Search
Filters
total: 8362
filtered: 3184
-
Catalog
- Publications 3184 available results
- Journals 16 available results
- Publishing Houses 5 available results
- People 433 available results
- Projects 18 available results
- Research Teams 4 available results
- Research Equipment 1 available results
- e-Learning Courses 2469 available results
- Events 85 available results
- Open Research Data 2147 available results
Chosen catalog filters
displaying 1000 best results Help
Search results for: phase ii enzymes
-
Beta-Galactosidases of Pseudoalteromonas sp. – Characteristics and application for lactose hydrolysis and galactopyranosides synthesis
PublicationBeta-galactosidase [EC 3.2.1.23] is an enzyme that catalyzes the hydrolysis of O-glycosidic linkages in galactosides. It has biotechnological applications in the dairy industry for the production of milk with a low content of lactose and galactooligosacharides for use in healthy food. The transgalactosylation activity of beta-galactosidase can be used in the synthesis of alkyl galactopyranosides. Due to the fact that conditions of...
-
In Situ Random Microseeding and Streak Seeding Used for Growth of Crystals of Cold-Adapted beta-D-Galactosidases: Crystal Structure of betaDG from Arthrobacter sp. 32cB
PublicationThere is an increasing demand for cold-adapted enzymes in a wide range of industrial branches. Nevertheless, structural information about them is still scarce. The knowledge of crystal structures is important to understand their mode of action and to design genetically engineered enzymes with enhanced activity. The most difficult task and the limiting step in structural studies of cold-adapted enzymes is their crystallization,...
-
Inhibiting activity of HIV-1: protease, reverse transcriptase and integrase all together by novel compounds using computational approaches (flexible and rigid docking)
PublicationAcquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus type 1 (HIV-1) infection, is one of the most challenging diseases in recent decades. Nevertheless the shortcomings of chemical drugs such as toxicity, lack of curative effects, the search for more potent anti-HIV agents have been focused in our study. In current study, novel scaffold was designed having a benzyl and imidazole in it which are very...
-
Peptidoglycan hydrolases - potential weapons against Staphylococcus aureus
PublicationBacteria of the genus Staphylococcus are common pathogens responsible for a broad spectrum of human and animal infections and belong to most important etiological factors causing food poisoning. Because of rapid increase in prevalence of isolation of staphylococci resistant to many antibiotics, there is an urgent need for development of new alternative chemotherapeutics. A number of studies have recently demonstrated the strong...
-
Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublicationPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
-
Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors
PublicationThe chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...
-
Synthesis of phosphono and phosphate derivatives of hydroxyimino-D-alditols as new potential antifungal agents
PublicationIn search for new effective we antyfungals we focus on two enzymes involved in biosynthesis of the fungal cell wall. The first enzyme is glucosamine-6-phosphate (GlmS), which catalyzes transformation of D-fructose-6-phosphate (Fru-6P) to D-glucosamine-6-phodphate (GlcN-6P) in the chitin biosynthesis pathway. The second enzyme is phosphomannose isomerase (PMI) repored to play a crucial role in biosynthesis of many mannosylated structures,...
-
Elucidating the impact of enzymatic modifications on the structure, properties, and applications of cellulose, chitosan, starch and their derivatives: a review
PublicationPolysaccharides, as one of the most prominent natural biopolymers, display numerous biological activities and industrial applications. Nevertheless, some polysaccharides lack biological properties or display weak biological activities. Besides, practical usages of polysaccharides still remain challenging because of their poor solubility and inappropriate hydrophilic/hydrophobic balance. Hence, enzymatic or chemical modifications...
-
The influence of selenium addition during germination of Brassica seeds on health-promoting potential of sprouts
PublicationThe correlation among selenium uptake, the content of bioactive compounds in sprouts, and biological activities triggered in cultured human cells by sprout extracts was investigated. Seeds of Brassica crops and rye were treated with SeO2 water solution. The selenium levels in sprouts increased from 1.0-4.1 to 53.3-382 μg/g dw with no influence on plant physiology according to the indices used. Neither the composition of glucosinolates...
