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Telomerase inhibition - unfulfilled hopes in the perfect molecular target
PublicationTelomerase plays a pivotal role in cell proliferation, homeostasis, and neoplastic transformation, making it a promising molecular target for cancer chemotherapy. Of note, although hTERT has been explored thoroughly as a target, none of the promising molecules has been approved as a drug until now. The subject of research conducted as part of my doctoral dissertation is explaining the cellular and molecular mechanism of action...
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A review on analytical models of brushless permanent magnet machines
PublicationThis study provides an in-depth investigation of the use of analytical and numerical methods in analyzing electrical machines. Although numerical models such as the finite-element method (FEM) can handle complex geometries and saturation effects, they have significant computational burdens, are time-consuming, and are inflexible when it comes to changing machine geometries or input values. Analytical models based on magnetic equivalent...
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A Survey of Fast-Recovery Mechanisms in Packet-Switched Networks
PublicationIn order to meet their stringent dependability requirements, most modern packet-switched communication networks support fast-recovery mechanisms in the data plane. While reactions to failures in the data plane can be significantly faster compared to control plane mechanisms, implementing fast recovery in the data plane is challenging, and has recently received much attention in the literature. This survey presents a systematic,...
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Ocena skuteczności zarządzania polską marką
PublicationPrzedstawiono wybrane zagadnienia dotyczące zarządzania polską marką. są to przede wszystkim elementy wartości marki oraz jej tożsamości. problemy omówiono na przykładzie firmy wedel, która skutecznie zarządza swoją marką od ponad 150 lat.
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Pomiar kapitału marek własnych detalistów
PublicationCelem artykułu jest przybliżenie istoty pojęcia kapitału marek własnych, zaprezentowanie potencjalnych implikacji praktycznych i przedstawienie kierunków dalszych badań w tym zakresie.
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Zarządzanie marką w dobie nadpodaży
PublicationArtykuł poświęcony jest wskazaniu wyzwań stojących przed menedżerami marki wobec nadpodaży marek, produktów i informacji, będącymi pośrednią przyczyną marginalizacji marketingu jako funkcji wielu przedsiębiorstwach o organizacji „silosowej”, gdzie marketing często ograniczany jest do funkcji promocji. Wspomniane okoliczności, zdaniem autorki, mogą prowadzić zarówno do dalszej marginalizacji marketingu w wyniku spadku znaczenia...
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Circulating Tumor Cells as a Marker of Disseminated Disease in Patients with Newly Diagnosed High-Risk Prostate Cancer
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Properties of Ginkgo biloba L.: Antioxidant Characterization, Antimicrobial Activities, and Genomic MicroRNA Based Marker Fingerprints
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Liver fatty acid-binding protein might be a predictive marker of clinical response to systemic treatment in psoriasis
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Czy istnieje idealny marker zanieczyszczeń środowiska wodnego? Cz. I. Klasyczne parametry jakości wody
PublicationWoda jest substancją niezbędną do życia dla organizmów żywych. Ze względu na ważne role jakie odgrywa w przyrodzie i życiu człowieka, troska o jej jakość powinna być kluczowym aspektem działalności społeczeństwa. Pomimo wzrastającej świadomości prośrodowiskowej, do wody nadal wprowadzane są różnorodne zanieczyszczenia. W celu ich identyfikacji oraz określania źródła emisji wykorzystywane są tzw. markery zanieczyszczenia środowiska...
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Novel staphylococci nucH taxonomical marker used in identification of human-associated Staphylococcus succinus subsp. casei
PublicationThe aim of our study was to assess the sequencing of unique nucH gene fragment based on performed bioinformatics analysis as a novel diagnostic method for the identification of difficult to identify staphylococcal human pathogenic strains. Initially, PCR-RFLP-rrn analysis specific to the spacers between 16SrDNA and 23SrDNA followed by HhaI restriction analysis was performed. Further, sequencing of nucH and 16S rDNA genes fragments...
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Exchange-Traded Funds on European Markets: Has Critical Mass been Reached? Implications for Financial Systems.
PublicationExchange-traded funds (ETFs) are one of the most rapidly expanding categories of financial products in Europe. One of the key yet still unanswered questions is whether European ETF markets have reached the size at which they could affect the financial systems. In our study, we examine 13 European countries during the period 2004–2017 in order to trace whether the share of ETFs in the total assets of investment funds has reached...
