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Wyniki wyszukiwania dla: INVERSE AGONIST
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Volunteerism in the last year as a moderator between empathy and altruistic social value orientation: An exploratory study
PublikacjaVolunteerism is a sustained prosocial activity, and young adults are one of the most important targets for organizations recruiting volunteers. Empathy and altruistic social value orientation measured by a decomposed game are dispositional traits that might foster engagement in volunteerism. Using a self-report online-based questionnaire study on two groups of young adults (aged 18-35, N = 224 non-volunteers and N = 178 volunteers...
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Inżynieria odwrotna bazy paliw płynnych w Gdańsku
PublikacjaArtykuł prezentuje prace z zakresu pozyskania danych o zbiornikach bazy paliw płynnych w Gdańsku. Przedstawione rozwiązanie nie ogranicza się tylko do stworzenia (rejestracji) chmury punktów, ale jest próbą wskazania użycia naziemnego skaningu laserowego do stworzenia bazy informacji o bazie paliw – w tym głównie geometrii zbiorników. Autorzy prezentują proces inwentaryzacji, rejestrację chmury punktów oraz wskazują zasady tworzenia...
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Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5- methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII
PublikacjaA series of novel N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines 9 e41 have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and cancer-associated isozymes CA IX and XII. Against the human CA I investigated compounds showed KI in the range of 87e6506 nM, toward hCA II ranging from 7.8 to 4500 nM,...
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Comparison of target strength (TS) distributions obtained by means of the use of direct and indirect techniques in sea cages
PublikacjaThe aim of this study is to verify the reliability of a processing application developed for the indirect measurement of target strength (TS), with a view to the integration into a single-beam system for its utilization in fish farms. Dorsal and ventral measurements are carried out for gilt-head sea-bream (Spams Aurata) for 5 size classes using a split-beam EK60 echosounder and single-beam data obtained from one of the channels...
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Material Parameters Identification of Historic Lighthouse Based on Operational Modal Analysis
PublikacjaIn the present paper, the identification of the material parameters of a masonry lighthouse is discussed. A fully non-invasive method was selected, in which the material properties were determined via numerical model validation applied to the first pair of natural frequencies and their related mode shapes, determined experimentally. The exact structural model was built by means of the finite element method. To obtain experimental...
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Zero-range potentials for Dirac particles: Bound-state problems
PublikacjaA model in which a massive Dirac particle in $\mathbb{R}^{3}$ is bound by $N\geqslant1$ spatially distributed zero-range potentials is presented. Interactions between the particle and the potentials are modeled by subjecting a particle's bispinor wave function to certain limiting conditions at the potential centers. Each of these conditions is parametrized by a $2\times2$ Hermitian matrix (or, equivalently, a real scalar and a...
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Analysis of antibiotic resistance in Escherichia coli isolated from the Reda River and the Oliwski Stream using basic statistical methods = Zastosowanie metod ststystycznych do analizy antybiotykoodporności bakterii wskaźnikowych pochodzących z rzeki Redy i Potoku Oliwskiego
PublikacjaIn this study distribution of antimicrobial resistance patterns among fecal indicator bacteria (Escherichia coli and Enterococcus spp.) was examined in two watercourses. The susceptibility analyses were carried out against the antimicrobial agents, important in treating human E. coli and enterococcal infection. Water samples were obtained from the Oliwski Stream and from the Reda River. On each watercourse the five representative...
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Audible noise in ship’s electrical drive systems with frequency converters
Dane BadawczeThe presented dataset is part of research focusing on the impact of the ship's electrical drive systems with frequency converters on vibrations and the level of audible noise on ships.
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Experimental verification of a new method of loop resistance testing in low voltage systems with residual current devices
PublikacjaA periodical verification of the effectiveness of protection against electric shock shall be performed in low voltage systems. The scope of this verification includes loop impedance/resistance testing. If a residual current device is installed in a tested circuit, this testing is problematic. A residual current device trips out during the test, because of the high value of measurement current. This precludes the execution of the...
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Matrix-based robust joint fingerprinting and decryption method for multicast distribution of multimedia
PublikacjaThis paper addresses the problem of unauthorized redistribution of multimedia content by malicious users (pirates). The solution proposed here is a new joint fingerprinting and decryption method which meets the requirements for both imperceptibility and robustness of fingerprints and scalability in terms of design and distribution of fingerprinted multimedia content. The proposed method uses a simple block cipher based on matrix...
