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Search results for: TARGETED SAMPLING
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Multi-objective weather routing of sailing vessels
PublicationThe paper presents a multi-objective deterministic method of weather routing for sailing vessels. Depending on a particular purpose of sailboat weather routing, the presented method makes it possible to customize the criteria and constraints so as to fit a particular user’s needs. Apart from a typical shortest time criterion, safety and comfort can also be taken into account. Additionally, the method supports dynamic weather data:...
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METHOD OF ROUTING SHIPS SAILING IN DEDICATED ENVIRONMENT
PublicationThe method for determining the suboptimal route of sailing vessels operating in a restricted area of the sea are proposed in the paper. The dynamics of the environment including weather conditions and speed characteristics of ships sailing are considered. As optimiza-tion criterion, measure sailing time T, and the number of maneuvers performed ω, are taken into account. An heuristic algorithm, and the appropriate application routing...
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Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension
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Novel NK1R-Targeted 68Ga-/177Lu-Radioconjugates with Potential Application against Glioblastoma Multiforme: Preliminary Exploration of Structure–Activity Relationships
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Error analysis of calculating average d-q current components using Regular Sampling and Park transformation in FOC drives
PublicationIn electric drives using voltage source inverters, motor currents contain ripple component resulting from pulse-width modulated (PWM) voltage. The frequency range of the ripples is much higher than the bandwidth of current control. Therefore the control is performed on the basis of a fundamental current component, i.e. average value with the averaging time being the PWM period. In majority of cases the average current is measured...
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Application of passive sampling technique for monitoring of BTEX concentration in urban air: Field comparison of different types of passive samplers
PublicationW efekcie przeprowadzonych badań potwierdzono przydatności techniki dozymetrii pasywnej wykorzystywanej na etapie izolacji i wzbogacania analitów do uzyskania informacji o poziomie stężeń zanieczyszczeń z grupy BTEX w powietrzu atmosferycznym na terenie aglomeracji Trójmiejskiej. Dodatkowo, porównano wyniki oznaczeń uzyskanych z wykorzystaniem dwóch typów dozymetrów pasywnych.
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Doppler estimation method for moving target location
PublicationArtykuł opisuje nowy algorytm lokalizacji obiektów ruchomych bazujących na analizie odchyłek dopplerowskich sygnałów odebranych z sieci hydrofonów rozmieszczonych równomiernie w obserwowanym akwenie. Źródłem analizowanych sygnałów są fale ciągłe o niskim natężeniu odbite od obiektu ruchomego. W artykule została przedstawiona postać algorytmu oraz wyniki symulacji komputerowych.
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The Role of FLT3 Kinase as an AML Therapy Target
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Feasibility study of a novel hot stamping process for Ti6Al4V alloy
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CPTU/DMT control of heavy tamping compaction of sands
PublicationHeavy tamping compaction method in cohesionless alluvial soil was evaluated with CPTU and DMT tests. Some examples of interpretation of soundings in pre-treated and compacted sands are given. The compaction work was performed in two stages. Compaction control was performed after each stage of tamping. Additional tests were performed two weeks after the compaction works completion to study the set-up effect. While typical increase...
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Active Damping of Impulse-Excited Flexible Plate Vibration
PublicationArtykuł prezentuje metodę aktywnego tłumienia drgań podatnej płytki wzbudzanych impulsowo. Układ sterowania składa się z aktywych wzbudników piezoelektrycznych przymocowanych do przedmiotu. Efektywnośc metody została potwierdzona badaniami eksperymentalnymi.
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Propagation of elestic waves in beams including damping effects.
PublicationW pracy przedstawiono wyniki analizy propagacji fali sprężystej w belce z tłumieniem wiskotycznym.
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Non-linear model of high damping rubber bearing.
PublicationCelem artykułu jest analiza modelu łożyska wykonanego z wysokotłumiącej gumy, które wykorzystywane są do posadowienia konstrukcji budowlanych na terenach sejsmicznych. Model umożliwia numeryczną symulację pracy urządzenia pod zadanym obciążeniem i w danych warunkach termiczno-wilgotnościowych. Wyniki analizy pokazują, iż proponowany model umożliwia symulację zachowania się łożyska w szerokim zakresie odkształceń.