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Investing in wine, precious metals and G-7 stock markets – A co-occurrence analysis for price bubbles
PublicationThis paper used the GSADF test to determine the periods defined in this paper as price bubbles in the three markets studied, i.e. the investment wine market, precious metal market and national stock market indices of G-7 countries. The results obtained enabled the calculation of the values of the phi correlation coefficients, which served the research objective of assessing the co-occurrence of price bubbles in the markets analysed....
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Carbon dioxide emissions and fuel consumption from passenger cars tested over the NEDC and WLTC – an overview and experimental results from market-representative vehicles
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KONFIGURACJA FIREWALLI CISCO ASA W PROGRAMIE PACKET TRACER
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Phoenixin as a New Target in the Development of Strategies for Endometriosis Diagnosis and Treatment
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CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma
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Data on the identification of microsatellite markers in Eisenia fetida and Eisenia andrei
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A semi-Markov model of fuel combustion process in a Diesel engine
PublicationW artykule przedstawiono czterostanowy model procesu spalania w przestrzeniach roboczych (cylindrach) silników o zapłonie samoczynnym w formie procesu semimarkowskiego, dyskretnego w stanach i ciągłego w czasie. Wartościami tego procesu są stany odpowiadające powszechnie akceptowanym rodzajom spalania w tego rodzaju silnikach a mianowicie takie stany procesu jak: spalanie pełne (całkowite i zupełne), spalanie niezupełne, spalanie...
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Sensorless control of high speed permanent-magnet synchronous motor
PublicationW artykule przedstawiono metodę bezczujnikowego sterowania szybkoobrotowym silnikiem z magnesami trwałymi. Pokazano działanie układu sterowania opartego na filtrze kalmana (EKF) jako obserwatora prędkości obrotowej.
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Hybrid-Excited Permanent Magnet-Assisted Synchronous Reluctance Machine
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Survival time prognosis under a Markov model of cancer development
PublicationIn this study we look at a breast cancer data set of women from Pomerania region collected in year 1987-1992 in the Medical University of Gdańsk. We analyze the clinical risk factors in conjunction with Markov model of cancer development. We evaluate Artificial Neural Network (ANN) survival time prediction via a simulation study.
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Sensorless Startup of Super High Speed Permanent Magnet Motor
PublicationCelem artykułu jest przedstawienie metody bezczujnikowego rozruchu wysokoobrotowego silnika z magnesami trwałymi. Zastosowano dwa typy metod sterowania. W pierwszej fazie rozruchu zastosowano metodę sterowania prądem, następnie przełączono do trybu sterowania wektorowego. Przy sterowaniu wektorowym zostały użyte: rozszerzony filtr Kalmana (EKF) oraz alternatywny Bezśladowy Filtr Kalmana (UKF) jako obserwatory prędkości obrotowej....
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Usage of Memi-Markov Process in Operation Evaluation of Diesel Engine
PublicationIn paper, the proposition of quantitative evaluation of operation using semi-Markov processes theories has been presented. Basic assumptions, essential for creating mathematical model on example of diesel engine were shown. Special attention was given to practical aspects of using established mathematical model. Example of characteristic of analysed process - temporary distribution of probability was assigned.
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Oxidative Stress as a Possible Target in the Treatment of Toxoplasmosis: Perspectives and Ambiguities
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On Some Aspects of Fish Target Strength Estimation in Shallow Waters
PublicationThe theory of acoustic surveys for determining fish abundance are well established in fishery acoustics. The origins of the estimation are related to overcoming the problem of unknown position of target in the beam using statistical inversion. Although recently researchers use more sophisticated echosounders that provides more informative data allowing for direct solution it is known that the results are biased due to not ideally...
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Analysis of MArkers of Exposure to Constituents of Environmental Tobacco Smoke (ETS)
PublicationTobacco smoke is a complex mixture of more than 4000 chemical compounds, many of which are harmful to human health. These compounds belong to various chemical classes, including amides, imides, lactams, carboxylic acids, aldehydes, ketones, alcohols, phenols, amines, hydrocarbons, ethers, and inorganic compounds. There are three types of tobacco smoke streams: the mainstream, the sidestream, and environmental tobacco smoke (ETS)....
