Filters
total: 3400
filtered: 2844
-
Catalog
Chosen catalog filters
displaying 1000 best results Help
Search results for: folded proteins
-
Ocena niezawodności spawanych złączy różnoimiennych = Reliability estimation of the dissimilar welded joints
PublicationOceniano niezawodność różnoimiennych złączy spawanych stali 10H2M ze stałą węglową oraz stalą chromowo-niklową. Zaproponowano metodę oceny niezawodności złączy wykorzystującą wskaźniki maksymalnej twardości w złączu oraz plastyczności struktury.
-
Effect of native air-formed oxidation on the corrosion behavior of AA7075 aluminum alloys
PublicationThe microstructure of aluminum alloys plays a key role in their corrosion resistance. In particular, the presence of intermetallic precipitates differing in the potential from the alloy matrix induces local corrosion. The study presents the effect of native air-formed oxidation on the corrosion behavior of AA 7075 aluminum alloy. Various microscopic and spectroscopic techniques were used to examine the changes occurring in the...
-
Vibration surveillance for efficient milling of flexible details fixed in adjustable stiffness holder
PublicationThe paper presents the results of research related to the possibility of using an intelligent workpiece holder with adjustable stiffness, during end milling process. Machining a one side supported flexible workpiece will be performed with constant spindle speed and feed speed. In order to avoid hazardous vibration, stiffness of the especially designed spring (mounted in a workpiece holder) will be modified off-line. In order to...
-
Influence of silver nanoparticles addition on antibacterial properties of PEO coatings formed on magnesium
PublicationMagnesium is a biodegradable material and thus could be a choice for bone fixation devices and implants with a specific purpose. This study aims to enhance the anti-corrosive, biocompatible, and antibacterial properties on magnesium-based materials through ceramic coatings formation. To achieve this the silicate-based electrolyte was used to create of Plasma Electrolytic Oxidation (PEO) coatings. During investigation the bioactive...
-
Model tests of cast-in-place piles formed by using different types of auger
PublicationModel tests are still a popular research tool used to observe and determine the mechanisms of pile-soil interaction. Due to the significant scale effect, the results of model tests performed in the 1g system can only be analysed from the qualitative side. This article describes and presents the results of 1g pile model tests carried out for comparative purposes. There were tested the effectiveness and efficiency of various types...
-
Effects of preheating on laser beam–welded NSSC 2120 lean duplex steel
PublicationDuplex stainless steels show sustainable alternative for the conventional austenitic grades, with higher strength, higher resistance against stress corrosion cracking, and lower purchase cost. Thus, duplex stainless steel gains more attention in construction, oil and gas, and chemical industries. Among duplex stainless steels, low nickel and low molybdenum alloyed lean duplex stainless steel are a cost-efective substitution of...
-
Experimental determination of dynamic properties of cylindrical steel tank model filled with liquid
PublicationIn technical branches, such as chemical or petroleum industries, cylindrical steel tanks are essential structures used for storage of liquid products. Any failure might have disastrous consequences, therefore their safety and reliability is essential. The aim of the present paper is to show the results of the experimental study which has been conducted on a scaled model of a real tank used in Poland. The investigation was carried...
-
Wear and corrosion characteristics of the layers type (mn-p) formed on aluminium alloys
Publicationopisano multipleksową metodę wytwarzania warstw zawierających mangan i fosfor (mn-p) na stopach aluminium. przedstawiono wyniki badań mikrostruktury, właściwości tribologicznych i korozyjnych tych warstw. stwierdzono obecność tlenku manganu i fosforku manganu w wytworzonych warstwach oraz ich wysoką twardość, rzędu 1272 hv0,02. warstwy typu (mn-p) zmniejszają podatność stopu alsi13mg1cuni na korozję w 0,01 mh2so4.
-
Tests for lapping of flat surfaces of ceramic elements with forced dosing of abrasive slurry
PublicationPrzedstawiono zagadnienia dotyczące systemu wymuszonego dawkowania zawiesiny ściernej w docieraniu jednotarczowym powierzchni płaskich. Opisano zalety takiego systemu dozowania płynnej zawiesiny ściernej. Omówiono wybrane wyniki badań docierania elementów z ceramiki technicznej. Analizowano wpływ podstawowych warunków dawkowania zawiesiny na ubytek liniowy próbek.