-
Solvation numbers of manganese(II) and zinc(II) perchlorates in methanol obtained from volumetric and compressibility properties
PublicationZmierzono gęstości roztworów nadchloranów manganu(II) i cynku(II) w metanolu w temperaturach: 283.15, 288.15, 293.15, 298.15, 303.15, 308.15, 313.15 K. Ponadto wyznaczono szybkości rozchodzenia się dźwięku w badanych roztworach w 298.15 K. Uzyskane wielkości pozwoliły na obliczenie pozornych objętości molowych oraz pozornych molowych ściśliwości adiabatycznych elektrolitów w metanolu. Oszacowane wielkości graniczne wykorzystane...
-
Przydatność białka rybiego w postaci kolagenu lub żelatyny oraz polisacharydu - kapa-karagenu do wytwarzania aktywnych opakowań biodegradowalnych = Usefulness of fish collagen, gelatin and carrageenan for preparation of active biodegradable packages
PublicationSummary - The possibility of use of protein films made of fish collagen or gelatin as well as polysaccharide carrageenan films as carriers of enzymes (lysozyme or lysostaphyne), for preparation of microbiologically active packages, was investigated. It was found that crosslinking of such systems with N-[3(dimethylamino)propyl]-N'-ethylcarboimide (EDC) does not influence the activity of lysozyme immobilized in the films (Table 1)....
-
Molecular Targets for Anticandidal Chemotherapy
PublicationA relatively small number of anticandidal chemotherapeutics used in clinical practice is at least in part consequence of a limited number of their molecular targets: ergosterol in the membrane, lanosterol demethylase, b(1!3) glucan synthase, and DNA/RNA biosynthesis. Much more potential novel targets have been revealed by the comparative genomic studies identifying essential genes unique for Candida albicans or resulted from recognition...
-
The Caucasian flora: a still-to-be-discovered rich source of antioxidants
PublicationCellular redox homeostasis is a state of balance between the formation of Usually Reactive Oxygen and / or Nitrogen Species (ROS/RNS), endogenous antioxidant defence systems, and exogenous dietary antioxidants. The disturbance of redox homeostasis, by the overproduction of endogenous ROS/RNS, may increase the risk of development of so-called civilisation diseases. The solution seems to be either the increased production of endogenous...
-
A standardised static in vitro digestion method suitable for food – an international consensus
PublicationSimulated gastro-intestinal digestion is widely employed in many fields of food and nutritional sciences, as conducting human trials are often costly, resource intensive, and ethically disputable. As a consequence, in vitro alternatives that determine endpoints such as the bioaccessibility of nutrients and non-nutrients or the digestibility of macronutrients (e.g. lipids, proteins and carbohydrates) are used for screening and building...
-
INFOGEST static in vitro simulation of gastrointestinal food digestion
PublicationDeveloping a mechanistic understanding of the impact of food structure and composition on human health has increasingly involved simulating digestion in the upper gastrointestinal tract. These simulations have used a wide range of different conditions that often have very little physiological relevance, and this impedes the meaningful comparison of results. The standardized protocol presented here is based on an international consensus...
-
Bovine Serum Albumin – Hydroxyapatite Nanoflowers as Potential Local Drug Delivery System of Ciprofloxacin
PublicationIntroduction: Hybrid nanoflowers are structures consisting of organic (enzymes, proteins, nucleic acids) and inorganic components (mostly metal phosphates) with a flower-like hierarchical structure. Novel hybrid nanoflowers based on bovine serum albumin (BSA) and hydroxyapatite (HA) were obtained and characterized. Study on BSA-HA nanoflowers as potential drug delivery system is reported for the first time. Methods: Embedding ciprofloxacin...
-
Modulation of carcinogen metabolizing cytochromes p450 in rat liver and kidney by cabbage and sauerkraut juices: comparison with the effects of indole-3-carbinol and phenethyl isothiocyanate
PublicationThis study investigated the effect of raw cabbage and sauerkraut juices on the activity and expression of CYP1A1, 1A2, 1B1 and 2B in Wistar rat liver and kidney. The results were compared with those of two commercially available products of glucosinolates degradation: indole-3-carbinol (I3C) and phenethyl isothiocyanate (PEITC). Significant differences in the effect of the cabbage juices as well as I3C and PEITC between the liver...
