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Search results for: LINEAR HYPERTREE
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Generalization of Phylogenetic Matching Metrics with Experimental Tests of Practical Advantages
PublicationThe ability to quantify a dissimilarity of different phylogenetic trees is required in various types of phylogenetic studies, for example, such metrics are used to assess the quality of phylogeny construction methods and to define optimization criteria in supertree building algorithms. In this article, starting from the already described concept of matching metrics, we define three new metrics for rooted phylogenetic trees. One...
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Electrochemical simulation of enzymatic transformations studied for the selected antitumor acridine derivatives
PublicationThe elucidation of the metabolic pathways and the biotransformation mechanisms of potential drugs is a crucial point in drug development. It allows to know the activation routes of the new biologically active compounds, especially in respect to their possible toxicity. Generally, in vivo or in vitro experiments with liver microsomes or hepatocytes are performed. However, these testing schemes are tedious, time consuming and of...
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Electrochemistry meets enzymes: Investigation of the biotransformation pathway of C-1311 based on electrochemical simulation in comparison to in vitro methods.
PublicationThe knowledge of the metabolic pathways and the biotransformation of new drugs is one of the major challenges in pharmaceutical research. It is crucial for elucidation of degradation routes of the new biologically active compounds, especially in the area of possible toxicity. Conventional in vitro drug metabolism studies are based on incubating drug candidate with e.g. hepatocytes or, most importantly, liver cell microsomes and...
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Analysis of sloping brace stiffness influence on stability and load bearing capacity of a truss
PublicationThe paper is focused on the numerical study of stability and load bearing capacity of a truss with side elastic braces. The structure is made in reality. The rotational and sliding brace stiffnesses were taken into account. Linear buckling analysis and non-linear static analysis with geometric and material nonlinearity were performed for the beam and shell model of the truss with respect to the angle of sloping braces. As a result...
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Distance measurement errors in silent FM-CW sonar with matched filtering
PublicationThe secretiveness of sonar operation can be achieved by using continuous frequency-modulated sounding signalswith reduced power and significantly prolonged repeat time. The application of matched filtration in the sonarreceiver provides optimal conditions for detection against the background of white noise and reverberation, and avery good resolution of distance measurements of motionless targets. The article shows that target...
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Polypyrrole based gas sensor for ammonia detection
PublicationThe nature of polypyrrole response to toxic gases does not allow using the sensor in a conventional way. The main aim of this study is to acquire the information about the concentration using different approaches: a linear approximation, a non-linear approximation and a tangent method. In this paper a two-steps procedure for sensor response measurements has been utilized. Polypyrrole films were electrochemically synthesized on...
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Stability of an imperfect truss loaded by wind
PublicationThe present paper is devoted to the numerical research of stability of a truss loaded by wind and stiffened by elastic supports located at the top chord. The lateral braces or lateral and torsional braces were taken into account. In this paper, the linear buckling analysis re- sults for the beam and shell model were presented. Two different shapes of initial geometric imperfections were considered in the non-linear static analysis...
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Silver complexes stabilized by large silanethiolate ligands – crystal structures and luminescence properties
PublicationBulky silanethiolate and disiladithiolate ligands were applied to synthesize one mononuclear and three trinuclear silver complexes including two cyclic “microclusters” and a linear tri-nuclear silanethiolate complex. All obtained compounds are characterized by X-ray diffraction and FT-IR. NMR and emission spectroscopies were used where possible. The first trinuclear anionic silver thiolate is structurally characterized. The influence...
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Fundamentals of classical and analytical mechanics
PublicationThe book is a monographic description of the present attempt to Newtonian and Lagrangian mechanics. But also, it could be found as a supplementary educational material useful for the graduate courses in mechanics taken by students majoring in mechanical engineering, physics or physical science. In the book you can find a brief introduction to concepts and principles of algebra of vectors; Kinematics of particles, mainly focused...
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US not bright but right method of thyroid volume estimation even in large and substernal extended goitres. Comparison of US and three methods of CT thyroid evaluation - prospective study.ON LINE
PublicationBackground Ultrasound is nowadays a method of choice for thyroid volume assessment. However, its disadvantage is some inaccuracy, which is said to be higher in huge, especially substernally extended goitres. Aims The aim of the study was to compare the US and CT thyroid volumetric measurements: multi-observers (CT MO) and one-observer (CT OO) to CT planimetry results (CT Pl) in patients with large goitres. Materials & Methods The...
