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Search results for: REACTIVE METABOLITE
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Measurement of complex refractive index of human blood by low-coherence interferometry
PublicationIn this article, the usefulness of the optical technique for measurements of blood complex refractive index has been examined. Measurement of optical properties of human blood is difficult to perform because of its nonuniform nature. However, results of my investigation have shown the usefulness of low-coherencei nterferometry for measurement complex refractive index of human blood. Furthermore, mathematical analysis of spectrum...
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Reduction of the reaction torque of an in-line four-cylinder four-stroke engine
PublicationW pracy przedstawiono zarówno dokładne jak i uproszczone zależności na przebieg momentu reakcyjnego silnika, jedno i wielocylindrowego, przenoszonego na ramę pojazdu lub fundament. Wyprowadzono zależność na wartość przesunięcia wałków wyrównoważających zapewniającą całkowite wyeliminowanie wpływu sił bezwładności na przebieg momentu reakcyjnego w silnikach czterosuwowych czterocylindrowych. Wprowadzono kryteria doboru optymalnej...
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From Creative Thinking Techniques to Innovative Design Solutions - The Educators' Perspective
PublicationThe article presents a structure and basic tasks of a new original academic course, which was inaugurated in 2015 at the Faculty of Architecture in Gdańsk University of Technology and organized for the first year students of Spatial Planning.The title of the course was ‘Garden Cities and the Gardens in the Cities. A Course with Elements of Training Creativity’. The aim of the course was to encourage the participants to develop...
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THE CREATIVE AND SYMBOLIC FUNCTIONS OF DAYLIGHT IN THE ART MUSEUM BUILDINGS OF THE 21st CENTURY
PublicationThe paper presents the results of the study on the current extent of daylight use in contemporary buildings of art museums, focusing especially on the possibilities of aesthetic function. A case study and critical analysis were used as the research method. Selected, representative examples of museums of the 21st century are discussed with regard to the creative and functional use of daylight and the application of advanced technology....
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Changes in mussel Mytilus galloprovincialis protein profile as a reaction of water pollution
PublicationW pracy przedstawiono zmiany w profilu białkowym małża Mytilus galloprovincialis jako odpowiedź na zanieczyszczenia wody. Określono pojemność przeciwutleniającą z wykorzystaniem testu TEAC. Stwierdzono różnice w poziomie inhibicji w białku pochodzącym od małży zebranych z regionów zanieczyszczonych w stosunku do małży pochodzących z regionów czystych.Zawartość cynku i kadmu w białkach małży pochodzących z regionów zanieczyszczonych...
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Properties of a lithium solid electrolyte gas sensor based on reaction kinetics
PublicationW artykule przedstawiono zasadę działania, budowę i właściwości czujnika gazu na bazie elektrolitu stałego z mobilnymi jonami litu. Czujnik został przygotowany w technologii grubowarstwowej. Przedstawiono wyniki badań czujnika w mieszaninach gazów toksycznych.
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Properties of a polyethyleneimine-based sensor for measuring medium and high relative humidity
PublicationW artykule przedstawiono metodę przygotowania filmów polimerowych o zwiększonej odporności na działanie wody. Polietylenoimina została usieciowana w podwyższonej temperaturze. Określono optymalną kompozycję polimeru oraz temperaturę sieciowania. Czujniki rezystancyjne przygotowano metodą ''dip-coating''. Otrzymane czujniki charakteryzują się doskonałą trwałością w wysokich wilgotnościach. Elektryczne parametry czujników określono...
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Evaluation of relative humidity effects on interfacial impedance at inter-coat interfaces.
PublicationSpektroskopia impedancyjna została zastosowana jako metoda niedestrukcyjna do oceny adhezji pomiędzy polimerowymi warstwami w ochronnym systemie powłokowym. Celem badań było stwierdzenie wpływu zewnętrznej wilgotności na impedancję międzyfazową. Badano system ochrony stosowany do ochrony samochodów. Zastosowano nowy sensor do detekcji rozwarstwienia i akumulacji wody w obszarze międzyfazy. Elektrody stanowią paski przewodzącego...