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Cuticular lipids of insects as potential biofungicides
PublikacjaThe term ''lipids'' refers to fatty acids, their derivatives and substances related with them biochemically or by the functions in the body. Lipids include compounds with different chemical structure. There are lipids with structures based on long-chain carboxylic acids and their direct derivatives, namely: fatty acids, alkanes, some alkenes, aldehydes and long chain alcohols and their derivatives (esters). The variety of lipid...
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Discovering relationships between data in an enterprise information system using log analysis
PublikacjaEnterprise systems are inherently complex and maintaining their full, up-to-date overview poses a serious challenge to the enterprise architects’ teams. This problem encourages the search for automated means of discovering knowledge about such systems. An important aspect of this knowledge is understanding the data that are processed by applications and their relationships. In our previous work, we used application logs of an enterprise...
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Molecular Umbrella as A Nanocarrier for Antifungals
PublikacjaA molecular umbrella composed of two O‐sulfated cholic acid residues was applied for the construction of conjugates with cispentacin, containing a “trimethyl lock” (TML) or o‐dithiobenzylcarbamoyl moiety as a cleavable linker. Three out of five conjugates demonstrated antifungal in vitro activity against C. albicans and C. glabrata but not against C. krusei, with MIC90 values in the 0.22–0.99 mM range and were not hemolytic. Antifungal...
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A Trisection Filter Design With Negative Slope of Frequency-Dependent Crosscoupling Implemented in Substrate Integrated Waveguide (SIW)
PublikacjaThis letter reports on a novel realization of a microwave bandpass filter in a triplet configuration with a frequency-dependent crosscoupling implemented in substrate integrated waveguide (SIW). The design involves implementing dispersive coupling with a negative slope, a feature that allows the capabilities of the classic triplet topology to be extended. In this particular case, the implementation of two transmission zeros on...
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The Attitude of Polish Entrepreneurs to the Fact of Staging the Mega Sport Event - the Case of Pomeranian SMEs Towards Euro 2012
PublikacjaIn the course of preparations to the 2012 European Football Championship (Euro 2012) many doubts have arisen as to the actual cost-benefit balance affecting the hosting country. The event is accompanied by intense promotion of the agglomeration and the region, especially abroad. In effect, one can anticipate the competitive position of both the region and the businesses operating there to improve. The investigation whether the...
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Azo group(s) in selected macrocyclic compounds
PublikacjaAzobenzene derivatives due to their photo- and electroactive properties are an important group of compounds finding applications in diverse fields. Due to the possibility of controlling the trans–cis isomerization, azo-bearing structures are ideal building blocks for development of e.g. nanomaterials, smart polymers, molecular containers, photoswitches, and sensors. Important role play also macrocyclic compounds well known for...
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Excited-state proton transfer and geminate recombination in the molecular cage of β-cyclodextrin
PublikacjaExcited-state proton transfer and geminate recombination in aqueous heptakis(2,6-di-O-methyl)-β-cyclodextrin have been compared with those in water by monitoring the photoinduced prototropic tautomerization of 6-hydroxyquinoline, which occurs via forming anionic intermediate. Enol deprotonation decelerates by 18 times whereas its reverse process accelerates slightly with encapsulation. The imine protonation of the intermediate...
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Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents
PublikacjaImproved derivatives of mycophenolic acid (MPA) are necessary to reduce the frequency of adverse effects, this drug exerts in treated patients. In this study, MPA was coupled with N-(x-hydroxyalkyl)-9-acridone-4-carboxamides or N-(x-hydroxyalkyl)acridine-4-carboxamides to give respective ester conjugates upon Yamaguchi protocol. This esterification required protection of phenol group in MPA. Designed conjugates revealed higher...
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Występowanie bakterii siarkowych a jakość wód podziemnych ujęcia Osowa
PublikacjaAbstrakt. Microorganisms that live in groundwater should be considered not only from the sanitary-hygienic point of view but also in terms of adverse changes in groundwater chemistry in the aquifer layer and its negative influence on the installed devices. For these reasons, it is important to correct approach to the problem of bacterial contamination of groundwater. The paper presents selected results of physicochemical and bacteriological...
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PUBLIC SPACES FOR LOCAL LIFE / Shared values in diversified urban communities as a foundation for participatory provision of local public spaces, 23-27 May 2017, Ljubljana Slovenia
PublikacjaThe Urban Planning Institute of the Republic of Slovenia (UIRS) and partners hosted a 5-day international event addressing participatory planning of local urban public space in socially, economically and ethnically diverse communities. The event was structured in three interrelated activities: a seminar, a workshop and a field-trip. Special emphasis was given to the means of revealing shared values that local inhabitants and other...
