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Search results for: IBUPROFEN AND ITS METABOLITES
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The Application of Metabolomics in Forensic Science with Focus on Forensic Toxicology and Time-of-Death Estimation
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A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
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Serum Cholesteryl Ester Transfer Protein (CETP) and Sortilin (SORT) in Patients with Psoriasis with Relation to Systemic Treatment
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Potential Predictive Value of Serum Pentraxin 3 and Paraoxonase 1 for Cardiometabolic Disorders Development in Patients with Psoriasis—Preliminary Data
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Systemic Effects of Radiotherapy and Concurrent Chemo-Radiotherapy in Head and Neck Cancer Patients—Comparison of Serum Metabolome Profiles
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Changes in the Secretion of Melatonin and Selected Adipokines during the Progression of Parkinson’s Disease—Preliminary Studies
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The Influence of Winter Swimming on Oxidative Stress Indicators in the Blood of Healthy Males
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HBM4EU Chromates Study: Urinary Metabolomics Study of Workers Exposed to Hexavalent Chromium
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Potential Use of Thalidomide in Glioblastoma Treatment: An Updated Brief Overview
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How Does In Vitro Digestion Change the Amount of Phenolics in Morus alba L. Leaf? Analysis of Preparations and Infusions
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Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
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Optimization of Cyclodextrin-Assisted Extraction of Phenolics from Helichrysum italicum for Preparation of Extracts with Anti-Elastase and Anti-Collagenase Properties
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Glycerol and Natural Deep Eutectic Solvents Extraction for Preparation of Luteolin-Rich Jasione montana Extracts with Cosmeceutical Activity
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Genotoxic properties of glucosinolates and isothiocyanates present in Brassica vegetables
PublicationThe bioactive phytochemicals found in Brassica vegetables, in this number glucosinolates (GLS), as well as products of their degradation such as isothiocyanates (ITC) and indoles, are regarded as the most promising chemopreventive compounds. These secondary metabolites display stron antibiological activity and constitute defence system preventing the development of agrophages attacking Brassica plants. Such properties suggest...
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ITL - International Journal of Applied Linguistics (Belgium)
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Ius Publicum
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IOS Press
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Effect of Some Sulphur Additives on The Degradation of 9Cr-1Mo Steel After Its 10 Years Service in The CCR Platforming Unit
PublicationThe work shows the results of the tests of 9Cr-1Mo steel, which was for 10 years operated in the CCR platforming unit in Group Lotos SA in Gdańsk, and then in the laboratory was sulphidised during 166 h at a temperature of 600 °C. Sulphidation was performed in a mixture of H2-H2S gases at the vapour pressure of sulphur 4.1·10-14 atm, so the order of magnitude of vapour pressure was less than that of the dissociation pressure of...
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Destructiveness of Profits and Outlays Associated with Operation of Offshore Wind Electric Power Plant. Part 1: Identification of a Model and its Components
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Genotoxic effects of antitumor 1-nitroacridines C-857 and its novel analoque 4-methyl-1-nitroacridine C-1748
Publication4-podstawione 1-nitroakrydyny reprezentują nową grupę pochodnych akrydyny zsyntetyzowanych na Politechnice Gdańskiej. W przeprowadzonych badaniach nad pochodnymi C-1748 i C-857 zastosowano dwie metody badawcze: test kometowy oraz zmodyfikowany test mikrojąderkowy (CBMN assay). W teście kometowym wykazano wzrost uszkodzeń DNA w zależności od czasu i stężenia badanych pochodnych 1-nitroakrydyny. Badania aberracji chromosomalnych...
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How do sterols determine the antufungal activitiy of amphotericin B? Free energy of binding between the drug and its membrane targets.
PublicationAmphotericin B (AmB) is a well-known polyene antibiotic used to treat systemic fungal infections. It is commonly accepted that the presence of sterols in the membrane is essential for the AmB biological activity, that is, for the formation of transmembrane ion channels. The selective toxicity of AmB for fungal cells is attributed to the fact that it is more potent against fungal cell membranes containing ergosterol than against...
