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Search results for: INTERCULTURAL STUDIES
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ADSRRS-fingerprinting and PCR MP techniques for studies of intraspecies genetic relatedness in Staphylococcus aureus
PublicationW pracy pokazano użyteczność dwóch nowych metod do typowania molekularnego Staphylococcus aureus, ADSRRS-fingerprinting (Amplification of DNA fragments Surrounding Rare Restriction Sites) i PCR MP (PCR melting profile). Przebadano 37 szczepów Staphylococcus aureus izolowanych od pacjentów z czyracznością. Jako metodę referencyjną zastosowano REA-PFGE. Okazało się, że izolaty Staphylococcus aureus z nosa od niektórych pacjentów...
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The bioactivity of processed garlic (Allium sativum L.) as shown in vitro and in vivo studies on rats
PublicationCzosnek w trakcie procesu obróbki traci znaczną część swojej bioaktywności. Właściwości przeciwutleniające zmierzone metodą FRAP i DPPH stwierdzono na najwyższym poziomie w przypadku czosnku surowego oraz po krótkim okresie gotowania. Badania na szczurach poddanych diecie z dodatkiem krótkogotowanego czosnku potwierdziły, że proces ten nie zaburza właściwości przeciwutleniających surowego czosnku. U zwierząt stwierdzono poprawę...
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Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: In vitro studies
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Studies on the solid-liquid equilibria and intermolecular interactions Urea binary mixtures with Sulfanilamide and Sulfacetamide
PublicationThe binary phase diagrams of Sulfanilamide-Urea (SN-U) and Sulfacetamide-Urea (SC-U) were measured using differential scanning calorimetry technique (DSC). Both examined mixtures were found to form simple binary eutectics. The limited miscibility in the solid state observed by DSC, proving inability of co-crystallization in new multi-molecular form, was also confirmed using PXRD and FTIR-ATR measurements of solid dispersions...
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Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies
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DNA restriction analysis as a supportive tool in mechanistic studies carried out by 32P-postlabelling
PublicationNumerous antitumor and carcinogenic compounds are able to modify DNA by forming covalent bonds with its constituents, while some anticarcinogenic compounds are known to prevent such a modification. All these processes are of vital biological import_ance, though deeper inside into factors influencing formation of DNA adducts is difficult due to the low level of their occurrence. 32P-Postlabelling approach ensures very sensitive...
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Studies of kicking of three targets – does sex differentiate the velocity of the taekwondo front kick?
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Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples
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Application of Bayesian Multilevel Modeling in the Quantitative Structure–Retention Relationship Studies of Heterogeneous Compounds
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Conformational studies of vasopressin analogues modified with N-methylphenylalanine enantiomers in dimethyl sulfoxide solution
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Conformational Preferences of Proline Derivatives Incorporated into Vasopressin Analogues: NMR and Molecular Modelling Studies
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Experience based knowledge representation for Internet of Things and Cyber Physical Systems with case studies
PublicationCyber Physical Systems and Internet of Things have grown significant attention from industry and academia during the past decade. The main reason behind this interest is the capabilities of such technologies to revolutionize human life since they appear as seamlessly integrating classical networks, networked objects and people to create more efficient environments. However, enhancing these technologies with intelligent skills becomes...
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Interatomic potential suitable for the modeling of penta-graphene: Molecular statics/molecular dynamics studies
PublicationWe test the potentials available for elemental carbon, with the scope to choose the potential suitable for the modeling of penta-graphene, the latest two dimensional carbon allotrope. By using molecular statics and molecular dynamics simulations we show that there is only one potential e namely the Tersoff-type potential proposed by Erhart and Albe in 2005 e which is able to correctly describe all the important features of penta-graphene....
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Application of chemometric techniques in studies of toxicity of selected commercially available products for infants and children
PublicationThe goal of the present study is to assess the impact of the experimental conditions for extraction procedures (time of extraction, thermal treatment and type of extraction media) as applied to several baby and infant products checked for their possible ecotoxicological response when tested by various ecotoxicity tests(Microtox®, Ostracodtoxkit F™and Xenoscreen YES/YAS™). The systems under consideration are multidimensional by...
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Numerical Simulations and Tracer Studies as a Tool to Support Water Circulation Modeling in Breeding Reservoirs
PublicationThe article presents a proposal of a method for computer-aided design and analysis of breeding reservoirs in zoos and aquariums. The method applied involves the use of computer simulations of water circulation in breeding pools. A mathematical model of a pool was developed, and a tracer study was carried out. A simplified model of two-dimensional flow in the form of a biharmonic equation for the stream function (converted into...
