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Search results for: EAR PINNA
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Epigenetic inhibitor zebularine activates ear pinna wound closure in the mouse
PublicationBackground:Most studies on regenerative medicine focus on cell-based therapies and transplantations.Small-molecule therapeutics, though proved effective in different medical conditions, have not been extensivelyinvestigated in regenerative research. It is known that healing potential decreases with development and devel-opmental changes are driven by epigenetic mechanisms, which suggests epigenetic repression of regenerativecapacity.Methods:We...
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Regenerative Drug Discovery Using Ear Pinna Punch Wound Model in Mice
PublicationThe ear pinna is a complex tissue consisting of the dermis, cartilage, muscles, vessels, and nerves. Ear pinna healing is a model of regeneration in mammals. In some mammals, including rabbits, punch wounds in the ear pinna close spontaneously; in common-use laboratory mice, they remain for life. Agents inducing ear pinna healing are potential regenerative drugs. We tested the effects of selected bioactive agents on 2 mm ear pinna...
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Correlations between the wear of car brake friction materials and airborne wear particle emissions
PublicationAirborne wear particles emitted from transport vehicle brakes are one of the main sources of toxic metals in inhalable particulate matter. Prediction of wear particle emissions may become more accurate if the relationship between the wear and particle emission characteristics is known. An experimental study was performed to investigate proportional correlations between the mass wear, 0.01–0.42 μm particle emission measured by a NanoScan...
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Types of wear and tear of biomaterials used in orthopaedic surgery
PublicationPurpose of this paper is presentation of observations on different kinds of wear and tear of biomaterials used in contemporary orthopaedic surgery. Types of prosthesis damage, encountered in medical practice, and their causes have been described. Results of many clinical studies were analysed to review prosthesis damage from the stage of implanting (such as intrusion of a foreign object between its components) to their natural...
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Effective density of airborne wear particles from car brake materials
PublicationPeople living in urban environments are subject to high health risks due to various anthropogenic sources of airborne particulate matter, including wear of transport vehicle brakes. Studies of airborne particles often require an estimate of the effective particle density, a property that allows correct matching of mass and size characteristics measured by different aerosol instruments. In this study we investigated the effective...
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Activation of endogenous regenerative potential in mammals using epigenetic inhibitor zebularine
PublicationIn this work, a nucleoside inhibitor of DNA methyltransferases, zebularine, was investigated as a wound healing and regeneration promoting agent. It was found that a high dose of intraperitoneally delivered zebularine improved punch wound closure in the ear pinna in mice. Both cytidine, a zebularine analogue, and uridine, a zebularine metabolite, did not promote ear pinna hole closure. The effect of zebularine on ear pinna healing...
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A Study on Emission of Airborne Wear Particles from Car Brake Friction Pairs
PublicationThe emission of airborne wear particles from friction material / cast iron pairs used in car brakes was investigated, paying special attention to the influence of temperature. Five low-metallic materials and one non-asbestos organic material were tested using a pin-on-disc machine. The machine was placed in a sealed chamber to allow airborne particle collection. The concentration and size distribution of 0.0056 to 10 μm particles...
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Quantification of ultrafine airborne particulate matter generated by the wear of car brake materials
PublicationThe wear of car brakes is one of the main sources of airborne particulate matter in urban environments. Ultrafine wear particles are of special environmental interest since they can easily penetrate the human body through inhalation and cause various diseases. In the present study, the contribution of ultrafine particles to airborne particulate matter emitted from car brake materials was investigated under different friction conditions....
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Odnawialne źródła enegi cy energetyka jądrowa- pinia społeczna
PublicationW artykule zaprezentowano obecny stan i możliwości energii produkowanej z odnawianlych źródel energii (OŹE). W pracy przedstawiono uzasadnienie ekonomiczne oraz uwarunkowania środowiskowe dla wykorzystania konkretnych źródeł energii odnawialnej. Opinia wykreowana na podstawie przesłanek ekonomicznych i technicznych przeciwstawiona zostala opinii społecznej uzyskanej na podstawie ankiety. W artykule poruzsony został także temat...
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Intensywny spływ. Inna filozofia projektowania kanalizacji deszczowej.
PublicationZmiany zasad określania deszczy obliczeniowych w kanalizacji. Dążenie do efekty katastrofy kontrolowanej.