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Reductive cleavage of the halogen-phosphorus and sulfur-phosphorus bonds with alkali metals
PublicationBadano redukcję chlorków kwasów tiofosforowych za pomocą: sodu lub potasu w ciekłym amoniaku i za pomocą antracenidku oraz naftalenidku potasu. Związki te ulegają, co wykazano, szybkiej redukcji do anionów >P-S- a te mogą być efektywnie utleniane siarką elementarną w ciekłym amoniaku.
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Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
PublicationTrans-Resveratrol (tRes) has been shown to have powerful antioxidant, anti-inflammatory, anti-carcinogenic, and anti-aging properties; however, its use as a therapeutic agent is limited by its rapid metabolism into its conjugated forms by UDP-Glucuronosyltransferases (UGTs). The aim of the current study was to test the hypothesis that the limited bioavailability of tRes can be improved by modifying its structure to create analogs...
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Willingness to Receive the Booster COVID-19 Vaccine Dose in Poland
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Investigation of Transmit and Receive Characteristics of Laboratory Model for the Parametric Echosounder
PublicationInvestigation and operation of devices based on nonlinear interaction of high-intensity waves have been carried out for several decades. However, it is still a new tool to study the properties of the water environment and especially the upper layers of the seabed. This paper describes the results of tests of the new device that is intended to be applied for sounding underwater areas. The device has been designed and built in collaboration with...
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Folate-directed zinc (II) phthalocyanine loaded polymeric micelles engineered to generate reactive oxygen species for efficacious photodynamic therapy of cancer
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In Silico Safety Assessment of Bacillus Isolated from Polish Bee Pollen and Bee Bread as Novel Probiotic Candidates
PublicationBacillus species isolated from Polish bee pollen (BP) and bee bread (BB) were characterized for in silico probiotic and safety attributes. A probiogenomics approach was used, and in-depth genomic analysis was performed using a wide array of bioinformatics tools to investigate the presence of virulence and antibiotic resistance properties, mobile genetic elements, and secondary metabolites. Functional annotation and Carbohydrate-Active...
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HORMONE AND METABOLIC RESEARCH
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Reaction of 4-benzylidene-2-methyl-5-oxazolone with amines, Part 2: Influence of substituents in para-position in the phenyl ring and a substituent on amine nitrogen atom on the reaction kinetics
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Ethylene photocatalytic decomposition in high temperature reaction chamber
Open Research DataData contain data logs of measurements performed on High Temperature Chamber "The Praying Mantis" coupled with SRI 8010 gas chromatograph. Measurement was performed for TiO2 irradiated by UV and under flowing of ethylene gas diluted in air and with the use of elevated temperature.
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Photocatalytic degradation of acetaldehyde in high temperature reaction chamber
Open Research DataThis dataset contains chromatograms recorded during the decomposition of acetaldehyde in a high-temperature reaction chamber under UV irradiation using TiO2 (titanium dioxide) as photocatalysts. It includes data on the influence of flow rate, TiO2 (titanium dioxide) filling the entire reactor, a thin layer of TiO2 (titanium dioxide) supported on KBr...
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Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
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Hypericum alpestre extract exhibits in vitro and in vivo anticancer properties by regulating the cellular antioxidant system and metabolic pathway of L‐arginine
PublicationConventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. This study aims to investigate the antitumor capacity of Hypericum alpestre (H. alpestre) extract in vitro and in vivo, either alone or in combination with the inhibitors of the L‐arginine/polyamine/nitric oxide...
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Fashion Practice-The Journal of Design Creative Process & the Fashion Industry
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New Writing-The International Journal for the Practice and Theory of Creative Writing
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Novel 2-alkythio-4-chloro-N-[imino(heteroaryl)methyl]benzenesulfonamide Derivatives: Synthesis, Molecular Structure, Anticancer Activity and Metabolic Stability
PublicationA series of novel 2-alkythio-4-chloro-N-[imino-(heteroaryl)methyl]benzenesulfonamide derivatives, 8–24, were synthesized in the reaction of the N-(benzenesulfonyl)cyanamide potassium salts 1–7 with the appropriate mercaptoheterocycles. All the synthesized compounds were evaluated for their anticancer activity in HeLa, HCT-116 and MCF-7 cell lines. The most promising compounds, 11–13, molecular hybrids containing benzenesulfonamide...
