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Wyniki wyszukiwania dla: EXHALED BREATH CONDENSATES (EBC)
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Integrating modelling, simulation and data management tools to create a planning support system for the improvement of air quality by urban planning solutions
PublikacjaThe urbanization pressure requires urban planners, designers, and policy makers to be more responsive to the challenges related to improving the quality of the urban environment and the living conditions of the inhabitants. One of the many environmental issues that need to be taken into account is urban air pollution. As the process of urban ventilation and air pollution dis-persion is significantly affected by the urban layout,...
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Gluten-Free Bread with Cricket Powder—Mechanical Properties and Molecular Water Dynamics in Dough and Ready Product
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Effect of fortification with calcium from eggshells on bioavailability, quality, and rheological characteristics of traditional Polish bread spread
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Active Double-Layered Films Enriched with AgNPs in Great Water Dock Root and Pu-Erh Extracts
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Can a city reach energy self-sufficiency by means of rooftop photovoltaics? Case study from Poland
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Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells
PublikacjaW przedstawionych badaniach określano mechanizm śmierci komórkowej indukowanej przez imidazoakrydon C-1311 (Symadex) w komórkach HT-29 ludzkiego raka jelita grubego, które wykazywały szczególną wrażliwość na ten związek w eksperymentalnych modelach in vitro i in vivo. Przy stężeniu odpowiadającemu dawce IC99, związek powodował zahamowanie progresji cyklu komórkowej w fazie S po czym następował blok w fazie G2. Po czasach 48-96...
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Modulation of G2 arrest enhances cell death induced by the antitumor 1-nit-roacridine derivative, Nitracrine
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The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model
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LY294002 and sorafenib as inhibitors of intracellular survival pathways in the elimination of human glioma cells by programmed cell death
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Glucose oxidase as an important yet overlooked factor determiningthe antibacterial activity of bee pollen and bee bread
PublikacjaBee pollen (BP) and bee bread (BB) have attracted great attention due to their biological activities including antibacterial activity. However, the mechanism of antibacterial activity is largely unknown. Therefore, we aimed to characterise the antibacterial effect of BP and BB aqueous extracts against bacterial pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis and Enterococcus faecalis)...
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Electrochemistry/mass spectrometry (EC/MS) for fast generation and identification of novel reactive metabolites of two unsymmetrical bisacridines with anticancer activity.
PublikacjaThe development of a new drug requires knowledge about its metabolic fate in a living organism, regarding the comprehensive assessment of both drug therapeutic activity and toxicity profiles. Electrochemistry (EC) coupled with mass spectrometry (MS) is an efficient tool for predicting the phase I metabolism of redox-sensitive drugs. In particular, EC/MS represents a clear advantage for the generation of reactive drug transformation...
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Electrical Propterties of Solution Mixtures for Bath Supervision in Ambient Assisted Living
PublikacjaImpedance properties of bath solution are compared. Any ingredient such as soap, shampoo or bathing salt changes bath-solution’s electrical properties eg. impedance. We have measured and analysed influence of typical bathing ingredients on electrical properties of the solution. We investigate impedance changes over frequency range from 100Hz tu 100kHz as it is most applicable for person detection. Electrical properties of bath...
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CD99 correlates with low cyclin D1, high topoisomerase 2 status and triple negative molecular phenotype but is prognostically irrelevant in breast carcinoma
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Modulation of mRNA and protein levels of CYP1A1, 1A2, and 1B1 in nontumorigenic breast epithelial cells (MCF10A) by cabbage juice and its active components
PublikacjaZbadano wpływ soków z kapusty oraz występujących w nich pochodnych indolowych i sulforafanu na poziom ekspresji enzymów odpowiedzialnych za metabolizm ksenobiotyków w tym estrogenów. Wykazano, że soki z kapusty i izolowane substancje mają podobny wpływ na poziom mRNA i białek enzymatycznych.
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Modulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,30-diindolylmethene in human breast epithelial cell lines
PublikacjaThe aim of this study was to evaluate the effect of white cabbage and sauerkraut juices of different origin and indole-3-carbinol (I3C) and diindolylmethane (DIM) on expression of CYP19 gene encoding aromatase, the key enzyme of estrogen synthesis.Remarkable differences in the effect on CYP19 transcript and protein level were found between the cab- bage juices (in 2.5-25 mL/L concentrations) and indoles (in 2.5-50 lM doses) in...
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PARP inhibition potentiates the cytotoxic activity of C-1305, a selective inhibitor of topoisomerase II, in human BRCA1-positive breast cancer cells
PublikacjaTwo cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability.Approximately 5-10% of breast and ovarian cancers result from inherited alterations or mutations in these genes.Remarkably, BRCA1/BRCA2-deficient cells are hypersensitive to selective inhibition of poly(ADPribose) polymerase 1 (PARP-1),...