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Transforming a Traditional, Family-Run Car Dealership into a Digital-Era Modern Service Provider
PublicationThe automotive industry today faces multiple challenges. The automotive market is characterised by frequent changes and technological developments in comfort and safety of travel by all types of vehicles. The division between traditional and modern services is related to their susceptibility to technological progress. We should differentiate between two types of technology: technology used directly in vehicles and technology utilized...
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Quasi-analytical Near-to-Far Field Transformation Based on Field Matching Method for Scattering Problems
PublicationA new quasi-analytical near-to-far field transformation based on field matching method (field expansion in a base of Hankel functions) is presented. This approach uses finite element method to obtain near field, then the field is expressed in a base of Hankel functions. The evaluated coefficients allow to calculate the field outside the numerical domain, also in a far distance. The main advantage of the proposed technique is avoiding of...
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Static and dynamic approach of social roles identification using PISNA and subgraphs matching
PublicationIdentyfikacja ról w sieci społecznej jest jednym z podstawowych zagadnień analiza takich sieci. W artykule przedstawiamy nowe podejście do tego zagadnienia. Pokazujemy w jaki sposób można dokonać identyfikacji ról poprzez tworzenie specjalnych struktur grafowych tzw. grafów wzorcowych. Przy definiowaniu tychże grafów wspieramy się metodą PISNA. Proponujemy statyczne i dynamiczne podejście do identyfikacji ról. Pokazujemy, w jaki...
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The ear as a location for wearable vital signs monitoring
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Thermal Barrier Stability and Wear Behavior of CVD Deposited Aluminide Coatings for MAR 247 Nickel Superalloy
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Abrasive Wear, Scuffing and Rolling Contact Fatigue of DLC-Coated 18CrNiMo7-6 Steel Lubricated by a Pure and Contaminated Gear Oil
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A Comparative Study on Methods of Distinction Between Near- and Far-Side Defects as Techniques Used Alongside with the Magnetic Flux Leakage Testing
PublicationResults of the finite element analysis show that a far-side defect in a steel plate, with the depth greater by 10% of the plate thickness than a near-side defect, can produce a very similar magnetic flux leakage (MFL) signal. Due to the fact that a measurement of MFL itself can lead to misclassification of a far-side defect as a near-side one, and thus to underestimation of its depth, a comparative study of three complementary...
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Comparative wear test of journal sliding bearings with sintered bronze and Babbitt alloy bushes lubricated by environmentally acceptable/adapted lubricants (EAL)
PublicationA growing awareness of the negative effects of mineral oils on the natural environment has resulted in the introduction of new regulations related to environmental protection. One of these regulations requires the use of environmentally acceptable/adapted lubricants (EAL) to lubricate marine main shaft bearings, in place of the mineral lubricating oils that have been used for decades. Classification Societies, which supervise...
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Triaquabis(tri-tert-butoxysilanethiolato)barium
PublicationReakcja metalicznego baru z tri-tert-butoksysilanotiolem w obecności śladów wody daje [Ba(C12H27O3SSi)2(H2O)3]. Atom baru koordynowany jest przez dwie reszty silanotiolanowe w sposób chelatujący (jako O,S-ligandy) oraz przez atomy tlenu z trzech cząsteczek wody, tworząc międzycząsteczkową sieć wiązań wodorowych typu O--H...O i O--H...S.
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Chapter 12 ESR and ESR Imaging Methods for the Study of Oxidative Polymer Degradation
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Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublicationDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
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On the Consumption of Multimedia Content Using Mobile Devices: a Year to Year User Case Study
PublicationIn the early days, consumption of multimedia content related with audio signals was only possible in a stationary manner. The music player was located at home, with a necessary physical drive. An alternative way for an individual was to attend a live performance at a concert hall or host a private concert at home. To sum up, audio-visual effects were only reserved for a narrow group of recipients. Today, thanks to portable players,...
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The Microwave Sources for EPR Spectroscopy
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The gyrotron source for the EPR spectroscopy
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The trends in modern car wash
PublicationPrzedstawiono przegląd różnych technik mycia samochodów ze szczególnym uwzględnieniem zużycia wody. Podano także nowoczesne wykorzystanie odwróconej osmozy z polimerowymi membranami do oczyszczania wody w zamkniętym obiegu myjni samochodowych.