-
Thermal analysis of bis(tetraethylammonium) tetrachloroferrate(II)
PublicationBadano dekompozycję termiczną związków bis(tetraethylammonium) tetrachloroferrate(II). Stosowano następujące metody badawcze: TG-FTIR, TG-MS i DTA. Pomiary przeprowadzono w atmosferze obojętnej w zakresie temperatur od 293 K do 1073 K. Stałe produkty dekompozycji identyfikowano metodą spektroskopii w podczerwieni, spektroskopii Mössbauera oraz metodą dyfrakcji promieniowania rentgenowskiego. Przedyskutowano wpływ stopnia utlenienia...
-
Cis-Dichloridobis(ethyldiphenylphosphine-ĸP)platinum(II)
PublicationTytułowy związek został otrzymany w reakcji K2PtCl4 z PEtPh2. Atom platyny wykazuje typową dla Pt(II) koordynację płasko-kwadratową. W powyższej metodzie otrzymuje się wyłącznie izomer cis. Upakowanie cząsteczek w krysztale wzmocnione jest poprzez słabe oddziaływania międzycząsteczkowe C-H...Cl.
-
Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublicationEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
-
Chlorido(4-morpholinecarbodithioato-k2S,S')(triphenylphosphine)nickel(II)
PublicationPrzeprowadzono syntezę oraz wyznaczono strukturę związku [Ni(C5H8NOS2)Cl(C18H15P)]. Tytułowy kompleks chloro(morfolinoditiokarbaminiano-S,S')(trifenylofosfina)-nikiel(II) posiada nieznacznie zniekształcony płaski kwadratowy rdzeń NiClS2P.
-
FPGA implementation of reverse residue conversion based on the new Chinese Remainder Theorem II- Part II,- Experimantal results
PublicationW pracy opisano realizację sprzętową konwertera z systemu resztowego do systemu binarnego. Konwerter jest oparty na nowej formie chińskiego twierdzenia o resztach CRT II. Teoretyczne aspekty takiej konwersji przedstawiono w części I. Implementację konwertera wykonano w środowisku Xilinx FPGA. Zaprezentowano ogólną architekturę konwertera, a także opisano realizację wybranych bloków. Podano ilość koniecznych zasobów sprzętowych...
-
Hexakis(1-methylimidazole-kN3)iron(II) dichloride dihydrate
PublicationTytułowy związek, [Fe(C4H6N2)6]Cl2.2H2O jest izostrukturalny z odpowiednimi związkami Co, Ni i Ru. W kompleksowym kationie żelazo(II) jest koordynowane oktaedrycznie przez sześć ligandów 1-metyloimidazolowych. Jon ujemny jest agregatem dwóch jonów chlorkowych i dwóch cząsteczek wody połączonych wiązaniami wodorowymi.
-
Novel application of terminal restriction fragments length polymorphism method (t-RFLP) for identification of six clinically important Candida sp.
PublicationTerminal restriction fragments length polymorphism method (t-RFLP) is a modified classical RFLP method. The main difference is based on carrying out PCR using a fluorescently labeled primer or primers. The result of such modification is that after digestion of amplicons only terminal fragments of PCR product (containing fluorescent dye) are visualized. T-RFLP method has found application in environmental microbiology and epidemiology....
-
Organic solvents aggregating and shaping structural folding of protein, a case study of the protease enzyme
PublicationLow solubility of reactants or products in aqueous solutions can result in the enzymatic catalytic reactions that can occur in non-aqueous solutions. In current study we investigated aqueous solutions containing different organic solvents / deep eutectic solvents (DESs) that can influence the protease enzyme's activity, structural, and thermal stabilities. Retroviral aspartic protease enzyme is responsible for the cleavage of the...
