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Search results for: 2d and 3d culture models
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Comparison of 2D and 3D culture models in the studies of the biological response induced by unsymmetrical bisacridines in cancer cells
PublicationMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), responsible for cancer progression, metastasis, and recurrence. Therefore, following the initial evaluation of the impact of antitumor unsymmetrical bisacridines (UAs) on lung and colon cancer cells using traditional monolayer cultures, I extended my investigations and applied the spherical model....
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Flow models 1D, 2D, 3D for diagonal pump
PublicationTrzy typowe modele stosowane w maszynach wirnikowych 1D, 2D, 3D zostały przedstawione w zastosowaniu do przepływu w pompie diagonalnej. W ramach modelu 1D przedstawiono prezentację procesu na wykresie energia -straty. W ramach modelu 2D pokazano wynik rozwiązania zadania odwrotnego prowadzącego do kształtu łopatek wirnika pompy. W ramach modelu 3D wykonano obliczenia programem FLUENT pokazując charakterystyczne cechy dwóch różnie...
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Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions
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Naturally-derived hydrogels for 3D pancreatic tumor models: A short review
PublicationStatistics suggest a high proportion of mortality rate by pancreatic cancer, which is a solid tumor characterized by high heterogeneity and the presence of a complex extracellular matrix. The very low effectiveness of pancreatic cancer treatment roots in the high metastatic potential and drug resistance of this tumor. Therefore, the quest for efficient cellular models enabling precise mimicking in vivo conditions, and anticancer...
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The Influence of Antitumor Unsymmetrical Bisacridines on 3D Cancer Spheroids Growth and Viability
PublicationThe culture of 3D spheroids is a promising tool in drug development and testing. Recently, we synthesized a new group of compounds, unsymmetrical bisacridines (UAs), which exhibit high cytotoxicity against various human cell lines and antitumor potency against several xenografts. Here, we describe the ability of four UAs—C-2028, C-2041, C-2045, and C-2053—to influence the growth of HCT116 and H460 spheres and the viability of HCT116...
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CAD Introduction (2023/24)
e-Learning CoursesThe course aim is to demonstrate the application of Computer Aided Design in preparation of architectural drawings and project presentations. No previous CAD experience is necessary. Using hands-on exercises, students explore how to create project presentations using 2D drawings and 3D models created in AutoDesk AutoCAD and other programs.
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CAD. Introduction (2024/25)
e-Learning CoursesThis course introduces students to the application of Computer-Aided Design (CAD) in creating architectural drawings and project presentations. No prior CAD experience is required. Through hands-on exercises, students will learn to create engaging project presentations using 2D drawings and 3D models created in AutoDesk AutoCAD and other industry-standard software.
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CAD. Introduction (2022/2023)
e-Learning CoursesConducting unit: Faculty of ArchitectureField of the study: ArchitectureAcademic year: 2022/2023 Winter TermDuration: 15 weeks (30 hours laboratory per term) Subject objectives: The course aim is to demonstrate the application of Computer Aided Design in preparation of architectural drawings and project presentations. No previous CAD experience is necessary. Using hands-on exercises, students explore how to create project presentations...
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A facile approach to fabricate load-bearing porous polymer scaffolds for bone tissue engineering
PublicationBiodegradable porous scaffolds with oriented interconnected pores and high mechanical are load-bearing biomaterials for bone tissue engineering. Herein, we report a simple, non-toxic, and cost-effective method to fabricate high-strength porous biodegradable scaffolds, composed of a polymer matrix of polycaprolactone (PCL) and water-soluble poly (ethylene oxide) (PEO) as a sacrificial material by integrating annealing treatment,...
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TIME- AND FREQUENCY-DOMAIN QUASI-2D SMALL-SIGNAL MOSFET MODELS
PublicationA novel approach to small-signal MOSFET modeling is presented in this book. As a result, time- and frequency-domain physics-based quasi-2D NQS four-terminal small-signal MOSFET models are proposed. The time-domain model provides the background to a novel DIBL-included quasi‑2D NQS four-terminal frequency-domain small-signal MOSFET model. Parameters and electrical quantities of the frequency-domain model are described by explicit...
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CAD. Integrated Architectural Design, MSc Arch (2023/24)
e-Learning CoursesDetailed understanding of optimizing the design process using parametric BIM (Building Information Modeling) in the Autodesk Revit Architecture program. Practical design exercises included familiarize students with methods of integrating parametric design and exchanging data with other CAD/BIM programs, modifying parametric objects and generating automatic 2D/3D architectural documentation. The lesson plan introduces students to...