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Neurocontrolled Car Speed System
PublicationThe features of the synthesis of neural controllers for the car speed control system are considered in this article. The task of synthesis is to determine the weight coefficients of neural networks that provide the implementation of proportional and proportional-integralderivative control laws. The synthesis of controllers is based on an approach that uses a reversed model of the standard. A model of the car speed control system with...
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Investigation of the 16-year and 18-year ZTD Time Series Derived from GPS Data Processing
PublicationThe GPS system can play an important role in activities related to the monitoring of climate. Long time series, coherent strategy, and very high quality of tropospheric parameter Zenith Tropospheric Delay (ZTD) estimated on the basis of GPS data analysis allows to investigate its usefulness for climate research as a direct GPS product. This paper presents results of analysis of 16-year time series derived from EUREF Permanent Network...
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Wear of Farm Buildings in Selected Farms
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Saturation ESR spectroscopy of PA12 polyamide
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Nowa era szkła w budownictwie
PublicationPrzywołano wielką aktualność szkła jako materiału wypełniającego i konstrukcyjnego w budownictwie. Nowa ere szkła stawia projektantom zupełnie nowe zadania. Twory natury i efekty pracy rąk ludzkich powinny dziś mieć równą możliwość wzajemnego przenikania się. Artykuł zawiera stosowne informacje.
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Dear Readers of "Palliative Medicine in Practice”
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Theory and application of Near-infrared spectroscopy
PublicationIn recent years one can observe a significant increase in the requirements on quality control in all industrial sectors. The growing number of involved analyses makes the traditional, time consuming, requiring use of large quantities of reagents, thus expansive methods inconvenient especially for industrial applications. Fortunately, there is a very fast, cheap and not invasive analytical method that is increasingly used in qualitative...
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The integrals of velocity near the tissue in bioreactor.
PublicationWykazano, że siły tarcia występujące w trakcie hodowli decydują o jakości wzostu tkanki i jej planowanych, zamierzanych właściwościach. Siły tarcia wyznaczamy z pola prędkości cieczy biologicznej przepływającej wokół powierzchni tkanki. Dlatego w pracy tej wyznacza się pole prędkości przepływu cieczy biologicznej w cienkiej warstewce przyściennej. Wyznaczone analitycznie pole prędkości charakteryzuje się newtonowskimi właściwościami...
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Simulation and identification of damage in bar structures.
PublicationPraca zawiera opis i testy 3 procedur badawczych dotyczących lokalizacjizniszczeń w konstrukcjach. Procedury bazują na danych modalnych jakie obiektgeneruje podczas swoich drgań tzn. częstościach własnych i postaciach drgań Badane są zmiany podatności układu, zmiany krzywizn postaci drgań i wrażli-wość częstości na założone zniszczenia. Odpowiednie procedury wiążące się ztymi trzema metodami są przestestowane na przykładzie wspornika...
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GRSP`s fourth year in Poland.
PublicationThis paper gives an extensive run through of two projects of the GRSP initiative carried out by Shell to mark a decade of the companyłs contribution to the GAMBIT Programme. It brings some information about the activities of the Polish GRSP Committee in 2002, and about last year International Seminar GAMBIT 2002.
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Water Behavior Near the Lipid Bilayer
PublicationIn this chapter, we focus on the dynamics of water molecules situated in the vicinity of a phospholipid bilayer. Using a molecular dynamics simulation method, we studied interactions between water and the bilayer and tracked trajectories of the water molecules. Based on the hypothesis that molecules trapped inside the bilayer make different motions than the ones which are either attached to the surface or move freely in the water...
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The Interconnectedness between Institutional Quality, Civil War and Institutional Reform: A Case Study of Nepalese Maoist Civil War
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Comparison of near infrared spectroscopy (NIRS) and near-infrared transillumination-backscattering sounding (NIR-T/BSS) methods
PublicationThe aim of the study was to compare simultaneously recorded a NIR-T/BSS and NIRS signals from healthy volunteers. NIR-T/BSS is a device which give an ability to non-invasively detect and monitor changes in the subarachnoid space width (SAS). Experiments were performed on a group of 30 healthy volunteers (28 males and 2 females, age 30.8 ± 13.4 years, BMI = 24.5 ± 2.3 kg/m2). We analysed recorded signals using analysis methods based...