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Induction machine behavioral modeling for prediction of EMI propagation.
PublikacjaThis paper presents the results of wideband behavioral modeling of an induction machine (IM). The proposed solution enables modeling the IM differential- and common-mode impedance for a frequency range from 1 kHz to 10 MHz. Methods of parameter extraction are derived from the measured IM impedances. The developed models of 1.5 kW and 7.5 kW induction machines are designed using the Saber Sketch scheme editor and simulated in the...
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IPMSM rotor position estimator based on analysis of phase current derivatives
PublikacjaThis paper describes an algorithm for estimation of IPMSM angular rotor position. The algorithm uses derivatives of motor phase currents resulting from PWM modulation to obtain the rotor position. The presented method is designed for medium- and high-speed range, since it is based on determination of the EMF vector. Algorithm is characterised by a very simple formulae. The calculation of rotor position is performed in every PWM...
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Wireless Charging Station Design for Electric Scooters: Case Study Analysis
PublikacjaThis study proposes an example of a wireless charging station design for a small-scale vehicle available on the market. The article analyzes basic transmitter inverter topologies and their compensation methods in terms of flexibility of control, tolerance to uncertainty in positioning, and the possibility of decreasing the integration price. Our comprehensive analysis focuses on the battery voltage range, energy capacity, cost,...
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Tunable Dielectric Switching of (Quinuclidinium)[MnCl4] Hybrid Compounds
PublikacjaInorganic−organic hybrid QMnCl (Q = quinuclidinium) crystals were synthesized and characterized. The X-ray and variable-temperature IR/Raman analysis demonstrate that the crystals undergo a reversible structural phase transition, which originates from an order−disorder process and is related to the dynamics of the organic Q cation. Dielectric function measurements disclose a switchability between low (“OFF”) and high (“ON”) dielectric...
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Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
PublikacjaIn spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...
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STANY NIEUSTALONE TOWARZYSZĄCE POMIAROWI IMPEDANCJI PĘTLI ZWARCIA W OBWODACH WYJŚCIOWYCH ZASILACZY BEZPRZERWOWYCH UPS
PublikacjaW pracy przedstawiono metodykę i wyniki pomiarów stanów nieustalonych w zasilaczu bezprzerwowym (UPS) typu on - line. Do rejestracji zdarzeń po stronie zasilania i na wyjściu UPS wykorzystano dwa przyrządy do pomiaru jakości energii elektrycznej zsynchronizowane czasowo. Rejestratory kompresują uzyskane dane pomiarowe, co może wprowadzać dodatkowe błędy pomiaru wielkości mierzonych – napięć i prądów. Dodatkowe rejestracje oscyloskopem...
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CDIO IN GDANSK: PEOPLE-ORIENTED STRATEGY
PublikacjaThe CDIO system implementation in Poland meets problems and Gdansk University of Technology (GUT) is still a single higher education institution in Poland accepted as the member of CDIO Initiative. The paper detects and characterizes the existing problems to be solved. In particular, the different groups of people are considered as supporters or fighters against CDIO idea, their attitudes being considered and applied strategy demonstrated. The...
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Synthesis, Characterization and Biological Investigations of Half-Sandwich Ruthenium(II) Complexes Containing Benzimidazole Moiety
PublikacjaHalf-sandwich Ru(II) complexes belong to group of biologically active metallo-compounds with promising antimicrobial and anticancer activity. Herein, we report the synthesis and characteri- zation of arene ruthenium complexes containing benzimidazole moiety, namely, [(η6-p-cymene)RuC l(bimCOO)] (1) and [(η6-p-cymene)RuCl2(bim)] (2) (where bimCOO = benzimidazole-2-carboxylate and bim = 1-H-benzimidazole). The compounds were characterized...
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Phylogenetic analysis of Oncidieae subtribe - ITS1-5,8S-ITS2
Dane BadawczeThe dataset contains alignment and consensus matrix files, and results of phylogenetic analysis of ITS1- 5,8S-ITS2 region from 186 orchid species considered to belong Oncidieae subtribe. Sequences were assessed from NCBI GeneBank (list of all records with identifiers in the separate file)
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Phylogenetic analysis of Oncidieae subtribe - matK plastid region
Dane BadawczeThe dataset contains alignment and consensus matrix files, and results of phylogenetic analysis of plastid matK region from 186 orchid species considered to belong Oncidieae subtribe. Sequences were assessed from NCBI GeneBank (list of all records with identifiers in the separate file)
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Prime-Boost Vaccination with Toxoplasma Lysate Antigen, but Not with a Mixture of Recombinant Protein Antigens, Leads to Reduction of Brain Cyst Formation in BALB/c Mice
PublikacjaIntroduction Infection with the ubiquitous parasite Toxoplasma gondii is a threat for immunocompro- mised patients and pregnant women and effective immune-prophylaxis is still lacking. Methods Here we tested a mixture of recombinant T . gondii antigens expressed in different develop- mental stages, i.e., SAG1, MAG1 and GRA7 (SMG), and a lysate derived from T . gondii tachyzoites (TLA) for prophylactic vaccination against cyst formation....