-
Weldability of Underwater Wet-Welded HSLA Steel: Effects of Electrode Hydrophobic Coatings
PublicationThe paper presents the effects of waterproof coatings use to cover electrodes on the weldability of high-strength, low-alloy (HSLA) steel in water. With the aim of improving the weldability of S460N HSLA steel in water, modifications of welding filler material were chosen. The surfaces of electrodes were covered by different hydrophobic substances. The aim of the controlled thermal severity (CTS) test was to check the influence...
-
Properties of Barium Cerate Thin Films Formed Using E-Beam Deposition
PublicationThis article focuses on the properties of the BaCeO3 thin films formed by electron-beam vapor deposition and investigates the formation of barium cerates on supports with different thermal expansion coefficients (Stainless Steel, Invar, Glass Sealing, and Inconel substrates) and the influence of the technological parameters on the properties of the formed thin films with an emphasis on the stability of the films. Morphology and...
-
Effect of Processing Parameters on Strength and Corrosion Resistance of Friction Stir-Welded AA6082
PublicationThe friction stir welding method is increasingly attracting interest in the railway sector due to its environmental friendliness, low cost, and ease of producing high-quality joints. Using aluminum alloys reduces the weight of structures, increasing their payload and reducing fuel consumption and running costs. The following paper presents studies on the microstructure, strength, and corrosion resistance of AA6082 aluminum alloy...
-
Effect of aeration of antibiotic-loaded bone cement on its properties and bactericidal effectiveness
PublicationBACKGROUND: Antibiotic-loaded bone cements are now widely used in medicine. They are able to locally deliver antibiotic particles and they allow treat or protect against infection. It is assumed that the bactericidal effectiveness of bioactive bone cements depend on the parameters of its production. Hence, the aim of this study was to check the effect of aeration of bone cement before mixing the components on its properties as...
-
Experimental investigation of forced convection of water/EGAl2O3 nanofluids inside horizontal tube
PublicationIn this paper, forced convection of water/EG-Al2O3 nanofluids inside horizontal stainless steel tube is studied experimentally. As base fluid served water/EG mixture of two ratios (60:50 and 50:50). Nanoparticle mass concentrations was 0.1% or and 1%. Transition and turbulent flow regimes were tested. Average heat transfer coefficient and pressure drop values were determined for nanofluids and compared to base fluids. Deterioration...
-
Rotational Molding of Linear Low-Density Polyethylene Composites Filled with Wheat Bran
PublicationApplication of lignocellulosic fillers in the manufacturing of wood polymer composites (WPCs) is a very popular trend of research, however it is still rarely observed in the case of rotational molding. The present study aimed to analyze the impact of wheat bran content (from 2.5 wt.% to 20 wt.%) on the performance of rotationally-molded composites based on a linear low-density polyethylene (LLDPE) matrix. Microscopic structure...
-
The Impact of Sloshing Liquids on Ship Stability for Various Dimensions of Partly Filled Tanks
PublicationLiquid sloshing phenomenon taking place in partly filled ships' tanks directly affects the stability of a vessel. However, only static calculations are carried out onboard ships nowadays and static transfer of liquid weight is taken into account in the course of routine stability calculation. The paper is focused on a dynamic heeling moment due to liquid sloshing in tanks onboard ships. A number of numerical simulations of liquid...
-
An investigation on residual stress and fatigue life assessment of T-shape welded joints
PublicationThis paper aims to quantitatively evaluate the residual stress and fatigue life of T-type welded joints with a multi-pass weld in different direction. The main research objectives of the experimental test were to test the residual stress by changing direction along with multiple wielding passes and determine the fatigue life of the welded joints. The result shows that compressive residual stress increases in the sample gradually...
-
Impact of Temperature and Nanoparticle Concentration on Turbulent Forced Convective Heat Transfer of Nanofluids
PublicationTheoretical analysis of the influence of nanoparticles and temperature on the average Nusselt (Nu) number and the average heat transfer coefficient (HTC) during the turbulent flow of nanofluid in a horizontal, round tube was carried out. The Nu number is a function of the Reynolds (Re) number and the Prandtl (Pr) number, which in turn are functions of the thermophysical properties of the liquid and the flow conditions. On the other...
-
A Compact and Lightweight Microwave Tilt Sensor Based on an SRR-Loaded Microstrip Line
PublicationIn this paper, the symmetry property of split ring resonators (SRRs) is exploited to develop a tilt sensor. The sensor is composed of an SRR-loaded microstrip line operating at microwave frequencies. It is shown that the depth of notch in the reflection characteristic of the microstrip is a function of the tilt angle of the SRR. Thus, it can be used for sensing inclination. The sensor benefits from very compact size and light weight....
