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Wyniki wyszukiwania dla: NOSOCOMIAL INFECTION
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Transcriptomic Effects of Estrogen Starvation and Induction in the MCF7 Cells. The Meta-analysis of Microarray Results
PublikacjaEstrogen is one of the most important signaling molecules which targets a number of genes. Estrogen levels regulate cell proliferation and a plethora of metabolic processes, which may interfere with a range of medical conditions and drug metabolism. The MCF7 breast cancer cell line, expressing the estrogen receptor α, is a well-studied model of cellular answer to estrogen. The aim of this study was to characterize transcriptomic...
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Can Inflation Forecast and Monetary Policy Path be Really Useful? The Case of the Czech Republic
PublikacjaProducing and revealing inflation forecast is belie ved to be the best way of implementing a forward-looking monetary policy. The article focuses on inflation forecast targeting (IFT) at the Czech National Bank (CNB) in terms of its efficiency in shaping consumers’ inflation expectations. The goal of the study is to verify the accuracy of the inflation forecasts, and their influence on inflation...
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3D Machine Vision System for Inspection of Contact Strips in Railway Vehicle Current Collectors
PublikacjaConstruction and technical condition of current collectors is crucial to reliability and safety of railway transportation. According to the Technical Specifications for Interoperability railway vehicles in the European Union should be equipped with carbon contact strips. Excessive wear or defects of contact strips degrade the capability of undisturbed power transmission, cause faster wear of contact wire, and can even result in...
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Model-Free Controller Tuning Based on DFT Processing: Application to Induction Motor Drives
PublikacjaIn this paper, we present a new approach based on discrete Fourier transform (DFT) analysis for controller tuning of the closed-loop system with unknown plant. The DFT analysis is used to process the closed-loop measurements collected online to derive the frequency response of an initial closed-loop system that does not provide a good performance. Based on the closed-loop frequency response data, we propose two methods for tuning PID...
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Current-based higher-order spectral covariance as a bearing diagnostic feature for induction motors
PublikacjaConducting the diagnosis of induction motors remotely by analyzing the supply current is an attractive prospect with the lack of access to the engine. Currently, there is no solution, based on analysis of the current, the credibility of which would allow its use in industry. The statistics of bearing failures in induction motors indicate that they constitute more than 40% of induction motor damage, therefore, bearing diagnosis...
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Induction of chirality in 4,4'-azopyridine by halogen-bonding interaction with optically active ditopic donors
PublikacjaOptically active ditopic halogen bond donors bearing two 4-iodotetrafluorophenyl groups were obtained by reaction of chiral diols with iodopentafluorobenzene. Co-crystallization of these donors with anti-4,4′-azopyridine afforded binary complexes containing infinite chains of the alternating component molecules connected by halogen bonds. The solid state CD measurements confirmed that complexation induces optical activity of the...
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CONSUMERS’ APPROACH TO THE CREDIBILITY OF THE INFLATION FORECASTS PUBLISHED BY CENTRAL BANKS: A NEW METHODOLOGICAL SOLUTION
PublikacjaModern monetary policy focuses on credibility and shaping inflation expectations. In keeping with the concept of inflation forecast targeting, the inflation forecasts published by central banks play a crucial role in the instrument rate decision-making process and may be treated as a specific intermediate target. This study proposes an inflation forecast credibility index, the scope of which is narrowed to non-specialists’ approach...
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Novel condition monitoring of induction motor bearings via motor current signature analysis
PublikacjaThe paper authors are researching the assessment of bearing conditions in induction motors. The methods developed by the authors are based on measurements and analysis of the motor supply current, which is particularly attractive in the absence of access to the engine. The article provides an overview of selected methods of induction motor bearings diagnostic based on Motor Current Signature Analysis (MCSA). However, there is no...
