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Mn-Co spinel coatings on Crofer 22 APU by electrophoretic deposition: Up scaling, performance in SOFC stack at 850 °C and compositional modifications
PublikacjaCeramic coatings for metallic interconnects play a key role in limiting corrosion and chromium evaporation in solid oxide cells. This study presents the upscaling of the electrophoretic deposition (EPD) technique to process Mn-Co spinels on real-dimension Crofer 22 APU interconnects and the test in a SOFC stack. Area specific resistance of long-term test conducted for 5000 h at 850 °C demonstrated that two-steps sintering has a...
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Towards a classification of networks with asymmetric inputs
PublikacjaCoupled cell systems associated with a coupled cell network are determined by (smooth) vector fields that are consistent with the network structure. Here, we follow the formalisms of Stewart et al (2003 SIAM J. Appl. Dyn. Syst. 2, 609–646), Golubitsky et al (2005 SIAM J. Appl. Dyn. Syst. 4, 78–100) and Field (2004 Dyn. Syst. 19, 217–243). It is known that two non-isomorphic n-cell coupled networks can determine the same sets of...
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Reaktory elektrochemiczne w przemyśle - konstrukcja i zastosowania
PublikacjaZ biegiem lat reakcje elektrochemiczne przestały być postrzegane jedynie jako eksperymenty laboratoryjne lub proste baterie. Chociaż mechanizm reakcji i budowa prostych reaktorów znana jest ludzkości już od ponad 100 lat w ostatnich latach można zauważyć największy wzrost zainteresowania tą dziedziną. Nowy stale opracowywane są lepsze projekty budowy reaktorów. Modyfikacje to nie tylko rodzaje i formy materiałów, z których wykonane...
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Utilization of molten salt synthesis route in ceramics production
PublikacjaThe molten salt synthesis method is widely used to prepare ceramic powders for various applications e.g. piezoelectric devices or electrolytes for solid oxide fuel cells. The usage of this method workdwide is quite common especially in piezoelectric powder synthesis. In this work several application of the method is presented and the advantages of this route are numbered.
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Renewable Resources for Polyurethanes and Polyurethane Composites: A Review
PublikacjaEach year, more than two million tons of polyurethane is produced in the EU by reacting isocyanates with polyols made from fossil fuel. In addition, there are appreciable quantities of petroleum based functional additives applied in the industry nowadays for both polyols and polyurethane materials. It is therefore of key importance to develop sustainable economically viable polyols with enhanced functionalities, and thereby reducing...
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Replicating DNA by cell factories: roles of central carbon metabolism and transcription in the control of DNA replication in microbes, and implications for understanding this process in human cells
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Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data
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Author Correction: Decreased integrity of exercise-induced plasma cell free nuclear DNA – negative association with the increased oxidants production by circulating phagocytes
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Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines
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Successful Treatment of Persistent SARS-CoV-2 Infection in a B-Cell Depleted Patient with Activated Cytotoxic T and NK Cells: A Case Report
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Badania rozkładu temperatury na powierzchni oświetlonego i obciążonego modułu fotowoltaicznego = Temperature distribution on the surface of illuminated and loaded solar cell module
PublikacjaTemperatura powierzchni modułu fotowoltaicznego, która stanowi powierzchnię absorbującą promieniowanie słoneczne, wzrasta w efekcie: absorpcji promieniowania słonecznego (nie-aktywnej absorpcji fotonów, która nie prowadzi do generowania par nośników ładunku), rekombinacji par elektron-dziura, przepływu fotoprądu (ciepło Joule'a - Lenza generowane jest w efekcie przepływu prądu przez rezystancję szeregową złącza p-n). Kolektor słoneczny...
