Filters
total: 2222
filtered: 1744
displaying 1000 best results Help
Search results for: IMMUNOGLOBULIN-LIKE DOMAIN
-
Investigating Analytics Dashboards’ Support for the Value-based Healthcare Delivery Model
PublicationImproving the value of care is one of the essential aspects of Value-Based Healthcare (VBHC) model today. VBHC is a new HC delivery model which is centered on patient health outcomes and improvements. There is anecdotal evidence that the use of decision aid tools like dashboards can play a significant role in the successful implementation of VBHC models. However, there has been little or no systematic studies and reviews to establish...
-
Modeling of Accidental Bunker Oil Spills as a Result of Ship's Bunker Tanks Rupture - a Case Study
PublicationAIS (Automatic Identification System) data analysis is used to define ship domain for grounding scenarios. The domain has been divided into two areas as inner and outer domains. Inner domain has clear border, which is based on ship dynamic characteristics. Violation of inner domain makes the grounding accident unavoidable. Outer domain area is defined with AIS data analyzing. Outer domain shows the situation of own ship in compare...
-
Effect of convection and microwave heating on the retention of bioactive components in human milk
PublicationBioactive substances are very important components of human milk (HM), especially for premature newborns. The effects of convection (CH) and microwave heating (MWH) at 62.5 and 66 °C, on the level of selected bioactive components of HM: lysozyme (LZ), lactoferrin (LF), secretory immunoglobulin A (sIgA), basal lipase (BL), cytokine TGF-2, vitamin C and total antioxidant capacity (TAC) was compared. Regardless of the used heating methods...
-
UNRES-GPU for Physics-Based Coarse-Grained Simulations of Protein Systems at Biological Time- and Size-Scales
PublicationThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
-
Fast bubble dynamics and sizing
PublicationSingle bubble sizing is usually performed by measuring the resonant bubble response using the Dual Frequency Ultrasound Method. However, in practice, the use of millisecond-duration chirp-like waves yields nonlinear distortions of the bubble oscillations. In comparison with the resonant curve obtained under harmonic excitation, it was observed that the bubble dynamic response shifted by up to 20 percent of the resonant frequency...
-
Enhancing Product Innovation Through Smart Innovation Engineering System
PublicationThis paper illustrates the idea of Smart Innovation Engineering (SIE) System that helps in carrying the process of product innovation. The SIE system collects the experiential knowledge from the formal decisional events. This experiential knowledge is collected from the set of similar products having some common functions and features. Due to the fact that SIE system collects, captures and reuses the experiential knowledge of all...
-
System for characterisation and multidimensional imaging of seafloor using multibeam sonar data
PublicationMultibeam sonars are widely used in applications like high resolution bathymetry measurements, underwater object detection and imaging, etc. Also, they are the promising tool in seafloor characterisation and classification, having several advantages over conventional single beam echosounders. The proposed approach to seafloor classification relies on the combined use of three different techniques. In each of them, a set of descriptors...
-
Application of the discrete Green's function-based antenna simulations for excitation of the total-field/scattered-field interface in the FDTD method
PublicationIn this article, the discrete Green's function formulation of the finite-difference time-domain (DGF-FDTD) method is proposed for simulation of wire antennas irradiating inhomogeneous dielectric scatterers. Surface equivalence theorem in the discrete domain is used to separate the problem into an inhomogeneous domain and a wire antenna that are simulated with the use of FDTD and DGF-FDTD, respectively. Then, the excitation of the...
-
TIME-AND-SPACE STRUCTURE OF FORCE-DRIVEN RIGID SPHEREWAVEFIELD
PublicationThis paper introduces a time-domain, causality-inspired description of a vector-source acoustic wavefield of arbitrary time evolution, where a sphere is a practical realisation of quasi-point contact surface without which a point force would not be able to exert an impact onto non-viscous fluid. At every space location, the resulting acoustic field is described by a pair of physical variables characterising the time evolution of...
-
Review of ship safety domains: Models and applications
PublicationShip safety domain is a term which is widely used in research on collision avoidance and traffic engineering among others. Classic ship domains have been compared in multiple reports. However, up till now there has been no work summing up contemporary research in this field. The paper offers a systematic and critical review of the newer ship domain models and related research. It discusses multiple differences in approach to ship...