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Investigating lubricants behaviour in microgravity for vibration damping purposes
PublicationVibration is one of the harshest environments an object is exposed to during and after launch into space on a launch vehicle. Such vibrations should be damped to avoid destruction of the spacecraft or its elements. Currently, active and material damping is used. A possibility of using lubrication as the damping factor is suggested by some research. MoS2 is a typical solid lubricant used in space applications. Its properties vary...
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Parallel implementation of a Sailing Assistance Application in a Cloud Environment
PublicationSailboat weather routing is a highly complex problem in terms of both the computational time and memory. The reason for this is a large search resulting in a multitude of possible routes and a variety of user preferences. Analysing all possible routes is only feasible for small sailing regions, low-resolution maps, or sailboat movements on a grid. Therefore, various heuristic approaches are often applied, which can find solutions...
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The Doppler effect in a bistatic system for determining the position of moving targets
PublicationThe article presents the theoretical analysis and the results of numerical calculations of the Doppler effect it occurs in a system designed to determine the position and speed of a moving target. The transmitter is the source of the signal and it emits a sinusoidal, acoustic and continuous wave. Signal reflected off a moving target is received by four hydrophones. Based on the signals, four Doppler shifts are determined and inserted...
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Optimization of multiple model neural tracking filter for marine targets
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Flavonoid biosynthetic pathways in plants: Versatile targets for metabolic engineering
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New Peptide Based Fluconazole Conjugates with Expanded Molecular Targets
PublicationInfections of Candida spp. etiology are frequently treated with azole drugs. Among azoles, the most widely used in the clinical scenario remains fluconazole (FLC). Promising results in treatment of dangerous, systemic Candida infections demonstrate the advantages of combined therapies carried out with combinations of at least two different antifungal agents. Here, we report five conjugates composed of covalently linked FLC and...
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Molecular targets for antifungals in amino acid and protein biosynthetic pathways
PublicationFungi cause death of over 1.5 million people every year, while cutaneous mycoses are among the most common infections in the world. Mycoses vary greatly in severity, there are long-term skin (ringworm), nail or hair infections (tinea capitis), recurrent like vaginal candidiasis or severe, life-threatening systemic, multiorgan infections. In the last few years, increasing importance is attached to the health and economic problems...
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Human red blood cells targeted metabolome analysis of glycolysis cycle metabolites by capillary electrophoresis using an indirect photometric detection method
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Molecularly targeted nanoparticles: an emerging tool for evaluation of expression of the receptor for advanced glycation end products in a murine model of peripheral artery disease
PublicationAbstract Background: Molecular imaging with molecularly targeted probes is a powerful tool for studying the spatio-temporal interactions between complex biological processes. The pivotal role of the receptor for advanced glycation end products (RAGE) in numerous pathological processes, aroused the demand for RAGE targeted imaging in various diseases. In the study, we evaluated the use of a diagnostic imaging agent for RAGE quantification...
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Diagnostics of the tram track shape with the use of the global positioning satellite systems (GPS/Glonass) measurements with a 20 Hz frequency sampling
PublicationSatellite geodetic measurements used in the diagnosis of railway tracks require professional receivers and a very high frequency rate of data processing. It stems from a significant speed (10 km/h) kinematic measurements carried out during the passage of a measuring platform. The survey results (positions) of deformed railroad track have waveforms nature requiring additional processing methods and approximations. Due to the announcement...
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Weighted Ensemble with one-class Classification and Over-sampling and Instance selection (WECOI): An approach for learning from imbalanced data streams
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Pobieranie próbek opadów atmosferycznych do analizy. Opis stosowanych próbników. Sampling of atmospheric precipitation for the analysis. Description applied samplers
PublicationW pracy przedstawiono opis podstawowych typów próbników wykorzystywanych do pobierania próbek opadów atmosferycznych (woda deszczowa, wody spływne, mgła) oraz tok postępowania analitycznego z pobranymi próbkami w celu oznaczenia szerokiego spektrum składników śladowych.
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Unconventional and user-friendly sampling techniques of semi-volatile organic compounds present in an indoor environment: An approach to human exposure assessment
PublicationThe commonly applied solutions used to assess the potential risk of human exposure to semi-volatile organic compounds (SVOCs) are based on the investigation of biological samples collected in an invasive or non-invasive manner. For SVOCs, which are typically introduced to humans through the respiratory system, dermal adsorption, or digestive system, sampling solutions generally used in the indoor environments are classified as...