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Salt saturated single drop microextraction of gold from water samples and its determination by graphite furnace atomic absorption spectrometry
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Capillary gas chromatography using a -cyclodextrin forenantiomeric separation of methylamphetamine, its precursors andchloro intermediates after optimization of the derivatization reaction
PublicationtThe enantiomeric ratio of methylamphetamine (MAMP) is closely related to the optical activity of precur-sors and reagents used for the synthesis and this knowledge can provide useful information concerningthe origins and synthetic methods used for illicit manufacture. The information can be utilized for reg-ulation of the precursors and investigation of the manufacturing sources but this requires analyticalprocedures to determine...
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Biogeochemia selenu i jego monitoring w materiałach biologicznych pochodzenia ludzkiego = Selenium biochemistry and its monitoring in biological samples
PublicationNa przestrzeni ostatnich kilkudziesięciu lat selen stał się przedmiotem intensywnych badań naukowych w wielu dyscyplinach nauki. Najczęściej poruszanymi zagadnieniami są aspekty związane z biochemią, geologią, toksykologią, wykorzystaniem przemysłowym selenu oraz jego wpływem na organizmy żywe. Powodem szczególnego zainteresowania tym pierwiastkiem jest niewielka różnica pomiędzy jego poziomem niezbędnym a toksycznym oraz szereg...
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Identification and characterization of the Indian Yellow dyestuff and its degradation products in historical oil paint tube by liquid chromatography mass spectrometry
PublicationAn analytical protocol for identification of dyes using reversed phase liquid chromatography-mass spectrometry with atmospheric pressure electrospray ionization (LC-ESI/MS) is presented. The developed method has been successfully applied in identification of euxanthic acid and euxanthone, the main components of the Indian Yellow dye in a historical oil paint tube produced by Richard Ain`es, a recognizable French company supplying...
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Heart Rate Asymmetry, Its Compensation, and Heart Rate Variability in Healthy Adults during 48-h Holter ECG Recordings
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Supplementation of beer with Pinus sylvestris L. shoots extracts and its effect on fermentation, phenolic content, antioxidant activity and sensory profiles
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Influence of an Electronic Structure of N-TiO2 on Its Photocatalytic Activity towards Decomposition of Acetaldehyde under UV and Fluorescent Lamps Irradiation
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In vitro affinity of Deinococcus radiodurans MutS towards mismatched DNA exceeds that of its orthologues from Escherichia coli and Thermus thermophilus
PublicationThe mismatch binding protein MutS is responsible for the recognition of mispaired and unpaired bases, which is the initial step in DNA repair. Among the MutS proteins most extensively studied in vitro are those derived from Thermus thermophilus, Thermus aquaticus and Escherichia coli. Here, we present the first report on the in vitro examination of DNA mismatch binding activity of MutS protein from Deinococcus radiodurans and confront...
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Complete Nucleotide Sequence of the pCTX-M3 Plasmid and Its Involvement in Spread of the Extended-Spectrum β-Lactamase GeneblaCTX-M-3
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Early farming settlement of the marginal zone of loess uplands and its palaeoenvironmental context – a case study of the Iłża Piedmont (S Poland)
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Recent advances in electrochemically surface treated titanium and its alloys for biomedical applications: A review of anodic and plasma electrolytic oxidation methods
PublicationNowadays, titanium and its alloys are widely used materials in implantology. Nevertheless, the greatest challenge is still its appropriate surface treatment in order to induce optimal properties, which facilitates formation of a permanent bond between the implant and human tissue. The use of electrochemical treatment such as anodic oxidation or plasma electrolytic oxidation allows for the production of porous coating that mimics...
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
PublicationProliferation and expansion of leukemia is driven by leukemic stem cells (LSCs). Multidrug resistance (MDR) of LSCs is one of the main reasons of failure and relapses in acute myeloid leukemia (AML) treatment. In this study, we show that maintaining HL-60 at low cell culture density or applying a 240-day treatment with anthrapyridazone (BS-121) increased the percentage of primitive cells, which include LSCs determining the overall...
