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Search results for: MTA PHOSPHORYLASE
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Mariusz Jaczewski dr inż.
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Automotive Validation Functions for On-line Test Evaluation of Hybrid Real-time Systems
PublicationThe aim of this paper is to present the means of black-box on-line test evaluation for hybrid real-time systems. The described procedures can be used for the model-based testing process so as to improve its effectiveness. In particular, intelligent automotive validation functions are considered, which are divided into different types depending on the nature of the evaluated issue. All provided definitions are specified on the meta-model...
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Metrology and Instruments [ Метрологія та прилади / Metrologia ta prylady ]
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Mariusz Rudnicki mgr inż.
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Analiza statyczna konstrukcji przęseł oraz podwieszenia mostu MA 21 przez rzekę Odrę w ramach budowy Autostradowej Obwodnicy Wrocławia
PublicationCelem opracowania jest niezależna weryfikacja obliczeń statycznych konstrukcji mostu Rędzińskiego we Wrocławiu, dobranie sił w wieszakach oraz weryfikacja przyjętych założeń konstrukcyjnych. W ramach prac wykonano dwa modele: uproszczony oraz złożony. W oparciu o modele przeprowadzono analizę statyczną oraz wytrzymałościową.
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Ocena nośności ław podpór nr 23, 24, 25. Most MA-91 przez rzeką Wisłę w ciągu autostrady A1
PublicationW pracy przeprowadzono ocenę nośności ław podpór mostu MA-91 przez rzekę Wisłę
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Novel steroid sulfatase inhibitors based on N ‐thiophosphorylated 3‐(4‐aminophenyl)‐coumarin‐7‐O‐sulfamates
PublicationIn the present work, we described convenient methods for the synthesis ofN-thiophosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates as steroid sulfatase(STS) inhibitors. To design the structures of the potential STS inhibitors, molecularmodeling techniques were used. A computational docking method was used to deter-mine the binding modes of the synthesized inhibitors as well as to identify potentialinteractions between specified...
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Katarzyna Wojan dr hab.
PeopleDr habil., assiociate professor, Polish linguist, lexicographer, bibliographer; Finnish, Russian, Slavonic languages; confrontative linguistics, lexicology, lexicography, history of Polish lexicography, translation studies, intercultural communication, reception of Polish literature abroad, translations Editor-in-Chief of the Journal "Studia Rossica Gedanensia" (annual)
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Opinia naukowo-techniczna Analiza posadowienia obiektu MA‐09 w związku ze zmianą fundamentowania z pali wielkośrednicowych na pale prefabrykowane
PublicationPrzeanalizowano projekt zamienny posadowienia na palach prefabrykowanych obiektu mostowego MA-09 przez Wisłę wzdłuż drogi S7 w Kiezmarku. Na podstawie przeprowadzonych analiz stwierdzono, że zaproponowane zamienne rozwiązanie posadowienia podpór mostu jest możliwe do zastosowania i zapewni bezpieczeństwo posadowienia obiektu.
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Z oceny dokumentacji dotyczącej faz budowy pylonu mostu MA 21 przez rzekę Odrę w ramach budowy Autostradowej Obwodnicy Wrocławia
PublicationWspornikowa budowa pylonów metodą betonowania z wykorzystaniem deskowań przestawnych wymaga określenia technologii postępowania, uwzględniającej naprężenia i deformacje struktury w kolejnych fazach budowy. Opiniowane opracowanie zawiera opis i analizę poszczególnych faz z uwzględnieniem procesu dojrzewania betonu.Celem opinii jest krytyczna ocena przedstawionego materiału jako potwierdzenie jego prawidłowości lub wniesienie poprawek.W...
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EFFECTS OF DOPING ON STRUCTURE AND PHASE TRANSITION OF HIGH TEMPERATURE PROTON CONDUCTOR LaNb1-xMxO4-σ (M=As, Sb, V, Ta AND X=0,05 TO 0,3)
PublicationIn this work synthesis of lanthanum orthoniobate has been done. Doping by arsenic, antimony, vanadium or tantalum in 5% to 30% have been introduced. The relationship between doping type and percentage and structural properties of the material have been investigated.