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Acridinone antitumor agents, C-1305 and C-1299 are metabolized rather by flavin-containing monooxygenases and UDP-glucuronosyltransferases than cytochromes P450
PublicationStwierdzono, że to monooksygenazy flawinowe, a nie enzymy cytochromu P450, są głównymi enzymami frakcji mikrosomalnej, odpowiedzialnymi za detoksyfikacyjny metabolizm dwóch badanych pochodnych triazoloakrydonu. Dodatkowo C-1305 ulega sprzęganiu w czasie drugiej fazy metabolizmu z kwasem glukuronowym do postaci O-glukuronidu
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The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension
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Products of Vitamin D3 or 7-Dehydrocholesterol Metabolism by Cytochrome P450scc Show Anti-Leukemia Effects, Having Low or Absent Calcemic Activity
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CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
PublicationWe examine whether CYP3A4 overexpression influences the rate and pattern of antitumor imidazoacridinone C-1311 metabolism, in relation to the impact of this overexpression on cell cycle progression and final cellular response of CHO cells following C-1311 treatment. Methods: Three CHO cell lines: CHO-WT, wild type, CHO-HR, overexpressing cytochrome P450 reductase (CPR) and CHO-HR-3A4, coexpressing CPR and CYP3A4 were applied....
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Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism
PublicationIn spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...
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Metabolomic and antioxidant properties of different varieties and origins of Dragon fruit
PublicationDragon fruit has appealed much concern from consumers as a novelty fruit with potent nutritional and medicinal benefits. Dragon fruit quality warrants comprehensive evaluation, based on the contents of pigments and health- promoting natural compounds in different varieties. This study was aimed to evaluate the differences among dragon fruit varieties extracted with methanol–water (CD3OD-D2O) and methanol (CD3OD) by proton nuclear magnetic...
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Synthesis of some optically active terpenoid-derived thioamides
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Design of a simple modular active power electronic transformer
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Predictive control system of the shunt active power filter
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New control system of the shunt active power filter
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Research and applications of active bearings: A state-of-the-art review
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Active farmsteads are year-round strongholds for farmland birds
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Research and applications of active bearings: A state-of-the-art review
PublicationControllable/active bearings are mainly associated with active magnetic bearings (AMBs), whereas active bearing control is also found in many types of bearings, e.g. fluid, gas and hybrid bearings. The article presents a review of the literature describing the structure and results of studies of active bearings. Active control brings a number of benefits resulting in the fact that their use as a support for rotors becomes increasingly...
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Semantic memory knowledge acquisition through active dialogues
PublicationSzereg zagadnień językowych nie może zostać rozwiązany bez pamięci semantycznej zawierającej opisy cech obiektów, Automatyczne tworzenie tego rodzaju pamięci jest wielkim wyzwaniem nawet dla prostych obszarów dziedzinowych. Implementacja pamięci semantycznej opartej na reprezentacji wiedzy poprzez powiązania obiektu z jego cechami pokazuje ciekawe zastosowania które nie zostały dotychczas zademonstrowane poprzez bardziej wyszukane...
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Active Damping of Impulse-Excited Flexible Plate Vibration
PublicationArtykuł prezentuje metodę aktywnego tłumienia drgań podatnej płytki wzbudzanych impulsowo. Układ sterowania składa się z aktywych wzbudników piezoelektrycznych przymocowanych do przedmiotu. Efektywnośc metody została potwierdzona badaniami eksperymentalnymi.
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Active Dynamic Thermography - Problems of implementation in medical diagnostics
PublicationW pracy przedstawiono wybrane problemy implementacji aktywnej termografii termicznej w aplikacjach medycznych. Podano przykłady związane z diagnostyką raka piersi i głębokości oparzeń.
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Semi-adaptive feedback active control of MRI noise
PublicationA feedback controller is proposed for cancellation of magnetic resonance imaging (MRI) noise. The design of the controller takes into account specific features of the MRI noise signal. Simulation results show that a considerable rejection rate of the MRI noise can be obtained.