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Role of rituximab in the first-line therapy of high-risk diffuse large B-cell lymphoma: a retrospective analysis by the Polish Lymphoma Research Group
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Improved cytotoxicity and preserved level of cell death induced in colon cancer cells by doxorubicin after its conjugation with iron-oxide magnetic nanoparticles
PublikacjaA promising strategy for overcoming the problem of limited efficacy in antitumor drug delivery and in drug release is the use of a nanoparticle-conjugated drug. Doxorubicin (Dox) anticancer chemotherapeutics has been widely studied in this respect, because of severe cardiotoxic side effects. Here, we investigated the cytotoxic effects, the uptake process, the changes in cell cycle progression and the cell death processes in the...
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Cancer stem cells in drug resistance and drug screening: can we exploit the cancer stem cell paradigm in search for new antitumor agents?
PublikacjaPraca przedstawia przegląd literatury dotyczącej hipotezy komórek pierwotnych nowotworu, w szczególności w ich oporności na istniejące terapie. Dyskutowane jest także zagadnienie możliwości wykorzystania wiedzy o tych komórkach do konstrukcji nowych testów do badań przesiewowych in vitro w celu poszukiwania nowych leków przeciwnowotworowych.
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Two small RNAs conserved in Enterobacteriaceae provide intrinsic resistance to antibiotics targeting the cell wall biosynthesis enzyme glucosamine-6-phosphate synthase
PublikacjaFormation of glucosamine-6-phosphate GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, GlmZ is bound by adapter protein RapZ and recruited to cleavage by RNase E inactivating the sRNA. The homologous sRNA GlmY activates...
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Risks related to car fire on innovative Poroelastic Road Surfaces-PERS
PublikacjaTo reduce tyre/road noise, the concept of poroelastic road surfaces (PERS) was invented. PERS is a road surface material that is porous, and at the same time, it is flexible because of the substantial amount of rubber granulate content (from 20% to 85%). The rubber and stone particles are bound by polyurethane resin instead of bitumen. It was feared that in case of fire, because of the high content of rubber and polyurethane, there...
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Optimal shape design of multi-element trawl-doors using local surrogate models
PublikacjaTrawl-doors have a large influence on the fuel consumption of fishing vessels. Design and optimiza-tion of trawl-doors using computational models are a key factor in minimizing the fuel consump-tion. This paper presents an optimization algorithm for the shape design of trawl-door shapes using computational fluid dynamic (CFD) models. Accurate CFD models are computationally expensive. Therefore, the direct use of traditional optimization...
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THE IDENTIFICATION OF TOXIC COMPOUND EMISSION SENSITIVITY AS A DIAGNOSTIC PARAMETER DURING DYNAMIC PROCESSES OF THE MARINE ENGINE
PublikacjaChanging some parameters of the engine structure alters the emission of harmful components in the exhaust gas. This applies in particular to the damage of charge exchange system as well as fuel system and engine supercharger. These changes are much greater during the dynamic states and their accompanying transitional processes. The different sensitivity of diagnostic parameters to the same force, coming from the engine structure,...
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Fuctional structure of diagnostic system for wheeled tractors
PublikacjaAn application of computer controlled fuel injection systems in vehicle engines and growing demands concerning toxic substances emission and fuel consumption was a main reason for OBD (On Board Diagnosis) development. In spite of a great technological development, only some tractors are equipped in diagnostic systems. On board diagnosis is strongly connected with emission demands and does not concern other important vehicle functions.In...
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Microstructural Design of Ba0.5La0.5Co0.5Fe0.5O3 Perovskite Ceramics
PublikacjaBa0.5La0.5Co0.5Fe0.5O3 was synthesized in the solid-state reaction route. The influence of ball milling parameters (such as milling media size, angular velocity, and time), pelletizing pressure, and annealing parameters on the microstructure was studied. The grain size distribution and density or specific surface area changes were investigated in each approach while the individual parameters were changed. The evaluation of BLCF...
