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Wyniki wyszukiwania dla: Catalogs
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Selective Cytostatic and Cytotoxic Anticancer Effects of Bisfunctional Agents: A Strategy for the Design of DNA Binding Agents
PublikacjaVarious agents have been synthesized and proved useful for the National Cancer Institute's anticancer testing as potential new drugs, but most agents suffer side effects from their limited selectivity against cancer cells over healthy ones. Therefore, this paper attempts to describe drugs in terms of the level of tumor cell selectivity which they possess to define the features of mols. that are essential for useful cytotoxicity....
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Synthesis and biological evaluation of thiophosphate tricyclic coumarin derivatives as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) enzyme inhibition is an important approach to the management of hormone-dependent breast cancer. In this paper, we report convenient methods for the synthesis and biological evaluation of thiophosphate tricyclic coumarin analogs exhibiting STS activity. The described methods are based on the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-2-one, 3-hydroxy- 7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one,...
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Laser-assisted approach for improved performance of Au-Ti based glucose sensing electrodes
PublikacjaThis paper focuses on the synthesis route and electrochemical properties of electrocatalytic material based on gold nanoparticles (NPs) embedded in a structured titanium template obtained via optimized anodization, chemical etching and laser processing. SEM inspection reveals the presence of Au NPs (60–90 nm in diameter) sited in the titanium foil cavities. Performed electrochemical measurements enable nomination of the set of working...
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Rola kluczowych kompetencji organizacji w realizacji strategii biznesu
PublikacjaW dobie globalizacji wydaje się, że dobra strategia organizacji powinna obejmować prognozę przyszłej sytuacji branży oraz być ukierunkowana na posiadane aktywa materialne i niematerialne. Znalezienie odpowiednich proporcji pomiędzy ciągłą strategiczną zwinnością a trwałą operacyjną doskonałością jest dla wielu organizacji bardzo trudnym zadaniem, zatem zaczęto eksponować rolę kapitału intelektualnego jako kluczowego czynnika sukcesu....
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Infrastruktura dla Pomorskich Tras Rowerowych R-10 i R-9 o znaczeniu międzynarodowym. Opis założeń projektowych
PublikacjaProjekt koncepcji zagospodarowania rowerowych miejsc postojowych powstał w ramach przedsięwzięcia strategicznego "Pomorskie Trasy Rowerowe o znaczeniu międzynarodowym R-10 i Wiślana Trasa Rowerowa (R-9)", którego inicjatorem i koordynatorem był Departament Turystyki i Promocji Urzędu Marszałkowskiego Województwa Pomorskiego. Założeniem przedsięwzięcia było wybudowanie dwóch oznakowanych tras rowerowych z dedykowana...
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Baltic Sea climate fever. Creative solutions for waterfront cities in the context of climate change
PublikacjaThe goal of the research is to recognize climate change impact on Baltic Sea cities and description of strengths and weaknesses of cities strategies and activities. The range of research has been limited to 3 cities in the Baltic Sea (Copenhagen, Gothenburg, Tallinn) and Tricity as an area for which recommendations will be proposed actions in the field of adaptation to climate change. Recommendations for Tricity as a unique group...
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Do Phenyl Substituents Affect the Properties of Azobenzocrown Derivatives?
PublikacjaNew products of photo- and thermal rearrangements of 19-membered azoxybenzocrown with phenyl substituents in benzene rings in the para positions to oligooxyethylene fragments are characterized. The yields of photochemical transformations depend on the solvent. Para-hydroxyazocrown is formed with yields over 50% in propan-2-ol. Ortho-hydroxyazobenzocrown is obtained with yields up to 70% in toluene/acetic acid mixture. Macrocyclic...
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Binary Mixtures of Selected Bisphenols in the Environment: Their Toxicity in Relationship to Individual Constituents
PublikacjaBisphenol A (BPA) is one of the most popular and commonly used plasticizer in the industry. Over the past decade, new chemicals that belong to the bisphenol group have increasingly been used in industrial applications as alternatives to BPA. Nevertheless, information on the combined effects of bisphenol (BP) analogues is insufficient. Therefore, our current study aimed to find the biological response modulations induced by the...
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Active Site Architecture and Reaction Mechanism Determination of Cold Adapted beta-D-galactosidase from Arthrobacter sp. 32cB
PublikacjaArthbetaDG is a dimeric, cold-adapted beta-D-galactosidase that exhibits high hydrolytic and transglycosylation activity. A series of crystal structures of its wild form, as well as its ArthbetaDG_E441Q mutein complexes with ligands were obtained in order to describe the mode of its action. The ArthbetaDG_E441Q mutein is an inactive form of the enzyme designed to enable observation of enzyme interaction with its substrate. The...