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In silico modelling for predicting the cationic hydrophobicity and cytotoxicity of ionic liquids towards the Leukemia rat cell line, Vibrio fischeri and Scenedesmus vacuolatus based on molecular interaction potentials of ions
PublicationIn this study we present prediction models for estimating in silico the cationic hydrophobicity and the cytotoxicity (log [1/EC50]) of ionic liquids (ILs) towards the Leukemia rat cell line (IPC-81), the marine bacterium Vibrio fischeri and the limnic green algae Scenedesmus vacuolatus using linear free energy relationship (LFER) descriptors computed by COSMO calculations. The LFER descriptors used for the prediction model (i.e....
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Comparative analysis of mRNA transcripts of HT-29 cell line expressed in identical quantities for pathogenic E. coli strains UM146 and UM147 with control Escherichia coli Nissle 1917
PublicationAim of study was comparative analysis of mRNA transcripts of HT-29 cell line, expressed in identical quantities for the combination of pathogenic and non-pathogenic Escherichia coli strains. HT-29 confluent monolayers infection with two pathogenic E. coli strains UM146 and UM147 resulted in two sets of mRNA transcripts that were identical with RNA transcripts obtained for non-pathogenic one strain E. coli Nissle 1917. In this study...
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A study of electron impact excitation of molecular oxygen at a scattering angle of 180 st.
PublicationZbadano wzbudzenie tlenu cząsteczkowego w zderzeniu z elektronem dla rozproszenia do tyłu, pod kątem 180 st. Do pomiarów wykorzystano nowe źródło lokalnego pola magnetycznego o geometrii stożkowej.
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Measurements of differential cross sections for elastic electron scattering in the backward direction by molecular oxygen.
PublicationZmierzono różniczkowe przekroje czynne na rozproszenie sprężyste elektronów na cząsteczkach tlenu w zakresie kątów rozproszenia 100-180 st., dla wybranych energii padających elektronów w przedziale 7-20eV. Do pomiarów wykorzystano metodę lokalnego pola magnetycznego.
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Features of load and wear of main propulsion devices on sea-going ships with piston combustion engines and their impact on changes in technical states of the systems
PublicationThe paper presents the specificity of operation of propulsion systems of seagoing ships which causes the need to control the load on them, especially on their engines called main engines. The characteristics of the load on the propulsion systems, especially on the main engines as well as on the shaft lines and propellers driven by the engines, along with the process of wear in tribological joints (sliding tribological systems)...
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ANALYSIS OF BRACE STIFFNESS INFLUENCE ON STABILITY OF THE TRUSS
PublicationThe paper is devoted to the numerical and experimental research of stability of a truss with side elastic supports at the top chord. The structure is a model of a real roof truss scaled by factor ¼. The linear buckling analysis and non-linear static analysis were carried out. The buckling length factor for the compressed top chord was calculated and the limit load for the imperfect truss shell model with respect to brace stiffness...
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Application of the Boundary Element Method for the Simulation of Two-dimensional Viscous Incompressible Flow
PublicationThe paper presents the application of an indirect variant of the boundary element method (BEM) to solve the two-dimensional steady flow of a Stokes liquid. In the BEM, a system of differential equations is transformed into integral equations. Thi smakes it possible to limit discretization to the border of the solution. Numerical discretization of the computational domain was performed with linear boundary elements, for which a...
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A selection of PID type controller settings via LQR approach for two-wheeled balancing robot
PublicationThe problem of PID type controller tuning has been addressed in this paper. In particular, a method of selection of PD settings based on the solution of linear–quadratic optimisation problem using the energy criterion has been investigated. Thus, the possibility of transforming optimal settings of the linear–quadratic regulator into the settings of the controller in the classical control system has been given. The presented methodology...
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METHOD FOR SHIP'S ROLLING PERIOD PREDICTION WITH REGARD TO NON-LINEARITY OF GZ CURVE
PublicationThe paper deals with the problem of prediction of the rolling period. A special emphasis is put on the practical application of the new method for rolling period prediction with regard to non-linearity of the GZ curve. The one degree-of-freedom rolling equation is applied with using the non-linear stiffness moment and linear damping moment formulas. A number of ships are considered to research the discrepancies between the pending...