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Analiza porównawcza 2D i 3D klasycznego i bezstykowego elektrycznego ogrzewania rozjazdów kolejowych
PublicationElektryczne ogrzewanie rozjazdów jest istotnym problemem technicznym i ekonomicznym. Z tych względów istnieje potrzeba prowadzenia badań w celu optymalizacji systemu ogrzewania rozjazdów kolejowych. W niniejszym artykule przedstawiono wyniki analizy numerycznej układów ogrzewania rozjazdów kolejowych metodą klasyczną oraz z zastosowaniem grzejników odizolowanych termicznie od stopki szyny. Przeprowadzono analizę 2D i 3D rozpatrywanych...
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Trawl-Door Shape Optimization with 3D CFD Models and Local Surrogates
PublicationDesign and optimization of trawl-doors are key factors in minimizing the fuel consumption of fishing vessels. This paper discusses optimization of the trawl-door shapes using high-fidelity 3D computational fluid dynamic (CFD) models. The accurate 3D CFD models are computationally expensive and, therefore, the direct use of traditional optimization algorithms, which often require a large number of evaluations, may be prohibitive....
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Recent advances in 3D bioprinted tumor models for personalized medicine
PublicationCancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a challenging task. Current models suffer from inadequate translation between in vitro and in vivo results, primarily due to the isotropic nature of tumors and their microenvironment's relationship. To address these limitations, hydrogel-based 3D bioprinting...
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3D Morphable Models Application for Expanding Face Database Limited to Single Frontal Face Per Person
Publication1. Zaprezentowany materiał dotyczył badań nad rozszerzeniem dysponowanej bazy wzorców wizerunków twarzy, o dodatkowe wzorce z wariacją w ustawieniu. Dodatkowe wzorce były usyskiwane poprzez przejście z wizerunku twarzy 2D na model 3D, zasymulowanie zadanego ustawienia i powrót do dziedziny 2D (poprzez rzutowanie 3D->2D). W fazie konstrukcji modelu 3D, z wizerunku 2D była ściągana zarówno tekstura twarzy jak i siatka punktów charakterystycznych....
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The effect of numerical 2D and 3D FEM element modelling on strain and stress distributions at laser weld notches in steel sandwich type panels
PublicationLike other means of transport, merchant ships face the problem of increasing requirements concerning the environment protection, which, among other issues, implies the reduction of fuel consumption by the ship. Here, the conventional approach which consists in making use of higher strength steels to decrease the mass of the ship hull can be complemented by the use of new steel structures of sandwich panel type. However, the lack...
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Representative volume element in 2D for disks and in 3D for balls
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Improving the Accuracy of Automatic Reconstruction of 3D Complex Buildings Models from Airborne Lidar Point Clouds
PublicationDue to high requirements of variety of 3D spatial data applications with respect to data amount and quality, automatized, effcient and reliable data acquisition and preprocessing methods are needed. The use of photogrammetry techniques—as well as the light detection and ranging (LiDAR) automatic scanners—are among attractive solutions. However, measurement data are in the form of unorganized point clouds, usually requiring transformation...
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A new method of presosns identification based on comparative analysis of 3D face models
PublicationThe article presents the use of modern close range photogrammetry for possessing highly accurate 3D models of the human face (including the ears). Modern methods used to obtain precise data describing the construction of a human face, and even the whole human body, should allow to get finished measurement material in a very short time. Those features belong to the optical scanning technology. Comparative analysis of models of the...
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Quantification of Asphalt Mixture Interlocking Utilizing 2D and 3D Image Processing
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Porównanie tradycyjnych i komputerowych metod animacji 2D i 3D.
PublicationArtykuł opisuje najważniejsze zagadnienia związane z animacją tworzoną zarówno w sposób tradycyjny, jak i z zastosowaniem technik komputerowych oraz związki między tymi sposobami generowania ruchu.
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Biomechanical properties of 3D-printed bone models
PublicationBone lesions resulting from large traumas or cancer resections can be successfully treated by directly using synthetic materials or in combination with tissue engineering methods (hybrid). Synthetic or hybrid materials combined with bone tissue’s natural ability for regeneration and biological adaptation to the directions of loading, allow for full recovery of its biological functions. Increasing interest in new production methods...
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A Cost-Effective Method for Reconstructing City-Building 3D Models from Sparse Lidar Point Clouds
PublicationThe recent popularization of airborne lidar scanners has provided a steady source of point cloud datasets containing the altitudes of bare earth surface and vegetation features as well as man-made structures. In contrast to terrestrial lidar, which produces dense point clouds of small areas, airborne laser sensors usually deliver sparse datasets that cover large municipalities. The latter are very useful in constructing digital...
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Marek Czachor prof. dr hab.
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Reguły animacji tradycyjnej w komputerowych systemach animacji 2D i 3D
PublicationWykorzystywane obecnie reguły animacji sformułowane zostały ponad 70 lat temu. Artykuł zawiera ich opis i klasyfikację oraz sposoby zastosowania w technice komputerowej. Zaproponowano zestaw testów subiektywnych dotyczących oceny realizmu animacji stworzonych z wykorzystaniem reguł.