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Thermal Instability of Choline Chloride-Based Deep Eutectic Solvents and Its Influence on Their Toxicity─Important Limitations of DESs as Sustainable Materials
PublicationDeep eutectic solvents (DESs) have become a hot topic in many branches of science due to their remarkable properties. They have been studied in a wide variety of applications. In particular, choline chloride (ChCl)-based DESs are one of the most commonly used representatives of these fluids. Nevertheless, in order to apply DESs in some fields, it is essential to guarantee their stability, reusability, and biocompatibility. In this...
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Surface modification of PMMA polymer and its composites with PC61BM fullerene derivative using an atmospheric pressure microwave argon plasma sheet
PublicationThis paper presents the results of experimental investigations of the plasma surface modification of a poly(methyl methacrylate) (PMMA) polymer and PMMA composites with a [6,6]-phenyl-C61-butyric acid methyl ester fullerene derivative (PC61BM). An atmospheric pressure microwave (2.45 GHz) argon plasma sheet was used. The experimental parameters were: an argon (Ar) flow rate (up to 20 NL/min), microwave power (up to 530 W), number...
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Activity of Polish unifloral honeys against pathogenic bacteria and its correlation with colour, phenolic content, antioxidant capacity and other parameters.
PublicationThe use of honey as an antimicrobial agent gains importance due to often ineffectiveness of conventional treatment. However, activity of honey depends mainly on its botanical and geographical origin. To date, antimicrobial potential of Polish honeys has not yet been entirely investigated. In this study, 37 unifloral samples of 14 honey types (including rare varieties) from Poland were analysed and compared with manuka honey. The...
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Novel composite of Zn/Ti-layered double hydroxide coupled with MXene for the efficient photocatalytic degradation of pharmaceuticals
PublicationIn the present study, a hybrid photocatalyst of Zn/Ti layered double hydroxide (LDH) coupled with MXene – Ti3C2 was synthesized for the first time and applied in photocatalytic degradation of acetaminophen and ibuprofen, two commonly present in the natural environment and prone to accumulate in the aquatic ecosystem pharmaceuticals. The effect of MXene content (0.5 wt%, 2.5 wt%, and 5 wt%) on the photocatalytic activity of LDH/MXene...
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Surface activation by cyclic polarization in 1M HCl and its effects on the electrochemical response of CB-PLA 3D printed electrodes
Open Research DataThe dataset contains the electrochemical studies performed for surface activation of the CB-PLA 3D printed electrodes by electrolysis in 1M HCl solution. The studies were performed after treatment at different polarization ranges, as labeled in subfolder names. For each electrode the consecutive studies describe different samples, as labeled in subfolders:...
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The AFM micrographs of vanadium oxides thin films deposited on quartz glass - the influence of the thickness of the thin film on its morphology
Open Research DataThe DataSet contains the atomic force microscope images of the surface of vanadium oxide thin films. The thin films were obtained by the sol-gel method. The information about sol synthesis is described in the Journal of Nanomaterials. The thin films with different thicknesses (1, 2 or 3 AsP layers) were deposited on a quartz glass substrate and were...
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Nuclear Magnetic Resonance Metabolomics Reveals Qualitative and Quantitative Differences in the Composition of Human Breast Milk and Milk Formulas
PublicationCommercial formula milk (FM) constitutes the best alternative to fulfill the nutritional requirements of infants when breastfeeding is precluded. Here, we present the comparative study of polar metabolite composition of human breast milk (HBM) and seven different brands of FM by nuclear magnetic resonance spectroscopy. The results of the multivariate data analysis exposed qualitative and quantitative differences between HBM and...
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Electrical and optical characterization of ITO thin films
PublicationW pracy przestawiono wyniki badań tlenku cyny domieszkowanego indem (ITO) pod kątem zastosowania jako przezroczyste elektrody. opisano metody pomiarów wybranych właściwości elektrycznych i optycznych. cienką warstwę ito, naniesioną na szklane podłoże, wykonano metodą rozpylania magnetronowego.