-
A Simulative Comparison of Ship Domains and Their Polygonal Approximations
PublicationThe paper investigates the impact of a precise ship domain shape on the size of collision avoidance manoeuvres. The considered collision avoidance manoeuvres include both course and speed alterations. Various ship domains are compared with their polygonal approximations, which vary in the number of points of a domain contour and placement of these points. The best of all considered approximations is determined in the course of...
-
Analysis and interpretation of radiometric signals in a liquid-gas bubble flow
PublicationThe article presents the analysis of signals from a radiometric system consisting of two scintillation probes and two gamma radiation sealed sources. Calculations and interpretation were carried out for the bubble flow of the water-air mixture in the horizontal pipeline. The analysis of the obtained signals was done in time and frequency domain. In the frequency domain, a range of usable frequencies was identified, which were associated...
-
The accuracy of pulse rate estimation from the sequence of face images
PublicationThe goal of this paper is to analyze the accuracy of pulse rate estimation from the sequence of face images. Simulated and real signals were used to evaluate two pulse rate estimators; one for frequency domain and the second one for time domain using the autocorrelation function. The results show that the mean difference between the reference measurements and estimated pulse rate values are about 2bpm. In the analysis of short...
-
Software tool for modelling of mechatronic systems with elastic continua
PublicationThe paper presents a systematic computational package for modelling and analysis of complex systems composed of multiple lumped and distributed parameter subsystems. The constructed computer program enables the frequency domain analysis of a class of linear systems and to obtain reduced order model in the form of bond graph. Obtained modal bond graph can be directly exported into 20-Sim package to further processing including nonlinear...
-
Forecasting of railway track tamping based on settlement of sleepers using fuzzy logic
PublicationThe sleepers in a railway track transfer vertical, transverse and longitudinal loads to the track ballast and subgrade. The sleepers allow for keeping the distance between the rails constant. The thickness of ballast should be between 16 and 35 cm depending on the design standard of the track, and it should be densified where the ballast supports the sleeper. The exploitation causes contamination of the ballast, crushing the material...
-
Cloning, expression in Komagataella phaffii, and biochemical characterization of recombinant sequence variants of Pseudomonas sp. S9 GDSL-esterase
PublicationTwo recombinant Komagataella phaffii (formerly Pichia pastoris) yeast strains for production of two sequential variants of EstS9 esterase from psychrotolerant bacterium Pseudomonas sp. S9, i.e. αEstS9N (a two-domain enzyme consisting of a catalytic domain and an autotransporter domain) and αEstS9Δ (a single-domain esterase) were constructed. However, only one of recombinant K. phaffii strains, namely Komagataella phaffii X-33/pPICZαestS9Δ,...
-
Simulation of Signal Propagation Along Fractional-Order Transmission Lines
PublicationIn this paper, the simulation method of signal propagation along fractional-order (FO) transmission lines is presented. Initially, fractional calculus and the model of FO transmission line are introduced. Then, the algorithm allowing for simulation of the nonmonochromatic wave propagation along FO transmission lines is presented. It employs computations in the frequency domain, i.e., an analytical excitation is transformed to the...
-
FDTD Simulations on Disjoint Domains with the Use of Discrete Green's Function Diakoptics
PublicationA discrete Green's function (DGF) approach to couple disjoint domains in the finite-difference time-domain (FDTD) grid is developed. In this method, total-field/scattered-field (TFSF) FDTD domains are associated with simulated objects whereas the interaction between them is modeled with the use of the DGF propagator. Hence, source and scatterer are simulated in separate domains and updating of vacuum cells, being of little interest,...
-
Detection of dialogue in movie soundtrack for speech intelligibility enhancement
PublicationA method for detecting dialogue in 5.1 movie soundtrack based on interchannel spectral disparity is presented. The front channel signals (left, right, center) are analyzed in the frequency domain. The selected partials in the center channel signal, which yield high disparity with left and right channels, are detected as dialogue. Subsequently, the dialogue frequency components are boosted to achieve increased dialogue intelligibility....
-
Frequent Sequence Mining in Web Log Data
PublicationThe amount of information available even on a single web server can be huge. On the other hand, the amount of visitors (users) can often reach a number of at least six digits. Users vary in gender, age and education, and in consequence their information needs are different. Moreover, they subconsciously expect to get more adequate content after visiting the first few pages. The scope of this kind of problem relates to the domain...
-
Comments on “Closed Form Variable Fractional Time Delay Using FFT”
PublicationIn this letter drawbacks of the aforementioned paper are pointed out. The proposed approach is improved with minor modifications of the discrete frequency response. This allows for design of fractional delay filters which are close to optimal and can be efficiently implemented in the frequency domain using the sliding DFT based structure. Alternatively, the derived equivalent closed form formulae for offset windows can be used...
