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Wyniki wyszukiwania dla: heat shock proteins
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Prediction of protein structure with the coarse-grained UNRES force field assisted by small X-ray scattering data and knowledge-based information
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Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
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Atomic resolution crystal structure of HV-BBI protease inhibitor from amphibian skin in complex with bovine trypsin
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Impact of AlphaFold on structure prediction of protein complexes: The CASP15‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 54, the 5th joint CASP-CAPRI protein assembly prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo-trimers, 13 heterodimers including 3 antibody–antigen complexes, and 7 large assemblies. On average 70 CASP and CAPRI predictor groups, including more than 20 automatics servers, submitted models for each target. A total of 21 941 models submitted by these groups...
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Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment
PublikacjaWe present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly...
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Energy Security of Polish Consumers in 2004-2021
Dane BadawczeEnergy security is one of the most important components of economic security. It is influenced not only by access to energy sources and the economic situation of the state and the individual consumer. In the years 2004–2021, energy security of the individual consumer in the economic dimension significantly improved. This was due to several factors:1....
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen AMA1-MIC1-MIC3
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC3-MAG1-ROP1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC1-MIC3-ROP1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen MIC3-MAG1-AMA1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Construction, production and evaluation of the diagnostic utility of a recombinant Toxoplasma gondii chimeric antigen AMA1-MIC1-ROP1
Dane BadawczeThe intracellular parasite Toxoplasma gondii has the ability to infect a wide range of warm-blooded animals, including humans. Currently, diagnosis of toxoplasmosis is based mainly on the use of the native antigens in enzyme immunoassay which allow for detection of IgG, IgM and IgA antibody classes. However, in some cases the performed studies give...
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Charakterystyka eksploatacyjna pomp ciepła zainstalowanych w oczyszczalni ścieków
PublikacjaW artykule przedstawiono charakterystykę eksploatacyjną sprężarkowych pomp ciepła zainstalowanych w oczyszczalni komunalnej i wykorzystujących ścieki oczyszczone jako dolne źródło ciepła. Zastosowanie ścieków oczyszczonych jest uzasadnione ich dostępnością oraz stosunkowo wysoką temperaturą (10-25°C). Prawidłowa eksploatacja układu wymaga zastosowania pośredniego obiegu parowacza oraz regularnych zabiegów czyszczenia wymiennika...
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New recombinant chimeric antigens, P35-MAG1, MIC1-ROP1, and MAG1-ROP1, for the serodiagnosis of human toxoplasmosis
PublikacjaThe aim of the study was to evaluate the usefulness of 3 chimeric Toxoplasma gondii antigens, P35-MAG1,MIC1-ROP1 andMAG1-ROP1, in the serodiagnosis of an acute toxoplasmosis in humans. Proteins were produced as fusion proteins containing His tags ends and then further purified by metal affinity chromatography. Their application for the diagnosis of recently acquired T. gondii infection was tested in IgG and IgM enzyme-linked immunosorbent...
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Novel primosomal protein B from thermophilic bacterium Thermoanerobacter tengcongensis
PublikacjaWe report the identification and characterization of theprimosomal protein B (PriB) from thermophilic bacteriumThermoanerobacter tengcongensis (TtePriB). It is the largestknown bacterial PriB protein consisting 216 amino acidresidues with a calculated molecular mass of 25 kDa. Surprisingly,it is functional as monomer containing two single-stranded DNA binding domain (OB-fold) and it is thecompletely new kind structure of SSB protein....
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Development of chromatographic and mass spectrometry conditions for untargeted lipidomic analysis of human breast milk
PublikacjaHuman breast milk (HBM) is a complex biofluid containing components which are essential for the proper growth of the newborn (for example nutrients such as carbohydrates, proteins, lipids) and also bioactive substances. According to the literature, most of studies involving HBM nutrients investigations focused essentially on the determination of proteins. The molecular composition of lipids in HBM is not well known as the protein...
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Transient States during Short-circuit in a Line Powered by UPS and its Impact on Earth Fault Loop Impedance Measurement and Power Quality
PublikacjaThe short-circuit in a line powered by Uninterruptible Power Supply (UPS) during different UPS operation modes is presented in the article. The transient state condition related to the short-circuit in a line fed from double conversion On-line UPS is discussed in detail. The results of the measurements of earth fault loop impedance (FLI) in circuits powered by UPS with the instruments of various manufacturers are presented. The...
