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Antioxidants and HNE in redox homeostasis
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Peroxidative metabolism of fatty acids in the course of tick-borne encephalitis
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The cross talk between redox and endocannabinoids systems in the kidney of hypertensive rats after inhibitor FAAH - URB597 administration
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Antioxidants and HNE in the regulation of redox homeostasis
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Lipid peroxidation as a consequence of diabetes: effects of different treatment
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Lipid peroxidation in the pathogenesis of neuroborreliosis
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Modeling the photodynamic effect in 2D versus 3D cell culture under normoxic and hypoxic conditions
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Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine
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Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
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Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis
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Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
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Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA
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Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome1 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal.
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ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation
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The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
PublikacjaThe term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical,...
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Measurements of ASON/GMPLS connection control layer performance according to the ETSI methodology
PublikacjaMeasurements of performance have always been crucial for evaluation of telecommunication systems, especially for implementation of network control elements responsible for connection handling which regards to bandwidth reservation, modification and release. That problem also arises in Automatically Switched Optical Network/Generalized Multiprotocol Label Switching (ASON/GMLPS) architecture, which is considered as one of the components...
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Model of control plane of ASON/GMPLS network
PublikacjaASON (Automatic Switched Optical Network) is a concept of optical network recommended in G.8080/Y.1304 by ITU-T. Control Plane of this network could be based on GMPLS (Generalized Multi-Protocol Label Switching) protocols. This solution, an ASON control plane built on GMPLS protocols is named ASON/GMPLS. In the paper, we decompose the control plane problem and show the main concepts of ASON network. We propose a hierarchical architecture...
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Strontium-based nanosized phosphates as anticorrosive fi llers of epoxy and polyurethane coating compositions
PublikacjaAnticorrosive epoxy and polyurethane coatings were compounded using zinc-free nanosized phosphates of strontium (SP) or strontium and aluminum (SAP). For comparison, a nanosized calcium aluminum ammonium phosphate (CAP) and a microsized zinc phosphate (ZP) were tested. Results of salts spray and cyclic corrosion tests revealed better anticorrosive properties of the SAP-based coatings...
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HEAVE MOTION OF A VERTICAL CYLINDER WITH HEAVE PLATES
PublikacjaThe shape of a vertical cylinder resembles the classic form of a spar platform. Spar platforms are floating platforms that are successfully used in waters of great depths and have several advantages that mean they are readily used in the oil industry. Many of these advantages are also relevant to their application for offshore wind turbines, which is currently being considered. In the hydrodynamic analysis of spar platforms, the...
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Identification of Parameters Influencing the Accuracy of the Solution of the Nonlinear Muskingum Equation
PublikacjaTwo nonlinear versions of the Muskingum equation are considered. The difference between both equations relates to the exponent parameter. In the first version, commonly used in hydrology, this parameter is considered as free, while in the second version, it takes a value resulting from the kinematic wave theory. Consequently, the first version of the equation is dimensionally inconsistent, whereas the proposed second one is consistent. It...
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Smart Services supporting Drivers in Effective Cars Parking
PublikacjaThe paper shows how to design and implement intelligent, service oriented systems for management of free places in distributed car parks. The idea of SOA technology is widely used. It is assumed that a state of every car park is automatically determined by a special electronic infrastructure including IoT solutions. The information received from such an infrastructure is sent to the main management system, which processes it and,...
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Anti-plane waves in an elastic thin strip with surface energy
PublikacjaWe consider anti-plane motions of an elastic plate taking into account surface energy within the linear Gurtin–Murdoch surface elasticity. Two boundary-value problems are considered that describe complete shear dynamics of a plate with free faces or with free and clamped faces, respectively. These problems correspond to anti-plane dynamics of an elastic film perfectly or non-perfectly attached to a rigid substrate. Detailed analysis...
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Wpływ postrzeganego ryzyka oraz czynników wizerunkowych na zamiar zakupu marek własnych sieci handlowych
PublikacjaCelem przeprowadzonych badań była analiza wpływu wizerunku sklepu, postrzeganego ryzyka oraz wizerunku cenowego marek własnych na zamiar ich zakupu. Dokonano replikacji modelu zaproponowanego przez M.F. Diallo i w jej ramach zastosowano technikę wywiadu realizowanego za pośrednictwem Internetu (CAWI) i przeprowadzono analizy z wykorzystaniem modelu równań strukturalnych (SEM) przy pomocy oprogramowania AMOS. Stwierdzono, że zamiar...