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Experimental investigations and simulations of the microturbine unit with permanent magnet generator
PublicationIn dispersed power generation, low power devices are used for local combined generating of heat end electric power. There are developing concepts of micropower plants with electric generators driven by steam or gas microturbines. The paper presents the results of an experimental investigations of the microturbine set consists of the turbine with partial admission, permanent magnet generator and three phase AC-to-DC rectifier. The...
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Proposal of improvement to fairness mechanism of Resilient Packet Ring networks
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Lattice-commensurate skyrmion texture in a centrosymmetric breathing kagome magnet
PublicationSkyrmion lattices (SkL) in centrosymmetric materials typically have a magnetic period on the nanometer-scale, so that the coupling between magnetic superstructures and the underlying crystal lattice cannot be neglected. We reveal the commensurate locking of a SkL to the atomic lattice in Gd3Ru4Al12 via high-resolution resonant elastic x-ray scattering (REXS). Weak easy-plane magnetic anisotropy, demonstrated here by a combination...
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Chronic Rhinosinusitis—Microbiological Etiology, Potential Genetic Markers, and Diagnosis
PublicationChronic rhinosinusitis (CRS) is a significant public health problem. Bacterial colonization and impaired mucociliary clearance play a significant role in the inflammatory process. Several inflammatory pathways and host defense elements are altered in CRS, which may contribute to observed differences in the microbiome. To date, researching CRS has been difficult due to limited access to the studied tissue and a lack of available...
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Fish target strength estimation using multiple echo statistics
PublicationW pracy przedstawiono sposób określania statystycznych właściwości charakterystyki wiązki systemu hydroakustycznego z uwzględnieniem możliwości pojawienia się echo wielokrotnych od jednej ryby. Przedstawiono modele obejmujące dwa teoretyczne przypadki związane z wzajemnym ruchem statku i pojedynczej ryby i pokazano, że posiadają one zbliżone właściwości statystyczne. Rozważania teoretyczne potwierdzone są analizą przykładowych...
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Receiver of Doppler multistatic system for moving target detection and tracking
PublicationThe article presents a method for solving major structural problems that occur in the receiver used in the multistatic Doppler system, aimed at determination of the trajectory and velocity of a moving target. In the system two transmitters emit acoustic continuous sinusoidal waves at different frequencies. The signals, scattered from a moving target are received by four hydrophones. Beside of the echoes, much larger signals coming...
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Wartość marki jako wskaźnik. Metody pomiaru
PublicationCelem artykułu jest przedstawienie znaczenia wskaźnika „wartość marki”1 dla celów optymalizacji strategii marketingowych w oparciu o przegląd metod pomiaru zarówno pod kątem zarządczym, jak i raportowania. Wartość marki stanowi najbardziej obiektywny wskaźnik oceny przyjętej strategii marketingowej oraz sprawności skonfigurowanej sieci wartości marki z powodu możliwości jednoznacznej oceny, czy przyjęty „marketing mix” zapewnił...
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Kapitał marki miasta Gdańska - ujęcie marketingowe
PublicationKapitał marki miasta obejmuje zestaw jego unikalnych cech, które umożliwiają rywalizowanie o potencjalnych klientów: mieszkańców, turystów, studentów czy też inwestorów. Niniejszy rozdział dotyczy problematyki czynników kształtujących markę miasta Gdańsk określonych na podstawie wyników badania jakościowego. Zostało ono przeprowadzone w formie wywiadu z ekspertami zajmującymi się zawodowo kreowaniem marki miast. Wyboru respondentów...
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Symulacja skrócenia procesu kompletacji z wykorzystaniem karty przebiegu czynności na przykładzie wybranego marketu DIY
PublicationW artykule przeanalizowano zagadnienia dotyczące gospodarki magazynowej, wykorzystania infrastruktur magazynowej i manipulacyjnej oraz zagospodarowania przestrzeni magazynowej w zakresie realizowanych procesów w magazynie wybranego marketu budowlanego DIY (ang. Do-It-Yourself). Z wykorzystaniem takich narzędzi, jak mapa procesu oraz karta przebiegu czynności przeprowadzono analizę procesu kompletacji towarów dla wybranego zamówienia...