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Sensorless Rotor Position Estimation of Doubly-Fed Induction Generator Based on Backstepping Technique
PublikacjaThis paper proposes a speed observer algorithm for the sensorless control of a doubly-fed induction generator based on classical adaptive backstepping technique. The sensorless control is shown using classic stator field oriented control which is used to active and reactive power control. Performance of the proposed algorithm of a speed observer is validated by simulation and experimental results obtained using a small-rating generator...
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Speed observer of induction machine based on backstepping and sliding mode for low‐speed operation
PublikacjaThis paper presents a speed observer design based on backstepping and slidingmode approaches. The inputs to the observer are the stator current and thevoltage vector components. This observer structure is extended to the integra-tors. The observer stabilizing functions contain the appropriate sliding surfaceswhich result from the Lyapunov function. The rotor angular speed is obtainedfrom the non‐adaptive formula with a sliding...
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Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
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When all we have is not enough: a search for the optimal method of quantifying inflation expectations
PublikacjaAlthough inflation expectations are pivotal variables for central banks, they are not directly observable. Therefore, central banks use qualitative survey results to proxy consumer expectations, and their quantification in this manner is often criticized. In this study, we investigate and identify an optimal quantification procedure for survey results based on a set of regression and probabilistic models. Specifically, we seek...
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Non-Adaptive Rotor Speed Estimation of Induction Machine in an Adaptive Full-Order Observer
PublikacjaIn the sensorless control system of an induction machine, the rotor speed value is not measured but reconstructed by an observer structure. The rotor speed value can be reconstructed by the classical adaptive law with the integrator. The second approach, which is the main contribution of this paper, is the non-adaptive structure without an integrator. The proposed method of the rotor speed reconstruction is based on an algebraic...
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Deep slot effect in the squirrel-cage induction motors with scalar (V/F) control
PublikacjaQualitative characteristics of the electrical drive considerably depend on identification accuracy of math model parameters. In particular, it is depend on detection accuracy of stator active resistance r1 that is used in calculation of flux linkages, rotary speed in sensorless control systems. Paper provides analysis of influence of stator deep slot effect to stator active resistance value
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Speed Observer Structure of Induction Machine Based on Sliding Super-Twisting and Backstepping Techniques
PublikacjaThis paper presents an analysis of the two speed observer structures which are based on the backstepping and sliding super twisting approach. The observer stabilizing functions result from the Lyapunov theorem. To obtain the observer tuning gains the observer structure is linearized near the equilibrium point. The rotor angular speed is obtained from non-adaptive dependence. In the sensorless control system structure the classical...
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Tetrahydroquinolinone derivatives exert antiproliferative effect on lung cancer cells through apoptosis induction
PublikacjaThe anticancer properties of quinolones is a topic of interest among researchers in the scientific world. Because these compounds do not cause side effects, unlike the commonly used cytostatics, they are considered a promising source of new anticancer drugs. In this work, we designed a brief synthetic pathway and obtained a series of novel 8-phenyltetrahydroquinolinone derivatives functionalized with benzyl-type moieties at position...
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Lithium ion insertion into poly(3,4-ethylenedioxythiophene) films from propylene carbonate electrolytes.
PublikacjaPolimerowa matryca złożona z poli(3,4-etylenodioksytiofenu z poli(styrenosulfonianem) otrzymana została na drodze syntezy elektrochemicznej. Transport jonowy w matrycy polimerowej w kontakcie z węglanem propylenu zawierającym LiClO4 został scharakteryzowany za pomocą metody impedancji ac oraz chronowoltoamperometrii. Wyznaczono przewodność jonową matrycy oraz efektywne współczynniki dyfuzji dla kationu Li+. Wielkości te...
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Induction of apoptosis by triazoloacridinone derivative - C-1533 in HL60 and MOLT4 human leukemia cells.
PublikacjaPrzeprowadzone badania miały na celu określenie zdolności triazoloakrydonu C-1533 do indukcji śmierci komórek nowotworowych MOLT4 i HL60 na drodze apoptozy. Badanie zjawiska apoptozy przeprowadzono z wykorzystaniem techniki cytofluorymetrii przepływowej, mikroskopii fluorescencyjnej i elektroforezy agarozowej. Badania wykazały, że zarówno w komórkach MOLT4 jak i HL60, spadek mitochondrialnego potencjału błonowego oraz translokacja...