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Model symulacyjny i badania sieci MPLS.
PublikacjaMultiprotocol Label Switching (MPLS) to obiecująca technika, umożliwiająca wsparcie jakości usług w sieciach szkieletowych opartych na protokole IP. Aby skorzystać z jej potencjalnych zalet, należy opracować skuteczne procedury i metody gwarantujące realizację jakości usług. Jednym z kluczowych zagadnień w tym obszarze badań jest kierowanie ruchem (ruting), a niezbędnym narzędziem odpowiedni program symulacyjny do modelowania zjawisk...
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A novel chemiluminescent immunoassay based on original acridinium ester labels as better solution for diagnosis of human toxoplasmosis than conventional ELISA test
PublikacjaToxoplasma gondii infection is one of the most common human zoonosis. Laboratory diagnosis of this disease is mainly based on the results of serological methods detecting specific antibodies in the patient’s sera. In this study we aimed to evaluate the performance of a chemiluminescence immunoassay (CLIA) based on the use of a novel immunochemical reagent in the form of the conjugate of original acridinium label (AL) attached to...
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Synthesis and Characterization of Poly(zwitterionic) Structures for Energy Conversion and Storage
PublikacjaZwitterions are unique class of molecules that possess two functional groups bearing electric charges, one positive and second negative. This setup results in peculiar properties such as high water retention and anti-fouling capability. Therefore, zwitterionic coatings and gels are commonly applied in e.g. biosensing and bioelectronic devices. Despite those applications, there are other perspectives for zwitterionic materials....
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Synthesis and biological activity of mycophenolic acid-amino acid derivatives
PublikacjaIn search of new immunosuppressants, mycophenolic acid (MPA) was coupled with amino acid methyl esters followed by hydrolysis to analogs bearing free carboxylic groups. The obtained compunds were tested in vitro as growth inhibitors of lymphoid cell line (Jurkat) and human peripheral blood mononuclear cells (PBMC) from healthy donors. According to obtained results recovering of free carboxylic group increased their activity. Additionally,...
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Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing
PublikacjaMouse fetuses up to 16 day of embryonic development and nude (Foxn1- deficient) mice are examples of animals that undergo regenerative (scar-free) skin healing. The expression of transcription factor Foxn1 in the epidermis of mouse fetuses begins at embryonic day 16.5 which coincides with the transition point from scar-free to scar-forming skin wound healing. In the present study, we tested the hypothesis that Foxn1 expression...
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Risk of power cables insulation failure due to the thermal effect of solar radiation
PublikacjaLow-voltage, as well as high-voltage power cable lines, are usually buried in the ground. The ampacity of the power cables in the ground mainly depends on the thermal resistivity of the soil, which may vary in a wide range. A common practice in power cable systems performance is to supply them from a pole of an overhead line. If so, a section of the line is located in free air and can be directly exposed to solar radiation. In...
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Impact of blending with polystyrene on the microstructural and electrochemical properties of SiOC ceramic
PublikacjaIn this work, we present the electrochemical behavior and microstructural analysis of silicon oxycarbide (SiOC) ceramics influenced by an addition of polystyrene (PS). Polymer-derived ceramics were obtained by pyrolysis (1000°C, Ar atmosphere) of different polysiloxanes prepared by sol–gel synthesis. This method is very effective to obtain desired composition of final ceramic. Two alkoxysilanes phenylthriethoxysilane and diphenyldimethoxysilane...
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Rough Set Based Modeling and Visualization of the Acoustic Field Around the Human Head
PublikacjaThe presented research aims at modeling acoustical wave propagation phenomena by applying rough set theory in a novel manner. In a typical listening environment sound intensity is determined by numerous factors: a distance from a sound source, signal levels and frequencies, obstacles’ locations and sizes. Contrarily, a free-field is characterized by direct, unimpeded propagation of the acoustical waves. The proposed approach is...
