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Search results for: DNA TOPOIZOMERAZA I
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Analysis of induction of DNA DSBs on telomeres in A549 cells
Open Research DataData consist of an analysis of DNA DSBs on telomeres. A549 were treated with compounds (TXT4, MTX, DMSO) at IC90 concentration for the indicated time. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss)....
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Phylogenetic trees of genus Oncidium Sw. based on analysis of DNA sequences
Open Research DataGenus Oncidium Sw. is widely regarded as a polyphiletic, and the taxonomic boundaries between him and such genera as Odontoglossum Kunth. or Miltonia Lindley remain blurred. The goal of the study was to determine the phylogenetic relationships within the genus Oncidium s.lato based on the DNA sequences analysis. The correlation between molecular data...
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Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours
Open Research DataThe aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...
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Sequences of large subunit ribosomal RNA gene, partial sequence encoding D1/D2 domain of psychrotolerant pigment-producing yeast-like fungi
Open Research DataDNA fragments encoding D1/D2 domain of large subunit ribosomal RNA of psychrotolerant pigment-producing yeast-like fungi named Red, Pink and Black were PCR amplified using NL1 5’ GCATATCAATAAGCGGAGGAAAAG 3’ and NL4 5’ GGTCCGTGTTTCAAGACGG 3’ primers and sequenced by Sanger method using the same primers.
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Confocal microscopy analysis of DNA DSB in telomerase negative cells after exposure to TXT2 and TXT4
Open Research DataThe data sets contain confocal microscopic images showing the γ-H2AX with TRF2 after treatment of NHBE and U2OS cell lines with TXT2 and TXT4 in equitoxic concentrations. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat...
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Flow cytometry analysis of DNA DSBs in telomerase positive and negative cell lines after treatment with TXT2 and TXT4
Open Research DataFlow cytometry analysis of DNA DSBs in telomerase positive (A549, H460) and negative (NHBE2594, U2OS) cell lines after treatment with equitoxic concentrations of TXT2 and TXT4. MTX and DMSO were used as positive and negative controls, respectively.
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Study of the ability of TXT-compounds to promote telomeric G4 DNA thermal stabilization using FRET melting assay
Open Research DataThe data set contains a DNA melting screen obtained from the FRET melting assay. Thermal stabilities of G-quadruplex structures were analysed in the presence and in absence of ligands. TMPyP4 and MTX were used as references. Measurements were carried out in triplicate using a LightCycler 480 thermocycler (Roche Life Science) with a filter setting of...
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Miedzyborz 2021 - video data I - pedestrian, bicycles, vehicles
Open Research DataMiedzyborz 2021 - video data - pedestrian, bicycles, vehicles
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Krotoszyn 2021 - video data I - pedestrian, bicycles, vehicles
Open Research DataKrotoszyn 2021 - video data - pedestrian, bicycles, vehicles
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state aid for research, development and innovation ( R+D+I)
Open Research DataThe dataset encompasses a choice of important legal acts, a list of selected Polish bibliography, some important individual EC decisions issued on the topic of state aid for research, development, and innovation during the budgetary periods 2007-2013 and 2014-2020. Thanks to that the reader gets the possibility to acquire basic knowledge on the abovementioned...
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Gostyn 2021 - video data I - pedestrian, bicycles, vehicles
Open Research DataGostyn 2021 - video data - pedestrian, bicycles, vehicles
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ArchBGal32cB 441Glu mutein gene analysis dataset
Open Research Data -
Minimum inhibitory concentrations (MICs) determination of selected human topoisomerase II alpha and bacterial DNA gyrase inhibitors against fungal strains
Open Research DataThe datasets contain the results of determining the MIC (Minimal Inhibitory Concentration) value of known compounds* (inhibitors of human topoisomerase II alpha and bacterial DNA gyrase) against C. albicans SC5314, C. glabrata ATCC 90030, C. krusei ATCC 6258 and C. parapsilosis ATCC 22019 and Saccharomyces cerevisiae ATCC 9763 by the modified M27-A3...
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Mechanical studies of poly(lactic acid)-carbon black-nanodiamond composites
Open Research DataThis dataset contains mechanical tests carried out on new 3D printing-dedicated composites with poly-lactic acid (PLA), carbon black (CB) and nanodiamond fillers. Two types of nanodiamonds were studied: detonation nanodiamonds (DND) and boron-doped carbon nanowalls (BCNW). The investigated techniques was dynamic mechanical analysis (DMA). The measurements...