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Evolution of Animats Following a Moving Target in an Artificial Ecosystem
PublicationMany biological animals, even microscopically small, are able to track moving sources of food. In this paper, we investigate the emergence of such behavior in artificial animals (animats) in a 2-dimensional simulated liquid environment. These "predators" are controlled by evolving artificial gene regulatory networks encoded in linear genomes. The fate of the predators is determined only by their ability to gather food and reproduce—no...
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Neural Manoeuvre Detection of the Tracked Target in ARPA Systems
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Bearing errors passive sonar stationary target location
PublicationPrzedstawiono metodę wyznaczania współrzędnych nieruchomego celu na podstawie namiarów wykonywanych w sonarze pasywnym. Określono wymagania odnośnie ruchu sonaru, przy których błędy wyznaczania współrzędnych są minimalne. Podano zależności umożliwiające analityczne wyznaczanie błędów współrzędnych. Poprawność wyników analizy potwierdzono eksperymentami numerycznymi.
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On a threshold induced bias in fish target strength estimation.
PublicationPrzedstawiono statystyczny opis zjawiska wpływu progu rejestracji ech od ryb na estymatę siły celu ryb. Pokazano sposób korekcji wykorzystujący zależności pomiędzy funkcjami rozkładu prawdopodobieństwa poziomu echa i charakterystyki wiązki. Przedstawiono wyniki symulacji.
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Targed tracking with adaptive fusionof multiple sensor measurements.
PublicationW pracy przedstawiono metodę adaptacyjnej selekcji pomiarów z wielu radarów wykorzystywanych w procesie integracji pomiarów dla śledzenia obserwowanego obiektu. W przypadku dużego zróżnicowania dokładności pomiarów pochodzących z różnych radarów, rezultaty integracji pomiarów nie różnią się znacząco od wyników śledzenia opartego na pomiarach z najbardziej dokładnego źródła.
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Telomerase inhibition - unfulfilled hopes in the perfect molecular target
PublicationTelomerase plays a pivotal role in cell proliferation, homeostasis, and neoplastic transformation, making it a promising molecular target for cancer chemotherapy. Of note, although hTERT has been explored thoroughly as a target, none of the promising molecules has been approved as a drug until now. The subject of research conducted as part of my doctoral dissertation is explaining the cellular and molecular mechanism of action...
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Characterisation of the interfacial heat transfer coefficient in hot stamping of titanium alloys
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Nonlinear rate dependent model of high damping rubber bearing.
PublicationCelem artykułu jest analiza nieliniowego modelu łożyska wykonanego z wysokotłumiącej gumy, który symuluje pracę urządzenia pod zadanym obciążeniem. Parametry modelu dobrane są na podstawie wyników badań eksperymentalnych. Wyniki pracy pokazują, iż analizowany model umożliwia symulację zachowania się łożyska w szerokim zakresie odkształceń
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SAILING ROUTE PLANNING METHOD CONSIDERING VARIOUS USER CATEGORIES
PublicationThe article describes the methodology related to determining the multi-criteria routes for sailing ships. Details of sea area discretisation and discretisation of the description of the sailing vessel properties and manoeuvring principles are shown. User requirements were specified (for five different categories of users) and on this basis the criteria for selecting the most suitable shipping route were formulated. The presented...
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OPTIMISING RIG DESIGN FOR SAILING YACHTS WITH EVOLUTIONARY MULTIOBJECTIVE ALGORITHM
PublicationThe paper presents a framework for optimising a sailing yacht rig using Multi-objective Evolutionary Algorithms and for filtering obtained solutions by means of a Multi-criteria Decision Making method. A Bermuda sloop with discontinuous rig is taken under consideration as a model rig configuration. It has been decomposed into its elements and described by a set of control parameters to form a responsive model which can be used...
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Transient response of oscillated carbon nanotubes with an internal and external damping
PublicationThe present works aims at modeling a viscoelastic nanobeam with simple boundary conditions at the two ends with the introduction of the Kelvin-Voigt viscoelasticity in a nonlocal strain gradient theory. The nanobeam lies on the visco-Pasternak matrix in which three characteristic parameters have a prominent role. A refined Timoshenko beam theory is here applied, which is only based on one unknown variable, in accordance with the...