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Rigid polyurethane foams modified with ground tire rubber - mechanical, morphological and thermal studies
PublicationRigid polyurethane foams, prepared by a single step method, were modified with the two types of ground tire rubber particles, i.e. untreated and thermo-mechanically reclaimed by using a co-rotating twin screw extruder. The foaming process as well as the structure and the physical, mechanical and thermal properties of the resulting foams were investigated. The presence of ground tire rubber decreased the velocity of polymerization....
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Thermophysical Properties of the Phase Change Material Mixtures – Preliminary Studies on Macromolecular Hydrocarbons Example.
PublicationThe aim of this work is a theoretical and experimental analysis of the macromolecular hydrocarbons mixtures composition and the impact on thermophysical parameters of the phase change materials (PCM) made from these mixtures. The analysis of the current state of knowledge extended by the author's own studies have been presented. Thermophysical characteristics of the hydrocarbons and their mixtures have been specified, in such a...
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Aqueous solutions of NMA, Na2HPO4 , and NaH2PO4 as models for interaction studies in phosphate–protein systems
PublicationPhosphate buffers are essential for many areas of studies. However, their influence on buffered systems is often ignored. The phosphate salts can interact with biologically important macromolecules (e.g. proteins) and stabilize or destabilize them. With our research, we want to answer question what kind of interactions, if any, occur between phosphate ions and a protein backbone model — N-methylacetamide (NMA). ATR-FTIR spectroscopy...
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Effect of osmolytes of different type on DNA behavior in aqueous solution. Experimental and theoretical studies
PublicationOsmolytes, the small organic molecules accumulated in cells under environmental stress, can modulate the stability of biopolymers such as proteins and DNA. In spite of many years of research, there is no established molecular mechanism of the influence of osmolytes on DNA structure. Here, we used two model osmolytes that denature (urea) or stabilize (trimethylglycine, TMG) proteins to study their effect on DNA in aqueous solutions...
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Selected aspects of two-phase flow studies using different visualization techniques in minichannels
PublicationThe subject of the study is to present the possibility of the use of visualization techniques in the researches on two-phase flows, carried out by the authors for many years. These works included as follows: heat transfer during the flow boiling, boiling crises and condensation in flow. The issue of the heat transfer intensification during the flow boiling through the channels of small diameters was analyzed. All this work focused...
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Toxoplasma gondii recombinant antigens as tools for serodiagnosis of human toxoplasmosis: current status of studies
PublicationToxoplasma gondii is a parasitic protozoan which is the cause of toxoplasmosis. Although human toxoplasmosis in healthy adults is usually asymptomatic, serious disease can occur in the case of congenital infections and immunocompromised individuals. Furthermore, despite the exact recognition of its etiology, it still presents a diagnostic problem. Diagnosis of toxoplasmosis is mainly based on the results of serological tests detecting...
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Lobularia libyca: Phytochemical Profiling, Antioxidant and Antimicrobial Activity Using In Vitro and In Silico Studies
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Studies of oil-in-water emulsion stability in the presence of new dicephalic saccharide-derived surfactants
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Plants of the Genus Terminalia: An Insight on Its Biological Potentials, Pre-Clinical and Clinical Studies
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Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease
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Mechanistic studies of the hydrolysis of p-nitrophenyl sulfate catalyzed by arylsulfatase from Helix pomatia
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Naphthyl-vs. anthrylpyridine-2,6-dicarboxamides in cation binding studies. Synthesis and spectroscopic properties
PublicationPyridine-2,6-carboxamides bearing - or -naphthyl- and - or -anthryl- residues were prepared using simple method from pyridine-2,6-carboxylic acid dichloride and the respective aromatic amines. For the obtained receptors selective binding of lead(II), and copper(II) was found. Ion-receptor interactions were studied using UV-vis spectroscopy, spectrofluorimetry, 1H NMR, and FTIR spectroscopy. The reversible lead(II) and copper(II)...
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Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities
PublicationAll activities should aim to eliminate genotoxic impurities and/or protect the API against degradation. There is a necessity to monitor impurities from all classification groups, hence ivabradine forced degradation studies were performed. Ivabradine was proved to be quite durable active substance, but still new and with insufficient stability data. Increased temperature, acid, base, oxidation reagents and light were found to cause...
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Studies on applicability of new solid-phase microextraction and determination of short - chain monocarboxylic acids
PublicationA convenient approach to monitor the short-chain monocaroboksylic acids (SCAMs) in different samples is gas chromatography (GC) preceded by sample preparation based on solid-phase microextraction (SPME). The fiber with polar coatings were used to extract the SCAMs from headspace of liquid and solid samples. Recently polimeric ionic liquid (PIL) fiber coatings have been proposed to extract volatile organic compounds, minly polar...
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Case studies of resonance phenomena in high voltage overhead power lines with shunt reactors
PublicationMisguided design of the towers of power transmission lines can lead to serious problems such as voltage asymmetry, overvoltages, electric arc extinction difficulties or resonance – in case of double circuit line with shunt reactors. The paper points out those threats on example of 400 kV double circuit overhead transmission line with shunt reactors.