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The analysis of the determination of points positions using photogrammetric methods
PublicationThis article was created as a result of research conducted within the master thesis. The purpose of the research was to analyze the accuracy of determining the actual position of the photographed points according to the calculated parameters. The accuracy of photos alignment was determined as parameters, which determine their external and internal orientation. In order to determine the location of the determined points, it was...
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ANALIZA PRZEPUSTOWOŚCI WYBRANEGO UKŁADU TOROWEGO W PRZESTRZENI CZĘŚCIOWO – UPORZĄDKOWANEJ
PublicationNa sieci kolejowej istotny wpływ na płynność ruchu mają odpowiednio usytuowane odcinki odstępowe. Z podobną sytuacją mamy do czynienia przy modernizacji stacji kolejowych i tworzeniu nowych rozwiązań, w których należy uwzględnić prognozy rozwoju ruchu na danym elemencie sieci kolejowej. Jednak w przypadku stacji sytuacja staje się dużo bardziej skomplikowana i kosztowna, gdyż poprawa przepustowości wymaga istotnych zmian organizacyjnych...
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Structural properties of hydration shell around various conformations of simple polypeptides
PublicationIn this paper we investigate structural properties of water within the solvation shell around the peptide core created by a well-defined conformation of polypeptide chain. The following secondary structures are investigated: linear (straight chain), and three helices PII (polyproline-like), 310, and α. We propose using the two-particle contribution to entropy as a rational measure of the water structural ordering within the solvation...
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New generation of the satellite hydraulic pumps
PublicationHydraulic satellite machines are known and produced in many versions, recognizable by the number of humps on their inner rotor and external gear, and therefore by the number of cooperating gears (satellites). All known shapes were however designed on the base of preliminary assumption that rotor’s and external gear’s pitch lines are formed by merging arcs, tangent to each other in the. This assumption makes calculations easier,...
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Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n–6) to α-Linolenic Acid (ALA, C18:3n–3) Ratio on the Mouse Liver Proteome
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Inverse Flood Routing Using Simplified Flow Equations
PublicationThe paper considers the problem of inverse flood routing in reservoir operation strategy. The aim of the work is to investigate the possibility of determining the hydrograph at the upstream end based on the hydrograph required at the downstream end using simplified open channel flow models. To accomplish this, the linear kinematic wave equation, the diffusive wave equation and the linear Muskingum equation are considered. To achieve...
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Style liderów. Analiza na podstawie wybranych przykładów z polityki, kultury oraz indywidualnych wywiadów pogłębionych
PublicationStyle liderów. Analiza na podstawie przykładów z polityki, kultury oraz indywidualnych wywiadów pogłębionych " Angelica Pegani Tematem niniejszej pracy stały się style liderów, ich analiza na podstawie wybranych przykładów z polityki, kultury oraz badań własnych. Celem pracy jest udzielenie odpowiedzi na pytania: jakie są cechy charakterystyczne lidera? Które style liderów występują w świecie polityki i kultury? Czy kobieta...
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Stability of a truss under upward wind loading
PublicationThe present paper is devoted to the numerical investigations of stability of a truss under upward wind load. The truss is braced at its the upper cord. A structural variant including lateral braces, or lateral and torsional braces is considered. The research presents the problems of linear buckling and non-linear static analysis of the truss shell and beam model with geometric and material non-linearity are presented. The initial...
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Biomass estimation using a length-weight relationship in beetle larvae (Coleoptera: Aphodiidae, Histeridae, Hydrophilidae, Staphylinidae) obtained from cow dung
PublicationThis research enabled the relationship between length and dry body mass to be determined for 158 beetle larvaetaken from cow dung in north-eastern Poland. The larvae were divided into three morphological types, for which the power and linear function of the body length-weight relationship were determined. The linear regression equation characterizes the relationship between body weight and...
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M-integral for finite anti-plane shear of a nonlinear elastic matrix with rigid inclusions
PublicationThe path-independent M-integral plays an important role in analysis of solids with inhomogeneities. However, the available applications are almost limited to linear-elastic or physically non-linear power law type materials under the assumption of infinitesimal strains. In this paper we formulate the M-integral for a class of hyperelastic solids undergoing finite anti-plane shear deformation. As an application we consider the problem...