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Infection and Drug Resistance
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JOURNAL OF INFECTION AND CHEMOTHERAPY
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INFECTION GENETICS AND EVOLUTION
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Empirical Versus Targeted Treatment of Helicobacter pylori Infections in Southern Poland According to the Results of Local Antimicrobial Resistance Monitoring
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Particulate Emissions from European Vehicles Featuring Direct Injection Spark Ignition Engines Tested Under Laboratory Conditions
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Systematic review of the effect of D‑mannose with or without other drugs in the treatment of symptoms of urinary tract infections/cystitis (Review)
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Identification of antigen Ag43 in uropathogenic Escherichia coli Dr+ strains and defining its role in the pathogenesis of urinary tract infections
PublikacjaUrinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are among the most common bacterial infectious diseases in the developed world. The urovirulence of UPEC is mainly associated with the surface-exposed fimbrial adhesins and adhesins of the autotransporter (AT) family. The best studied of theses proteins is antigen 43 (Ag43) mediating cell aggregation, adhesion and biofilm development as the causes of...
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Three-step stacking by field-enhanced sample injection, sweeping, and micelle to solvent stacking in capillary electrophoresis: Anionic analytes
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Three-step stacking of cationic analytes by field-enhanced sample injection, sweeping, and micelle to solvent stacking in capillary electrophoresis
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In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections
PublikacjaWe presented in vitro studies of antimicrobial activity of Gly-His-Lys conjugates that are important point in preliminary biological evaluation of their potential application in skin and tissue therapy. The novel compounds include the conjugation of fatty acids with a modification of the amino acid sequence in the primary structure of Gly-His-Lys.
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Investigation of Wood Flour Size, Aspect Ratios, and Injection Molding Temperature on Mechanical Properties of Wood Flour/Polyethylene Composites
PublikacjaIn the present research, wood flour reinforced polyethylene polymer composites with a coupling agent were prepared by injection molding. The effects of wood flour size, aspect ratios, and mold injection temperature on the composites’ mechanical properties were investigated. For the preparation of the polymer composites, five different formulations were created. The mechanical properties including tensile strength and the modulus,...
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Isolation of Bacteriocin-producing Staphylococcus spp. Strains from Human Skin Wounds, Soft Tissue Infections and Bovine Mastitis
PublikacjaA collection of 206 Staphylococcus spp. isolates was investigated for their ability to produce compounds exhibiting antistaphylococcal activity. This group included Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus xylosus strains recovered from bovine mastitis (n = 158) and human skin wounds and soft tissues infections (n = 48). Production of substances with antimicrobial activity was observed in six strains. Five...
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Direct injection liquid chromatography-mass spectrometry (DI-LC-MS) analysis for rapid lipidomic profiling of extracellular vesicles
PublikacjaExtracellular vesicles (EVs) are small, spherical particles produced by eukaryotic and prokaryotic cells, surrounded by a bilayer membrane and carrying various bioactive molecules, such as proteins, surface receptors, membrane and soluble proteins, lipids, and nucleic acids. EVs are of substantial interest because of their important roles in cell communication, epigenetic regulation and possible application in disease diagnosis...
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Renal and Inflammation Markers—Renalase, Cystatin C, and NGAL Levels in Asymptomatic and Symptomatic SARS-CoV-2 Infection in a One-Month Follow-Up Study
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Use of broad-spectrum antibiotics in children diagnosed with multisystem inflammatory syndrome temporarily associated with SARS-CoV-2 infection in Poland: the MOIS-CoR study
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Analysis of induction of DNA DSBs on telomeres in A549 cells
Dane BadawczeData consist of an analysis of DNA DSBs on telomeres. A549 were treated with compounds (TXT4, MTX, DMSO) at IC90 concentration for the indicated time. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss)....