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TG-hydroxyl groups in TiO2-P25
Dane BadawczeTG analyses were performed for powdered TiO2 - commercial P25 sample, which was heat-treated from room temperature to 500 C in the nitrogen atmosphere. Mass loss at lower temperature such as 120 C was related to the physisorbed water, and that one occurring at 500 C to the chemisorbed hydroxyl groups.
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INTENSYFIKACJA WYMIANY CIEPŁA W WYMIENNIKU WĘŻOWNICOWYM Z WYKORZYSTANIEM PRZEGRÓD O RÓŻNEJ GEOMETRII
PublikacjaW pracy zaprezentowano możliwości wykorzystania pasywnej intensyfikacji wymiany ciepła w postaci przegród dla podniesienia efektywności energetycznej wymiennika wężownicowego. Badania zostały przeprowadzone z wykorzystaniem modułowego wymiennika z wężownicą w postaci grzałki elektrycznej. Medium odbierającym ciepło była woda o stałych parametrach cieplnoprzepływowych na wlocie do modułu. Pomiary przeprowadzono dla szerokiego zakresu...
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Nanostructure and dielectric behavior of vanadate glasses containing BaTiO3
PublikacjaThe ac and dc electrical conductivity of barium titanate doped bismuth-vanadate as-quenched and heat-treated materials was measured in the frequency range from 1 mHz to 1 MHz and in the temperature range from 153 K to 423 K with the impedance spectroscopy method. The microstructure was investigated by means of XRD, scanning electron microscopy (SEM), atomic force microscopy (AFM) and confocal microscopy. The obtained results showed...
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SEM/EDX data of (Cr,Fe,Mn,Co,Ni)3O4 High-entropy spinel oxide thin films deposited on amorphous SiO2 substrate by spray pyrolysis techniqe
Dane BadawczeThis Data set include SEM and EDX results of (Mn,Co,Fe,Ni,Cr)3O4 high-entropy spinel oxide prepared in the form of a ~ 500 nm thin film utilising a facile spray pyrolysis technique. The structural and electrical properties of the layers were characterised after exposure to temperatures in the range of 400–900 ◦C. The as-deposited layers were amorphous,...
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TEM data of (Cr,Fe,Mn,Co,Ni)3O4 High-entropy spinel oxide thin films deposited on amorphous SiO2 substrate by spray pyrolysis techniqe
Dane BadawczeThis Dataset include presentation of summarized TEM investigation of (Mn,Co,Fe,Ni,Cr)3O4 high-entropy spinel oxide prepared in the form of a ~ 500 nm thin film utilising a facile spray pyrolysis technique. The structural and electrical properties of the layers were characterised after exposure to temperatures in the range of 400–900 ◦C. The as-deposited...
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Functional properties of edible films for food applications - a review
PublikacjaApplication of natural polymers to forming edible films for food applications has been reviewed. Due to the hydrophilic nature of proteins and polysaccharides, films prepared from these polymers are too susceptible to moisture. Modification of them with critically selected a suitable compounds can result in their improved functional properties and making them useful for food packaging.
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EXPERIMENTAL INVESTIGATION OF FREE CONVECTION OF GLYCOL-Al2O3 NANOFLUID FROM HORIZONTAL TUBE
PublikacjaNanofluids came to be seen as a new generation of coolants, both in single- and two phase systems. Furthermore, nanofluids or nanocomposites may be used as a media in a thermal energy storage (TES) in such systems as sensible heat storage (SHS) and phase change materials (PCM). In the SHS systems the dominating mechanism of the heat transfer is natural convection. However, in the literature only a few investigations of free convection...
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Experimental investigation of forced convection of water-Al2O3 nanofluids inside horizontal tubes,
PublikacjaIn this paper, forced convection of water–Al2O3 nanofluids inside horizontal copper tube is studied experimentally. Experiments were conducted for three, i.e. 0.1%, 1% and 5% nanoparticle mass concentrations under transition and turbulent flow regimes. Average heat transfer coefficients and pressure drop values were determined and compared to distilled water. Enhancement of heat transfer for lower nanoparticle concentration and...