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Case Study NEB Atlas / part I - 3D Models / Brunnshög, Lund
Open Research DataThe data presents the results of work on the analysis of contemporary neighbourhoods. The aim of this part of the research was to create a digital model - a simplified digital twin - for selected parts of housing estates already realised in various cities in Europe. This group presents a model for a fragment of the Brunnshög district in Lund, Sweden....
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Effect of antitumor compounds on the yeast topoisomerase II relaxation activity
Open Research DataThe datasets contain results of antitumor compounds* (known inhibitors of human topoisomerase alpha II) inhibitory activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions,...
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Effect of new bisacridines IKE16, IKE18 and IE10 on the yeast topoisomerase II relaxation activity
Open Research DataThe datasets contain the results of new bisacridines IKE16, IKE18 and IE10 inhibition activity against yeast topoisomerase II. DNA topoisomerases (Topo) are enzymes that catalyze changes in the spatial structure of DNA and play an important role in replication, transcription and recombination. Beyond their normal functions, DNA topo are significant...
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Source code - AI models (MLM1-5 - series I-III - QNM opt)
Open Research DataSource code - AI models (MLM1-5 - series I-III - QNM opt) for the paper "Computational Complexity and Its Influence on Concrete Compressive Strength Prediction Capabilities of Machine Learning Models for Concrete Mix Design Support" accepted for publication.
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Case Study NEB Atlas / part I - 3D Models / King's Cross, London
Open Research DataThe data presents the results of work on the analysis of contemporary neighbourhoods. The aim of this part of the research was to create a digital model - a simplified digital twin - for selected parts of housing estates already realised in various cities in Europe. This group presents a model for a fragment of the King's Cross, London, UK. The students...
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The results of the assessment of the degree of deacetylation, antimicrobial activity and cytotoxicity of chitosan materials
Open Research DataDane prezentują wyniki pomiarowe stopnia deacetylacji 5 komerycjnych chitozanów, które przetwarzane dwiema metodami oceniono pod kątem aktywności przeciwdrobnoustrojowej i cytotoksyczności względem modelowej linii fibroblastów mysich L929. Ocenie porównawczej poddano materiały chitozanowe otrzymywane klasyczną metodą rozpuszczania w roztworze...
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D-loop sequences retrieved from Canis lupus familiaris mitochondrial genome
Open Research DataCanine mitochondrial genome is built of 16727 bp. Non-coding control region (mtCR), called also D-loop, begins with 15458 nucleotide and ends with 16727 nucleotide. The length of this fragment is 1270 bp (Kim et al., 1998). D-loop region is responsible for replication and transcription of mitochondrial DNA. Mutations that occur within it may cause irregularity...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2017, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2017 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2019, two years after the respondents obtained graduate status. The research sample included 1594 respondents. To summarize, in general, respondents...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2018, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2018 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2020, two years after the respondents obtained graduate status. The research sample included 1315 respondents. To summarize, in general, respondents...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2016, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2016 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2018, two years after the respondents obtained graduate status. The research sample included 1947 respondents. To summarize, in general, respondents...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2017, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2017 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2019, two years after the respondents obtained graduate status. The research sample included 1594 respondents. To summarize, in general, respondents...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2016, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2016 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2018, two years after the respondents obtained graduate status. The research sample included 1947 respondents. To summarize, in general, respondents...
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Gdańsk University of Technology graduates’ self-assessment of selected digital competencies by gender – the year 2018, part I
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates' from the year 2018 on their self-assessment of selected digital competencies by gender. The survey was conducted in 2020, two years after the respondents obtained graduate status. The research sample included 1315 respondents. To summarize, in general, respondents...
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XRD, DTA and luminescence measurements of B2O3-Bi2O3-AlF3 glasses doped with Eu3+, Tb3+ and Tm3+ ions
Open Research DataThe DataSet contains the XRD,DTA and luminescence measurements for the B2O3-Bi2O3-AlF3 glass system. Samples were prepared by the conventional melt quenching technique. Starting materials were melted in porcelain crucibles at 950 oC for 20 min. XRD and DTA data were collected for 50B2O3-50Bi2O3,45B2O3-45Bi2O3+10AlF3 and 40B2O3-40Bi2O3+20AlF3 glasses....
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Sequences of internal transcribed spacer 1, 5.8S ribosomal RNA gene and internal transcribed spacer 2 of psychrotolerant pigment-producing yeast-like fungi
Open Research DataDNA encoding ITS1-5.8S-ITS2 fragments of psychrotolerant pigment-producing yeast-like fungi named Red, Pink and Black were PCR amplified using ITS1 5' TCCGTAGGTGAACCTGCGG 3' and ITS4 5’ TCCTCCGCTTATTGATATGC 3’ primers and sequenced by Sanger method using the same primers.