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Stock Markets’ Reactions to the Announcement of the Hosts. An Event Study in the Analysis of Large Sporting Events in the Years 1976–2032
PublicationThis study attempts to estimate the impact of the announcements of hosts of large sporting events on domestic stock markets. The research problem is to establish a connection between the uniqueness of a sporting event and investors’ beliefs through stock price behavior. Using appropriate estimation windows, 13 different sporting events classified as large, including mega and major events, were tested. The obtained results show...
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Origin of the ornamented bâton percé from the Gołębiewo site 47 as a trigger of discussion on long-distance exchange among Early Mesolithic communities of Central Poland and Northern Europe
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PUBLIC SPACES FOR LOCAL LIFE / Shared values in diversified urban communities as a foundation for participatory provision of local public spaces, 23-27 May 2017, Ljubljana Slovenia
PublicationThe Urban Planning Institute of the Republic of Slovenia (UIRS) and partners hosted a 5-day international event addressing participatory planning of local urban public space in socially, economically and ethnically diverse communities. The event was structured in three interrelated activities: a seminar, a workshop and a field-trip. Special emphasis was given to the means of revealing shared values that local inhabitants and other...
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Market Price Prediction of Property Rights from Gas Fired Plants or Plants with Total Installed CHP Source Capacity Below 1 MW until 2025
PublicationThe resolution on the Polish Energy Policy until 2030 (PEP-30) was adopted by the Council of Ministers on 10 November 2009. The document specifies the combined electricity and heat generation as a direction of pursuing the goals of energy efficiency, fuel and energy supply security, competitive fuel and energy markets development, and reduction of the energy sector’s environmental impact. PEP-30 assumes that electricity generation...
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Hospital as a landscape mark
PublicationHalf of the nineteenth century brought significant changes in the organization and operation of hospitals. The on-coming takeover by the state and its agencies tasks related to medical care resulted in a significant jump in quantitative and almost massive construction of new hospitals. Several hospitals and nursing homes functioned on a relatively small area of a city or town, with different specializations and profiles of care....
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Make lighting healthier
PublicationLife on Earth evolved in day-and-night cycles. Plants and animals, including insects such as the fruit fly, have a biological clock that controls their circadian rhythms — as the 2017 winners of the Nobel Prize in Physiology or Medicine showed. Now, humans’ increasing reliance on artificial lighting is changing those rhythms.
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The rs1447295 and DG8S737 markers on chromosome 8q24 and cancer risk in the Polish population
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Selected mitochondrial genes as species markers of the Arctic Contracaecum osculatum complex
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ZARZĄDZANIE SIECIAMI KOMPUTEROWYMI W PROGRAMIE PACKET TRACER - WIADOMOŚCI PODSTAWOWE
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ZARZĄDZANIE SIECIAMI KOMPUTEROWYMI W PROGRAMIE PACKET TRACER - WIADOMOŚCI ZAAWANSOWANE
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Postmortem Determination of Short-Term Markers of Hyperglycemia for the Purposes of Medicolegal Opinions
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Horizontally-split-drain MAGFET - a highly sensitive magnetic field sensor
PublicationWe propose a novel magnetic field sensitive semiconductor device, viz., Horizontally-Split-Drain Magnetic-Field Sensitive Field-Effect Transistor (HSDMAGFET) which can be used to measure or detect steady or variable magnetic fields. Operating principle of the transistor is based on one of the galvanomagnetic phenomena and a Gradual Channel Detachment Effect (GCDE) and is very similar to that of Popovic and Baltes's SDMAGFET. The...
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Hard tissue samples as markers of occupational exposure in phosphatic fertilizer plant
PublicationW pracy opisano zastosowanie próbek włosów i paznokci do oceny narażenia pracowników zakładów nawozów fosforowych na zanieczyszczenie metalami ciężkimi. Jako metodę oznaczania 25 pierwiastków we włosach i paznokciach zastosowano aktywacje neutronową. Do opracowania wyników i ich oceny zastosowano szereg metod chemometrycznych.
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Research on a permanent magnet assisted synchronous reluctance machine with hybrid excitation
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