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Experimental investigation of free convection of glycol-Al2O3 nanofluid from horizontal tube
PublikacjaNanofluids came to be seen as a new generation of coolants, both in single- and two phase systems. Furthermore, nanofluids or nanocomposites may be used as a media in a thermal energy storage (TES) in such systems as sensible heat storage (SHS) and phase change materials (PCM). In the SHS systems the dominating mechanism of the heat transfer is natural convection. However, in the literature only a few investigations of free convection...
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Bead-on-plate welding on S235JR steel by underwater local dry chamber process
PublikacjaThe article presents the results of the effect of parameters of underwater local dry chamber welding on the properties of padding welds. The effect of heat input and the type of shielding gas on the structure and hardness of welds was established. the functions for estimating the maximum hardness of the heat affected zone have been also elaborated.
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MOŻLIWOŚĆ WYKORZYSTANIA ELEKTROWNI JĄDROWEJ JAKO ŹRÓDŁA ENERGII ELEKTRYCZNEJ I CIEPLNEJ
PublikacjaW niniejszym artykule przedstawiono zagadnienia związane z możliwością pracy elektrowni jądrowej (EJ) również w charakterze źródła ciepła, a więc w warunkach skojarzonego wytwarzania energii elektrycznej oraz ciepła. Rozpatrzono dwa poziomy mocy cieplnych oddawanych do systemów ciepłowniczych. Przeprowadzone wstępnie badania techniczne i ekonomiczne dla lokalizacji elektrowni jądrowej nad Jeziorem Żarnowieckim potwierdziły potencjalną...
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Phoenixin-14 effect on viability and THBS2 and CDH1 expression in 12Z endometriosis cell line
Dane BadawczePhoenixin-14 is a neuropeptide produced by the paraventricular nuclei of the anterior hypothalamus that regulates reproductive system functions. Its level in patients with endometriosis is reduced and may be the cause of dysregulated HPG-axis. Our study tested endometriosis-specific concentrations of PNX-14 on endometrial epithelial cell line 12Z in...
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Impact of configuration of earth continuity conductor on induced sheath voltages in power cables
PublikacjaIn high voltage power cable systems a problem of induced sheath voltages exist. Due to these voltages electric shock and damage of non-metallic outer sheath of the cables may occur. Exposure to voltage of the outer sheath may be very high in case of earth fault with high value of earth current. In order to reduce induced sheath voltages an earth continuity conductor (conductors) along power cables is applied. Configuration of this...
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On the Origin of Protein Superfamilies and Superfolds
PublikacjaDistributions of protein families and folds in genomes are highly skewed, having a small number of prevalent superfamiles/superfolds and a large number of families/folds of a small size. Why are the distributions of protein families and folds skewed? Why are there only a limited number of protein families? Here, we employ an information theoretic approach to investigate the protein sequence-structure relationship that leads to...
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Molecular Targets for Anticandidal Chemotherapy
PublikacjaA relatively small number of anticandidal chemotherapeutics used in clinical practice is at least in part consequence of a limited number of their molecular targets: ergosterol in the membrane, lanosterol demethylase, b(1!3) glucan synthase, and DNA/RNA biosynthesis. Much more potential novel targets have been revealed by the comparative genomic studies identifying essential genes unique for Candida albicans or resulted from recognition...
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Genetic and Epigenetic Aspects of Atopic Dermatitis
PublikacjaAtopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune responses and environmental factors inducing the disease is also noted. Recent studies point to the key role of epigenetic changes in the development of the disease. Epigenetic modifications...
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Hydration of Simple Model Peptides in Aqueous Osmolyte Solutions
PublikacjaThe biology and chemistry of proteins and peptides are inextricably linked with water as the solvent. The reason for the high stability of some proteins or uncontrolled aggregation of others may be hidden in the properties of their hydration water. In this study, we investigated the effect of stabilizing osmolyte–TMAO (trimethylamine N-oxide) and destabilizing osmolyte–urea on hydration shells of two short peptides, NAGMA (N-acetyl-glycine-methylamide)...
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Properties of Different Varieties of Durian
PublikacjaDurian (Durio zibethinus Murr.), like many other exotic, tropical, and conventional fruits, is important in the prevention of different diseases. In this study, the characterization of the main bioactive compounds of the most popular cultivars of durian and their properties are described. The changes in the quality indices of the antioxidant status were determined by CUPRAC, ABTS, FRAP, DPPH, and ORAC assays. The profiling of phytochemicals...