-
Effect of Arc Strikes on High Strength Low Alloy Steels Welded by SMAW
PublicationWet welding with covered electrodes (Shielded Metal Arc Welding – SMAW) is the most commonly used method of carrying out welding repair works in a water environment. Limited visibility and the inability to move freely under water result in an increased risk of formation of welding imperfections such as lack of fusion, lack of penetration and arc strikes. The work focused on changes in the properties and structure of steel subjected...
-
Electromagnetic forced vibrations of composite nanoplates using nonlocal strain gradient theory
PublicationThis article is intended to analyze forced vibrations of a piezoelectric-piezomagnetic ceramic nanoplate by a new refined shear deformation plate theory in conjunction with higher-order nonlocal strain gradient theory. As both stress nonlocality and strain gradient size-dependent effects are taken into account using the higher-order nonlocal strain gradient theory, the governing equations of the composite nanoplate are formulated....
-
Experimental Investigations of Forced Convection of Nanofluids in Smooth, Horizontal, Round Tubes: A Review
PublicationA comprehensive review of published works dealing with experimental studies of forced convection heat transfer of nanofluids is presented. The survey is limited to straight, smooth, and round tubes. Moreover, only mono nanofluids exhibiting Newtonian behaviour are considered. Works on experimental research of forced convection in tubes are presented in a chronological order in the first part of the article. In this part, attention...
-
Comparison of mass spectrometry data and bioinformatics predictions to assess the bona fide localization of proteins identified in cell wall proteomics studies
Publication -
Ergodicity and model quality in template-restrained canonical and temperature/Hamiltonian replica exchange coarse-grained molecular dynamics simulations of proteins
Publication -
Development of Physics-Based Energy Functions that Predict Medium-Resolution Structures for Proteins of the α, β, and α/β Structural Classes
Publication -
Optimization of the UNRES Force Field by Hierarchical Design of the Potential-Energy Landscape. 2. Off-Lattice Tests of the Method with Single Proteins
Publication -
Identification and characterization of single-stranded-DNA-binding proteins from Thermus thermophilus and Thermus aquaticus - new arrangement of binding domains
PublicationOkreślono molekularne właściwości białek SSB-podobnych z Thermus thermophi-lus i T. aquaticus. Zbadano aktywność białek oraz termostabilność. Ponadto, dowiedziono homodimeryczność obu białek i ustalono minimalną sekwencję wiążącą ssDNA.
-
Evaluation of long‑term immunity and protection against T. gondii after immunization with multivalent recombinant chimeric T. gondii proteins
PublicationToxoplasmosis caused by the opportunistic, cosmopolitan protozoan Toxoplasma gondii is one of the most common parasitoses in the world. Although it may prove dangerous or even fatal for immunocompromised individuals, immunoprophylaxis for humans is still nonexistent. Thus, the aim of the current work was to assess the ability of two immunogenic recombinant chimeric T. gondii proteins, SAG2-GRA1-ROP1 (SGR) and SAG1-MIC1-MAG1-GRA2...
-
Organizational Forms and Management for the Building of Creative Capital of Older People
Publication -
Shared Psychotic Disorder: A case of “Folie a deux” with a delusion of pregnancy
Publication -
Needs of Older People Attending Day Care Centres in Poland
Publication -
Cross-talk Between the Heart and Arteries in Older 65+ Adults
PublicationRegulatory synchronization between the heart and the arterial walls is essential for optimal blood delivery to tissues. We investigated functional coherence between heart rhythm and aortic wall compliance in 30 volunteers aged 65 – 74. ECG and carotid and iliac pulse-wave were recorded and digitized at 2 kHz. Carotid-femoral pulse-wave transit time (cfTT) which reflex aortic compliance was assessed using the intersecting tangent...
-
Investigation of interaction between xanthene dye rhodamine B and metagenomic-derivated methylthioadenosine phosphorylase RSFP
PublicationIn the previous study we found that the expression of the metagenomic - derived methylthioadenosine phosphorylase gene (rsfp) in E. coli cells and the presence of rhodamine B in the growth medium were crucial for the pink fluorescence of one E. coli colony from Antarctic soil metagenomic library (Cieśliński et al., 2009). In this study, rsfp gene expression was induced by an arabinose promoter in an LMG194 E. coli strain and the...