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Elżbieta Marczak dr inż. arch.
OsobyElżbieta Marczak (dr inż. arch.) - adiunkt na Wydziale Architektury Politechniki Gdańskiej, zatrudniona Katedrze Architektury Miejskiej i Przestrzeni Nadwodnych (dawniej Katedra Architektury Morskiej i Przemysłowej, od roku 1997). Studia na Wydziale Architektury PG ukończyła w roku 1995. Stopień naukowy doktora uzyskała w 2006 r. przedstawiając pracę p.t. Architektura statków na tle rozwoju transportu morskiego. Jej badania naukowe...
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Description Logic As A Common Software Engineering Artifacts Language
PublikacjaDescription logic is proposed as a powerful language able to support chosen software engineering process tasks like: requirements engineering, software architecture definition, software design and configuration management. To do this there is presented a correspondence between description logic and UML. Description logic based integrated software engineering process framework is proposed which owing to automatic knowledge inferring...
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Reliable underwater communication system for shallow coastal waters
PublikacjaThis paper presents a reliable and robust low data rate spread spectrum approach which is implemented in the acoustic underwater communication system for shallow coastal waters. It shows operation assumptions of spread spectrum techniques based on the wellknown Shannon equation. It describes two methods of spread spectrum: frequency hopping spread spectrum and direct sequence spread spectrum; their block diagram and their characteristics...
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Analysis of load carrying capacity and destruction mechanism of an intermediate anchorage steel plate for pillar jib crane
PublikacjaPillar jib cranes are often mounted to existing floors with the use of an intermediate anchorage steel plate instead of using independent foundations, what is shown in the figure. Standards for steel design provide only basic rules for the design of such an intermediate plate. This study presents a simple design approach by using a numerical model in order to analyze different parameters that have significant influence in the anchorage...
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Local Dye Concentration and Spectroscopic Properties of Monomer−Aggregate Systems in Hybrid Porous Nanolayers
PublikacjaAnalysis of absorption, fluorescence, and time-resolved emission spectra of rhodamine 6G in hybrid porous nanolayers at high dye concentration allowed identification of two fluorescent species: monomers and fluorescent aggregates. The method of determination of mean local concentration of aggregates in matrices is proposed based on the energy transfer process between monomers and fluorescent aggregates. Evaluation of aggregate...
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Cavitation erosion degradation of Belzona® coatings
PublikacjaIn hydrocarbon and maritime industry there is a constant need of materials and coatings withstanding severe conditions. One of adverse phenomena present there is cavitation erosion. The paper presents evaluation of cavitation resistance of three different steel coatings. Belzona 2141 (ACR-Fluid Elastormer), 1321 (Ceramic S-Steal) and 5831 (ST-Barrier) were deployed on P110 steel and subjected to ultrasound cavitation in distilled...
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Sectors in Poland - Patterns of Concentration
PublikacjaThe main aim of the paper presented below, is to analysefrom theoretical point of view market concentration as economicproblem. The authors come out of defining market concentration, theypresent basic concentration measures, and characterize sectors onPoland on that ground. In the empirical part, the authors haveanalysed patterns of concentration of 35 sectors in Poland in timeperiod 1997-2006. We draw on recently made available...
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Determination of the substances potentially allergenic in water
PublikacjaPersonal care chemicals are continuously released into environment through domestic and industrial wastewater, causing adverse effects on human health. Their presence can be detected in different environmental compartments. A group of chemicals included in most personal care products are the allergen fragrances. In the present work, simple and rapid methodology based on ultrasound-assisted emulsification-microextraction (USAEME)...
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Nonlinear Interaction of Magnetoacoustic Modes in a Quasi-Isentropic Plasma Flow
PublikacjaThe nonlinear interaction of magnetoacoustic waves in a plasma is analytically studied. A plasma is an open system. It is affected by the straight constant equilibrium magnetic flux density forming constant angle with the wave vector which varies from 0 till . The nonlinear instantaneous equation which describes excitation of secondary wave modes in the field of intense magnetoacoustic perturbations is derived by use of projecting....