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Induction of immune responses in sheep by vaccination with liposome-entrapped DNA complexes encoding Toxoplasma gondii MIC3 gene
PublikacjaToxoplasma gondii is a parasite that has been extensively studied due to its medical and veterinary importance in terminating pregnancies. Consequently, a satisfactory vaccine is required to control itsadverse effects on pregnant animals. The microneme protein, MIC3, is a major adhesion protein that binds to the surface of host cells and parasites, and is therefore a potential vaccine against T. gondii.The viability of MIC3 as...
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Smart Virtual Product Development (SVPD) System to Support Product Inspection Planning in Industry 4.0
PublikacjaThis paper presents the idea of supporting product inspection planning process during the early stages of product life cycle for the experts working on product development. Aim of this research is to assist a collaborative product development process by using Smart Virtual Product Development (SVPD) system, which is based on Set of Experience Knowledge Structure (SOEKS) and Decisional DNA (DDNA). The proposed system is developed...
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Application of Feedback Linearization for Air Gap Flux Control of Induction Motor in the Field Weakening Region
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Comparison of induction motor bearing diagnostic test results through vibration and stator current measurement
PublikacjaThe paper discusses results of tests performed by authors, related to the angine bearings diagnostic using vibration and stator current measurements. The paper contains the description of an automatic measurement system, developed for measurement of those harmonics and processing that to obtain bearing diagnostic information. System was tested on objects with intentionally made defects in bearings, results of this test was also...
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Public Perception of the Risks Associated with Infectious Diseases in Poland: Ebola and Influenza and Their Impact on the Attitude to Vaccination
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Applications of calcium electroporation to effective apoptosis induction in fibrosarcoma cells and stimulation of normal muscle cells
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Susceptibility of the LLC Resonance Generator for Induction Heating on Changes in Load Parameters Caused by Heating the Charge
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Simplified simulation technique of rotating, induction heated, calender rolls for study of temperature field control
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Application of hidden Markov models to eye tracking data analysis of visual quality inspection operations
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Old-timer Vehicle - Braking Efficiency Measurement at Vehicle Inspection Stations and Roadworthiness Validity Certificate.
PublikacjaObtaining the Roadworthiness Validity Certificate for an old-timer vehicle involves an appropriate test performance, namely, "Old-timer Vehicle Technical Specification Compliance Test". It seems obvious that this kind of test should include a considerable checklist, however, the current legal regulations connected with this test are not specific enough. One of the certificates issued on this test results is "Old-timer Vehicle Technical...
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Chromatographic lipophilicity determination using large volume injections of the solvents non-miscible with the mobile phase
PublikacjaA new perspective in the lipophilicity evaluation through RP-HPLC is permitted by analysis of the retentionfactor (k) obtained by injecting large volumes of test samples prepared in solvents immiscible withmobile phase. The experiment is carried out on representative groups of compounds with increasedtoxicity (mycotoxins and alkaloids) and amines with important biological activity (naturally occurringmonoamine compounds and related...
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Analysis of loading history influence on fatigue and fracture surface parameters using the method of induction trees
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Positive electrostatic therapy of metastatic tumors: selective induction of apoptosis in cancer cells by pure charges
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Phenethyl Isothiocyanate Inhibits Shiga Toxin Production in Enterohemorrhagic Escherichia coli by Stringent Response Induction
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
Publikacjanthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones. BS-154, the most potent derivative, had IC50 values close to 1 nM, however, it was toxic in animal studies. Here, we characterize another...
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Fast Real-Time RDFT- and GDFT-Based Direct Fault Diagnosis of Induction Motor Drive
PublikacjaThis paper presents the theoretical analysis and experimental verification of a direct fault harmonic identification approach in a converter-fed electric drive for automated diagnosis purposes. On the basis of the analytical model of the proposed real-time direct fault diagnosis, the fault-related harmonic component is calculated using recursive DFT (RDFT) and Goertzel DFT (GDFT), applied instead of the full spectrum calculations...