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Multichannel self-optimizing active noise control scheme
PublicationThe problem of cancellation of a nonstationary sinusoidal interference, acting at the output of an unknown multivariable linear stable plant, is considered. The proposed cancellation scheme is a nontrivial extension of the SONIC (self-optimizing narrowband interference canceller) algorithm, developed earlier for single-input, single-output plants. In the important benchmark case - for disturbances with randomwalk-type amplitude...
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Semi complex navigation with an active optical gesture sensor
PublicationThis paper presents the methods of diversified touchless interactions between a user and a mobile platform utilizing the optical gesture sensor. The sensor uses 8 photodiodes to measure the reflected light in the active mode (using embedded LEDs) or it measures shadows caused by fingers in the passive mode. Several algorithms were implemented: automatic mode switching, adaptive illumination level compensation, resolution improvements...
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Problems of Active Dynamic Thermography Measurement Standardization in Medicine
PublicationReliability of thermographic diagnostics in medicine is an important practical problem. In the field of static thermography, a great deal of effort has been made to define the conditions for thermographic measurements, which is now the golden standard for such research. In recent years, there are more and more reports on dynamic tests with external stimulation, such as Active Dynamic Thermography, Thermographic Signal Reconstruction...
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Robust algorithm for active feedback control of narrowband noise
PublicationThe problem of active control of narrowband acoustic noise is considered. It is shown that the proposed earlier feedback control algorithm called SONIC (self-optimizing narrowband interference canceller), based on minimization of the L2-norm performance measure, can be re-derived using the L1 approach. The resulting robust SONIC algorithm is more robust to heavy-tailed measurement noise, such as the αlpha-stable noise, than the...
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Active feedback noise control in the presence of impulsive disturbances
PublicationThe problem of active feedback control of a narrowband acoustic noise in the presence of impulsive disturbances is considered. It is shown that, when integrated with appropriately designed outlier detector, the proposed earlier feedback control algorithm called SONIC is capable of isolating and rejecting noise pulses. According to our tests this guarantees stable and reliable operation of the closed-loop noise cancelling...
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Removal of Pharmaceutically Active Compounds in Sequencing Batch Reactor
PublicationIn recent years, considerable attention was paid to the presence of organic micro-pollutants such as Active Pharmaceutical Ingredients (API) in the aquatic environment due to their negative impact on public health and aquatic ecosystems. Numerous papers have pointed out API presence as common constituents of effluents from Wastewater Treatment Plants (WWTPs). This is the result of various efficiencies of API removal by conventional...
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Noise performance of continuous-time active-RC filters.
PublicationW pracy przedstawiono metodę analizy właściwości szumowych filtrów aktywnych RC czasu ciągłego. Prezentowana procedura wykorzystuje model integratorowy, z odpowiednim dla tej klasy filtrów opisem macierzowym. Dokładność osiągniętych wyników teoretycznych dla przykładowego filtru potwierdzono rezultatami otrzymanymi przy pomocy symulatora SPICE.
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Active and Dynamic Graphical Code for Object Identification in Healthcare
PublicationA new approach for item marking using two dimensional discrete graphics markers. Proposed solution allow o change the code rapidly, upon request and in the case of thermal markers make the code invisible for unauthorized observers. Connecting the proposed codes with wearable multmedial platform such as eGlasses can create new possibilities in human-environment interaction.
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Active management of equipment cooling in hoteling data centers
PublicationHoteling data centers are designated for housing computing and storage units of many, usually small customers, as opposed to traditional data centers supporting own computing and storage resources of a bigger company. One of the services to be provided to consumer’s equipment is cooling. Cooling in data centers is prevalently achieved by circulating air in computer room. Efficient cooling requires delivering cold air from central...
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An active electrode for mixed measurement techniqes, with application to EIT
PublicationW pracy przedstawiono budowę elektrody aktywnej wraz z opisem procedur pomiarowych prowadzących do poprawy stosunku sygnał-szum. Elektroda zbudowana jest w technice cyfrowo analogowej.