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Correction: Bocheńska, K. et al. Lysosome Alterations in the Human Epithelial Cell Line HaCaT and Skin Specimens: Relevance to Psoriasis. Int. J. Mol. Sci. 2019, 20, 2255
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Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoli- ne-3,7-done derivatives a novel group of anticancer agents active on a multidrug resistance cell line.
PublicationZsyntezowano serię pochodnych pirydazonu z jednym lub dwoma łańcuchami bocznymi w różnych pozycjach chromoforu tetracyklicznego. Związki wykazały aktywność cytoksyczną na mysią białaczkę L1210 i ludzką k562 oraz na linii komórkowej oporności krzyżowej MDR (k562/DX). Dwa najbardziej aktywne związki przetestowano in vivo na mysiej białaczce P388. Wykazały one aktywność przeciwnowotworową porównywalną z aktywnością Mitoxantronu.
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Panax quinquefolium L. Ginsenosides from Hairy Root Cultures and Their Clones Exert Cytotoxic, Genotoxic and Pro-Apoptotic Activity towards Human Colon Adenocarcinoma Cell Line Caco-2
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New conjugates of mycophenolic acid and their antiproliferative activity
PublicationThe new conjugates of mycophenolic acid (MPA) were obtained in the reaction of N6-(ω-aminoalkyl)adenosines with MPA in the presence of EDCI as a coupling reagent. New compounds 4a–h were evaluated on leukemia cell line (Jurkat) and PBMC from healthy donors. Length of the linker influenced observed activity. The compound 4b possessing 1,3-diamine spacer exhibited the most promising results and can be considered to further investigations.
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Flexural buckling and post-buckling of columns made of aluminium alloy
PublicationThe paper concerns flexural buckling and initial post-buckling of axially compressed columns made of aluminium alloy described by the Ramberg-Osgood relationship. The non-linear differential equation of the problem is derived using the stationary total energy principle and the assumptions of classical beam theory within a finite range. The approximate analytical solution of the equation leading to the buckling loads and initial...
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Buckling and initial post-local buckling behaviour of cold-formed channel member flange
PublicationThe initial post-buckling behaviour of a cold-formed channel member flange after its local buckling is investigated. An axially compressed column or beam subjected to pure bending is considered. The member material is assumed to follow a linear stress-strain relationship. The governing non-linear differential equation of the problem is derived using the minimum total potential energy principle. An approximate solution for the equation...
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A simplified approach to determine the expiration date of certified reference material based on the results of monitoring long-term stability
PublicationAll components of the quality assurance (QA) system for measurement results depend heavily on certified reference materials (CRMs). There is a need for a comprehensive discussion of the stability study using the CRM statistical method. Monitoring involves periodic sampling and analysis of the CRM at predetermined intervals to continuously monitor stability without compromising its integrity. The obtained stability data is then...
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Artificial Thermal Ageing of Polyester Reinforced and Polyvinyl Chloride Coated Technical Fabric
PublicationArchitectural fabric AF9032 has been subjected to artificial thermal ageing to determine changes of the material parameters of the fabric. The proposed method is based on the accelerated ageing approach proposed by Arrhenius. 300 mm x 50 mm samples were cut in the warp and fill directions and placed in a thermal chamber at 80 °C for up to 12 weeks or at 90 °C for up to 6 weeks. Then after one week of conditioning at ambient temperature,...
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Method of determining the residual fluxes in transformer core
PublicationThe article presents the method of calculating the residual induction in transformer columns. The method is based on measurement of the magnetic induction in selected points around the transformer core. The values of residual induction are calculated as linear combination of the results of measurement.
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Analysis of latency between quotations and capital flow in capital markets.
PublicationThe aim of this paper is to prove that the derivative of the log of capital flow understood as price times volume advances the derivative of log of the price. A certain concept of signal processing using linear filtering has been proposed to conduct the research.
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STABILITY ANALYSIS OF A TRUSS WITH SLOPING ELASTIC BRACES
PublicationSteel trusses have a much greater strength and stiffness in their plane than out of their plane, and therefore should be braced against lateral deflection and twisting. Such elements like purlins apart from bearing vertical load are part of bracing that stabilize roof trusses against distortional buckling. The stability of trusses with elastic bracing was investigated in an experimental research. Braces situated at some angle measured...
