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Search results for: PH
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Studies on the orientation effect of crystallites and its application to cocrystal screening of selected pharmacologically active compounds
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Phage Therapy—Challenges, Opportunities and Future Prospects
PublicationThe increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly. Phages that selectively infect and kill bacteria are often the only life-saving therapeutic option. Full legalization of this treatment method could help solve the problem of multidrug-resistant infectious diseases on a global scale. The aim of...
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The J-curve phenomenon revisited
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The phenomenon of rurality: the case of Poland
PublicationWieś była przez stulecia źródłem kultury polskiej. Wojny światowe i okres komunistycznego totalitaryzmu przyniosły ogromne straty w dziedzictwie kulturowym wsi. Transformacja ustrojowa i skrajny liberalizm gospodarki przestrzennej powodują dalszą degradację tego dziedzictwa. Podstawowe problemy ochrony dziedzictwa kulturowego wsi to słabość przepisów prawnych, zanik tożsamości kulturowej wsi, brak strategii kształtowania krajobrazu...
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Early stage of critical clusters growth in phenomenological and Molecular Dynamic simulation models
PublicationW artykule opisano wzrost klastrów krytycznych w ramach klasycznego podejścia fenomenologicznego oraz dynamiczno-molekularnego (MD). Została wyprowadzona nowa formuła opisujaca liczbę klastrów krytycznych. Sformułowano równania opisujace wczesne etapy wzrostu kropli o rozmiarach krytycznych. Opisano wyniki symulacji dynamiczno-molekularnych powstawania klastrów w jednorodnej parze przesyconej oraz podano czasowe zmiany rozkładu...
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Various modes of action of dietary phytochemicals, sulforaphane and phenethyl isothiocyanate, on pathogenic bacteria
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Early stage of critical clusters growth in phenomenological and Molecular Dynamic simulation models.
PublicationOpisano proces kondensacji pary wodnej w ujĘciu fenomenologicznymi dynamiczno-molekularnym. Wczesne fazy wzrostu klastra opisano w ramach klasycznej teorii Hertza-Knudsena. Obszernie przedstawiono wyniki symulacji dynamiczno-molekularnych zjawiska kondensacji pary wodnej z jednorodnej fazy gazowej (przebieg powstawania małych klastrów H2O i szybkość wzrostu klastrów ponadkrytycznych).
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Graphene Reinforced Phenolic Foams
PublicationPhenolic foams (PF) belong to the polymeric materials, which are very attractive from the point of many possible applications such as insulation or fire protection materials. This chapter attempts to explain the influence of graphene and graphene derivatives on the phenolic foams. This work briefly presents different graphene nanoparticles introduced to the phenolic foams matrix, in terms of impact on the thermal, mechanical, and...
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Cloning, expression in Komagataella phaffii, and biochemical characterization of recombinant sequence variants of Pseudomonas sp. S9 GDSL-esterase
PublicationTwo recombinant Komagataella phaffii (formerly Pichia pastoris) yeast strains for production of two sequential variants of EstS9 esterase from psychrotolerant bacterium Pseudomonas sp. S9, i.e. αEstS9N (a two-domain enzyme consisting of a catalytic domain and an autotransporter domain) and αEstS9Δ (a single-domain esterase) were constructed. However, only one of recombinant K. phaffii strains, namely Komagataella phaffii X-33/pPICZαestS9Δ,...
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Lipidomics of Staphylococcus aureus – a new insight into the antibiotic resistant phenotype
PublicationStaphylococcus aureus is an aggressive pathogen responsible for a variety of diseases, in cluding life-threatening sepsis. Many strains of these bacteria are resistant to multiple classes of antibiotics, which is a substantial clinical problem in the treatment of S. aureus infections. We developed a comprehensive untargeted lipidomic workflow, including sample preparation, liquid chromatography-quadrupole-time-of-flight mass spectrometry...
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Polymeric metal‐containing ionic liquid sorbent coating for the determination of amines using headspace solid‐phase microextraction
PublicationThis study describes the design, synthesis, and application of polymeric ionic liquid sorbent coatings featuring nickel metal centers for the determination of volatile and semivolatile amines from water samples using headspace solidphase microextraction. The examined polymeric ionic liquid sorbent coatings were composed of two ionic liquid monomers (tetra(3-vinylimidazolium)nickel bis[(trifluoromethyl)sulfonyl]imide [Ni2+(VIM)4]...
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Admission control method based on effective delay for flows using EF PHB.
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Admission control method based on effective delay for flows using EF PHB.
Publication.
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Thermal degradation of polylactic acid (PLA)/polyhydroxybutyrate (PHB) blends: A systematic review
PublicationPolylactic acid (PLA) and polyhydroxybutyrate (PHB) are two biopolyesters obtained from renewable resources like corn or sugar under bacterial fermentation. PLA is the most widely used biopolymer in diverse applications. Addition of PHB to PLA can improves the crystallinity of PLA, and thereby its mechanical strength. However, both PLA and PHB suffer from poor thermal stability, which limits their potential industrial application....
