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Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization
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Tissue Rheology as a Possible Complementary Procedure to Advance Histological Diagnosis of Colon Cancer
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Serum MicroRNAs as Xerostomia Biomarkers in Patients With Oropharyngeal Cancer Undergoing Radiation Therapy
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Bayesian multilevel model of micro RNA levels in ovarian-cancer and healthy subjects
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Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies
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From chemoresistance to cancer stem cells: the case of BRCP/ABCG2 half transporter
PublikacjaLudzkie białko ABCG2 jest pompą typu ABC tworzącą homodimery i aktywnie transportującą leki i inne substraty naturalne i syntetyczne. Nadekspresja tego białko prowadzi do oporności na leki przeciwnowotworowe. Białko ABCG2 występuje w wielu formach zmutowanych, różniących się własnościami substratowymi, stąd istotne dla oporności na leki jest jaka forma genu i białka ABCG2 ulega nadekspresji w komórce. Ostatnie badania wskazują,...
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Vimentin immunoexpression and its prognostic activity in colon cancer among Caucasian patients
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Near-Infrared Fluorescence Image-Guided Surgery in Esophageal and Gastric Cancer Operations
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The INTERSTROKE Study: hypertension is by far the most important modifiable risk factor for stroke
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How should we teach cardiopulmonary resuscitation? Randomized multi-center study
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
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Modern information technology as a factor supporting participation in physical culture of a contemporary man
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Can popular films instil carcinophobia? Images of cancer in popular Polish cinema
PublikacjaIntroduction: Although cancer is currently considered a serious socio-medical challenge and health education in Poland has been positioned as a public health priority, the impact of popular culture on people’s ideas about cancer has been neglected. This study therefore aims to analyse the way popular Polish films portray cancer and the experience of cancer.Material and Methods: Seven popular Polish films featuring cancer...
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The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
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FGF7 / FGFR2 – JunB signalling counteracts the effect of progesterone in luminal breast cancer
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Phytotoxic Metabolites Produced by Diaporthella cryptica, the Causal Agent of Hazelnut Branch Canker
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THE INVESTMENT ENVIRONMENT MANAGEMENT SYSTEM IN THE FRAMEWORK OF LEGAL SUPPORT AS A FACTOR OF NATIONAL SAFETY
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Risk factors assessment and risk prediction models in lung cancer screening candidates
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Caffeine Inhibits Differentiation Of Lung Cancer Stem Cells By Modulating Their Respiratory Metabolism
PublikacjaIt is ell established that many tumor types contain a fraction of cells, with stem cell-like properties, called cancer stem cells (CSCs), that are resistant to apoptosis induced by therapeutic agents. The presence of CSCs may explain why a standard anticancer treatment, that eliminates only differentiated cancer cells, does not lead to cancer cure.We previously showed the existence of caffeine-sensitive mechanism that controls...
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Methods of mapping out the route contour of a railway line on the measured rail irregularities
PublikacjaStosowane obecnie toromierze elektroniczne wykorzystywane są przede wszystkim do pomiaru geometrii toru. Dane z pomiarów nierówności mogą być również wykorzystane w procesie projektowania regulacji toru (np. podczas usuwania dołków). W mongrafii przedstawiono metodę wyznaczenie profilu podłużnego linii kolejowej na podstawie pomierzonych nierówności pionowych. Wyznaczony w ten sposób profil w dalszym etapie wykorzystany by był...
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Hydrophobic and hydrophilic properties of pollutants as a factor influencing their redistribution during snowpack melt
PublikacjaGlaciers accumulate organic pollutants delivered by snow. However, our understanding of the exact dynamics of organic pollutants in the snowpack relies primarily on laboratory experiments and mathematical models. To fill the gap related to the detailed field data, we have conducted observations of melting snow profiles in two locations and three different stages of melting on one High Arctic glacier, as well as in superimposed...
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Can popular films instil carcinophobia? Images of cancer in popular Polish cinema
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Long-Term Outcomes of Laparoscopic Sleeve Gastrectomy—a Single-Center, Retrospective Study
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Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment
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Temperature effect on the current-voltage characteristic fill factor for the silicon solar cells
PublikacjaW pracy przedstawiono badania wpływu temperatury pracy krzemowych ogniw fotowoltaicznych na wartość współczynnika wypełnienia charakterystyki prądowo- napięciowej (FF). Efekty dyfuzyjne w obszarze złącza oraz rekombinacja nośników ładunku ograniczają wartość współczynnika wypełnienia charakterystyki. Spadek tej wartości wynika głównie ze wzrostu wartości rezystancji szeregowej rs. Na rezystancję szeregową składają się: opór emitera...
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The formal safety assessment and influence of human factor in application to chosen ship's type
PublikacjaTragedia jednego ze statków typu ro-ro pokazała podatność tego typu statków na utratę stateczności, przewrócenie się, a w ostateczności zatonięcie. Wszystkie ro-rowce charakteryzują się małym zanurzeniem, a wynurzona część kadłuba podatna jest na działanie wiatru. Jeżeli dodatkowo w takich warunkach dochodzi element nieprawidłowego rozmieszczenia pojazdów i ich słabego zamocowania to groźba przesunięcia ładunku staje się realna....