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Jakub Miler dr inż.
PeopleAcademic career: 2000: Master of Science - Gdansk University of Technology, Faculty of Electronics, Telecommunications and Informatics, thesis "Computer system for supporting risk management in a software engineering project", supervisor prof. Janusz Górski 2005: PhD - Gdansk University of Technology, Faculty of Electronics, Telecommunications and Informatics, thesis "A Method of Software Project Risk Identification and Analysis",...
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Supporting Cybersecurity Compliance Assessment of Industrial Automation and Control System Components
PublicationThe chapter presents a case study demonstrating how security requirements of an Industrial Automation and Control System (IACS) component can be represented in a form of Protection Profile that is based on IEC 62443 standards and how compliance assessment of such component can be supported by explicitly representing a conformity argument in a form based on the OMG SACM meta-model. It is also demonstrated how an advanced argument...
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Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
PublicationEndometrial cancer (EC) is the second most common cancer in women. A large number of human cancers exhibit dysregulation of microRNA expression including EC. MiR-15b/16–2 is one of the best-known miRNA clusters that is expressed in many types of cancer tissues. Herein, we analyzed the expression of individual miR-15b/16–2 cluster members, its paralogues, and their target network analysis, as well as their prognostic significance...
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Role of miR-15b/16–2 cluster network in endometrial cancer: An in silico pathway and prognostic analysis
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Beata Krawczyk-Bryłka dr
PeoplePsycholog, doktor nauk humanistycznych w dziedzinie zarządzania, adiunkt w Katedrze przedsiębiorczości. 2018 - 2021: Kierownik projektu NCN: „Efektuacyjny model zespołu przedsiębiorczego. Jak działają przedsiębiorcze zespoły odnoszące sukces" od 2016: Quality Standards Lead filaru People management & personal development na studiach MBA Politechniki Gdańskiej 2008 – 2012: Prodziekan ds kształcenia Wzydziału Zarządzania i Ekonomii...
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Badania nad wykorzystaniem rekombinantowego białka MutS do wykrywania muta-cji punktowych.**2002, ????s. ???rys. ??? tab. bibliogr.???poz. maszyn. Rozprawa doktorska 10.04.2002, P. Gdań. Wydz. Chem. Promotor: prof. dr hab. J. Kur.
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NOR-STA n/d
ProjectsProject realized in Faculty of Electronics, Telecommunications and Informatics according to UDA-POIG.01.03.01-22-142/09 agreement from 2009-09-15
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Hsi-An Chiao Tung Ta Hsueh/Journal of Xi'an Jiaotong University
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Rukopysna ta Knyzhkova Spadshchyna Ukrainy-Manuscript and Book Heritage of Ukraine
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Derivation of Executable Test Models From Embedded System Models using Model Driven Architecture Artefacts - Automotive Domain
PublicationThe approach towards system engineering compliant to Model-Driven Architecture (MDA) implies an increased need for research on the automation of the model-based test generation. This applies especially to embedded real-time system development where safety critical requirements must be met by a system. The following paper presents a methodology to derive basic Simulink test models from Simulink system models so as to execute them...
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Opracowanie opinii technicznej w zakresie występowania iniektu wewnątrz wskazanych przez Zleceniodawcę kanałów kablowych mostu MA-09 w ciągu drogi S7
PublicationCelem opracowania jest ocena występowania iniektu wewnątrz wskazanych przez Zleceniodawcę kanałów kablowych mostu MA-09 realizowanego w ramach zadania „Budowa drogi S-7 Gdańsk (A-1) – Elbląg (S-22) odc. Koszwały (DK nr 7, W. Koszwały) - Elbląg (z węzłem Kazimierzowo) z podziałem na 2 części. Zadanie 1: Koszwały – Nowy Dwór Gdański“. Zakres opracowania obejmuje: • zapoznanie się z dokumentacją techniczną obiektu, • wizję lokalną, •...