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Impact of strontium non-stoichiometry of SrxTi0.3Fe0.7O3-δ on structural, electrical, and electrochemical properties for potential oxygen electrode of intermediate temperature solid oxide cells
PublikacjaThis work presents the results of a comprehensive study on the impact of the A-site non-stoichiometry of SrxTi0.3Fe0.7O3-δ (x = 0.90, 0.95, 1.00, 1.05) ceramics on their physicochemical properties. The materials were fabricated by the conventional solid-state reaction method and their structure was determined by X-ray diffractometry, X-ray photoelectron spectroscopy and electron microscopy. Their sintering and thermal expansion...
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Ionic conductivity behavior by activated hopping conductivity (AHC) of barium aluminoborosilicate glass–ceramic system designed for SOFC sealing
PublikacjaNon-conducting BaO-B2O3-Al2O3-SiO2 parent glasses designed for solid oxide fuel cell (SOFC) sealing applications were prepared using the melt-quenching technique. The glass formation region was determined according to phase equilibrium relations and was found to be in the composition range 70BaO-(x)Al2O3-(10−x)B2O3-20SiO2 where 3.0 < x < 6.0 wt%. The conductivity values obtained conductivity ranged from 10−5 to 10−10 S/cm at temperatures...
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MnCo2O4 deposited by spray pyrolysis as a protective layer for stainless steel interconects
PublikacjaStainless steel interconnects working in Solid Oxide Fuel Cells stacks are exposed to high temperature resulting in their corrosion. Protective layers for the hydrogen and oxygen sides are necessary to protect the interconnect material, prolongate the stack lifetime and maintain the output power. In this paper MnCo2O4 protective layer for the oxygen side of the interconnect is deposited by spray pyrolysis and is examined.
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The effectivness of fault detection in common rail injectors examination methods
PublikacjaThe article presents the effectiveness tests of fault detection in common rail injectors. 40 injectors with different wear levels were tested. Testing was made on two test benches of a completely different design. Research includes comparison of accuracy, reproducibility and testability to detect specific defects. A device was created for visualization of the fuel injector spraying steam.
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High gain/bandwidth off‑chip antenna loaded with metamaterial unit‑cell impedance matching circuit for sub‑terahertz near‑field electronic systems
PublikacjaAn innovative off-chip antenna (OCA) is presented that exhibits high gain and efficiency performance at the terahertz (THz) band and has a wide operational bandwidth. The proposed OCA is implemented on stacked silicon layers and consists of an open circuit meandering line. It is shown that by loading the antenna with an array of subwavelength circular dielectric slots and terminating it with a metamaterial unit cell, its impedance...
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Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
PublikacjaIn 2009 Candida auris was first isolated as fungal pathogen of human disease from ear canal of a patient in Japan. In less than a decade, this pathogen has rapidly spread around the world and has now become a major health challenge that is of particular concern because many strains are resistant to multiple class of antifungal drugs. The lack of available antifungals and rapid increase of this fungal pathogen provides an incentive...
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Analysis of carboxylic acid metabolites from the tricarboxylic acid cycle in Bacillus subtilis cell extract by capillary electrophoresis using an indirect photometric detection method
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Favourable outcomes in patients with early-stage non-small-cell lung cancer operated on by video-assisted thoracoscopic surgery: a propensity score-matched analysis†
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Destabilization of β‐Hemocyanin from Helix pomatia in Presence of Choline Amino Acids Results in Improved Cell Specificity and Cytotoxicity against Human Breast Cancer
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Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit
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Genes Involved in the Processes of Cell Proliferation, Migration, Adhesion, and Tissue Development as New Potential Markers of Porcine Granulosa Cellular Processes In Vitro: A Microarray Approach
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High-dose chemotherapy with autologous stem cell transplantation is an effective treatment of primary refractory Hodgkin's disease. Retrospective study of the Polish Lymphoma Research Group
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Radioimmunotherapy with 90Y-ibritumomab tiuxetan is a safe and efficient treatment for patients with B-cell lymphoma relapsed after auto-SCT: an analysis of the international RIT-Network
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Down-regulation of DNA topoisomerase IIalpha leads to prolonged cell cycle transit in G2 and early M phases and increased survival to microtubule-interacting agents
PublikacjaInhibitory polimeryzacji mikrotubul wykazują preferencyjną toksyczność wobec komórek mitotycznych. W ramach tego projektu badaliśmy czy oporność komórek ludzkich białaczek na inhibitor mikrotubul, winkrystynę, prowadzi do zmian w regulacji progresji cyklu komórkowego. Nasze wyniki wskazują, że oporności na winkrystynę towarzyszą zmiany w długości fazy G2 i M w nieobecności i obecności inhibitora wrzeciona mitotycznego, nokodazolu....
