidant defense system caused by quercetin administration do not lead to DNA damage and apoptosis in the spleen and bone marrow cells of rats
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Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells
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Molecular Characterization of a DNA Polymerase from Thermus thermophilus MAT72 Phage vB_Tt72: A Novel Type-A Family Enzyme with Strong Proofreading Activity
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A New Double Digestion Ligation Mediated Suppression PCR Method for Simultaneous Bacteria DNA-Typing and Confirmation of Species: An Acinetobacter sp. Model
PublikacjaWe have designed a new ddLMS PCR (double digestion Ligation Mediated Suppression PCR) method based on restriction site polymorphism upstream from the specific target sequence for the simultaneous identification and differentiation of bacterial strains. The ddLMS PCR combines a simple PCR used for species or genus identification and the LM PCR strategy for strain differentiation. The bacterial identification is confirmed in the...
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Novel anticancer strategy aimed at targeting shelterin complexes by the induction of structural changes in telomeric DNA: hitting two birds with one stone.
PublikacjaThe ends of chromosomes in mammals are composed of telomeric DNA containing TTAGGG repeats, which bind specific proteins called shelterins. This telomeric DNA together with shelterins form a cap that protects the ends of chromosomes from being recognized as sites of DNA damage and from chromosomal fusions. Many very successful antitumor drugs used in the treatment of cancer patients bind to DNA, some of them with a prominent sequence...
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Characterization of a single-stranded DNA-binding-like Protein from Nanoarchaeum equitans - a nucleic acid binding protein with broad substrate specificity
PublikacjaBackground SSB (single-stranded DNA-binding) proteins play an essential role in all living cells and viruses, as they are involved in processes connected with ssDNA metabolism. There has recently been an increasing interest in SSBs, since they can be applied in molecular biology techniques and analytical methods. Nanoarchaeum equitans, the only known representative of Archaea phylum Nanoarchaeota, is a hyperthermophilic, nanosized,...
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Positive solutions to second-order differential equations with dependence on the first-order derivative and nonlocal boundary conditions
PublikacjaIn this paper, we consider the existence of positive solutions for second-order differential equations with deviating arguments and nonlocal boundary conditions. By the fixed point theorem due to Avery and Peterson, we provide sufficient conditions under which such boundary value problems have at least three positive solutions. We discuss our problem both for delayed and advanced arguments α and also in the case when α(t)=t, t∈[0,1]....
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Marek Czachor prof. dr hab.
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Technological Capability and Absorptive Capacity Dynamics through Cluster Organizations, In: Sekliuckienė J., Susnienė R. (Eds). AIB-CEE 2019. Book of abstracts (pp. 127), 6th Academy of International Business Central Eastern European (AIB-CEE) chapter annual conference: „International business in the dynamic environment: changes in digitalization, innovation and entrepreneurship”, Kaunas University of Technology, Lithuania, September 25-27 (eISBN 9786090216378)
PublikacjaThe purpose of the paper is to portrait how members of cluster organizations (COs) perceive the role of clusters in enabling them accumulation of technological capability significant for their innovation. The authors report the findings from the qualitative study based on analysis of four COs from the metal and the highly internationalized ICT industry that concerns the role of knowledge and other cluster benefits in technological...
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Dissociative electron attachment to benzoic acid (C7H6O2)
PublikacjaThe dissociative electron attachment (DEA) to benzoic acid (C6H5COOH) has been studied using an experimental crossed beam setup of a quadrupole mass spectrometer and a trochoidal electron monochromator. Relative partial cross sections for the DEA to produce negative ion fragments show the main channels for dissociation. The comparison of the present results with the ultraviolet photoelectron spectrum of benzoic acid [J. Meeks,...
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Akwarela / Watercolour
Publikacjakatalog dorocznej wystawy Stowarzyszenia Akwarelistów Polskich prezentowanej w Galerii Muzeum regionalnego w Radomsku oraz w Muzeum Miasta Turku im. J. Mehoffera 11.2019. Stowarzyszenie Akwarelistów Polskich 2019,
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On the dervative of the Legendre function of the first kind with respect to its degree [Corrigendum]
PublikacjaSkorygowano błąd matematyczny w pracy: R. Szmytkowski, On the derivative of the Legendre function of the first kind with respect to its degree, J. Phys. A: Math. Gen. Vol. 39(2006) s. 15147-15172 [744014]
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Spotkanie nt. legalizacji pobytu dla studentów zagranicznych
WydarzeniaNa spotkaniu zostanie poruszony temat legalnego pobytu w Polsce, a także studiowania na PG . Spotkanie odbędzie się w j. angielskim i rosyjskim. Poprowadzi je DMWA oraz prawnik z IOM Polska.