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LF NMR spectroscopy analysis of water dynamics and texture of Gluten-Free bread with cricket powder during storage
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Cadmium and lead content in gluten and gluten-free bread available on the Polish market – potential health risk to consumers
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Review Ferenc Hörcher, A Political Philosophy of Conservatism Prudence, Moderation and Tradition, Great Britain 2020, pp. 210.
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In Silico Safety Assessment of Bacillus Isolated from Polish Bee Pollen and Bee Bread as Novel Probiotic Candidates
PublikacjaBacillus species isolated from Polish bee pollen (BP) and bee bread (BB) were characterized for in silico probiotic and safety attributes. A probiogenomics approach was used, and in-depth genomic analysis was performed using a wide array of bioinformatics tools to investigate the presence of virulence and antibiotic resistance properties, mobile genetic elements, and secondary metabolites. Functional annotation and Carbohydrate-Active...
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260. The role of patients and doctors in making decisions about the choice of the kind of adjuvant treatment in early brest cancer
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Antipsychotic drug prescription sequence analysis in relation to death occurrence and cardiometabolic drug usage: A retrospective longitudinal study
PublikacjaThe potential role of antipsychotics in increasing cardiovascular risk of mortality is still debated. The aim of this study was to assess the death risk associated with sequences of first-generation antipsychotic (FGA) and second-generation antipsychotic (SGA) prescriptions, including clozapine and lithium, and drugs for cardiometabolic diseases. We conducted a retrospective longitudinal analysis involving 84,881 patients who received...
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Freeze-Up Ice Jam Formation in the River Bend, a Case Study on the Inner Mongolia Reach of Yellow River
PublikacjaConcern has been expressed regarding the impacts of climate change on river ice and ice jam formation in cold regions. Ice jams are easily initiated in bends and narrow channels and cause disasters. In this study, observations and remote sensing monitoring are used to study the freeze-up ice jam formation of bends. Sediment transport and freezing process of the river interact, influencing bed changes profile and sedimentary budget....
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Production of phenolics and flavonoids with antioxidant evaluations of Brunfelsia pauciflora (Cham. &Schltdl.) Benth. through in vitro propagated cultures.
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Konkurs ERC w programie HORYZONT 2020
WydarzeniaCelem szkolenia jest przekazanie informacji o konkursie Europejskiej Rady ds. Badań (European Research Council) ogłoszonym w programie Horyzont 2020.
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Konkurs ERC w programie HORYZONT 2020
WydarzeniaCelem szkolenia jest przekazanie informacji o konkursie Europejskiej Rady ds. Badań (European Research Council) ogłoszonym w programie Horyzont 2020. Organizator: Regionalny Punkt Kontaktowy Programów Ramowych UE
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Maksymalny stopień zbrojenia poprzecznego elementów żelbetowych wg zasad wymiarowania przyjętych w EC:2002, DIN:2001, PN:2002.
PublikacjaW pracy przedstawiono problematykę maksymalnego stopnia zbrojenia na ścinanie elementów żelbetowych, pokazaną na tle wymagań normowych europejskich oraz niemieckich i polskich. Uzyskane wyniki porównano z danymi eksperymentalnymi.
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GC-MS-based untargeted metabolomics of plasma and urine to evaluate metabolic changes in prostate cancer
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Volatile organic compounds in gastrointestinal stromal tumour tissue originating from patient-derived xenografts
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Preparation and Characterization of Films Based on Disintegrated Bacterial Cellulose and Montmorillonite
PublikacjaThe food packaging materials from natural polymers including polysaccharides offer an ecologically important alternative to commonly used synthetic, non-biodegradable counterparts. The purpose of this work was to modify of bacterial cellulose (BC) leading to the improvement of its functional properties in terms of use as a food packaging material. Effects of disintegration of BC and addition of montmorillonite (MMT) on its water...
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Allelic length of a CA dinucleotide repeat in theegfr gene correlates with the frequency of amplifications of this sequence—first results of an inter-ethnic breast cancer study
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Environmental tracers and groundwater residence time indicators reveal controls of arsenic accumulation rates beneath a rapidly developing urban area in Patna, India
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Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
PublikacjaThe molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 genes in BC patients and in BC organoids (3D cell cultures obtained from breast cancer tissues). We observed the same correlation in the...
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Jarosław Łuszcz dr hab. inż.