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Data for meta-analysis on interversions reducing car use
Open Research DataThis dataset contains the results of a meta-analysis of reported interventions reducing car use. To standardise intervention effects reported in different scales, the Hedges’ g effect size measure was used (ratio of raw difference in samples’ means and pooled standard deviation). The standardised studies outcomes, along with overall outcome, were...
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Jaki uniwersytet, taka internacjonalizacja, czyli o tym, jak i dlaczego kwestia modelu uniwersytetu ma wpływ na jego internacjonalizację na przykładzie Polski
PublicationDyskurs w szkolnictwie wyższym na temat modelu uniwersytetu nie odnosi się bezpośrednio do internacjonalizacji, jednakże rola i postrzeganie umiędzynarodowienia w środowisku akademickim jest różne. W środowisku wspierającym tradycyjny model uczelni internacjonalizacja traktowana jest implicite. Wynika z wolności nauki i badań oraz dążeniu do zgłębiania i zdobywania wiedzy (nauka nie ma narodowości, L. Pasteur). Jako taka nie...
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Millimeter Wave Negative Refractive Index Metamaterial Antenna Array
PublicationIn this paper, a novel negative refractive index metamaterial (NIM) is developed and characterized. The proposed metamaterial exhibits negative effective permittivity (εeffe) and negative effective permeability (µeffe) at millimeter wave frequency of 28GHz. This attractive feature is utilized to enhance the gain of a microstrip patch antenna (MPA). Two thin layers of 5 5 subwavelength unit cell array of NIM are placed above a...
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A Comprehensive Survey on Antennas On-Chip Based on Metamaterial, Metasurface, and Substrate Integrated Waveguide Principles for Millimeter-Waves and Terahertz Integrated Circuits and Systems
PublicationAntennas on-chip are a particular type of radiating elements valued for their small footprint. They are most commonly integrated in circuit boards to electromagnetically interface free space, which is necessary for wireless communications. Antennas on-chip radiate and receive electromagnetic (EM) energy as any conventional antennas, but what distinguishes them is their miniaturized size. This means they can be integrated inside...
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Immunosuppressive properties of amino acid and peptide derivatives of mycophenolic acid
PublicationMycophenolic acid (MPA) was coupled with amino acids and biologically active peptides including derivatives of tuftsin to modify its immunosuppressive properties. Both amino acid unit in the case of simple MPA amides and modifications within peptide moiety of MPA - tuftsin conjugates influenced the observed activity. Antiproliferative potential of the obtained conjugates was investigated in vitro and MPA amides with threonine methyl...
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Metoda wektorowa pomiaru impedancji pętli zwarciowej w obecności załóceń. Autoreferat rozprawy doktorskiej.**2002, 16 s. 11 rys. bibliogr. 12 poz. ma szyn.
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Pedagogika, Psihologia ta Mediko-Biologicni Problemi Fizicnogo Vihovanna i Sportu
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Quantitative fluorescent determination of DNA – Ochratoxin a interactions supported by nitrogen-vacancy rich nanodiamonds
PublicationOchratoxin A (OTA) is a hazardous contaminant of a large variety of plant and animal originated food. Herein, we report an interaction of OTA with calf thymus DNA (ct DNA) on the nanodiamond surface. We employed multispectroscopic techniques to elucidate the binding mechanism of OTA with ct DNA. The fluorescence and UV–Vis spectroscopy results show that OTA binds to ds ct DNA and forms complexes. We obtained the binding constants...
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Adam Dziekoński dr inż.
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Marek Izydorek prof. dr hab.