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Exchange-Traded Funds in Europe
PublikacjaExchange-Traded Funds in Europe provides a single point of reference on a diverse set of regional ETF markets, illuminating the roles ETFs can play in risk mitigation and speculation. Combining empirical data with models and case studies, the authors use diffusion models and panel/country-specific regressions—as well as graphical and descriptive analyses— to show how ETFs are more than conventional, passive investments. With new...
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Multi-layered tissue head phantoms for noninvasive optical diagnostics
PublikacjaExtensive research in the area of optical sensing for medical diagnostics requires development of tissue phantoms with optical properties similar to those of living human tissues. Development and improvement of in vivo optical measurement systems requires the use of stable tissue phantoms with known characteristics, which are mainly used for calibration of such systems and testing their performance over time. Optical and mechanical...
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New Complementary Resonator for Permittivity- and Thickness-Based Dielectric Characterization
PublikacjaThe design of high-performance complementary meta-resonators for microwave sensors featur-ing high sensitivity and consistent evaluation of dielectric materials is challenging. This paper presents the design and implementation of a novel complementary resonator with high sensi-tivity for dielectric substrate characterization based on permittivity and thickness. A comple-mentary crossed arrow resonator (CCAR) is proposed and integrated...
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Nonlinear material identification of heterogeneous isogeometric Kirchhoff–Love shells
PublikacjaThis work presents a Finite Element Model Updating inverse methodology for reconstructing heterogeneous materialdistributions based on an efficient isogeometric shell formulation. It uses nonlinear hyperelastic material models suitable fordescribing incompressible material behavior as well as initially curved shells. The material distribution is discretized by bilinearelements such that the nodal values...
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Spatial Differences in the Chemical Composition of Surface Water in the Hornsund Fjord Area: A Statistical Analysis with A Focus on Local Pollution Sources
PublikacjaSurface catchments in Svalbard are sensitive to external pollution, and yet what is frequently considered external contamination may originate from local sources and natural processes. In this work, we analyze the chemical composition of surface waters in the catchments surrounding the Polish Polar Station in Svalbard, Hornsund fjord area. We have pooled unpublished and already published data describing surface water composition...
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Cost-Efficient Bi-Layer Modeling of Antenna Input Characteristics Using Gradient Kriging Surrogates
PublikacjaOver the recent years, surrogate modeling has been playing an increasing role in the design of antenna structures. The main incentive is to mitigate the issues related to high cost of electromagnetic (EM)-based procedures. Among the various techniques, approximation surrogates are the most popular ones due to their flexibility and easy access. Notwithstanding, data-driven modeling of antenna characteristics is associated with serious...
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Theoretical and experimental analysis of guided wave propagation in plate-like structures with sinusoidal thickness variations
PublikacjaGuided waves have attracted significant attention for non-destructive testing (NDT) and structural health monitoring (SHM) due to their ability to travel relatively long distances without significant energy loss combined with their sensitivity to even small defects. Therefore, they are commonly used in damage detection and localization applications. The main idea of incorporating guided waves in NDT and SHM is based on processing...
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Peptide dendrimers as antifungal agents and carriers for potential antifungal agent—N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐ diaminopropanoic acid—synthesis and antimicrobial activity
PublikacjaA series of peptide dendrimers and their conjugates with antimicrobial agent FMDP (N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐diamino‐propanoic acid) were synthesized. The obtained compounds were tested for the antibacterial and antifungal activity. All novel dendrimers displayed much better activity against the tested strains than FMDP itself. Moreover, their conjugates with FMDP also exhibited antimicrobial activity. The most promising molecules...
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Action Plan “Women”
PublikacjaEmployees of a company are not the first alternative coming into one’s mind when searching suitable successor for the business. Those belonging to the company’s management group are in many cases asked for their interest in being a successor, but the lower level an employee is in the hierarchy, the less probably he/she is inquired of his/her interest in becoming a successor. The contemporary entrepreneur may have had conflicts...
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Service-based Resilience for Embedded IoT Networks
PublikacjaEmbedded IoT networks are the backbone of safety-critical systems like smart factories, autonomous vehicles, and airplanes. Therefore, resilience against failures and attacks should be a prior concern already in their design stage. In this study, we introduce a service-based network model as an MILP optimization problem for the efficient deployment of a service overlay to the embedded network by meeting QoS and resilience requirements....