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Wyniki wyszukiwania dla: biotechnologie elsi
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Development and Validation of SPE-HPLC-MS/MS Method for Determining Cyclophosphamide in Surface Waters
PublikacjaA rapid and selective method for trace amounts determination of cyclophosphamide in surface water samples has been developed. A solid phase extraction SPE method for extraction and clean-up procedure has been optimized for determination by reversed-phase high-performance liquid chromatography with tandem mass spectrometry. The analyses proceed in the positive ion mode by means of the electrospray ionization method (ESI). Clean...
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Stabilities of bisphenol A diglycidyl ether, bisphenol F diglycidyl ether, and their derivatives under controlled conditions analyzed using liquid chromatography coupled with tandem mass spectrometry
PublikacjaBisphenol A diglycidyl ether (BADGE), bisphenol F diglycydyl ether (BFDGE), and their related compounds are widely used as precursors in production of epoxy resins. The high reactivity of these compounds makes the development of analytical methodologies that ensure appropriate metrological accuracy crucial. Consequently, we aimed to determine whether and to what extent the composition of the solution and storage conditions affect...
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Multidirectional Characterization of Phytochemical Profile and Health-Promoting Effects of Ziziphora bungeana Juz. Extracts
PublikacjaZiziphora species (Lamiaceae) have been used in traditional medicine as sedatives, anti-septics, carminatives, or expectorants. Despite their common applications in phytotherapy, there is still lack of evidence about the composition of their extracts and its impact on biological properties of the plants. The aim of this study was to evaluate the content of Ziziphora bungeana, a less studied species growing in Kazakhstan, using...
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Pharmaceuticals and another groups of emerging contaminants: Occurrence and sources in Admiralty Bay (King George Island, Maritime Antarctica)
PublikacjaEveryday live activities may introduce a wide range of chemicals into wastewater systems. In this study presence of selected types of pharmaceuticals from cardiovascular system group, nervous and muscolo-skeleton system group, antimicrobial agents, genitourinary and sex hormones were tested in the wastewater from H. Arctowski Antarctic station. Moreover, the receiver of discharged wastewater (Admiralty Bay) were also studied. Considering...
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Jakub Baczyński-Keller
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Edyta Składanek
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Judyta Kosińska mgr inż.
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Method-Dependent Epidemiological Cutoff Values for Detection of Triazole Resistance in Candida and Aspergillus Species for the Sensititre YeastOne Colorimetric Broth and Etest Agar Diffusion Methods
PublikacjaAlthough the Sensititre Yeast-One (SYO) and Etest methods are widely utilized, interpretive criteria are not available for triazole susceptibility testing of Candida or Aspergillus species. We collected fluconazole, itraconazole, posaconazole, and voriconazole SYO and Etest MICs from 39 laboratories representing all continents for (method/agent-dependent) 11,171 Candida albicans, 215 C. dubliniensis, 4,418 C. glabrata species complex,...
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Marika Mróz mgr inż.
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Małgorzata Borecka
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Anna Monika Kowalska mgr
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Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7
PublikacjaBackground The compound 9-(2′-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), the promising antitumor agent developed in our laboratory was determined to undergo phase I metabolic pathways. The present studies aimed to know its biotransformation with phase II enzymes – UDP-glucuronosyltransferases (UGTs) and its potential to be engaged in drug-drug interactions arising from the modulation of UGT activity. Methods UGT-mediated...
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Application of analytical methods for the determination of bioactive compounds in some berries
PublikacjaFluorometry, ESI-MS, FTIR, and radical scavenging assays were used for characterization of bioactive compounds and the levels of their antioxidant activities. Polyphenols, flavonoids, anthocyanins, and ascorbic acid and the level of antioxidant activity of water extracts of “Murtilla-like” [Myrteola nummularia (Poiret) Berg.], and other widely consumed berries were determined and compared. The contents of bioactive compounds and...
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The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors—In Silico and In Vitro Studies
PublikacjaThe aim of the study was to present the fingerprint of different Lepidium peruvianum tu- ber extracts showing glucosinolates-containing substances possibly playing an important role in preventinting dementia and other memory disorders. Different phenotypes of Lepidium peruvianum (Brassicaceae) tubers were analysed for their glucosinolate profile using a liquid chromatograph coupled with mass spectrometer (HPLC-ESI-QTOF-MS/MS platform)....
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General Genetics QUIZZ
Kursy OnlineCelem wykładu będzie zapoznanie Studentów z najważniejszymi odkryciami, prawami i terminami genetyki. Wykład będzie obejmował kluczowe zagadnienia genetyki: zasady dziedziczenia cech i chorób, mechanizmy regulacji ekspresji genów i mechanizmy zmienności genetycznej. Wykład będzie kładł duży nacisk na wyjaśnienie, szczególnie istotnego dla biotechnologów, molekularnego podłoża dziedziczności, zmienności genetycznej i regulacji...
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Challenges and Possibilities of Deep Eutectic Solvent-Based Membranes
PublikacjaDeep eutectic solvents (DES) are a category of a new class of solvents that can overcome some of the main drawbacks of typical solvents and ionic liquids (ILs). DES have been widely investigated and applied by the research community in several applications since their invention. Over the past years, the use of DES has been directed to the production of new materials and items for new products and processes. This is the case for...
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Jolanta Małgorzata Kochel-Karakulska dr hab.
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Wioletta Agnieszka Biel dr hab. inż.
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Beata Seremak dr hab. inż.
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Mateusz Karol Bucław dr inż.
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Małgorzata Anna Szewczuk dr hab. inż.
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Wiesław Franciszek Skrzypczak prof. dr hab. inż.
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Daniel Zaborski dr hab. inż.
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Arkadiusz Pietruszka dr hab. inż.
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Tomasz Stankiewicz dr hab. inż.
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Piotr Stefan Sablik dr hab. inż.
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Katarzyna Marta Kavetska prof. dr hab. inż.
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Katarzyna Aleksandra Wojdak-Maksymiec dr hab. inż.
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Andrzej Dybus dr hab. inż.
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Agnieszka Herosimczyk dr hab. inż.
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Jan Mieczysław Udała prof. dr hab. inż.
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Katarzyna Pęzińska-Kijak dr
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Daria Weronika Ciecholewska-Juśko dr inż.
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Karol Zdzisław Fijałkowski prof. dr hab. inż.
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Piotr Baranowski prof. dr hab.
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Małgorzata Ożgo prof. dr hab. inż.
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Ewa Jolanta Czerniawska-Piątkowska prof. dr hab. inż.
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Dariusz Feliks Gączarzewicz dr hab.
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Alicja Dratwa-Chałupnik dr hab. inż.
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Iwona Szatkowska prof. dr hab. inż.
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Wilhelm Jan Grzesiak prof. dr hab. inż.
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Radosław Drozd dr hab. inż.
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Magdalena Joanna Jędrzejczak-Silicka dr inż.
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Bogumiła Małgorzata Pilarczyk prof. dr hab. inż.
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Tadeusz Karamucki dr hab. inż.
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Danuta Jadwiga Szczerbińska prof. dr hab. inż.
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Hanna Iwona Kulig dr hab.
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Anita Kołodziej-Skalska dr hab.
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Angelika Zuzanna Cieśla dr hab. inż.
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Barbara Krystyna Błaszczyk dr hab. inż.
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