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Testing an evaporator operation with a concave manifold, condenser temperature 30, evaporator temperature 70 and preheater temperature 60
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a bifurcation manifold, condenser temperature 20 and evaporator temperature 85
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a concave manifold, condenser temperature 30, evaporator temperature 70 and preheater temperature 40
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a trapezoidal manifold, condenser temperature 90 and evaporator temperature 90
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a bifurcation manifold, condenser temperature 20 and evaporator temperature 70
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a rectangular manifold, condenser temperature 30 and evaporator temperature 90
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a trapezoidal manifold, condenser temperature 70 and evaporator temperature 60
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a bifurcation manifold, condenser temperature 20 and evaporator temperature 95
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Testing an evaporator operation with a bifurcation manifold, condenser temperature 20 and evaporator temperature 90
Dane BadawczeThe experiment was conducted to test the evaporator operation. The heat exchanger was equipped with minigeometry (set of 50 parallel minichannels or single minigap). The studies were conducted for various mass flow rate of the working fluid and for various temperatures at the inlet of the evaporator. Accurate information about the test rig, the parameters...
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Phase Change Thermal Energy Storage – The Experience of the Materials Preparation for the Specific Applications.
PublikacjaThermal energy storage and temperature stabilization is very important in many engineering applications. There are three kinds of thermal energy storage: sensible heat storage, latent heat storage and reversible chemical reaction heat storage. Phase change materials (PCM) absorb, store and release large amounts of energy in the form of latent heat, at constant temperature, called the transition temperature. The amount of heat...
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Evaluation and cellular responses of modulators of TRF1/TRF2 protein’s function as potential anticancer drugs interfering with telomeric shelterin’s function
PublikacjaA number of proteins that interact with telomeres have been identified in human cells, indicating the high plasticity of human nucleoprotein complex organization. The most important complex is the "shelterin" complex, which consists of six proteins: TRF1, TRF2, TIN2, POT1, TPP1. The TRF1 and TRF2 directly bind to telomeric double-stranded DNA and the TIN2 protein. The TIN2 protein also binds to the TPP1 protein, stabilizing the...
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Thermodynamic analysis of the Compressed Air Energy Storage system coupled with the Underground Thermal Energy Storage
PublikacjaImprovement of flexibility is one of the key challenges for the transformation of the Polish Power System aiming at a high share of renewable energy in electricity generation. Flexible and dispatchable power plants will contribute to this ongoing transformation process as they compensate for fluctuations in electricity generation from renewable energy sources such as wind and photovoltaics. In this context, CAES storage tanks are...
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The Effects of Pin Profile on HDPE Thermomechanical Phenomena during FSW
PublikacjaFriction stir welding (FSW) of polymeric materials has recently attracted significant attention. Herein, we present the effect of the tool pin profile on the FSW of high-density polyethylene (HDPE) joints through joint experimental analysis and thermomechanical simulations. For analysis of pin profile effects on the thermomechanical properties of HDPE joints, frustum (FPT), cubic (CPT), and triangular (TPT) pin shapes were selected...
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Total electrical conductivity data of (Cr,Fe,Mn,Co,Ni)3O4 High-entropy spinel oxide thin films deposited on amorphous SiO2 substrate by spray pyrolysis techniqe
Dane BadawczeThis dataset includes electrical conductivity measurements results measured by van der pauw technique up to 900oC.
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Nowoczesne metody termochemicznej konwersji biomasy w paliwa gazowe, ciekłe i stałe = Modern methods of thermochemical biomass conversion into gas, liquid and solid fuels
PublikacjaBiomass utilization through direct- or co-combustion with coal, based on coal, hydrogen and oxygen compounds chemical energy conversion into heat in boilers, is simultaneously the cheapest and - according to experts - economically least effective solution. In case of heat and electricity production in cogeneration process in biomass fueled heat and power stations (wood, straw, energetic plants, RDF etc), investment costs are little...
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Energy conversion in systems-contained laser irradiated metallic nanoparticles - comparison of results from analytical solutions and numerical methods
PublikacjaThis work introduces the theoretical method of metallic nanoparticles’ (NPs’) heat and mass transfer where the particles are coated on a surface (base), together with considering the case wherein nanoparticles move freely in a pipe. In order to simulate the heat transfer, energy and radiative transfer equations are adjusted to the considered issue. NPs’ properties are determined following the nanofluidic theories, whereas absorption...