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O07 Filaggrin insufficiency renders keratinocyte-derived small extracellular vesicles capable of affecting CD1a-mediated T-cell responses and promoting allergic inflammation
PublikacjaThe association between FLG loss-of-function mutations and the development of atopic dermatitis (AD) indicates that filaggrin is critical to skin barrier function; the mutations are also linked to additional allergic manifestations, but it is unknown how the skin may influence inflammation in distant tissues. Here we investigated the impact of filaggrin insufficiency on keratinocyte-derived exosome-enriched small extracellular...
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Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.
PublikacjaBackground Among the studied antitumor acridinone derivatives developed in our laboratory, 5-dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) and 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) exhibited cytotoxic and antitumor properties against several cancer types and were selected to be evaluated in preclinical and early-phase clinical trials. In the present work, we investigated the impact of C-1305...
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Versatile method employing basic techniques of genetic engineering to study the ability of low molecular weight compounds to bind covalently with DNA in cell free systems.
PublikacjaMechanizm działania większości leków przeciwnowotworowych oraz związków rakotwórczych polega na ich kowalencyjnym wiązaniu z DNA. Poziom tego wiązania jest zazwyczaj bardzo niski, co powoduje, że potrzebne są niezwykle czułe metody aby kowalencyjna modyfikacja mogła być w ogóle wykryta. My podjęliśmy próbę zastosowania w tym celu prostych, szybkich i sprawdzonych technik inżynierii genetycznej: metody PCR do uzyskania fragmentu...
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Environmental Risk Assessment of WWII Shipwreck pollution
PublikacjaThe pollution of the sea is a global problem that has arisen as a consequence of the industrialization of the world and the intense transportation of crude oil and the products of its refinement. As sailing vessels were replaced by motor propelled ships towards the end of the 19th century, a new source of sea water pollution came into being. Every emergency involving a tanker carrying crude oil and its products is a potential source...
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Improving operating efficiency of a gas turboset via cooperation with an absorption refrigerating machine
PublikacjaThe analysis of increase of ambient air temperature entering the compressor on reduction in power output from the turbine and increase fuel use was conduced. For medium size gas turbine operates in winter and summer conditions elementary power and economical values was calculated. Conditions of the determination of turbine inlet air cooling solution (using thermal storage for reduce equipment size) are presented
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Hydrogen induced degradation of structural steel exposed to the technical liquid hydrocarbons
PublikacjaSusceptibility of the differently heat treated 26H2MF steel to stress corrosion cracking has been evaluated in the constant strain rate tension tests done at the strain rate 10-6s-1 and in the constant load tests done at the 0,98 of fracture load. The boiler fuel and the aged mineral oil at 135C and 80C respectively, have been used as the aggressive environments.
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Selected Problems of Cogeneration Energy Systems Designing, Fueled with Landfill Biogas
PublikacjaThe article discusses the impact of the quality of biogas fuel for operation of generating sets with internal combustion engines. There are presented selected investigation results of landfill biogas fueled gensets operation. The article includes also discussion of the possibility of increasing the efficiency of biogas fuelled cogeneration systems. It also presents guidelines for the optimal design of landfill biogas fueled engines,...
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Research on flue gas flow measurement and modelling in the moving grate biomass boiler
PublikacjaThe aim of this research was to determine the nature of gas flow in a grate boiler model by the method of Particle Image Velocimetry (PIV) and CFD. The paper presents the comparison of the PIV results with numerical simulations made in the environment of ANSYS Fluent. The main goal of the experiment was to describe the phenomena occurring on the grate. Methodology of modelling solid fuel combustion on the moving grate was proposed...