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Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains
PublicationAims We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. Materials and Methods Global DNA methylation profiling was performed in ear pinnae, bone marrow, spleen, liver, heart from uninjured adult females of the MRL/MpJ and C57BL/6J and BALB/c. Results and conclusion A number of differentially methylated regions distinguishing between...
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Thermal Aging of Heterophasic Propylene−Ethylene Copolymers: Spatial and Temporal Aspects of Degradation Based on ESR, ESR Imaging, and FTIR
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Grease effect on fretting wear of mild steel
PublicationNa stanowisku laboratoryjnym przeprowadzono badania zużycia frettingowego miękkiej stali smarowanej mineralnymi i syntetycznymi smarami zawierającymi także różne dodatki: grafit dwusiarczek molibdenu ZDDP i ditiocarbamat molibdenu, w różnych stężeniach.Badania wykazały istotny wpływ konsystencji smaru i jego właściwości smarnych na zużycie frettingowe miękkiej stali oraz zróżnicowany wpływ testowanych dodatków. Obecność smaru...
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Application of the near-infrared spectroscopy in the pharmaceutical technology
PublicationNear-infrared (NIR) spectroscopy is currently the fastest-growing and the most versatile analytical method not only in the pharmaceutical sciences but also in the industry. This review focuses on recent NIR applications in the pharmaceutical technology. This article covers monitoring, by NIR, of many manufacturing processes, such as granulation, mixing or drying, in order to determine the end-point of these processes. In this...
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New generation cooling systems for car engines
PublicationNormy czystości spalin silników samochodowych wymusiły rozwój elektronicznego sterowania pracą silników samochodowych. Do niedawna układy chłodzenia były bardzo tradycyjnymi - niesterowanymi programowo. W artykule przedstawiono możliwości wprowadzenia zaawansowanego sterowania mikroprocesorowego do układów chłodzenia silników spalinowych. Rozważania zilustrowano badaniami z literatury i własnymi pomiarami autora.
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The influence of contact geometry on friction and wear characteristics
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The Crisis of Marketing Communication in the Era of Social Media
PublicationThe articles examines the widely discussed in literature the problem of marketing communication crisis resulting from the changes of the environment. These changes generate both new problems and also new solutions, e.g. social media. The practicioners are pursuing both effective and efficient solutions, in relation to the difficulties encountered while achieving market objectives via traditional methods and channels. In accordance...
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Microbiological Hazard Analysis of Car Wash Wastewater
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The wave character of commutator wear in electrical machines
PublicationW pracy przedstawiono wyniki badań doświadczalnych zużycia elementów ze styku ślizgowego silnika komutatorowego prądu przemiennego małej mocy. Zakres badań obejmował okresowe pomiary profilu powierzchni ślizgowej komutatora w przekroju poprzecznym oraz profilu powierzchni wycinków komutatora w przekroju podłużnym względem osi wirowania. Ponadto zmierzono okresowe wielkości zużycia powierzchni ślizgowej komutatora oraz szczotek...
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Worm Gear Drives with Improved Kinematic Accuracy
PublicationThis paper presents the fundamentals of the design and applications of new worm gear drive solutions, which enable the minimisation of backlash and are characterised by higher kinematic accuracy. Different types of worm surfaces are briefly outlined. Technological problems concerning the principles of achieving a high degree of precision in machining are also described. Special attention is paid to the shaping of conical helical...
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ASSESSMENT OF WEAR OF THE BANDSAW TEETH IN INDUSTRIAL CONDITIONS
PublicationA methodology for measuring bandsaw tooth wear is presented in this paper. This type of measurement is proposed as an alternative way of determining tooth wear in industrial conditions. The method is based on determining the KE value, i.e., the distance of the radius of the rounded cutting edge of the tooth and the intersection of the surface of the back and the surface of the face of the cutting wedge of the bandsaw tooth....
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Fretting wear of materials - methodological aspects of research
PublicationW artykule przedstawiono metodyczne aspekty frettingowego zużywania materiałów. Rezultaty badań przeprowadzonych na stanowisku typu ''pin on disc'' wykonanym w Katedrze Inżynierii Materiałowej i Biomedycznej Politechniki Białostockiej potwierdziły decydujący wpływ amplitudy oscylacji i wartości obciążenia na przebieg i charakter procesu zużywania. Wzrost wartości amplitudy powodował zmiany w warunkach tarcia. Wzrost wartości obciążenia...