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Improved conformational space annealing method to treat β-structure with the UNRES force-field and to enhance scalability of parallel implementation
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Geldanamycin-Induced Osteosarcoma Cell Death Is Associated with Hyperacetylation and Loss of Mitochondrial Pool of Heat Shock Protein 60 (Hsp60)
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Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells
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The Effects of Morus alba L. Fortification on the Quality, Functional Properties and Sensory Attributes of Bread Stored under Refrigerated Conditions
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Mercury in Different Feather Types from Great Cormorants (Phalacrocorax carbo L.) Inhabiting the Vistula Lagoon Ecosystem in Poland
PublikacjaTotal mercury levels in different feather types (down, contour, tail and flight) in Great Cormorants (Phalacrocorax carbo L.) were determined using CV-AAS. Feathers from Great Cormorants inhabiting the Vistula Lagoon ecosystem have an average Hg level of 7.14 ± 3.99 (μg/g w.w.). Age-dependent concentrations of Hg were statistically significant (ANOVA Kruskal-Wallis, p < 0.0001). There were also significant differences in Hg levels...
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Evaluation of solid phase extraction for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broth
PublikacjaGlycerol is mainly a by-product of fat splitting and biodiesel production. This study examined the use of chemically modified silica gels for downstream separation of propane-1,3-diol and butan-1-ol from fermentation broths obtained through the glycerol fermentation process. The developed method was found to be simple and efficient for the isolation and purification of butan-1-ol from the other components in the fermentation mixture....
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Vanadium toxicity in chickpea (Cicer arietinum L.) grown in red soil: Effects on cell death, ROS and antioxidative systems
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Bezpieczne wymiarowanie ścinania ze zmiennym kątem THETA w kratownicach zastępczych według norm EC:2003, DIN:2003, PN:2002
PublikacjaPraca przedstawia zagadnienie wymiarowania elementów żelbetowych na ścinanie według zmodyfikowanej kratownicy Morscha, zamieszczonej w normach: europejskiej, niemieckiej i polskiej. Podano praktyczne wnioski odnośnie bezpiecznego przyjmowania kąta THETA, odwzorowującego nachylenie myślowo wydzielonych betonowych krzyżulców ściskanych.
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Możliwości zastosowań, potencjalne źródła oraz ewolucja technologiczna sposobu otrzymywania trehalozy ze szczególnym uwzględnieniem enzymu syntazy trehalozy [EC 5.4.99.16]
PublikacjaJedna z wiodących gałęzi współczesnej biotechnologii opiera się na produkcji białek – przede wszystkim enzymów. Są one powszechnie wykorzystywane: od przemysłu chemicznego poprzez przemysł spożywczy aż po medycynę i życie codzienne (czy ktoś wyobraża sobie w dzisiejszych czasach proszek do prania „bez enzymu”). Przed rozwojem nowoczesnych metod biologii molekularnej i inżynierii genetycznej pozyskiwano interesujące substancje z...
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Wstępna ocena warunków pracy łożysk ślizgowych turbiny parowej tg2 i ich wpływu na stan dynamiczny turbozespołu EC Gdańsk
PublikacjaGłównym celem ekspertyzy była wstępna analiza możliwości poprawy stanu dynamicznego turbozespołu TG2 pracującego w EC Gdańsk poprzez poprawę własności dynamicznych łożysk. Sformułowano przyczyny wywołujące drgania czopa w łożysku nr 1. Opracowano zalecenia i wymagania związane z planowaną modernizacją łożysk.
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Nursing standard (Royal College of Nursing (Great Britain) : 1987)
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The conducted immunity test of an AC adaptor in accordance with EMC standards
Dane BadawczeThe dataset presents a result of measurements that are a part of immunity tests to conducted disturbances, induced by radio-frequency fields. The immunity tests were carried out on the mains cable of the ac adaptor PHILIPS DC power supply SBC 6654. Tests of immunity of electronic systems to conducted disturbances in the frequency range from 150 kHz...
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Embedded gas sensing setup for air samples analysis
PublikacjaThis paper describes a measurement setup (eNose) designed to analyze air samples containing various volatile organic compounds (VOCs). The setup utilizes a set of resistive gas sensors of divergent gas selectivity and sensitivity. Some of the applied sensors are commercially available and were proposed recently to reduce their consumed energy. The sensors detect various VOCs at sensitivities determined by metal oxide sensors’ technology...
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Concurrent DNA Copy-Number Alterations and Mutations in Genes Related to Maintenance of Genome Stability in Uninvolved Mammary Glandular Tissue from Breast Cancer Patients
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Destabilization of β‐Hemocyanin from Helix pomatia in Presence of Choline Amino Acids Results in Improved Cell Specificity and Cytotoxicity against Human Breast Cancer
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Radiation-induced Changes in Levels of Selected Proteins in Peripheral Blood Serum of Breast Cancer Patients as a Potential Triage Biodosimeter for Large-scale Radiological Emergencies
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