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublicationBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Synthesis and biological activity of ester derivatives of mycophenolic acid and acridines/acridones as potential immunosuppressive agents
PublicationImproved derivatives of mycophenolic acid (MPA) are necessary to reduce the frequency of adverse effects, this drug exerts in treated patients. In this study, MPA was coupled with N-(x-hydroxyalkyl)-9-acridone-4-carboxamides or N-(x-hydroxyalkyl)acridine-4-carboxamides to give respective ester conjugates upon Yamaguchi protocol. This esterification required protection of phenol group in MPA. Designed conjugates revealed higher...
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Opinia o nowej technologii nazwanej „Technologia frezowania 3D delikatnych tworzyw sztucznych”, planowanej do wdrożenia w ramach inwestycji na którą ma być udzielony kredyt technologiczny.
PublicationOpinia dotyczyła projektu zatytułowanego "Wdrożenie innowacyjnej technologii w zakresie frezowania 3D delikatnych tworzyw sztucznych", który stanowi przedmiot wniosku o udzielenie kredytu technologicznego. Opiniowano nowość technologii o nazwie „Technologia frezowania 3D delikatnych tworzyw sztucznych”. Opinię wystawił Wydział Mechaniczny Politechniki Gdańskiej. Podmiotem wnioskującym sporządzenie opinii oraz wdrażającym nową technologię...
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Revista Vasca de Gestión de Personas y Organizaciones Públicas / Pertsonak eta Antolakunde Publikoak Kudeatzeko Euskal Aldizkaria
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Analogowe filtry CMOS OTA-C czasu ciągłego realizowane w strukturach pro- gramowalnych.**2002, s. 7-113, 95 rys. 12 tab. maszyn. Rozprawa doktorska ( 22.10.2002 ) PG Wydz. Elektr. Telekom. i Informat. Promotor: prof. dr hab. inż. Michał Białko
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Magdalena Brzozowska-Woś dr hab. inż.
PeopleMagdalena Brzozowska-Woś is a graduate of the Faculty of Management and Economics of the Gdańsk University of Technology (specialization: management systems). She is also a graduate of Postgraduate Studies in Advertising (Faculty of Management and Economics, GUT) and Postgraduate Studies in Public Relations (SWPS University of Humanities and Social Sciences). In the years 2000-2003, she cooperated with Panorama Internet sp. z o....
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The Interaction of Heptakis (2,6-di-O-Methyl)-β-Cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity
PublicationOne tetracyclic antidepressant, mianserin hydrochloride (MIA), has quite significant side effects on a patients’ health. Cyclodextrins, which are most commonly used to reduce the undesirable features of contained drugs within their hydrophobic interior, also have the potential to alter the toxic behavior of the drug. The present paper contains investigations and the characteristics of interaction mechanisms for MIA and the heptakis...
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MICROSEISMIC EVENT DETECTION USING DIFFERENT ALGORITHMS ON REAL DATA FROM PATCH ARRAY GEOPHONE GRID FROM EASTERN POMERANIA FRACTURING JOB
PublicationThe microseismic monitoring is a method of monitoring of fracture propagation during hydraulic fracturing process. Hydraulic fracturing is a method of reservoir stimulation used especially for unconventional gas recovery. A matrix of several thousand geophones is placed on the surface of earth to record every little tremor of ground induced by fracturing process. Afterwards, the signal is analysed and the place of tremor occurrence...
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Impact of high-pressure processing on the bioactive compounds of milk - A comprehensive review
PublicationHigh-pressure processing (HPP) is a promising alternative to thermal pasteurization. Recent studies highlighted the effectivity of HPP (400–600 MPa and exposure times of 1–5 min) in reducing pathogenic microflora for up to 5 logs. Analysis of modern scientific sources has shown that pressure affects the main components of milk including fat globules, lactose, casein micelles. The behavior of whey proteins under HPP is very important...