-
Structural studies of a cold-adapted dimeric Beta-D-galactosidase from Paracoccus sp. 32d
PublicationThe crystal structure of a novel dimeric [beta]-D-galactosidase from Paracoccus sp. 32d (Par[beta]DG) was solved in space group P212121 at a resolution of 2.4 Å by molecular replacement with multiple models using the BALBES software. This enzyme belongs to glycoside hydrolase family 2 (GH2), similar to the tetrameric and hexameric [beta]-D-galactosidases from Escherichia coli and Arthrobacter sp. C2-2, respectively. It is the second...
-
Hybridization of the FDTD method with use of the discrete Green's function
PublicationIn this contribution, a hybrid technique is presented which combines the finite-difference time-domain (FDTD) method and the discrete Green's function (DGF) formulation of this method. FDTD is a powerful technique for the analysis of complex penetrable objects but its application is not efficient when the computational domain includes many free-space cells. Therefore, the hybrid method was developed which is applicable to complex...
-
Cloning, expression, and biochemical characterization of a coldactive GDSL-esterase of a Pseudomonas sp. S9 isolated from Spitsbergen island soil
PublicationAn estS9 gene, encoding an esterase of the psychrotolerant bacterium Pseudomonas sp. S9 was cloned and sequenced. The deduced sequence revealed a protein of 636 amino acid residues with a molecular mass of 69 kDa.Further amino acid sequence analysis revealed that the EstS9 enzyme contained a G-D-S-L motif centered at a catalytic serine, an N-terminal catalytic domain and a C-terminal autotransporter domain. Two recombinant E. coli...
-
Application of PL-Grid Platform for Modeling of the Selected Acoustic Phenomena
PublicationDomain grids are specific computational environments, developed within the PLGrid Plus project. For the Acoustic domain grid two supercomputer grid based services were prepared. Dedicated software consists of the outdoor sound propagation module and psychoacoustical noise dosimeter. The results are presented in a form of maps of sound level and Temporary Threshold Shift (TTS) values, therefore the services may play an informative...
-
Properties of water in the region between a tubulin dimer and a single motor head of kinesin
PublicationA kinesin is a molecular motor that can perform movement on a microtubule track in a stepping-like manner. This motion is connected with processes of association and dissociation of kinesin and tubulin. Water is an important participant in these kinds of molecular interactions. This is why we have decided to investigate the dynamical and structural properties of water in the region between the kinesin catalytic domain and the tubulin...
-
A Semiautomatic Experience-Based Tool for Solving Product Innovation Problem
PublicationIn this paper we present the idea of Smart Innovation Engineering (SIE) System and its implementation methodology. The SIE system is semi-automatic system that helps in carrying the process of product innovation. It collects the experiential knowledge from the formal decisional events. This experiential knowledge is collected from the group of similar products having some common functions and features. The SIE system behaves like...
-
Smart Innovation Engineering Using Set of Experience and Decisional DNA
PublicationKnowledge-based Engineering Systems are founded upon integration of knowledge into computer systems and are one of the core requirements for the future Industry 4.0. Since the fourth industrial revolution is passing through the developing phase, implementation of Cyber-Physical Production Systems require more realistic approach. Knowledge Management and Knowledge Engineering plays an important role in manufacturing industries facing...
-
Bearing estimation using double frequency reassignment for a linear passive array
PublicationThe paper demonstrates the use of frequency reassignment for bearing estimation. For this task, signals derived from a linear equispaced passive array are used. The presented method makes use of Fourier transformation based spatial spectrum estimation. It is further developed through the application of two-dimensional reassignment, which leads to obtaining highly concentrated energy distributions in the joint frequency-angle domain...
-
Bioaugmentation of a sequencing batch reactor with Archaea for the treatment of reject water
PublicationIn this study, the bioaugmentation of a sequencing batch reactor (SBR) for the treatment of reject water from wastewater treatment plant was evaluated. For the bioaugmentation step a product containing an enrichment of microorganisms from the Archaea domain was used to enhance the performance of the reactor for treating reject water. The experiment was carried out in two parallel lab-scale sequencing batch reactors. The first one...