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Silicon Oxycarbide (SiOC) Ceramic Materials as Anodes for Lithium Ion Batteries
PublikacjaPolymer derived ceramics (PDCs) have attracted attention as alternative anode material for Li-ion batteries. It has been found that ternary SiOC and SiCN ceramics obtained through pyrolysis of various preceramic polymers display high reversible capacities of 500 – 650 mAh/g. In this work we try to correlate the electrochemical performance of polymer derived silicon oxycarbide with its chemical composition and microstructural features....
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Verification of the method of reconstructing convective velocity fields on the basis of temperature fields in vertical, differential and equally heated, open and closed channels
PublikacjaThis paper describes a method of reconstructing velocity fields, i.e. a numerical reconstruction procedure (NRP) that involves the numerical processing of experimentally measured temperature distributions in free convection heat transfer. The NRP consists in solving only the continuity and Navier–Stokes equations with an additional source term. This term is proportional to a known temperature (e.g. from a thermal imaging camera)...
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Przepustowość przepustu niezatopionego
PublikacjaPodczas przepływu w warunkach niezatopionego wlotu i wylotu w przewodzie przepustu woda tworzyć będzie swobodne zwierciadło. Przepływ bezciśnieniowy w przewodzie przepustu może wystąpić również w warunkach zatopionego wlotu. W pracy porównano wyniki obliczeń przepustowości całego przepustu i samego przewodu o przekroju kołowym i kwadratowym. W warunkach spokojnego ruchu wody, przy braku spiętrzenia na wylocie, o przepustowości...
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Non-destructive inspection of ground anchors using guided wave propagation
PublikacjaThis paper deals with numerical and experimental investigations of specific problems of guided wave propagation in ground anchors. The research focuses on recognizing the phenomenon of the energy transfer between anchor components. Particular attention is paid to characteristic features of guided waves propagating in free and embedded parts of the tendon, at the interface between the tendon and the surrounding anchor body as well...
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Call Control Evaluation in ASON/GMPLS Architecture
PublikacjaThe Automatically Switched Optical Network (ASON) utilizing Generalized Multi–Protocol Label Switching (GMPLS) protocols named as ASON/GMPLS is one of the propositions of Next Generation Network. The basic assumption of ASON control plane is a separation of call control from connection control. The control plane is divided into call control and connection control components. Presented work regards the problem of call control evaluation...
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How Swiss Watchmaking Brands are Communicating Made in Switzerland
PublikacjaCountry-of-origin indications, also called “made in” labeling [35], are utilized in marketing strategies by companies to distinguish themselves from others, trying to associate their products with positive characteristics [9]. Swiss watchmaking companies have an iconic status that is essential to their reputation - mainly due to their high quality, precision, innovation, and craftsmanship [7]. They are also using country-of-origin...
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The realization of ASON/GMPLS control plane
PublikacjaASON (Automatic Switched Optical Network) is a concept of optical network recommended in G.8080/Y.1304 by ITU-T. Control Plane of this network could be based on GMPLS (Generalized Multi-Protocol Label Switching) protocols like RSVP-TE, OSPF-TE, LMP. This solution is named ASON/GMPLS. In this chapter we present the control plane problems and proposes ASON/GMPLS network realization that are tested on testbed consists of three and...
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Outlet Flow Velocity In Circular Culvert
PublikacjaThe outlet flow velocity in the end section of the culvert barrel depends in most cases on the culvert geometry, including the barrel slope, as well as on upstream and downstream channel parameters. Flowing water can create pressure flow or free surface flow in the culvert barrel. In the case of an unsubmerged barrel outlet, the free-surface flow is more frequent than the full flow. Increased velocities can cause channel bed scour...
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Photovoltaic phenomena in devices with perfluorozincphthalocyanine layer
PublikacjaThe course of photovoltaic phenomenon in organic photovoltaic cells utilizing thin layers of perfluorozincphthalocyanine was studied in few single and planar bilayer configurations. Mechanisms of photogeneration and recombination of free charge carriers were determined and active interfaces were localized. In case of single layer cells these interfaces were located at the front electrode/F16ZnPc junctions, whereas photogeneration...
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Propagation of Acoustic Disturbances in Shallow Sea
PublikacjaPropagation of acoustic waves in shallow sea differs fundamentally from the same phenomenon occurring in deep sea in view of non-negligible distance from the sea bottom in the first case, where presence of two regions limiting the water layer results in the acoustic pressure distribution induced by a harmonic source has an interferential nature as a result of multi-path propagation of the acoustic signal. These interferential properties...