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Problems with modelling the strength properties of sailing vessels rigging ropes
PublicationThis article presents the basic parameters of soft ropes: natural fibre ropes, soft wire ropes and synthetic fibre ropes used for running rigging. There are only several materials still used for the production of natural fibre ropes, including cotton, jute, hemp, sisal and manila hemp. The most commonly used soft wire ropes are twisted pair ropes; for smaller diameters there is a 6x19M - FC rope and for larger diameters – 6x37M...
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Zastosowanie techniki dozymetrii pasywnej do oceny jakości powietrza wewnętrznego. Application of passive sampling technique for assessment of indoor air quality
PublicationJakość powietrza wewnętrznego jest istotnym parametrem wpływającym na dobre samopoczucie i zdrowie człowieka. Kluczowego znaczenia nabiera więc jego nieustanna kontrola i oznaczanie zawartości zanieczyszczeń, które występują w nim na bardzo niskich poziomach stężeń. Do pomiarów jakości powietrza wewnętrznego często wykorzystywana jest (znana od ponad pół wieku) technika dozymetrii pasywnej. W literaturze nadal pojawiają się doniesienia...
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Multisensor Tracking of Marine Targets - Decentralized Fusion of Kalman and Neural Filters
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The Extracellular Bacterial HtrA Proteins as Potential Therapeutic Targets and Vaccine Candidates
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Track-to-track fusion in tracking of multiple targets in clutter - a comparative study.
PublicationPrzedstawiono i porównano algorytmy rozproszone wyznaczania trajektorii obiektów dynamicznych na podstawie danych z wielu źródeł. Rozważono przypadek, w którym dane dotyczące pozycji obiektów są zakłócone przez dodatkowe fałszywe wykrycia niezwiązane z obserwowanymi obiektami. Algorytmy rozproszone i centralne to dwie podstawowe klasy algorytmów służące do wyznaczania trajektorii obiektów dynamicznych na podstawie danych z wielu...
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Phoenixin as a New Target in the Development of Strategies for Endometriosis Diagnosis and Treatment
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On Some Aspects of Fish Target Strength Estimation in Shallow Waters
PublicationThe theory of acoustic surveys for determining fish abundance are well established in fishery acoustics. The origins of the estimation are related to overcoming the problem of unknown position of target in the beam using statistical inversion. Although recently researchers use more sophisticated echosounders that provides more informative data allowing for direct solution it is known that the results are biased due to not ideally...
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Receiver of Doppler multistatic system for moving target detection and tracking
PublicationThe article presents a method for solving major structural problems that occur in the receiver used in the multistatic Doppler system, aimed at determination of the trajectory and velocity of a moving target. In the system two transmitters emit acoustic continuous sinusoidal waves at different frequencies. The signals, scattered from a moving target are received by four hydrophones. Beside of the echoes, much larger signals coming...
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Oxidative Stress as a Possible Target in the Treatment of Toxoplasmosis: Perspectives and Ambiguities
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CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma
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Fish target strength estimation using multiple echo statistics
PublicationW pracy przedstawiono sposób określania statystycznych właściwości charakterystyki wiązki systemu hydroakustycznego z uwzględnieniem możliwości pojawienia się echo wielokrotnych od jednej ryby. Przedstawiono modele obejmujące dwa teoretyczne przypadki związane z wzajemnym ruchem statku i pojedynczej ryby i pokazano, że posiadają one zbliżone właściwości statystyczne. Rozważania teoretyczne potwierdzone są analizą przykładowych...
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Membrane in tandem with a helical sorbent trap as continuous sampling technique of the polyvinyl chloride thermo-oxidative degradation products for their on-line gas chromatographic monitoring
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Development of chromatographic and mass spectrometry conditions for untargeted lipidomic analysis of human breast milk
PublicationHuman breast milk (HBM) is a complex biofluid containing components which are essential for the proper growth of the newborn (for example nutrients such as carbohydrates, proteins, lipids) and also bioactive substances. According to the literature, most of studies involving HBM nutrients investigations focused essentially on the determination of proteins. The molecular composition of lipids in HBM is not well known as the protein...