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Assessment of the effect of vegetation on the transition of the flood wave using hydraulic 2D models
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Comparative study of high‑pressure fluid flow in densely packed granules using a 3D CFD model in a continuous medium and a simplified 2D DEM‑CFD approach. Granular Matter
PublicationIzotermiczny ściśliwy jednofazowy przepływ cieczy przez niejednorodną masę ziarnistą składającą się z gęsto upakowanych zachodzących na siebie kul imitujących skałę pod wysokim ciśnieniem zbadano numerycznie przy użyciu dwóch różnych podejść. Pierwsze podejście zwane pełnym modelem 3D CFD stosowało metodę skończonych objętości (FVM) do rozwiązania uśrednionego równania Naviera-Stokesa zakładając model naprężeń Reynoldsa (BSL) w...
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Portable parallel simulator using MPI for 2D and 3D domains: design and performance testing
PublicationW artykule prezentujemy szczegóły projektowo-implementacyjne naszego modularnego kodu symulacyjnego z wykorzystaniem MPI, w tym nakładaniem obliczeń i komunikacji. Podkreślamy modularność naszej implementacji pozwalającą na łatwą adaptację kodu dla innych zasotosowań. Prezentujemy związek pomiędzy przyspieszeniem obliczeń, rozmiarem i kształtami trójwymiarowych domen z różnymi stosunkami liczby węzłów aktualizowanych przez procesor...
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Effect of steel fibres on concrete behavior in 2D and 3D simulations using lattice model.
PublicationW artykule przedstawiono wyniki numerycznej symulacji betonu zbrojonego włóknami stalowymi. Beton został opisany w skali mezo jako materiał 3-fazowy przy zastosowaniu modelu sieciowego. Obliczenia wykonano dla rozciągania jednoosiowego. Porównano ze sobą wyniki dwu- i trójwymiarowe.
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Electrochemical performance of MOF-5 derived carbon nanocomposites with 1D, 2D and 3D carbon structures
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Organizational culture and coopetition: An exploratory study of the features, models and role in the Polish Aviation Industry
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Przegląd programów 2D oraz 3D do fotogrametrii na przykładzie PC- Rect oraz PhotoModeler
PublicationW pracy został podjęty temat przeglądu programów do fotogrametrii. Stwierdzono, że lawinowy rozwój informatyki sprawił, że eksperci zajmujący się zawodowo tematem zdarzeń drogowych pozyskali dostęp do specjalistycznego oprogramowania wspomagającego rekonstrukcję wypadków komunikacyjnych. Różnorodność problematyki rekonstruowania zdarzeń drogowych narzuciła konieczność stworzenia eksperckiego oprogramowania specjalnej grupy aplikacji....
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267: Mesenchymal cells regulate growth of intestinal crypts by a Wnt independent mechanism in 3D culture system
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Results and models for Novel high frequency components with non-conventional shape employing smooth geometry deformation of 3D solid with FFD
Open Research DataThe project aims to investigate the possibility of developing and manufacturing novel high frequency devices having non-standard geometries, allowing for improved electromagnetic performance over what is achievable with currently available design tools. The non-conventional geometry will be obtained by employing the free-form shape deformation technique...
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3D Model Preparing Patterns for Interactive Urban Visualization - Guidelines for Graphic Designers Preparing 3D Models for Virtual Reality Applications
PublicationWhile working on architectural visualizations, the software developer often has to work with graphic designers who create models in a different environment what can cause many complications. For this reason, it is very important to have some guidelines which can protect both the developer and the designer from commixing mistakes. The paper presents a list of such guidelines based on the authors’ experience. The reader can treat...
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GIS Technology, 3D Models and Mathematical Models as a Tool for Assessing Development Capabilities of Flood Risk Land to Make Arrangements of Municipal Planning Documents
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Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models
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Case Study NEB Atlas / part I - 3D Models / Brunnshög, Lund
Open Research DataThe data presents the results of work on the analysis of contemporary neighbourhoods. The aim of this part of the research was to create a digital model - a simplified digital twin - for selected parts of housing estates already realised in various cities in Europe. This group presents a model for a fragment of the Brunnshög district in Lund, Sweden....
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Simulations of high-pressure fluid flow in a pre-cracked rock specimen composed of densely packed bonded spheres using a 3D CFD model and simplified 2D coupled CFD-DEM approach
PublicationW artykule zastosowano dwa różne podejścia do opisu jednofazowego przepływu płynu w wstępnie spękanej próbce skały o niskiej porowatości pod wysokim ciśnieniem. Głównym celem pracy było bezpośrednie porównanie rozkładu ciśnień, gęstości i prędkości płynów we wstępnie pękniętej próbce. Zachowanie próbki imitującej skałę zostało opisane przez gęsto upakowane połączone kohezją kulki z nakładającymi się na siebie elementami. Pierwsze...