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Strength deterioration of 26H2MF and 34HNM steels used in ship engines: hydrogen factor
PublikacjaBadano podatność stali 26H2MF i 34HNM poddanych różnej obróbce cieplnej na niszczenie wodorowe. Badania wykonano metodą powolnego rozciągania z szybkością 10-6 s-1. Określano wytrzymałość, wydłużenie, przewężenie i energię zniszczenia. Stwierdzono znaczna degradację w 0,01 M kwasie siarkowym z dodatkiem arszeniku. Wykazano istnienie korelacji między obróbką cieplną i stopniem degradacji. Efekty przypisano pułapkowaniu wodoru.
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High Q-factor Microwave Fabry-Perot Resonator With Distributed Bragg Reflectors
PublikacjaZrealizowany został rezonator Fabry-Perot pracujący na częstotliwości 39 GHz i wykorzystujący dwie pary ćwierćfalowych kwarcowych reflektorów Bragga. Dla fali o długości 98.26 mm otrzymano dobroć ok. 560,000, co oznacza 4.3-krotny wzrost w porównaniu z identycznym rezonatorem bez reflektorów Bragga. Analizę problemu wykonano przy pomocy metody różnic skończonych w dziedzinie częstotliwości (FDFD) i porównano z uproszczonym rozwiązaniem...
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Quinoline-based thiazolyl-hydrazones target cancer cells through autophagy inhibition
PublikacjaHeterocyclic pharmacophores such as thiazole and quinoline rings have a significant role in medicinal chemistry. They are considered privileged structures since they constitute several Food and Drug Administration (FDA)-approved drugs for cancer treatment. Herein, we report the synthesis, in silico evaluation of the ADMET profiles, and in vitro investigation of the anticancer activity of a series of novel thiazolyl-hydrazones based...
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Deep Learning-Based, Multiclass Approach to Cancer Classification on Liquid Biopsy Data
PublikacjaThe field of cancer diagnostics has been revolutionized by liquid biopsies, which offer a bridge between laboratory research and clinical settings. These tests are less invasive than traditional biopsies and more convenient than routine imaging methods. Liquid biopsies allow studying of tumor-derived markers in bodily fluids, enabling the development of more precise cancer diagnostic tests for screening, disease monitoring, and...
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Environmental exposure to cadmium in breast cancer – association with the Warburg effect and sensitivity to tamoxifen
PublikacjaThe association between cadmium and breast cancer remains unexplained due to inconsistent epidemiological data and unknown underlying mechanisms. This study aimed to assess the relationship between environmental exposure to cadmium and the Warburg effect in breast cancer and, thus, its possible interference with breast cancer treatment. The observational study in two groups of breast cancer patients indicated a positive correlation between...
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Melanoma skin cancer detection using mask-RCNN with modified GRU model
PublikacjaIntroduction: Melanoma Skin Cancer (MSC) is a type of cancer in the human body; therefore, early disease diagnosis is essential for reducing the mortality rate. However, dermoscopic image analysis poses challenges due to factors such as color illumination, light reflections, and the varying sizes and shapes of lesions. To overcome these challenges, an automated framework is proposed in this manuscript. Methods: Initially, dermoscopic...
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Constant-Factor Approximation Algorithm for Binary Search in Trees with Monotonic Query Times
PublikacjaWe consider a generalization of binary search in linear orders to the domain of weighted trees. The goal is to design an adaptive search strategy whose aim is to locate an unknown target vertex of a given tree. Each query to a vertex v incurs a non-negative cost ω(v) (that can be interpreted as the duration of the query) and returns a feedback that either v is the target or the edge incident to v is given that is on the path towards...
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Potential plasma biomarkers of bladder cancer identified by proteomic analysis: A pilot study
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Knowledge and technology transfer in the Center for Scientific and Technical Information of the Wrocław University of Technology
PublikacjaKnowledge and Technology Transfer between a university and economic operators affects innovation and growth of competitiveness, as well as the development of a knowledge-based society. In the structures of Wroclaw University of Technology, regarded as one of the best and the most innovative technical universities in Poland, a number of units responsible for a wide understanding cooperation with the economy have been established....
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VISUALIZATION OF SCANTER AND ARPA RADAR DATA IN THE DISTRIBUTED TELEINFORMATION SYSTEM FOR THE BORDER GUARD
PublikacjaMonitoring of country maritime border is an important task of the Border Guard. This activity can be enhanced with the use of the technology enabling gathering information from distributed sources, processing of that information and its visualization. The paper presents the next stage of development of the STRADAR project (Streaming of real-time data transmission in distributed dispatching and teleinformation systems of the Border...