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Particle shape dependence in 2D granular media
PublicationParticle shape is a key to the space-filling and strength properties of granular matter. We consider a shape parameter eta describing the degree of distortion from a perfectly spherical shape. Encompassing most specific shape characteristics such as elongation, angularity and non-convexity, eta is a low-order but generic parameter that we used in a numerical benchmark test for a systematic investigation of shape dependence in sheared...
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The Effect of Hyperbaric Storage on the Nutritional Value and Retention of Certain Bioactive Proteins in Human Milk
PublicationHuman milk (HM) contains the essential macronutrients and bioactive compounds necessary for the normal growth and development of newborns. The milk collected by human milk banks is stored frozen and pasteurized, reducing its nutritional and biological value. The purpose of this study was to determine the effect of hyperbaric storage at subzero temperatures (HS-ST) on the macronutrients and bioactive proteins in HM. As control samples,...
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Iwona Kochańska dr hab. inż.
PeopleIwona Kochańska is a graduate of Faculty of Electronics, Telecommunications and Informatics, Gdansk University of Technology. She received M.Sc. degree in Automation Control and Robotics, specializing in the mobile objects control. In 2012 she received Ph.D. degree in hydroacoustics. In the same year she started working as an assistant professor in the Department of Marine Electronic Systems. The main area of interest is hydroacoustis, ...
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Visualizing Carotid Bodies With Doppler Ultrasound Versus CT Angiography: Preliminary Study
PublicationOBJECTIVE. The purpose of this article is to evaluate the utility of ultrasound in identifying carotid bodies (CBs) in patients with drug-resistant arterial hypertension. SUBJECTS AND METHODS. We enrolled 13 patients with drug-resistant hypertension into a trial for surgical CB excision. CT angiography (CTA) and Doppler ultrasound (DUS) of the cervical arteries were performed before surgery. CBs were identified in a blind manner...
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Anna Baranowska dr
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A novel method of Mycobacterium tuberculosis complex strain differentiation using polymorphic GC-rich gene sequences.
PublicationTuberculosis is one of the leading infectious diseases. In this work, a new genotyping method of Mycobacterium tuberculosis (Mtb) complex strain is presented. 27 Mtb genomes were analyzed for the presence of length polymorphism within polymorphic GC-rich gene sequences. Four genes, Rv3345c, Rv3507, Rv0747 and Rv3511, showing variation in length depending on the Mtb strain were selected for designing primer sequences flanking variable...
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The influence of 4,4'-bis(6-hydroxyhexoxy)biphenyl moieties on properties of polyurethanes based on 4,4'-methylenebis(cyclohexyl isocyanate)
PublicationZsyntetyzowano dwie serie poliuretanów z 4,4'-bis(6-hydroksyheksyloksy)bifenylu (BH6), poliadypinianu 1,6-heksylenu i diizocyjanianu 4,4'-dicykloheksylometanu o udziałach izomeru trans, wynoszącym odpowiednio 16 i 46%. Badano wpływ udziału wagowego (u) małocząsteczkowego diolu(BH6)w odniesieniu do sumy mas komonomerów diolowych, na właściwości uzyskanych poliuretanów metodami DSC, DTA, TGA, mikroskopii polaryzacyjnej, WAXS, DMTA...
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Preparation and Properties of Thermoplastic Polyurethane Composites Filled with Powdered Buckwheat Husks
PublicationBio-based fillers for the polymer composites are still interesting from the scientific and industrial point of view, due to their low cost and renewable nature. In this work partially green composites were obtained by the mixing of thermoplastic poly(ester-urethane) with the unmodified and modified (by acetylation) grinded buckwheat husks. Obtained biocomposites were characterized in the terms of their chemical structure (FTIR),...
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A benchmark for particle shape dependence
PublicationParticle shape is a major parameter for the space-filling and strength properties of granular materials. For a systematic investigation of shape effect, a numerical benchmark test was set up within a collaborative group using different numerical methods and particles of various shape characteristics such as elongation, angularity and nonconvexity. Extensive 2D shear simulations were performed in this framework and the shear strength...