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Projekt specjalistyczny. Adaptacje i innowacje - w poszukiwaniu granic
Kursy OnlineProjekt specjalistyczny. Adaptacje i innowacje - w poszukiwaniu granic. Prowadzący: J. Szczepański, A. Szuta.
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Searching for in vitro biomarkers of susceptibility to prostate and cervical cancers by analysis of chromosomal instability, γ-H2AX foci, polymorphisms in DNA repair genes and apoptosis
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Author Correction: Decreased integrity of exercise-induced plasma cell free nuclear DNA – negative association with the increased oxidants production by circulating phagocytes
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High efficiency protocol of DNA extraction from Micromys minutus mandibles from owl pellets: a tool for molecular research of cryptic mammal species
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In vivo evidence of ascorbate involvement in the generation of epigenetic DNA modifications in leukocytes from patients with colorectal carcinoma, benign adenoma and inflammatory bowel disease
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Exploring novel Cd(ii) complexes with 5-methyl-4-imidazolecarboxaldehyde: synthesis, structure, computational insights, and affinity to DNA through switchSense methodology
PublikacjaA series of four Cd(II) complexes with 5-methyl-4-imidazolecarboxaldehyde (L) with different inorganic anions within or outside the coordination sphere of general formula: [CdCl2 L2 ] (1), [CdBr2 L 2] (2), [CdI2L 2] (3), and [CdL4 ](PF6 )2 ·3H2 O (4) was synthesized through one-step and two-step reactions, respectively. All complexes were obtained as colorless crystals without the need for recrystallization and exhibited solubi- lity...
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The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA
PublikacjaMatrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...
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Intercalation complex of imidazoacridinone C-1311, a potential anticancer drug, with DNA helix d(CGATCG)2: stereostructural studies by 2D NMR spectroscopy.
PublikacjaImidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial stage of its action C-1311 forms a relatively stable intercalation complex with DNA, yet it has shown no base-sequence specificity while binding to DNA. In this paper, the d(CGATCG)2:C-1311...
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Intramolecular Proton Transfer in the Radical Anion of Cytidine Monophosphate Sheds Light on the Sensitivities of Dry vs Wet DNA to Electron Attachment-Induced Damage
PublikacjaSingle-strand breaks (SSBs) induced via electron attachment were previously observed in dry DNA under ultrahigh vacuum (UHV), while hydrated electrons were found not able to induce this DNA damage in an aqueous solution. To explain these findings, crossed electron-molecular beam (CEMB) and anion photoelectron spectroscopy (aPES) experiments coupled to density functional theory (DFT) modeling were used to demonstrate the fundamental...
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The Chow Ring of flag manifolds
Dane BadawczeSchubert calculus is the intersection theory of 19th century. Justifying this calculus is the content of the 15th problem of Hilbert. In the course to establish the foundation of algebraic geometry, Van der Vaerden and A. Weil attributed the problem to the determination of the chow ring of flag manifolds G/P, where G is a compact Lie group and P is...
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Influence of PWHT Parameters on the Mechanical Properties and Microstructural Behavior of Multi-Pass GTAW Joints of P92 Steel
PublikacjaThe 9% Cr steels were developed for ultra-supercritical (USC) power plants to meet the requirements of high operating temperature and pressure. These steels are produced to operate at high temperatures where impact toughness is not a concern; however, it becomes important for the welded joints to have good impact toughness at room temperature for manufacturing. The present work investigates the effect of the post-weld heat treatment...
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Effect of antitumor compounds on the yeast topoisomerase II relaxation activity
Dane BadawczeThe datasets contain results of antitumor compounds* (known inhibitors of human topoisomerase alpha II) inhibitory activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions,...