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"Spuścizna Rzeczpospolitej Obojga Narodów" : polskie, litewskie i białoruskie dziedzictwo pozostałe po rodzinie Pusłowskich
PublikacjaCelem pracy jest przedstawienie i porównanie wybranych dokumentów oraz archiwów rękopiśmiennych tworzących spuściznę pozostawioną przez szlachecką rodzinę Pusłowskich, zamieszkałą na terenach Wielkiego Księstwa Litewskiego, w czasach unii połączonego z Królestwem Polskim w Rzeczpospolitą Obojga Narodów. Rodzina ta posiadała majątki na terenie dzisiejszej Litwy i Białorusi od XVI w., a od XVIII w. na terenach polskich będących pod...
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Wykorzystanie metafor w identyfikacji i kształtowaniu postaw przedsiębiorczych
PublikacjaEdukacja przedsiębiorcza odgrywa coraz większą rolę w promowaniu i kształtowaniu zachowań oraz kompetencji przedsiębiorczych młodego pokolenia. W tym kontekście szczególnie podkreśla się znaczenie wykorzystywania nowych, interaktywnych metod i form kształcenia, niezwykle istotnych dla jednego z aspektów edukacji przedsiębiorczej, jakim jest kształcenie kreatywności i proaktywności. Zastosowanie metafor spełnia wymagania stawiane...
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CERTIFICATION SYSTEM AS A TOOL FOR IMPROVING THE SAFETY AND SUSTAINABILITY OF SCHOOL-RELATED TRAVELS
PublikacjaDespite the well-established physical, social, emotional, cognitive, and spatial benefits of active and autonomous school commuting of children and adolescents', many are driven by car. Pilot surveys and field research held in 2019 in 10 Gdansk primary schools confirmed this trend. The article presents a certification system for schools, commissioned by the City of Gdańsk, which is an element of a systemic solution shaping patterns...
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Wpływ stosowania usług Inteligentnych Systemów Transportowych na poziom bezpieczeństwa ruchu drogowego
PublikacjaW artykule opisano założenia projektu pt. "Wpływ stosowania usług Inteligentnych Systemów Transportowych na poziom bezpieczeństwa ruchu drogowego". Projekt jest realizowany w ramach programu Rozwój Innowacji Drogowych (RID) zorganizowanego i finansowanego przez Narodowe Centrum Badań i Rozwoju i Generalną Dyrekcję Dróg Krajowych i Autostrad (umowa nr DZP/RID-I-41/7/NCBR/2016). Celem projektu jest opracowanie narzędzi , które umożliwią...
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Zasada szalonego patchworku – efektuacja jako inspiracja do kształtowania relacji i postaw biznesowych
PublikacjaJedna zzasad efektuacyjnego podejscia do przedsiebiorczosci jest zasada szalonego patchworku (crazy quilt), która dotyczy budowania relacji z otoczeniem biznesowym. Zgodnie z nia przedsiebiorca powinien korzystac zkontaktów zosobami zotoczenia, zbudowanych jeszcze przed załozeniem firmy, atakze aktywnie kształtowac nowe relacje wsrodowisku, wktórym firma działa. Silny networking iznajomosc wielu osób pozwalaja na czerpanie inspiracji...
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Using creative approaches for discovering biomorphic forms for appropriate human habitation in natural environments. Case study of Kashubian Lake District
PublikacjaThe research process consisted of studies of natural and cultural conditions of the Kashubian Lake District This is an area of exceptional natural conditions. For centuries, it has seen human habitation with respect to landscape values. Given its extensive forest cover and the lack of heterogeneity of natural conditions, the area has become an interesting inspiration for the author’s original project. The project is aimed at searching...
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Doing Well by Doing Good- CSR in a Global Context
PublikacjaNowadays, there is a general understanding that stakeholders are crucial for the successful enterprise. There is also a need to think about Corporate Social Responsibility (CSR) in a global context. Never before corporations enjoyed so much power and authority. Corporations need to evolve, re-think their strategies and change their processes accordingly. However, as of now, there is no agreed way of measuring overall sustainability...
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Energy, water detailed usage. Living lab testing for sustainable urban food-water-energy cycle.
Dane BadawczeData set contains detailed, continuous measurements of the usage of water and electrical energy (AC power) in an experimental facility set up in a scientific laboratory (Laboratorium im. B.Niemkiewicza) at the Faculty of Mechanical Engineering and Ocean Technology of the Gdansk University of Technology. The test bed was established in co-operation...