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Thermophysical properties of the phase change material mixtures – preliminary studies on macromolecular hydrocarbons example.
PublicationThe aim of this work is a theoretical and experimental analysis of the macromolecular hydrocarbon mixtures composition and the impact on thermophysical parameters of the phase change materials (PCM) made from these mixtures. The analysis of the current state of knowledge extended by the author’s own studies have been presented. Thermophysical characteristics of the hydrocarbons and their mixtures have been specified, in such a...
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Modification of microporous polyurethane elastomers with different types of ash—morphological, mechanical, and thermal studies
PublicationIncorporation of wood ash particles from wood gasification into microporous polyurethane elastomers has been investigated and compared to addition of commercially available microspheres resulting from coal burning. Samples were modified with 3 and 6 wt% of fillers. Structure, mechanical, and thermal properties of obtained elastomers were investigated. Incorporation of both types of ash particles decreased the density of polyurethanes...
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Studies of the Modelling Accuracy of Steam Turbine Control Systems for Diagnostic Tests of Automatic Synchronizers
PublicationOne of the important factors that affect the reliable operation of the power system and the rapid restitution after disaster is a quick and effective combining synchronous electric power facilities to operate in parallel. Hence, diagnostics of automatic synchronizers at every stage of their life, from building a prototype, through the whole life, until removing such devices from the operation, is an extremely important and responsible...
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Heat recovery from the hybrid photovoltaic tile – experimental studies with the solar light simulator
PublicationConsidering the current development of micro-cogeneration energy sources, supported by the national prosumer policy and the act on the renewable energy sources, there is a great demand for the effective solar technologies. In this area, the photovoltaic cells with a combined conversion of the solar radiation energy into the electrical and thermal energy (PV/T cells) seem to be attractive. They are already widely available and treated...
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X-Ray Diffraction, Mössbauer Spectroscopy and Magnetoelectric Effect Studies of Multiferroic Bi5Ti3FeO15 Ceramics
PublicationBi5Ti3FeO15 ceramics belongs to multiferroic class of materials. In this work it was prepared by solid-state sintering method and investigated by X-ray diffraction, Mössbauer spectroscopy, and magnetoelectric effect measurements. As it was proved by X-ray diffraction studies the single-phase Bi5Ti3FeO15 compound was obtained. The Mössbauer investigations revealed paramagnetic character of the compound at room temperature as well...
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Anisotropic mechanical behavior and auxeticity of penta-graphene: Molecular statics/molecular dynamics studies
PublicationWe investigate the mechanical properties of penta-graphene (PG), a recently proposed two-dimensional carbon allotrope using atomistic simulation techniques combined with the empirical description of interatomic interactions. We report on the dependence of its three in-plane mechanical moduli (i.e. Young's modulus, Poisson's ratio and shear modulus) on the deformation direction, strain and temperature. We show that PG displays a...
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Cooperation in Creating Innovation in Polish Small and Medium-Sized Enterprises in the Light of Empirical Studies
PublicationNowadays, sources of competitive advantage and economic development are sought in the sphere of innovation. They are at the centre of interest of representatives of the world of politics, science, and business. Moreover, they have been incorporated into governmental and international strategic development programmes. This article attempts to characterize and evaluate cooperation in creating innovation in small and medium-sized...
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Photoresponsive Amide-Based Derivatives of Azobenzene-4,4′-Dicarboxylic Acid—Experimental and Theoretical Studies
PublicationAzobenzene derivatives are one of the most important molecular switches for biological and material science applications. Although these systems represent a well-known group of compounds, there remains a need to identify the factors influencing their photochemical properties in order to design azobenzene-based technologies in a rational way. In this contribution, we describe the synthesis and characterization of two novel amides...
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Numerical studies on size effects in concrete beams. Architecture Civil Engineering Environment ACEE
PublicationW artykule przedstawiony wyniki obliczeń efektów skali w belkach betonowych podczas zginania. Zastosowano model sprężysto-plastyczny z nielokalnym osłabieniem. Rozkład wytrzymałości na rozciąganie był stochastyczny - przestrzennie skorelowany. Belki były geometrycznie podobne. Wyniki porównano z modelem efektu skali Bazanta.
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Experimental and numerical studies on the mechanical response of a piezoelectric nanocomposite-based functionally graded materials
PublicationThis work presents an experimental study of piezoelectric structures reinforced by graphene platelets, based on the concept of the functionally graded materials (FGMs). The assumed model is a rectangular beam/plate and the composition is due to the Halpin-Tsai rule. The model is also simulated in the Abaqus software which is the first time that such a structure has been modelled in an FEM package. In addition, a mathematical model...