-
(3,5-Dimethylpyridine)bis(tri-tert-butoxysilanethiolato)cadmium(II)
PublicationTytułowy związek jest molekularnym, heteroleptycznym tiolanem kadmu zawierającym jako dodatkowy ligand 3,5-dimetylopirydynę. Jon kadmu(II) znajduje się w centrum bipiramidy o podstawie trójkątnej, utworzonej przez 5 atomów - 2 atomy siarki, 2 atomy tlenu i jeden atom azotu. Między cząsteczkami kompleksu upakowanymi w krysztale nie ma oddziaływań innych niż oddziaływania van der Waalsa.
-
Gates of Enzymes
Publication -
Cloning and characterization of a novel cold-active glycoside hydrolase family 1 enzyme with beta-glucosidase, beta-fucosidase and beta-galactosidase activities.
PublicationBackground: Cold-active enzymes, sourced from cold-adapted organisms, are characterized by high catalytic efficiencies at low temperatures compared with their mesophilic counterparts, which have poor activity. This property makes them advantageous for biotechnology applications as it: (i) saves energy costs, (ii) shortens the times for processes operated at low temperatures, (iii) protects thermosensitive substrates or products...
-
Impact of high-pressure processing on the bioactive compounds of milk - A comprehensive review
PublicationHigh-pressure processing (HPP) is a promising alternative to thermal pasteurization. Recent studies highlighted the effectivity of HPP (400–600 MPa and exposure times of 1–5 min) in reducing pathogenic microflora for up to 5 logs. Analysis of modern scientific sources has shown that pressure affects the main components of milk including fat globules, lactose, casein micelles. The behavior of whey proteins under HPP is very important...
-
Bee Pollen and Bee Bread as a Source of Bacteria Producing Antimicrobials
PublicationThe principal objective of the study was the isolation and identification of bacteria that are present in mature bee bread (BB) and dried (ready for selling and consumption) bee pollen (BP). Obtained isolates were screened for their potential to inhibit select human pathogenic bacteria and their ability to produce enzymes of particular industrial importance. Four and five samples of BP and BB, respectively, were used for the study....
-
Electrochemicalsynthesis of 3D nano-/micro-structured porous polypyrrole
PublicationIn this work, electrosynthesis of electroactive, 3D nano-/micro-structured porous polypyrrole film is presented. The PPy film was synthesized potentiostatically in a one-step process from aqueous solution of pyrrole and lithium perchlorate. The growth mechanism of such structure included: the formation of typical globular PPy film, followed by the formation of the PPy fibers, which then took part in the formation of 3D highly porous...
-
Human carnosinases: A brief history, medicinal relevance, and in silico analyses
PublicationCarnosine, an endogenous dipeptide, has been found to have a plethora of medicinal properties, such as antioxidant, antiageing, and chelating effects, but with one downside: a short half-life. Carnosinases and two hydrolytic enzymes, which remain enigmatic, are responsible for these features. Hence, here we emphasize why research is valuable for better understanding crucial concepts like ageing, neurodegradation, and cancerogenesis,...
-
Heteroleptic tri-tert-butoxysilanethiolate complexes of manganese(II) - thermal studies
PublicationThe thermal behavior of Mn(II) silanethiolate series [Mn(SR)2L(MeOH)n], where R=SSi(OBut)3, L=heterocyclic nitrogen base and n=0, 1 or 2 has been comparatively investigated using differential scanning calorimetry (DSC), thermogravimetry (TG) and TG-infrared spectoscopy (IR) techniques. The TG curves indicate the differences in the thermal decomposition due to presence of distinct N-donor ligands and labile MeOH molecules coordinated...
-
Chlorido(1-pyrrolidinecarbodithioato-k2S,S')(triphenylphosphine)nickel(II)chloroform hemisolvate
PublicationTytułowy kompleks chloro(1-pirolidynoditiokarbaminiano-S,S')(trifenylofosfina)-nikiel(II), będący hemisolwatem chloroformu zawiera płaski rdzeń o składzie NiClS2P. Molekuły chloroformu oddziałują z kompleksem poprzez słabe wiązania C-H...S.