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Energy, water detailed usage. Living lab testing for sustainable urban food-water-energy cycle. Jan. 2022
Dane BadawczeData set contains detailed, continuous measurements of the usage of water and electrical energy (AC power) in an experimental facility set up in a scientific laboratory (Laboratorium im. B.Niemkiewicza) at the Faculty of Mechanical Engineering and Ocean Technology of the Gdansk University of Technology. The test bed was established in co-operation...
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Energy, water detailed usage. Living lab testing for sustainable urban food-water-energy cycle. Dec. 2021
Dane BadawczeData set contains detailed, continuous measurements of the usage of water and electrical energy (AC power) in an experimental facility set up in a scientific laboratory (Laboratorium im. B.Niemkiewicza) at the Faculty of Mechanical Engineering and Ocean Technology of the Gdansk University of Technology. The test bed was established in co-operation...
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Synthesis of phosphono and phosphate derivatives of hydroxyimino-D-alditols as new potential antifungal agents
PublikacjaIn search for new effective we antyfungals we focus on two enzymes involved in biosynthesis of the fungal cell wall. The first enzyme is glucosamine-6-phosphate (GlmS), which catalyzes transformation of D-fructose-6-phosphate (Fru-6P) to D-glucosamine-6-phodphate (GlcN-6P) in the chitin biosynthesis pathway. The second enzyme is phosphomannose isomerase (PMI) repored to play a crucial role in biosynthesis of many mannosylated structures,...
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Renewable Resources for Polyurethanes and Polyurethane Composites: A Review
PublikacjaEach year, more than two million tons of polyurethane is produced in the EU by reacting isocyanates with polyols made from fossil fuel. In addition, there are appreciable quantities of petroleum based functional additives applied in the industry nowadays for both polyols and polyurethane materials. It is therefore of key importance to develop sustainable economically viable polyols with enhanced functionalities, and thereby reducing...
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Elective design II Reinventing Gdańsk / Reinventing Gdynia
Kursy OnlineThe workshop will examine important modern architectural buildings in Gdańsk/ Gdynia in different political, cultural, economic and environmental contexts. The students will be divided into groups. Each group will be led by the curator of the exhibition. They will identify and evaluate the architectural values of the building through analyses, deconstructions and syntheses, focusing on understanding the basic principles of architecture...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.40, b=0.26) and (C=2.80, b=0.25) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for two directional control valves arranged in parallel. Three test configurations were used: (1) being emptied tank -> the first DCV -> ambient atmosphere, (2) being...
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Determination of flow properties of a serial connection of a directional control valve with (C=5.7, b=0.32) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.1, b=0.14) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=7.3, b=0.49) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.8, b=0.25) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=5.5, b=0.37) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=6.4, b=0.45) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=6.2, b=0.38) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.4, b=0.26) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=3.3, b=0.40) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.0, b=0.11) and a air blow gun from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=6.40, b=0.45) and (C=6.00, b=0.25) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in parallel. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=4.40, b=0.42) and (C=7.30, b=0.49) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for two pressure relief valves arranged in parallel. Three test configurations were used: (1) being emptied tank -> the first PRV -> ambient atmosphere, (2) being...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.10, b=0.14) and (C=6.40, b=0.45) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.80, b=0.25) and (C=6.40, b=0.45) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=3.30, b=0.40) and (C=6.00, b=0.25) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in parallel. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=5.70, b=0.32) and (C=6.20, b=0.38) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.10, b=0.14) and (C=7.30, b=0.49) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=4.40, b=0.42) and (C=2.80, b=0.25) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=4.40, b=0.42) and (C=6.20, b=0.38) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for two pressure relief valves arranged in parallel. Three test configurations were used: (1) being emptied tank -> the first PRV -> ambient atmosphere, (2) being...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.40, b=0.26) and (C=2.10, b=0.14) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for two directional control valves arranged in parallel. Three test configurations were used: (1) being emptied tank -> the first DCV -> ambient atmosphere, (2) being...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=5.50, b=0.37) and (C=6.40, b=0.45) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=5.70, b=0.32) and (C=6.40, b=0.45) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=5.30, b=0.38) and (C=2.00, b=0.11) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.80, b=0.25) and (C=3.30, b=0.40) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.80, b=0.25) and (C=2.00, b=0.11) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for two directional control valves arranged in parallel. Three test configurations were used: (1) being emptied tank -> the first DCV -> ambient atmosphere, (2) being...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.00, b=0.11) and (C=6.20, b=0.38) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...
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Determination of flow properties of a parallel connection of two pneumatic elements with (C=2.00, b=0.11) and (C=7.30, b=0.49) from changes in air pressure in a tank being emptied
Dane BadawczeThe aim of the study was to determine the flow properties of parallel connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a pressure relief valve arranged in parallel. Three test configurations were used: (1) being emptied tank -> DCV -> ambient atmosphere,...