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Cyclic voltammetry curves of the V2O5 nanorods (Na-ion batteries)
Open Research DataThe DataSet contains the next thirty cycles voltammetry curves for the V2O5 nanorods obtained by the sol-gel method. The cyclic voltammetry was measured using the AUTOLAB 302N potentiostat-galvanostat. The measurements were carried out in a voltage range of 2 V to 4 V vs. Na/Na+ at a scan rate of 1 mV/s. As an electrolyte 1M NaPF6 was applied.
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Cyclic voltammetry curves of the V2O5 nanocrystals (Na-ion batteries)
Open Research DataThe DataSet contains the next thirty cycles voltammetry curves for the V2O5 nanocrystals obtained by the sol-gel method. The cyclic voltammetry was measured using the AUTOLAB 302N potentiostat-galvanostat. The measurements were carried out in a voltage range of 2 V to 4 V vs. Na/Na+ at a scan rate of 1 mV/s. As an electrolyte 1M NaPF6 was applied.
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Cycling performances of the V2O5 nanostructures as cathode material in Na-ion batteries
Open Research DataThe DataSet contains the next one hundred galvanostatic charge/discharge curves of the V2O5 nanostructures with different morphology obtained by the sol-gel method. The battery tests of the samples were performed using the Atlas-Sollich 0961 (Atlas-Sollich, Poland) with C/5 current densities in the voltage range between 2.0 V and 4.0 V vs. Li/Li+. Here...
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TRNA-Leu (UUR) gene haplotypes observed in canine mammary gland tumours and its deleterious effect assessment according to the comparative analysis with TRNL1 human gene
Open Research DataThe aetiology and pathogenesis of many canine tumours are likely to be similar to cancers found in humans. This study aimed to present a plausible link between changes in tRNA-Leu (UUR) gene and the carcinogenesis process in dogs with mammary gland tumours. The whole mitochondrial DNA (mtDNA) isolated from blood and tumour tissues of 13 dogs with malig-nant...
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Concrete temperature measurements of cubic specimens cured under isothermal and semi-adiabatic conditions
Open Research DataThe DataSet contains temperature measurements of concrete cubes (150 x 150 x 150 mm) cured under isothermal and semi-adiabatic conditions. The specimens were moulded from six types of concrete mixtures produced in the laboratory conditions. Mix #1: Portland cement CEM I 42.5R and gravel aggregate, mix #2: CEM I 42.5R and basalt aggregate, mix#3: Portland-composite...
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Identification and cloning of C. albicans SC5314 genes encoding L-methionine biosynthetic pathway enzymes.
Open Research DataEnzymes of fungal L-methionine biosynthetic pathway: homoserine O-acetyltransferase (Met2p), O-acetylhomoserine sulfhydrylase (Met15p) and cystathionine-γ-synthase (Str2p) could be exploited as molecular targets for antifungal chemotherapy. The goal of the study was to identify and clone genes encoding mentioned above enzymes. MET2, MET15 and STR2 genes...
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Description of symmetrical prolate ellipsoid (sphere) magnetic signature parameters-Be = 50 mT, I = 70 deg, z = -10 m, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid (sphere) magnetic signature parameters-Be = 50 mT, I = 70 deg, z = -100 m, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid (sphere) magnetic signature parameters-Be = 50 mT, I = 70 deg, z = -50 m, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid (sphere) magnetic signature parameters-Be = 50 mT, I = 70 deg, z = -10 m, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid (sphere) magnetic signature parameters-Be = 50 mT, I = 70 deg, z = -20 m, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 50 m, q = 80 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 100 m, q = 90 deg, j = 135 deg, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 10 m, q = 100 deg, j = 45 deg, a =4 m, e = 4, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 20 m, q = 100 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 200 m, q = 90 deg, j = 45 deg, a =4 m, e = 1, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 50 m, q = 100 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 200 m, q = 80 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 100 m, q = 90 deg, j = 45 deg, a =4 m, e = 4, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters -Be = 50 mT, I = 70 deg, z = 10 m, q = 80 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.
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Description of symmetrical prolate ellipsoid magnetic signature parameters-Be = 50 mT, I = 70 deg, z = 100 m, q = 100 deg, j = 45 deg, a =4 m, e = 8, mr = 100
Open Research DataThe Earth magnetic field (Fig.1): BE – total magnetic flux density, BEx – x component of the Earth magnetic flux density, BEy = 0 y component of the Earth magnetic flux density, BEz – z component of the Earth magnetic flux density, I – the inclination of the Earth magnetic field.