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Methods for evaluation packet delay distribution of flows using Expedited Forwarding PHB.
PublicationArtykuł dotyczy problemu zapewnienia statystycznych gwarancji jakości obsługi dla strumieni czasu rzeczywistego korzystających z Expedited Forwarding Per Hop Behavior (EF PHB) w sieci IP Differentiated Services. Statystyczne podejście do określenia gwarancji jakościowych, oparte na obliczaniu prawdopodobieństwa że opóźnienie pakietów od końca do końca jest większe niż określona wielkość, pozwala lepsze wykorzystanie sieci niż poprzednio...
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Blood equivalent phantom vs whole human blood, a comparative study
PublicationPreclinical research of biomedical optoelectronic devices is often performed with the use of blood phantoms — a simpli¯ed physical model of blood. The aim of this study is the comparison and distinction between blood phantoms as well as whole human blood measurements. We show how the use of such phantoms may in°uence the incorrect interpretation of measured signal. On the other hand, we highlight how the use of blood phantoms enables...
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Bibliografia wybranych przekładów Stanisława Ulaszka [A select bibliography of translations by Stanisław Ulaszek, PhD]
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Bibliografia wybranych przekładów Stanisława Ulaszka [A select bibliography of translations by Stanisław Ulaszek, PhD]
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Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering
PublicationWe present an alternative to the conventional approach, phantoms without scattering nanoparticles, where scattering is achieved by the material itself: spherical cavities trapped in a silicone matrix. We describe the properties and fabrication of novel optical phantoms based on a silicone elastomer polydimethylsiloxane (PDMS) and glycerol mixture. Optical properties (absorption coefficient µa, reduced scattering coefficient µs',...
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Use of optical skin phantoms for calibration of dermatological lasers
PublicationA wide range of dermatological diseases can be efficiently treated using laser heating. Nevertheless, before the new laser is introduced into clinical practice, its parameters and ability to interact with human skin have to be carefully examined. In order to do that optical skin phantoms can be used. Such phantoms closely imitate the scattering and absorption properties of real human skin tissue along with its thermal properties,...
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Bifunctional Opioid/Melanocortin Peptidomimetics for Use in Neuropathic Pain: Variation in the Type and Length of the Linker Connecting the Two Pharmacophores
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The possibility to use multi-walled carbon nanotubes as a sorbent for dispersive solid phase extraction of selected pharmaceuticals and their metabolites: Effect of extraction condition
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In vitro antioxidative and binding properties of phenolics in traditional, citrus and exotic fruits
PublicationMany polyphenols bind proteins, therefore our research was focused on the potential of protein binding to polyphenols of investigated fruits and their health-related effects. The contents of polyphenols and related antioxidant activities of traditional, citrus and exotic fruits were compared. The presence of polyphenols (flavonoids and phenolic acids) in the investigated samples and their interaction with human serum albumin (HSA)...
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Theoretical methods in thermodynamics of condensed phases
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Release and Transport of Toxic, Mobile Organic Compounds (Formaldehyde and Phenols) on an Arctic Glacier
PublicationAs a result of current deglaciation, the chemical cycles of many compounds, including toxic formaldehyde and phenols, are changing. However, the processes by which these chemicals are released have yet to be studied in situ. Here, we quantify fluxes of HCHO and phenols in a glacial catchment within one summer season, obtaining a net release from the glacier of 0.106 · 106 g formaldehyde and 0.255 · 106 g phenols, which can be interpreted...
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The role of a pharmacist in a hospice: a nationwide survey among hospice directors, pharmacists and physicians
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Pharmacoeconomic considerations regarding hospice and palliative care according to pharmacists and hospice managers
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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How to decrease pharmaceuticals in the environment? A review
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Total mercury in great cormorant (Phalacrocorax carbo) and fish in polish sector of Vistula Lagoon
PublicationAnalizowano tkanki miękkie 55 osobników kormorana czarnego oraz wybrane gatunki ryb stanowiące ich pokarm. Badane próbki pochodziły z ekosystemu Zalewu Wiślanego. Zawartość rtęci oznaczono w narządach wewnętrznych kormorana czarnego takich jak: wątroba, nerki, mięśnie, przełyk, żołądek, jelita, tchawica, płuca, mięsień sercowy. Przebadano następujące gatunki ryb: śledź, stynka, karaś, karaś srebrzysty, płoć, lin, jazgarz. Oznaczenia...