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Analiza awarii masztów na STS Pogoria
Publication''Pogoria'' - żaglowiec szkolny uczestniczyła w trakcie ''TALL SHIP RACE 2009'' w rejsie na trasie Gdynia-St.Petesburg. W dniu 7 lipca 2009 roku w trakcie bezpośredniej rywalizacji z płynącą obok siostrzaną - nieco młodszą - ''Kaliakrą'' (jacht płynął lewym halsem, kursem 055, przy wietrze ESE o sile 6B), podczas nadmiernego wyostrzenia do wietru, nastąpiło złamanie fokmasztu, a w konsekwencji - pozostałych dwóch masztów. W artykule...
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Diagnostyczne pasma IRS po modyfikacji bursztynu
PublicationBadania spektroskopowe naturalnego, modyfikowanego i prasowanego sukcynitu (bursztynu bałtyckiego), przygotowanego w określony sposób, oraz próbek zebranych w trakcie prowadzonych badań, pozwoliły z dużym prawdopodobieństwem wskazać diagnostyczne odcinki widm, pozwalające odróżnić materiał naturalny od substancji poddanych obróbce innej niż mechaniczna. Są to w różny sposób wykształcone pasma (w cm-1) w okolicach: 1642 i 888, 1012...
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Comparison of Overcurrent Responses of 2G HTS Tapes
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SYSTEM IDENTYFIKACJI SZUMÓW RTS TRANSOPTORÓW CNY17
PublicationW artykule opisano zaprojektowany i wykonany system do identyfikacji szumów wybuchowych (RTS – Random Telegraph Signal) występujących w transoptorach typu CNY17. Z metod umożliwiających ocenę parametrów szumów wybuchowych wybrano do realizacji metodę Wzorów Obrazów Szumów – WOS (ang. Noise Scattering Patterns – NSP), która w sposób bardzo prosty pozwala na rozpoznawanie szumów o rozkładach wartości chwilowych gaussowskich i niegaussowskich....
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Concentration in ICTs sector - cross country analysis
PublicationIn the chapter below, the author present inequalities in sector of new information and communication technologies. Having in mind inequalities we can also discuss concentration issues, and the concentration itself is a problem to which the author refers on first place. The paper is organized as following: first basic measures of concentration are defined, after we can read a discussion referring to concentration in ICTs sector...
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Traffic Modeling in IMS-based NGN Networks
PublicationIn the modern world the need for accurate and quickly delivered information is becoming more and more essential. In order to fulfill these requirements, next generation telecommunication networks should be fast introduced and correctly dimensioned. For this reason proper traffic models must be identified, which is the subject of this paper. In the paper standardization of IMS (IP Multimedia Subsystem) concept and IMS-based NGN...
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Warstwa serwerów usług dla architektury IMS
PublicationArtykuł przedstawia warstwę serwerów usług oraz jej rolę w technologii IP Multimedia Subsystem. Szczególnie istotnym aspektem dla tej pracy jest spojrzenie na dwie cechy architektury IMS, dzięki którym jest ona tak interesująca z punktu widzenia usługowego. Pierwszą z nich jest fakt rozdzielenia warstwy transportowej od warstwy usługowej. Ten cel przyświecał twórcom standardu od samego początku i można powiedzieć, że jest on trzonem...
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Design of a Multidomain IMS/NGN Service Stratum
PublicationThe paper continues our research concerning the Next Generation Network (NGN), which is standardized for delivering multimedia services with strict quality and includes elements of the IP Multimedia Subsystem (IMS). A design algorithm for a multidomain IMS/NGN service stratum is proposed, which calculates the necessary CSCF servers CPU message processing times and link bandwidths with respect to the given maximum values of mean...
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Injection of charge into the archetype organics hole transporting material TPD at the electrical contacts with ITO and Al
PublicationW pracy zaprezentowano dokładną analizę charakterystyk polowo-prądowych jednowarstwowych układów kwarc/ITO/TPD/Al oraz kwarc/Al1/TPD/Al2, zawierających próżniowo naparowane warstwy pochodnej diaminy (TPD) używane powszechnie jako materiał przewodzący dziury w organicznych diodach elektroluminescencyjnych. Prądy są zdominowane przez iniekcję dziur niezależnie od polaryzacji kontaktów elektrycznych. Oprócz oczywistej asymetrii w...