-
Hybrid Technique Combining the FDTD Method and Its Convolution Formulation Based on the Discrete Green's Function
PublicationIn this letter, a technique combining the finite-difference time-domain (FDTD) method and its formulation based on the discrete Green's function (DGF) is presented. The hybrid method is applicable to inhomogeneous dielectric structures that are mutually coupled with wire antennas. The method employs the surface equivalence theorem in the discrete domain to separate the problem into a dielectric domain simulated using the FDTD method...
-
Improving listeners' experience for movie playback through enhancing dialogue clarity in soundtracks
PublicationThis paper presents a method for improving users' quality of experience through processing of movie soundtracks. The dialogue clarity enhancement algorithms were introduced for detecting dialogue in movie soundtrack mixes and then for amplifying the dialogue components. The front channel signals (left, right, center) are analyzed in the frequency domain. The selected partials in the center channel signal, which yield high disparity...
-
Comparative Study of Integer and Non-Integer Order Models of Synchronous Generator
PublicationThis article presents a comparison between integer and non-integer order modelling of a synchronous generator, in the frequency domain as well as in the time domain. The classical integer order model was compared to one containing half -order systems. The half-order systems are represented in a Park d-q axis equivalent circuit as impedances modelled by half-order transmittances. Using a direct method based on the approximation...
-
Determination of the Vehicles Speed Using Acoustic Vector Sensor
PublicationThe method for determining the speed of vehicles using acoustic vector sensor and sound intensity measurement technique was presented in the paper. First, the theoretical basis of the proposed method was explained. Next, the details of the developed algorithm of sound intensity processing both in time domain and in frequency domain were described. Optimization process of the method was also presented. Finally, the proposed measurement...
-
Experience Based Clinical Decision Support Systems: An Overview and Case Studies
PublicationThis chapter briefly overviews the evolution of the application of the Decisional DNA and the Set of Experience Knowledge Structure (SOEKS) in the medical domain and in particular in the specific case of the experience-based decision support systems. Decisional DNA, as a knowledge representation structure, offers great possibilities on gathering explicit knowledge of formal decision events as well as a tool for decision making...
-
A New Expression for the 3-D Dyadic FDTD-Compatible Green's Function Based on Multidimensional Z-Transform
PublicationIn this letter, a new analytic expression for the time-domain discrete Green's function (DGF) is derived for the 3-D finite-difference time-domain (FDTD) grid. The derivation employs the multidimensional Z-transform and the impulse response of the discretized scalar wave equation (i.e., scalar DGF). The derived DGF expression involves elementary functions only and requires the implementation of a single function in the multiple-precision...
-
On possible applications of media described by fractional-order models in electromagnetic cloaking
PublicationThe purpose of this paper is to open a scientific discussion on possible applications of media described by fractional-order (FO) models (FOMs) in electromagnetic cloaking. A 2-D cloak based on active sources and the surface equivalence theorem is simulated. It employs a medium described by FOM in communication with sources cancelling the scattered field. A perfect electromagnetic active cloak is thereby demonstrated with the use...
-
Visual content representation and retrieval for Cognitive Cyber Physical Systems
PublicationCognitive Cyber Physical Systems have gained significant attention from academia and industry during the past few decade. One of the main reasons behind this interest is the potential of such technologies to revolutionize human life since they intend to work robustly under complex visual scenes, which environmental conditions may vary, adapting to a comprehensive range of unforeseen changes, and exhibiting prospective behavior...
-
Reduced-Cost Microwave Modeling Using Constrained Domains and Dimensionality Reduction
PublicationDevelopment of modern microwave devices largely exploits full-wave electromagnetic (EM) simulations. Yet, simulation-driven design may be problematic due to the incurred CPU expenses. Addressing the high-cost issues stimulated the development of surrogate modeling methods. Among them, data-driven techniques seem to be the most widespread owing to their flexibility and accessibility. Nonetheless, applicability of approximation-based...
-
The Effect of Hyperbaric Storage on the Nutritional Value and Retention of Certain Bioactive Proteins in Human Milk
PublicationHuman milk (HM) contains the essential macronutrients and bioactive compounds necessary for the normal growth and development of newborns. The milk collected by human milk banks is stored frozen and pasteurized, reducing its nutritional and biological value. The purpose of this study was to determine the effect of hyperbaric storage at subzero temperatures (HS-ST) on the macronutrients and bioactive proteins in HM. As control samples,...