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Dietary Isothiocyanates, Sulforaphane and 2-Phenethyl Isothiocyanate, Effectively Impair Vibrio cholerae Virulence
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Central Metal Determines Pharmacokinetics of Chlorophyll-Derived Xenobiotics
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The influence of the time of day on midazolam pharmacokinetics and pharmacodynamics in rabbits
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Influence of Time of Day on Propofol Pharmacokinetics and Pharmacodynamics in Rabbits
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Ice Phenomena in River Mouths
PublicationRiver outlets located in tideless areas are analyzed in this paper. First, ice processes in the St Clair River mouth are presented. The river mouth, called St. Clair Flats is a typical river delta located on the shore of Lake St. Clair. Based on this example ice jam formation in river delta has been analyzed followed by a presentation of the main mechanism of ice jam formation. The Vistula River mouth is a man-made, artificial...
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Molecular mechanism of retention in reversed-phase high-performance liquid chromatography and classification of modern stationary phases by using quantitative structure–retention relationships
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Cavitation Erosion – Phenomenon and Test Rigs
PublicationThe cavitation and cavitation erosion phenomenon have been shortly presented. The main four types of test rigs to investigate the cavitation erosion resistance have been shown. Each type of test design is described and an example of a design is shown. A special attention has been payed to the designs described in the International ASTM Standards: a vibratory design and a cavitating jet cell. There was shown that the design of a...
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Modes of vibrations occuring in the washboarding phenomenon
PublicationW oparciu o współczesną literaturę oraz wyniki badań własnych przedstawiono teorie zjawiska washboarding dla obróbki na pilarkach taśmowych z użyciem wąskich i szerokich pił. Zaprezentowano również wytłumaczenie wspomnianego zjawiska dla przypadku obróbki na pilarkach ramowych. Poprzez analogię do drgań typu chatter (drgania samowzbudne w obróbce metali) zaproponowano nazwy regenerative washboarding, dla drgań samowzbudnych na...
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Isolation and Characterization of Phenol-Degrading Psychrotolerant Yeasts
PublicationIn this study, the potential of selected psychrotolerant yeast strains for phenol biodegradation was studied. From 39 strains isolated from soil and water samples from Rucianka peat bog, three psychrotolerant yeast strains: A011, B021 and L012 showed the ability to phenol degradation. The result shows that all three yeast strains could degrade phenol at 500 mg l-1 and 750 mg l-1 concentration, whereas strains A011 and L012 could...
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Flexible syngas-biogas-hydrogen fueling spark-ignition engine behaviors with optimized fuel compositions and control parameters
PublicationThis paper presents the results research on the optimal fuel compositions and the control parameters of the spark ignition engine fueled with syngas-biogas-hydrogen for the purpose of setting up a flexible electronic control unit for the engine working in a solar-biomass hybrid renewable energy system. In syngas-biogas-hydrogen mixture, the optimal content of hydrogen and biogas is 20% and 30%, respectively. Exceeding these thresholds,...
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Optical processes in YVO4:Eu3+across zircon-to-scheelite phase transition
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Oil spill response planning tool for estimating the recovery capability of mechanical skimming systems potential
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A review of the traditional uses, phytochemistry, pharmacology, and clinical evidence for the use of the genus Alchemilla (Rosaceae)
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Inhibition of protein glycosylation reverses the MDR phenotype of cancer cell lines
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Correction of Huntington’s Disease Phenotype by Genistein-Induced Autophagy in the Cellular Model
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Sex differences in excess and reservoir arterial blood pressures as markers of phenotype
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Experimental results of full scattering profile from finger tissue-like phantom
PublicationHuman tissue is one of the most complex optical media since it is turbid and nonhomogeneous. We suggest a new optical method for sensing physiological tissue state, based on the collection of the ejected light at all exit angles, to receive the full scattering profile. We built a unique set-up for noninvasive encircled measurement. We use a laser, a photodetector and finger tissues-mimicking phantoms presenting different optical...
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Stożkowe łożyska magnetyczne.
PublicationW artykule przedstawiono konstrukcję stożkowych łożysk magnetycznych. Ten typ łożyska znakomicie nadaje się do łożyskowania krótkich wirników o znacznych średnicach. Autorzy zastosowali łożyska magnetyczne do łożyskowania wirnika pędnika wodnego. W grupie łożysk magnetycznych, podobnie jak w klasycznych łożyskach, można wyróżnić łożyska: promieniowe, osiowe i stożkowe. Przedstawiona klasyfikacja związana jest z kierunkiem przenoszonych...
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Microcapsules and their applications in pharmaceutical and food industry.
PublicationMicroencapsulation is a process in which tiny particles or droplets are surrounded by a coating or embedded in a homogeneous or heterogeneous matrix, to generate small capsules in size range from a few to few thousand micrometers. The material inside the microcapsule is referred to as the core, internal phase, or fill, whereas the wall is sometimes called shell, coating, wall material, or membrane. It has found application in...