-
Oznaczanie tlenu – od metody Winklera do czujników enzymatycznych (Determination of oxygen – from Winkler Method to enzymatic sensor)
PublicationMonitoring of dioxygen levels is of utmost importance from the view-point of life processes, medical diagnostics, nutrition and chemical industries. In all these measurements both low and high levels of this element are important. The common methods for the determination of dioxygen are the Winkler method, Clark electrode and pulsoxymeters. A new, already strong field of research can be now recognized – the development of miniaturized...
-
(2,2'-bipyridine)bis(tri-tert-butoxysilanethiolato-κ2O,S)cadmium(II)
PublicationW pracy przedstawiono strukturę heteroleptycznego kompleksu silanotiolanu kadmu(II) z bipirydylem, który krystalizuje w układzie jednoskośnym, w grupie przestrzennej C2/c. Rdzeń kompleksu CdS2O2N2 ze względu na chelatujący charakter reszt silanotiolanowych posiada zniekształconą geometrię oktaedryczną.
-
Tris(1,10-phenanthroline-k2N,N')iron(II) dichloride methanol hexasolvate
PublicationTytułowy związek składa się z kompleksowego kationu, w którym do żelaza(II) oktaedrycznie koordynują trzy bidentne ligandy fenantrolinowe oraz dwóch jednoujemnych agregatów: [Cl(MeOH)2](-) i [Cl(MeOH)4](-), gdzie jony chlorkowe i cząsteczki metanolu są powiązane wiązaniami wodorowymi.
-
Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking
PublicationHerein, we present the synthesis and crystal structures determination of five 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives containing halogen atoms, 6a–e, which may be used as an excellent mimic of steroids in the drug development process. Good quality crystals obtained for all of the synthesized compounds allowed the analysis of their molecular structures. Subsequently, the determined crystal structures were used to calculate...
-
Bis(tri-tert-butoxysilanethiolato-kS)bis(pyrrolidine-kN)cobalt(II)
PublicationReakcja [Co{SSi(OtBu)3}2(NH3)]2 z pyrrolidyną prowadzi do otrzymania kompleksu [Co(C12H27O3SSi)2(C4H9N)2], gdzie atom kobaltu(II) jest koordynowany przez dwie reszty silanotiolanowe i dwie reszty pyrrolidyny. Specyficzne przestrzenne ułożenie wszystkich ligandów dodatkowo daje możliwość utworzenia dwóch wewnątrzcząsteczkowych wiązań wodorowych N-H***O.
-
Tetrahydrofuran-kO bis(tri-tert-butoxysilanethiolato-k2O,S)chromium(II)
PublicationTytułowy związek jest pierwszym silanotiolanowym kompleksem chromu(II). Atom chromu jest koordynowany przez 0,S-chelatujący tri-tert-butoksysilanotiolanowy ligand oraz dodatkowy ligand - czasteczkę tetrahydrofuranu. Geometrię ligandów wokół atomu chromu można opisać jako piramidę o podstawie kwadratu, z czasteczką tetrahydrofuranu w pozycji wierzchołkowej. Związek ten posiada dwukrotną oś symetrii.
-
Solid-contact lead(II) ion-selective electrodes for potentiometric determination of lead(II) in presence of high concentrations of Na(I), Cu(II), Cd(II), Zn(II), Ca(II) and Mg(II)
PublicationLead and its compounds are a serious threat to the environment. Monitoring of this toxic heavy metal is a driving force for the continuous development of novel lead(II) ionophores to be applied in ion-selective electrodes. In this work a highly selective lead(II) ionophore, namely 25,26,27,28-tetrakis(piperidinylthiocarbonylmethylene)-p-tert-butylcalix[4]arene, was used in solid-contact ion-selective electrodes for determination...
-
Selective transport of Pb(II) across polymer inclusion membrane using imidazole azocrown ethers as carriers.
PublicationZbadano selektywność transportu jonów ołowiu(II) z równomolowych roztworów jonów Zn(II), Cd(II) i Pb(II) przez polimerowe membrany inkluzyjne (PIM) zawierające imidazolowe etery azokoronowe.Wykazano, że polimerowe membrany inkluzyjne z imidazolowymi azokoronami wykazują dużą stabilność, zależną w dużym stopniu od rodzaju jonoforu.