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Crystal Growth, Structure, and Magnetism of the 2D Spin 1/2 Triangular Lattice Material Rb3Yb(PO4)2
PublicationThe single-crystal growth, crystal structure, heat capacity, and anisotropic magnetization characterization of Rb3Yb- (PO4)2, a Yb-based triangular lattice material, are presented. Single-crystal X-ray diffraction shows that Rb3Yb(PO4)2 exhibits [Yb(PO4)]∞ layers, with the Yb in an ordered plane of equilateral triangles. One phosphate group oxygen that is not a near neighbor of the magnetic Yb displays positional disorder. The...
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Electron scattering from tin tetrachloride (SnCl4) molecules
PublicationAbsolute grand-total cross section (TCS) for electron scattering from a tin tetrachloride, SnCl4, molecule was measured at electron-impact energies ranging from 0.6 to 300 eV, in the linear electron-transmission experiment. The measured TCS energy dependence shows two very pronounced enhancements peaking near 1.2 eV and around 9.5 eV, separated with a deep minimum centered close to 3 eV. The low energy structure is attributed to...
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Balance error generated by numerical diffusion in the solution of Muskingum equation
PublicationIn the paper the conservative properties of the lumped hydrological models with variable parameters are discussed. It is shown that in the case of the non-linear Muskingum equation the mass balance is not satisfied. The study indicates that the mass balance errors are caused by the improper form of equation and by the numerical diffusion which is generated in the solution. It has been shown that the classical way of derivation...
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Ultrawideband transmission in physical channels: a broadband interference view
PublicationThe superposition of multipath components (MPC) of an emitted wave, formed by reflections from limiting surfaces and obstacles in the propagation area, strongly affects communication signals. In the case of modern wideband systems, the effect should be seen as a broadband counterpart of classical interference which is the cause of fading in narrowband systems. This paper shows that in wideband communications, the time- and frequency-domain...
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Dynamic Analysis of the Turnout Diverging Track for HSR with Variable Curvature Sections
PublicationThe paper presents an analytical method of identifying the curvature of the turnout diverging track consisting of sections of varying curvature. Both linear and nonlinear (polynomial) curvatures of the turnout diverging track are identified and evaluated in the paper. The presented method is a universal one, it enables to assume curvature values at the beginning and end point of the geometrical layout of the turnout. The results...
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Analysis of 2D Feature Spaces for Deep Learning-based Speech Recognition
Publicationconvolutional neural network (CNN) which is a class of deep, feed-forward artificial neural network. We decided to analyze audio signal feature maps, namely spectrograms, linear and Mel-scale cepstrograms, and chromagrams. The choice was made upon the fact that CNN performs well in 2D data-oriented processing contexts. Feature maps were employed in the Lithuanian word recognition task. The spectral analysis led to the highest word...
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Gas sensors based on conducting polymers-recent developments
PublicationThis work discusses sensing performance dependence of PEDOT polymer and its composites on the counter ions used in the polymerization process. The sensors based on PEDOT-RGO composite show reversible response to NO2, while on PEDOT/LiClO4 irreversible. As a result, PEDOT-RGO could be used as a typical gas sensor, while sensor based PEDOT/LiClO4 could be used as an integrating gas sensor, also known as an accumulating gas sensor....
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Modeling variable curvature on the turnout diverging track length
PublicationThe paper presents three variants of variable curvature application on the entire length of the turnout diverging track. One linear and two nonlinear curvature cases: described the function of C1 and C0 class were considered. It turned out that both linear curve and the function of C1 class requires a significant (even twice) length of diverging track extending with respect to the base turnout. The curvature described by the function...
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Cross sections for ionization and ionic fragmentation of pyrimidine molecules by electron collisions
PublicationThe electron impact mass spectroscopy and the total ion collection measurements were used to investigate the ionization and ionic fragmentation of the pyrimidine, C4H4N2, molecules in the gasphase. The cation mass spectra were measured in the 10−85 amu range and the observed mass peaks assigned to corresponding ionic fragments. The most abundant cation in the mass spectra is the parent cation, C4H4N+2, at 80 amu. The appearance...
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Lekcja z e-doświadczeniem :Obwody prądu stałego
Publicationartykuł ma na celi pokazanie i zachęcenie do głębszego zapoznania się z e-doświadczeniami dot. obwodów prądu stałego