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The structure of demand and its economic consequences for urban transport
PublikacjaThe structure of demand for urban transport services, determined by the share of passengers entitled to free and reduced fares, is an important factor influencing its economic condition. The aim of this article is to present the results of research into the structure of demand for urban transport as well as its economic consequences. The article begins by considering the nature of the determinants and consequences of the public...
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Dynamics of Antimicrobial Peptide Encapsulation in Carbon Nanotubes: The Role of Hydroxylation
PublikacjaIntroduction: Carbon nanotubes (CNTs) have been widely employed as biomolecule carriers, but there is a need for further functionalization to broaden their therapeutic application in aqueous environments. A few reports have unraveled biomolecule–CNT interactions as a measure of response of the nanocarrier to drug-encapsulation dynamics. Methods: Herein, the dynamics of encapsulation of the antimicrobial peptide HA-FD-13 (accession...
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HOW EFFICIENT IS NOISE LABELING OF TIRES?
PublikacjaSince 2012 all new tires in Europe must be labeled. The label contains general information about tire performance concerning rolling resistance (that corresponds to fuel economy), noise emission and wet grip (only for passenger car tires). Measurements of noise performance of tires must be performed according to the Annex 3 of the Regulation No 117 of the Economic Commission for Europe of the United Nations. The regulation specifies...
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Traffic Model of IMS/NGN Architecture with Transport Stratum Based on MPLS Technology
PublikacjaGrowing expectations for a fast access to information create strong demands for a universal telecommunication network architecture, which provides various services with strictly determined quality. Currently it is assumed that these requirements will be satisfied by Next Generation Network (NGN), which consists of two stratums and includes IP Multimedia Subsystem (IMS) elements. To guarantee Quality of Service (QoS) all NGN stratums...
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Analytical Traffic Model for a Multidomain IMS/NGN Network Including Service and Transport Stratum
PublikacjaThis paper addresses the problem of modelling call processing performance (CPP) in a multidomain Next Generation Network (NGN) architecture including the elements of the IP Multimedia Subsystem (IMS) in service stratum and based on the Multiprotocol Label Switching (MPLS) technology in transport stratum. An analytical traffic model for such an architecture is proposed by integrating the formerly implemented submodels of service...
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Differentiation Between Spirits According to Their Botanical Origin
PublikacjaAgricultural distillates are used for the production of spirit beverages. As more and more products with a specific botanical composition specified on the label are produced (e.g. rye vodkas, wheat vodkas and Polish Vodka, which cannot be produced with the addition of maize distillate), it is necessary to look for quicker and more accurate methods allowing the determination of botanical origin of alcoholic beverages and materials...
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Low-Coherence Interferometric Fiber-Optic Sensors with Potential Applications as Biosensors
PublikacjaFiber-optic Fabry-Pérot interferometers (FPI) can be applied as optical sensors, and excellent measurement sensitivity can be obtained by fine-tuning the interferometer design. In this work, we evaluate the ability of selected dielectric thin films to optimize the reflectivity of the Fabry-Pérot cavity. The spectral reflectance and transmittance of dielectric films made of titanium dioxide (TiO2) and aluminum oxide (Al2O3) with...
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Enhanced susceptibility of SARS-CoV-2 spike RBD protein assay targeted by cellular receptors ACE2 and CD147: Multivariate data analysis of multisine impedimetric response
PublikacjaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enters the cells through the binding of spike protein to the host cell surface-expressing angiotensin-converting enzyme 2 (ACE2) or by endocytosis mediated by extracellular matrix metalloproteinase inducer (CD147). We present extended statistical studies of the multisine dynamic electrochemical impedance spectroscopy (DEIS) revealing interactions between Spike RBD and...
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Low-Coherence Interferometric Fiber-Optic Sensors with Potential Applications as Biosensors
PublikacjaFiber-optic Fabry-Pérot interferometers (FPI) can be applied as optical sensors, and excellent measurement sensitivity can be obtained by fine-tuning the interferometer design. In this work, we evaluate the ability of selected dielectric thin films to optimize the reflectivity of the Fabry-Pérot cavity. The spectral reflectance and transmittance of dielectric films made of titanium dioxide (TiO2) and aluminum oxide (Al2O3) with...