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Interaction of the conserved region 4.2 of sigma(E) with the RseA anti-sigma factor
PublikacjaEo-E RNA polymerase transcribes a regulon of folding factors for the bacterial envelope and is induced by physical and chemical stresses. The RseA anti-sigma factor inhibits the activity of Esigma(E) RNA, polymerase. It is shown here that the N-terminal portion of sigma(E), residues 1-153, binds core RNA polymerase. RseA interacts with residues 154-191 of sigma(E), a site that is homologous to region 4, the sigma factor binding...
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Effect of package type on selected parameters of nutritional quality of chill-stored white sauerkraut
PublikacjaBrassica vegetables, including white cabbage, both fresh and sour (Brassica oleracea L. var. capitata L.), contain a lot of valuable metabolites which are effective in chemoprevention of cancer as documented by numerous studies. This work investigates the effect of different packaging types; low density polyethylene (PE-LD) and metalized polyethylene terephthalate (PET met/PE) with polyethylene bags on selected quality parameters in...
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Chapel at St. Joseph's Church in Gdańsk
PublikacjaThe subject of this article is the chapel located in the former Gdańsk Carmelite monastery complex. The results of the architectural research carried out in it in 2014–2015 are presented. As a result, the time and purpose of the building’s construction were established. The original appearance and traces of later alterations were also recognised. The recesses found on the longitudinal walls, of similar dimensions, not reaching...
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Radiation Therapy–Related Changes in Serum Proteome and Lipidome Are Primarily Associated With a Type of Acute Toxicity: Comparison of Radiation-Induced Effects in Patients Treated Because of Head and Neck Cancer or Prostate Cancer
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Collocations et représentation féminine dans les oeuvres de Colette : Une analyse linguistique et littéraire
PublikacjaSidonie-Gabrielle Colette played a significant role in the development of French literature. Her novels vividly depict independent and self-aware women, thereby reflecting the author herself. Colette’s works have captured the attention of researchers and have been the subject of numerous studies. In this proposed research, an interdisciplinary approach combining literary and linguistic perspectives is adopted to explore Colette’s...
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From Sequential to Parallel Implementation of NLP Using the Actor Model
PublikacjaThe article focuses on presenting methods allowing easy parallelization of an existing, sequential Natural Language Processing (NLP) application within a multi-core system. The actor-based solution implemented with the Akka framework has been applied and compared to an application based on Task Parallel Library (TPL) and to the original sequential application. Architectures, data and control flows are described along with execution...
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Evolutionary sets of safe ship trajectories with speed reduction manoeuvres within traffic separation schemes
PublikacjaIn the previous paper the author presented the evolutionary ship trajectory planning method designed to support Traffic Separation Schemes (TSS). This time the extensions of this method are described which allow to combine evolutionary trajectory planning with speed reduction manoeuvres. On TSS regions with higher than usual density of traffic and smaller distances between ships, the course alterations alone are not always sufficient...
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Kompozyt przekładkowy GFRP z rdzeniem PET w powłokowej konstrukcji kładki dla pieszych
PublikacjaW artykule przedstawiono badania doświadczalne materiału przekładkowego zastosowanego w innowacyjnym rozwiązaniu mostu dla pieszych. Kładka o konstrukcji powłokowej wykonana jest z kompozytu przekładkowego i jest wytworzona w całości bez złączy w technologii infuzji. Artykuł przedstawia wyniki badań doświadczalnych okładzin, pianki PET oraz testy 3- i 4-punktowego zginania belek wykonanych z materiału przekładkowego. Uzyskane wyniki...
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Local Structure and Stability of SEI in Graphite and ZFO Electrodes Probed by As K-edge Absorption Spectroscopy
PublikacjaThe evolution of the solid electrolyte interphase (SEI) during the first Li uptake in advanced Li-ion electrodes is studied by X-ray absorption spectroscopy (XAS). The As atoms present in the electrolyte solution were used as a local probe for monitoring the SEI growth on different electrodes. High-quality As K-edge spectra were collected in fluorescence mode for a set of graphite and carbon-coated ZnFe2O4 electrodes. XAS measurements...
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The influence of street conditions on sea buckthorn fruit quality and content of micro- and macronutrients in berries and in soil
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A model of liquid film breakdown formed due to impingement of a two-phase jet on a horizontal surface
PublikacjaThe present work aims to provide an explanation to the phenomenon of breakdown of the thin liquid film created by impinging two-phase, liquid-gas jet. Existing in the literature models describe merely thebreakdown of single phase liquid films. The model presented here is based on examination of mass and energy equations under the applied criterion of the minimum of total energy. That allows to determinethe minimum thickness of...
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Sea navigation-based Thai Canal implication: an analysis of its effect on the Vietnamese maritime industry
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Temporal Satellite Images in The Process of Automatic Efficient Detection of Changes of the Baltic Sea Coastal Zone
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The bioactivity studies of drug-loaded mesoporous silica-polydimethylsiloxane xerogels using FTIR and SEM/XEDS
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