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Case Study NEB Atlas / part I - 3D Models / King's Cross, London
Open Research DataThe data presents the results of work on the analysis of contemporary neighbourhoods. The aim of this part of the research was to create a digital model - a simplified digital twin - for selected parts of housing estates already realised in various cities in Europe. This group presents a model for a fragment of the King's Cross, London, UK. The students...
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Wiktoria Wojnicz dr hab. inż.
PeopleDSc in Mechanics (in the field of Biomechanics) - Lodz Univeristy of Technology, 2019 PhD in Mechanics (in the field of Biomechanics) - Lodz Univeristy of Technology, 2009 (with distinction) List of papers (2009 - ) Wojnicz W., Wittbrodt E., Analysis of muscles' behaviour. Part I. The computational model of muscle. Acta of Bioengineering and Biomechanics, Vol. 11, No.4, 2009, p. 15-21 Wojnicz W., Wittbrodt E., Analysis of...
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Reconstruction of 3D structure of positive corona streamer by local methods
PublicationThe computer algorithms were used for reconstruction of streamer 3D structure. We propose the 3D tree structure model of corona discharge streamer composed with nodes and edges between chosen couples of nodes, which enables easy computation of some important parameters ofstreamers. The 3D model can be derived directly from two projection images by global methods like evolutionary searching or particle simulations. In this paper...
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Nonlinear resultant theory of shells accounting for thermodiffusion
PublicationThe complete nonlinear resultant 2D model of shell thermodiffusion is developed. All 2D balance laws and the entropy imbalance are formulated by direct through-the-thickness integration of respective 3D laws of continuum thermodiffusion. This leads to a more rich thermodynamic structure of our 2D model with several additional 2D fields not present in the 3D parent model. Constitutive equations of elastic thermodiffusive shells...
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Computer vision techniques applied for reconstruction of seafloor 3D images from side scan and synthetic aperture sonars data
PublicationThe Side Scan Sonar and Synthetic Aperture Sonar are well known echo signal processing technologies that produce 2D images of the seafloor. Both systems combines a number of acoustic pings to form a high resolution image of seafloor. It was shown in numerous papers that 2D images acquired by such systems can be transformed into 3D models of seafloor surface by algorithmic approach using intensity information, contained in a grayscaled...
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A method for the three-dimensional and synchronous resolution of functional and spatial matters in architectural design
PublicationThe article discusses the issue of applied methods of teaching architectural design at Polish universities. The authors review the common methods based on conceptual drawings solving design problems in only two dimensions. After completing the floor plans' sketching process carried out in 2D way the 3D virtual models are made - seldom cardboard mock-ups - to illustrate the final spatial form of the designed object. At the Faculty...
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On the correspondence between two- and three-dimensional Eshelby tensors
PublicationWe consider both three-dimensional (3D) and two-dimensional (2D) Eshelby tensors known also as energy–momentum tensors or chemical potential tensors, which are introduced within the nonlinear elasticity and the resultant nonlinear shell theory, respectively. We demonstrate that 2D Eshelby tensor is introduced earlier directly using 2D constitutive equations of nonlinear shells and can be derived also using the throughthe-thickness...
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Cellular Effects of Selected Unsymmetrical Bisacridines on the Multicellular Tumor Spheroids of HCT116 Colon and A549 Lung Cancer Cells in Comparison to Monolayer Cultures
PublicationMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), which are responsible for cancer progression, metastasis, and recurrence. Therefore, we applied this model in our studies of highly active antitumor unsymmetrical bisacridines (UAs). We investigated the cellular response induced by UAs in 2D and 3D cultures of HCT116 colon and A549 lung cancer...
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Theory of Elasticity and Plasticity - Civil Engineering, sem. I
e-Learning CoursesPreliminaries in Solid Body Mechanics focused on 2D and 3D engineering structures, in analytical approach
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Autonomous pick-and-place system based on multiple 3Dsensors and deep learning
PublicationGrasping objects and manipulating them is the main way the robot interacts with its environment. However, for robots to operate in a dynamic environment, a system for determining the gripping position for objects in the scene is also required. For this purpose, neural networks segmenting the point cloud are usually applied. However, training such networks is very complex and their results are unsatisfactory. Therefore, we propose...
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Autonomous Perception and Grasp Generation Based on Multiple 3D Sensors and Deep Learning
PublicationGrasping objects and manipulating them is the main way the robot interacts with its environment. However, for robots to operate in a dynamic environment, a system for determining the gripping position for objects in the scene is also required. For this purpose, neural networks segmenting the point cloud are usually applied. However, training such networks is very complex and their results are unsatisfactory. Therefore, we propose...