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Malarstwo jest okey. - Jan Buczkowski
PublikacjaKatalog towarzyszący wystawie "Malarstwo jest okey" w Foyer Opery Bałtyckiej w Gdańsku w ramach 3. edycji Festiwalu Kultury Trójmiasta "Metropolia jest okey", który odbył się w dniach 26-30.12.2009. Katalog liczy 120 stron i zawiera tekst krytyczny w języku polskim i angielskim, noty biograficzne artystów w języku polskim i angielskim oraz 55 kolorowych reprodukcji prac artystów (prace autorów: J. Buczkowski s. 16-17, D. Krechowicz...
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Malarstwo jest okey. - Janusz Osicki
PublikacjaKatalog towarzyszący wystawie "Malarstwo jest okey" w Foyer Opery Bałtyckiej w Gdańsku w ramach 3. edycji Festiwalu Kultury Trójmiasta "Metropolia jest okey", który odbył się w dniach 26-30.12.2009. Katalog liczy 120 stron i zawiera tekst krytyczny w języku polskim i angielskim, noty biograficzne artystów w języku polskim i angielskim oraz 55 kolorowych reprodukcji prac artystów (prace autorów: J. Buczkowski s. 16-17, D. Krechowicz...
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Malarstwo jest okey. - Krzysztof Wróblewski
PublikacjaKatalog towarzyszący wystawie "Malarstwo jest okey" w Foyer Opery Bałtyckiej w Gdańsku w ramach 3. edycji Festiwalu Kultury Trójmiasta "Metropolia jest okey", który odbył się w dniach 26-30.12.2009. Katalog liczy 120 stron i zawiera tekst krytyczny w języku polskim i angielskim, noty biograficzne artystów w języku polskim i angielskim oraz 55 kolorowych reprodukcji prac artystów (prace autorów: J. Buczkowski s. 16-17, D. Krechowicz...
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Malarstwo jest okey. -Dominika Krechowicz
PublikacjaKatalog towarzyszący wystawie "Malarstwo jest okey" w Foyer Opery Bałtyckiej w Gdańsku w ramach 3. edycji Festiwalu Kultury Trójmiasta "Metropolia jest okey", który odbył się w dniach 26-30.12.2009. Katalog liczy 120 stron i zawiera tekst krytyczny w języku polskim i angielskim, noty biograficzne artystów w języku polskim i angielskim oraz 55 kolorowych reprodukcji prac artystów (prace autorów: J. Buczkowski s. 16-17, D. Krechowicz...
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A convergence result for mountain pass periodic solutions of perturbed Hamiltonian systems
PublikacjaIn this work, we study second-order Hamiltonian systems under small perturbations. We assume that the main term of the system has a mountain pass structure, but do not suppose any condition on the perturbation. We prove the existence of a periodic solution. Moreover, we show that periodic solutions of perturbed systems converge to periodic solutions of the unperturbed systems if the perturbation tends to zero. The assumption on...
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Maciej Niedostatkiewicz dr hab. inż.
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Crack monitoring in concrete beams under bending using ultrasonic waves and coda wave interferometry: the effect of excitation frequency on coda
PublikacjaConcrete is one of the most widely used construction materials in the world. In recent years, various non-destructive testing (NDT) and structural health monitoring (SHM) techniques have been investigated to improve the safety and control of the current condition of concrete structures. This study focuses on micro-crack monitoring in concrete beams. The experimental analysis was carried out on concrete elements subjected to three-point...
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Detection and Imaging of Debonding in Adhesive Joints of Concrete Beams Strengthened with Steel Plates Using Guided Waves and Weighted Root Mean Square
PublikacjaStrengthening of engineering structures is an important issue, especially for elements subjected to variable loads. In the case of concrete beams or slabs, one of the most popular approaches assumes mounting an external reinforcement in the form of steel or composite elements by structural adhesives. A significant disadvantage of adhesive joints is the lack of access to the adhesive film for visual condition assessment, thus, there...
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Failure characterisation of sandwich beams using integrated acoustic emission and digital image correlation techniques
PublikacjaThe paper presents the experimental study of the failure behaviour of sandwich beams subjected to bending. The samples examined are sandwich beams made of polyethylene terephthalate foam core and glass fibre-reinforced polymer laminate face sheets. In a series of experiments, it has been proposed to integrate diagnostic techniques with acoustic emission and digital image correlation to accurately track the cracking process on the...