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A new approach to β-decays studies impacting nuclear physics and astrophysics: The PANDORA setup
PublicationTheory predicts that lifetimes of β-radionuclides can change dramatically as a function of their ionization state. Experiments performed in Storage Rings on highly ionized atom have proven nuclei can change their beta decay lifetime up to several orders of magnitude. The PANDORA (Plasmas for Astrophysics, Nuclear Decay Observation and Radiation for Archaeometry) experiment is now conceived to measure, for the first time, nuclear...
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublicationA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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The Application of Dynamic Electrochemical Impedance Spectroscopy (DEIS) Technique in Corrosion and Corrosion Inhibition Studies
Publicationorrosion studies have attracted considerable interest in the areas of materials chemistry and industrial chemistry, as it affects the direct and indirect costs of industry, leading to huge economic setbacks due to the need for repair, maintenance, and even shutdowns due corrosion damage. This new volume is a comprehensive resource that presents new and up-to-date, theoretical, and experimental corrosion inhibition studies.
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Solubility enhancement of metronidazole using natural deep eutectic solvents: Physicochemical and thermodynamic studies
PublicationThis research aimed to explore the utility of natural deep eutectic solvents (NADES) as the co-solvents for slightly water-soluble metronidazole (MNZ). After testing 70 wt% (percentage by weight) aqueous mixtures of seven NADESs, it was found that MNZ had the highest solubility in water solutions of NADES composed of choline chloride (ChCl) and citric acid (CA). The solubility of MNZ (expressed as 103 mol fraction) increased with...
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Effect of underwater friction stir welding parameters on AA5754 alloy joints: experimental studies
PublicationThe water as a welding environment may generate serious technological and metallurgical problems but in certain cases, the physicochemical properties of water can be used effectively, e.g., to impart the specific properties of welded materials. The purpose of the work was verification of effectiveness of the water cooling of aluminium alloy AA5754 for various sets of technological parameters of underwater friction stir welding...
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Modified GAPI (MoGAPI) Tool and Software for the Assessment of Method Greenness: Case Studies and Applications
PublicationThe green analytical procedure index (GAPI) has been widely used to assess the greenness of different steps in analytical methodology. In the GAPI index, the different stages of the chemical analysis process are depicted using five pentagrams divided in subsections, labeled green, yellow, or red according to the degree of greenness. This GAPI tool provides a quick overview of the environmental impact and safety of the procedure....
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Comparative studies of manufacturing strategies within multi-machine production systems using simulation
PublicationZaprezentowano metodykę budowy struktur przestrzennych systemów produkcji typu gniazdowego wg zasad technologii grupowej, wykorzystując zaproponowane modele i algorytmy analizy zbiorów/relacji rozmytych. Generowane, z wykorzystaniem tych algorytmów, przebiegi procesów porównywano z przebiegami procesów w strukturach przestrzennych typu hybrydowego, tj. o wspólnych zasobach. Odnosząc się do zdefiniowanego studium przypadku, wykazano...
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The Polish perspective on adopting EU standards nitrogen removal at large WWTPs - case studies
PublicationW związku z przyjęciem nowych regulacji prawnych w zakresie usuwania azotu w dużych oczyszczalniach ścieków (>100 000 RM), potrzebne są wiarygodne i dokładne informacje na temat wymiarowania stref anoksycznych w komorach osadu czynnego. Badania zostały przeprowadzone w oczyszczalniach Gdańsk-Wschód oraz Gdynia-Dębogórze. Ich celem było porównanie szybkości denitryfikacji określonej w warunkach laboratoryjnych oraz obliczonej na...
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Studies on 16-membered azothia-and azoxythiacrown ethers as ion carriers in ion selective membranes.
Publication16-członowe azo iazoksy korony zawierające w makropierścieniu atomy siarki były badane jako nośniki jonów w jonoselektywnych elektrodach membranowych. Związki te badane były pod kątem kompleksowania metali I i II grupy układu okresowego oraz metali ciężkich i przejściowych. Wyznaczone zostały stałe trwałości kompleksów azokoron z wybranymi kationami za pomocą metody sandwiczowej. W wyniku badań potwierdzono tworzenie się silnych...
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Molecular aspects of the interaction between amphotericin B and a phospholipid bilayer: molecular dynamics studies.
PublicationAmfoterycyna B jest antybiotykiem z grupy polienów makrolidowych. Stosowany jest on w leczeniu układowych infekcji grzybowych. Wiadomo że związek ten oddziałuje ze składnikami błon lipidowych i tworzy kanały. W przedstawianej pracy prezentowane są wyniki symulacji przeprowadzonej dynamiką molekularną układu składającego się z 200 cząsteczek lipidów DMPC i jednej cząsteczki amfoterycyny ułożonej na powierzchni błony. Z przeprowadzonej...