-
A new Toxoplasma gondii chimeric antigen containing fragments of SAG2, GRA1, and ROP1 proteins—impact of immunodominant sequences size on its diagnostic usefulness
PublicationThis study presents the first evaluation of new Toxoplasma gondii recombinant chimeric antigens containing three immunodominant regions of SAG2, GRA1, and one of two ROP1 fragments differing in length for the serodiagnosis of human toxoplasmosis. The recombinant chimeric antigens SAG2-GRA1-ROP1L (with large fragment of ROP1, 85-396 amino acid residues) and SAG2-GRA1-ROP1S (with a small fragment of ROP1, 85-250 amino acid residues)...
-
Parallel Implementation of the Discrete Green's Function Formulation of the FDTD Method on a Multicore Central Processing Unit
PublicationParallel implementation of the discrete Green's function formulation of the finite-difference time-domain (DGF-FDTD) method was developed on a multicore central processing unit. DGF-FDTD avoids computations of the electromagnetic field in free-space cells and does not require domain termination by absorbing boundary conditions. Computed DGF-FDTD solutions are compatible with the FDTD grid enabling the perfect hybridization of FDTD...
-
Enhanced uniform data sampling for constrained data‐driven modeling of antenna input characteristics
PublicationData-driven surrogates are the most popular replacement models utilized in many fields of engineering and science, including design of microwave and antenna structures. The primary practical issue is a curse of dimensionality which limits the number of independent parameters that can be accounted for in the modelling process. Recently, a performance-driven modelling technique has been proposed where the constrained domain of the...
-
Usage of concentrated spectrogram for analysis of acoustical signals
PublicationA novel precise method of signal analysis in the time-frequency domain is presented. A signal energy distribution is estimated by discard and displacement of energy parts of the classical spectrogram. A channelized instantaneous frequency and a local group delay are used in order to energy replacement. Additionally, newly introduced representations such as: a channelized instantaneous bandwidth and a local group duration are used...
-
GPR simulations for diagnostics of a reinforced concrete beam
PublicationThe most popular technique for modelling of an electromagnetic field, the finite difference time domain (FDTD) method, has recently become a popular technique as an interpretation tool for ground penetrating radar (GPR) measurements. The aim of this study is to detect the size and the position of damage in a reinforced concrete beam using GPR maps. Numerical simulations were carried out using the finite differ-ence time domain...
-
What do hashtags afford in digital fashion communication? An exploratory study on Gucci-related hashtags on Twitter and Instagram.
PublicationBeing enmeshed in a digital environment, we daily produce internet-mediated texts – encompassing several different semiotic codes – accessible on a global scale. Posts on different networks usually contain hashtags, which can be understood as affordances or behavior opportunities. These affordances allow specific actions both from the part of the writer and the reader. They can also be “behavior triggers,” which invite certain...
-
Evaluation Of Single Pole Auto-Reclosing Effectiveness With Nonlinear Secondary Arc Model
PublicationThe paper discusses two evaluation methods of single pole auto-reclosing process effectiveness in HV transmission lines. Secondary arc current and recovery voltage results obtained by load flow calculation are compared to the results obtained by the time domain simulations. Moreover, a non-linear secondary arc implementation is presented. The authors indicate, that precise representation of secondary electric arc leads to more...
-
A Set of Experience-Based Smart Synergy Security Mechanism in Internet of Vehicles
PublicationIn this article, we introduce a novel security mechanism, the Smart Synergy Security (3S). The mechanism uses the Set of Experience Knowledge Structure (SOEKS) and the synergy of security methods in different domains to provide the global optimal security strategy. The proposed strategy is taking into account the characteristics of information security (i.e. confidentiality, integrity, availability, controllability, and reviewability)...
-
Structural features responsible for control of the eukaryotic GlcN-6-P synthase activity
PublicationGlucosamine-6-phosphate (GlcN-6-P) synthase is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. As UDP-GlcNAc, the final product of the hexosamine path, constitutes one of the essential substrates for assembly of bacterial and fungal cell walls, the enzyme is an interesting target for antimicrobial therapy.The structure of E. coli enzyme, known since 2001, forms a dimer of two identical...
-
Triangulation-based Constrained Surrogate Modeling of Antennas
PublicationDesign of contemporary antenna structures is heavily based on full-wave electromagnetic (EM) simulation tools. They provide accuracy but are CPU-intensive. Reduction of EM-driven design procedure cost can be achieved by using fast replacement models (surrogates). Unfortunately, standard modeling techniques are unable to ensure sufficient predictive power for real-world antenna structures (multiple parameters, wide parameter ranges,...