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Discrete element method modelling of elastic wave propagation in a meso-scale model of concrete
PublikacjaThis paper deals with the accurate modelling of ultrasonic wave propagation in concrete at the mesoscopic level. This was achieved through the development of a discrete element method (DEM) model capable of simulating elastic wave signals comparable to those measured experimentally. The main objective of the work was to propose a novel methodology for constructing a meso-scale model of concrete dedicated to the analysis of elastic...
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A study on microcrack monitoring in concrete: discrete element method simulations of acoustic emission for non-destructive diagnostics
PublikacjaThe research is focused on the monitoring of fracture evolution in concrete beams under three-point bending using the acoustic emission technique and the discrete element method. The main objective of the study was to numerically and experimentally investigate the mechanism behind the generation of elastic waves during acoustic emission events and their interaction with micro- and macro-cracking in concrete beams under monotonic...
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Non-Destructive Diagnostics of Concrete Beams Strengthened with Steel Plates Using Modal Analysis and Wavelet Transform
PublikacjaExternally bonded reinforcements are commonly and widely used in civil engineering objects made of concrete to increase the structure load capacity or to minimize the negative effects of long-term operation and possible defects. The quality of adhesive bonding between a strengthened structure and steel or composite elements is essential for effective reinforcement; therefore, there is a need for non-destructive diagnostics of adhesive...
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RMS-based damage identification in adhesive joint between concrete beam and steel plate using ultrasonic guided waves
PublikacjaAdhesive joints have numerous applications in many branches of industry, such as civil engineering, automotive, aerospace and shipbuilding. As with most structural elements, adhesive joints can experience any damage mechanism, which induces the need for diagnostic testing. Ultrasonic waves are widely used for non-destructive inspection of many structures and their elements, including adhesive joints. Guided wave propagation method...
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Coda wave interferometry in monitoring the fracture process of concrete beams under bending test
PublikacjaEarly detection of damage is necessary for the safe and reliable use of civil engineering structures made of concrete. Recently, the identification of micro-cracks in concrete has become an area of growing interest, especially using wave-based techniques. In this paper, a non-destructive testing approach for the characterization of the fracture process was presented. Experimental tests were made on concrete beams subjected to mechanical...
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Hanna Obracht-Prondzyńska dr inż. arch.
OsobyDr inż. arch. Hanna Obracht-Prondzyńska Adiunktka na Uniwersytecie Gdańskim w Zakładzie Gospodarki Przestrzennej, nauczycielka akademicka ucząca projektowania urbanistycznego i analizy danych. Architektka i urbanistka zajmującą się projektowaniem w oparciu o dane. Tytuł doktora nauk inżynieryjno-technicznych w dyscyplinie architektura i urbanistyka obroniła z wyróżnieniem w 2020 r. na Wydziale Architektury Politechniki Gdańskiej,...
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A note on total reinforcement in graphs
PublikacjaIn this note we prove a conjecture and inprove some results presendet in a recent paper of N. Sridharan, M.D. Elias, V.S.A. Subramanian, Total reinforcement number of a graph, AKCE Int. J. Graphs Comb. 4 (2) (2007) 197-202.
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Effect of new bisacridines IKE16, IKE18 and IE10 on the yeast topoisomerase II relaxation activity
Dane BadawczeThe datasets contain the results of new bisacridines IKE16, IKE18 and IE10 inhibition activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions, DNA topo are significant...
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Minimum inhibitory concentrations (MICs) determination of selected human topoisomerase II alpha and bacterial DNA gyrase inhibitors against fungal strains
Dane BadawczeThe datasets contain the results of determining the MIC (Minimal Inhibitory Concentration) value of known compounds* (inhibitors of human topoisomerase II alpha and bacterial DNA gyrase) against C. albicans SC5314, C. glabrata ATCC 90030, C. krusei ATCC 6258 and C. parapsilosis ATCC 22019 and Saccharomyces cerevisiae ATCC 9763 by the modified M27-A3...
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Shared processor scheduling of multiprocessor jobs
PublikacjaWe study a problem of shared processor scheduling of multiprocessor weighted jobs. Each job can be executed on its private processor and simultaneously on possibly many processors shared by all jobs. This simultaneous execution reduces their completion times due to the processing time overlap. Each of the m shared processors may charge a different fee but otherwise the processors are identical. The goal is to maximize the total...