-
The structurally similar TRFH domain of TRF1 and TRF2 dimers shows distinct behaviour towards TIN2
PublicationThe telomere repeat binding-factor 1 and 2 (TRF1 and TRF2) proteins of the shelterin complex bind to duplex telomeric DNA as homodimers, and the homodimerization is mediated by their TRFH (TRF-homology) domains. We performed molecular dynamic (MD) simulations of the dimer forms of TRF1TRFH and TRF2TRFH in the presence/absence of the TIN2TBM (TIN2, TRF-interacting nuclear protein 2, TBM, TRF-binding motif) peptide. The MD results...
-
Structural and dynamic changes adopted by EmrE, multidrug transporter protein—Studies by molecular dynamics simulation
PublicationEmrE protein transports positively charged aromatic drugs (xenobiotics) in exchange for two protons and thus provides bacteria resistance to variety of drugs. In order to understand how this protein may recognize ligands, the monomer and asymmetric apo-form of the EmrE dimer embedded in a heterogeneous phospholipid (POPE + POPG) membrane were studied by molecular dynamics simulations. Dimer is regarded as a functional form of the...
-
Role of the disulfide bond in stabilizing and folding of the fimbrial protein DraE from uropathogenic Escherichia coli
PublicationDr fimbriae are homopolymeric adhesive organelles of uropathogenic Escherichia coli composed of DraE subunits, responsible for the attachment to host cells. These structures are characterized by enormously high stability resulting from the structural properties of an Ig-like fold of DraE. One feature of DraE and other fimbrial subunits that makes them peculiar among Ig-like domain-containing proteins is a conserved disulfide bond...
-
Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells
Publication -
Structural and dynamic insights on the EmrE protein with TPP+ and related substrates through molecular dynamics simulations
PublicationEmrE is a bacterial transporter protein that forms an anti-parallel homodimer with four transmembrane helices in each monomer. EmrE transports positively charged aromatic compounds, such as TPP+ and its derivatives. We performed molecular dynamics (MD) simulations of EmrE in complex with TPP+, MeTPP+, and MBTPP+ embedded in a membrane. The detailed molecular properties and interactions were analysed for all EmrE-ligand complexes....
-
The Escherichia coli RNA polymerase alpha subunit and transcriptional activation by bacteriophage lambda CII protein.
Publication -
Mitogen activated protein kinase 4 (MPK4) influences growth in Populus tremula L.×tremuloides
Publication -
Rapeseed Meal Waste Biomass as Single-Cell Protein Substrate for Nutritionally-Enhanced Feed Component
Publication -
CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures
Publication -
Towards Temperature Dependent Coarse-grained Potential of Side-chain Interactions for Protein Folding Simulations
Publication -
UNRES server for physics-based coarse-grained simulations and prediction of protein structure, dynamics and thermodynamics
Publication -
Methodology of Selecting the Optimal Receptor to Create an Electrochemical Immunosensor for Equine Arteritis Virus Protein Detection
PublicationThe study reports a methodology of selecting the optimal receptor to create an electrochemical immunosensor for equine arteritis virus (EAV) protein detection. The detection was based on antigen recognition by antibodies immobilized on gold electrodes. Modification steps were controlled by electrochemical impedance spectroscopy and cyclic voltammetry measurements. In order to obtain the impedance immunosensor with the best parameters,...
-
A cryptic ribosome binding site, false signals in reporter systems and avoidance of protein translation chaos
PublicationThe expression of reporter gene may be induced by activation of cryptic signalling sequences, as we found while constructing the mutS-lacZ fusion gene. We cloned the Escherichia coli lacZ gene encoding beta-galactosidase into a plasmid vector carrying the Thermus thermophilus mutS gene. The clones expected to produce beta-galactosidase as the C-terminal fusion were selected for the complementation of beta-galactosidase activity...
-
Comparison of Antioxidant Activity of Protein Isolates Derived from Selected Dry-Cured Meat Products
Publication -
E2/E3‐independent ubiquitin‐like protein conjugation by Urm1 is directly coupled to cysteine persulfidation
Publication -
Post mortem changes in M. iliotibialis lateralis muscle protein profile of emu (Dromaius novaehollandiae)
Publication -
Excessive amount of lactose in the diet of two-week-old calves induces urinary protein changes
Publication