-
Coordination complexes of Mn(II), Co(II), Ni(II), Zn(II) and Cd(II) with histaminol – Crystal structures and formation constants in aqueous solution
PublicationStability constants were determined for a series of coordination complexes of Mn(II), Co(II), Ni(II), Zn(II) and Cd(II) with histaminol in aqueous solution. The tendency of histaminol to form chelate complexes has been confirmed by the isolation of several complex species in the monocrystalline form and determination of their molecular structures.
-
Synthesis and antimicrobial activity of 6-sulfo-6-deoxy-D-glucosamine and its derivatives
Publication6-Sulfo-6-deoxy-D-glucosamine (GlcN6S), 6-sulfo-6-deoxy-D-glucosaminitol (ADGS) and their N-acetyl and methyl ester derivatives have been synthesized and tested as inhibitors of enzymes catalyzing reactions of the UDP-GlcNAc pathway in bacteria and yeasts. GlcN6S and ADGS at micromolar concentrations inhibited glucosamine-6-phosphate (GlcN6P) synthase of microbial origin. The former was also inhibitory towards fungal GlcN6P N-acetyl...
-
3D polypyrrole structures as a sensing material for glucose detection
PublicationIn this work, 3D polypyrrole (PPy) structures as material for glucose detection is proposed. Polypyrrole was electrochemically polymerized on platinum screen-printed electrode from an aqueous solution of lithium perchlorate and pyrrole. The growth mechanism of such PPy structures was studied by ex-situ scanning electron microscopy. Preliminary studies show that studied here PPy film is a good candidate as a sensing material for...
-
RESIDUE ANALYSIS OF ETU AND PTU BY LC/MS
PublicationDithiocarbamates (DTCs) are important organosulfur compounds, which act as inhibitors of metal dependant and sulphydryl enzymes and have a serious consequence on biological systems. They possess variety of applications in agriculture as fungicides, as well as, in the rubber industry as vulcanization accelerators and antioxidants. In this way, DTCs are the main group of fungicides used to control approximately 400 pathogens of more...
-
Characterization of two aminotransferases from Candida albicans
PublicationAminoadipate aminotransferase (AmAA) is an enzyme of α-aminoadipate pathway (AAP) for l-lysine biosynthesis. AmAA may also participated in biosynthesis or degradation of aromatic amino acids and in d-tryptophan based pigment production. The AAP is unique for fungal microorganisms. Enzymes involved in this pathway have specific structures and properties. These features can be used as potential molecular markers. Enzymes catalyzing...
-
Modulation of CYP3A4 activity and induction of apoptosis, necrosis and senescence by the antitumor imidazoacridinone C-1311 in human hepatoma cells
PublicationThere is increasing evidence that the expression level of drug metabolic enzymes affects the final cellular response following drug treatment. Moreover, anti-tumour agents may modulate enzymatic activity and/or cellular expression of metabolic enzymes in tumour cells. We investigated the influence of CYP3A4 overexpression on the cellular response induced by the anti-tumour agent C-1311 in hepatoma cells. C-1311-mediated CYP3A4...
-
Perturbation of cellular functions by topoisomerase II inhibitors: all roads lead to cell death?
PublicationPraca przeglądowa opisuje jakie funkcje mogą ulec zahamowaniu/zmianie pod wpływem działania inhibitorów topoizomerazy typu II w komórkach nowotworowych. W szczególności dyskutujemy jakie zmiany w szlakach sygnalizacji wewnątrzkomórkowej mogą prowadzić do zahamowania wzrostu oraz indukcji różnych rodzajów śmierci komórkowej i czy rodzaj śmierci komórkowej może decydować o skuteczności leków przeciwnowotoworowych, które hamują aktywność...
-
Recurrent potential pulse technique for improvement of glucose sensing ability of 3D polypyrrole
PublicationIn this work, a new approach for using a 3D polypyrrole (PPy) conducting polymer as a sensing material for glucose detection is proposed. Polypyrrole is electrochemically polymerized on a platinum screen-printed electrode in an aqueous solution of lithium perchlorate and pyrrole. PPy exhibits a high electroactive surface area and high electrochemical stability, which results in it having excellent electrocatalytic properties. The...