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Technological solutions for boosting hydrogen role in decarbonization strategies and net-zero goals of world shipping: Challenges and perspectives
PublikacjaFacing the problems concerning greenhouse gas (GHG) emissions from international ocean shipping has meant that the latest regulations of the International Maritime Organization, issued on 1st January 2023, have come into force, with the aim of reducing GHG emissions from maritime activities. Hydrogen has been suggested as an alternative fuel to achieve decarbonization ambitions in the near future. Although hydrogen has been investigated...
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Advanced nanomaterials and metal-organic frameworks for catalytic bio-diesel production from microalgal lipids – A review
PublikacjaIncreasing energy demands require exploring renewable, eco-friendly (green), and cost-effective energy resources. Among various sources of biodiesel, microalgal lipids are an excellent resource, owing to their high abundance in microalgal biomass. Transesterification catalyzed by advanced materials, especially nanomaterials and metal-organic frameworks (MOFs), is a revolutionary process for overcoming the energy crisis. This review...
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An Optimized Ka-Band Low Profile Dual-Polarized Transmitarray Antenna With 2D Beam Switching
PublikacjaThis article presents an optimized dual-polarized transmitarray antenna (TA) designed for MIMO applications at the Ka-band, capable of switching beams in two directions. The antenna aperture uses a small unit cell with three layers of Taconic RF-35 dielectric substrates, which can be easily fabricated using PCB technology. The unit cell achieved a 360-degree phase shift and a transmission magnitude exceeding –0.4 dB at 28 GHz....
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Possibilities of the performance improvement of the aero- and marine propulsion units equipped with combustion piston engines
PublikacjaWithin the paper there have been presented the authors' opinions concerning possibilities and needs of the performance optimization of the aero- and marine units powered by piston engines both of ''classic'' and contemporary construction. There have been also discussed the reserves contained within combustion piston engines which enable its performance improvement (the power and specific fuel consumption) as well as the fulfillment...
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Impact of low-temperature sintering on the Fe-based amorphous coatings
PublikacjaBulk metallic glasses (BMGs) have gained a lot of attention in recent years due to their outstanding properties such as high hardness and excellent wear and corrosion resistance. However, they are restricted in industrial applications due to their extreme brittleness. Iron based amorphous coatings from BMGs are the best solution to use them by overcoming the problem of extreme brittleness. The coatings can be sprayed by various...
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Market Price Prediction of Property Rights from Gas Fired Plants or Plants with Total Installed CHP Source Capacity Below 1 MW until 2025
PublikacjaThe resolution on the Polish Energy Policy until 2030 (PEP-30) was adopted by the Council of Ministers on 10 November 2009. The document specifies the combined electricity and heat generation as a direction of pursuing the goals of energy efficiency, fuel and energy supply security, competitive fuel and energy markets development, and reduction of the energy sector’s environmental impact. PEP-30 assumes that electricity generation...
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Hydrogen production from ethanol In nitrogen microwave plasma At atmospheric pressure
PublikacjaHydrogen seems to be one of the most promising alternative energy sources. It is a renewable fuel as it could be produced from e.g. waste or bio-ethanol. Furthermore hydrogen is compatible with fuel cells and is environmentally clean. In contrast to conventional methods of hydrogen production such as water electrolysis or coal gasification we propose a method based on atmospheric pressure microwave plasma. In this paper we present...
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High-efficient, zero-emission energy production
PublikacjaThis paper presents innovative thermodynamiccycles with high-efficient, zero-emission energy production. The main aim of this work is to show the role of nano-phenomena in the enhancement of the power of thermodynamic cycles. For that purpose, the cycles using oxy-combustion and spray ejected condensation are first studied and, secondly hybrid cycles using fuel cells and gas turbines are presented. The role of nano-phenomena in...