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Search results for: CELE MOLEKULARNE
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The Reduced Folate Carrier (SLC19A1) c.80G>A Polymorphism is Associated with Red Cell Folate Concentrations Among Women
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Bacteria Residing at Root Canals Can Induce Cell Proliferation and Alter the Mechanical Properties of Gingival and Cancer Cells
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New and Old Genes Associated with Primary and Established Responses to Cisplatin and Topotecan Treatment in Ovarian Cancer Cell Lines
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Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines
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Microarray-based detection and expression analysis of new genes associated with drug resistance in ovarian cancer cell lines
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“Cell Migration” Is the Ontology Group Differentially Expressed in Porcine Oocytes Before and After In Vitro Maturation: A Microarray Approach
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The Effects of Cellular Membrane Damage on the Long-Term Storage and Adhesion of Probiotic Bacteria in Caco-2 Cell Line
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Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma
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AP-MOVPE Technology and Characterization of InGaAsN p-i-n Subcell for InGaAsN/GaAs Tandem Solar Cell
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Determination of pyridine and adenine nucleotide metabolites in Bacillus subtilis cell extract by sweeping borate complexation capillary electrophoresis
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Bacterial Nanocellulose Fortified with Antimicrobial and Anti-Inflammatory Natural Products from Chelidonium majus Plant Cell Cultures
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Nanoconjugates of graphene oxide derivatives and meso-tetraphenylporphyrin: a new avenue for anticancer photodynamic therapies – Cell-on-a-Chip analysis
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Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells
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Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche
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Clinical significance of CD34, podoplanin and Ki-67 expression in patients with locally advanced squamous cell cervical carcinoma
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Comparison of siRNA-mediated silencing of glycosaminoglycan synthesis genes and enzyme replacement therapy for mucopolysaccharidosis in cell culture studies.
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DNA structure and integrity checkpoints in the cell cycle and their role in drug targeting and resistance of tumor cells to anticancer treatment
PublicationW artykule dokonaliśmy przeglądu literatury dotyczącej różnych typów uszkodzeń DNA indukowanych przez różne czynniki terapeutyczne w komórkach nowotworowych. Omówiliśmy także w jaki sposób aktywują różne typy punktów kontrolnych w cyklu komórkowym i w jaki sposób punkty te są regulowane przez inne szlaki sygnalizacji wewnątrzkomórkowej takie jak szlaki naprawy uszkodzeń DNA, stresu komórkowego i śmierci-przeżycia. W szczególności...
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Ocena możliwości zmiany struktury układu regulacji prędkości kątowej turbozespołu w celu eliminacji synchronizatora automatycznego
PublicationW artykule podano propozycję zmiany struktury układu regulacji turbozespołu, w celu eliminacji synchronizatora automatycznego w procesie łączenia. Wykonano szereg analiz w zakresie zmian kąta niezgodności fazowej i omówiono najistotniejsze wyniki badań (materiał był również prezentowany na konferencji PPEEm 2011).
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Chromatographic analyses of Lavandula angustifolia and Rosmarinus officinalis extracts and their biological effects in mammalian cells and cell-free systems
PublicationKnowledge of biological properties of natural compounds allows to understand their therapeutic value, efficacy and security. We investigated: composition of Lavandula angustifolia (LA) and Rosmarinus officinalis (RO) extracts, their antioxidant capacity, cytotoxicity and genotoxicity, their DNA-protective potential against DNA damage induced in hamster V79 cells by several genotoxins or in plasmid DNA by Fe2+ ions and activity...
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Rapid design of miniaturised branch-line couplers through concurrent cell optimisation and surrogate-assisted fine-tuning
PublicationIn this study, the authors introduce a methodology for low-cost simulation-driven design optimisation of highly miniaturised branch-line couplers (BLCs). The first stage of their design approach exploits fast concurrent optimisation of geometrically dependent, but electromagnetically isolated cells that constitute a BLC. The cross-coupling effects between the cells are taken into account in the second stage, where a surrogate-assisted...
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Numerical modeling of exciton impact in two crystalographic phases of the organo-lead halide perovskite (CH3NH3PbI3) solar cell
PublicationTo improve the power conversion efficiency of solar cells based on organo–lead halide perovskites, a detailed understanding of the device physics is fundamental. Here, a computational analysis of excitons impact is reported for these types of photocell. Numerical calculations based on the model, which take into account electronic charge carriers (electrons and holes), excitons and ions, have been carried out. The role of excitons...
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Label-free testing strategy to evaluate packed red blood cell quality before transfusion to leukemia patients
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Synthesis of isomeric, oxathiolone fuded chalcones and comparison of their activity toward various microorganisms and human cancer cell lines
PublicationIzomeryczne oksationolowe sprzężone chalkony otrzymano w wyniku kondensacji odpowiedniego acetylobenzo[1,3]oksatiolo-2-onu z aldehydem benzoesowym w środowisku kwaśnym. Określono aktywność cytotoksyczną otrzymanych związków wobec komórek linii HeLa, przeciwbakteryjną wobec Micrococcus luteus, Staphylococcus aureus, Salmonella typhimurium, Escherichia coli i Proteus vulgaris, przeciwgrzybową wobec Candida albicans i tuberkulostatyczną...
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Improved performance of LaNi0.6Fe0.4O3 solid oxide fuel cell cathode by application of a thin interface cathode functional layer
PublicationIn this work, novel functional layers were prepared by a low temperature spray pyrolysis method on the oxygen side of the solid oxide cells. Thin layers of Ce0.8Gd0.2O2 and LaNi0.6Fe0.4O3 are prepared between the electrolyte and the porous oxygen electrode. Additionally the influence of the sprayed ceria barrier layer on the zirconia based electrolyte with the new layers is evaluated. Impedance spectroscopy results show improvement...
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Ocena możliwości zmiany struktury układu sterowania prędkością kątową turbozespołu w celu eliminacji synchronizatora automatycznego
PublicationW artykule przedstawiono propozycję zmiany struktury układu regulacji turbozespołu parowego w celu eliminacji synchronizatora automatycznego, w procesie łączenia. Wykonano szereg analiz w zakresie zmian kąta niezgodności fazowej oraz omówiono najistotniejsze wyniki badań.
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Evaluation of inhibition of cancer cell proliferation in vitro with different berries and correlation with their antioxidant level by advanced analytical methods
PublicationW pracy opisano wyniki badań:- właściwości przeciwutleniających ekstraktów rozpuszczalnikowych (DMSO) uzyskanych z różnych gatunków owoców jagodowych- zdolność do infibizacji proliferacji komórek rakowych.W badaniach wykorzystano testy (DPPH) oraz zaawansowane techniki analityczne (spektroskopia FTIR oraz fluoroscencja 3D)Wyniki badań wskazują, że spożywanie owoców jagodowych może zredukować zagrożenie procesu proliferacji komórek...
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Dual-Activity Fluoroquinolone-Transportan 10 Conjugates offer alternative Leukemia therapy during Hematopoietic Cell Transplantation
PublicationHematopoietic cell transplantation (HCT) is often considered a last resort leukemia treatment, fraught with limited success due to microbial infections, a leading cause of mortality in leukemia patients. To address this critical issue, we explored a novel approach by synthesizing antileukemic agents containing antibacterial substances. This innovative strategy involves conjugating fluoroquinolone antibiotics, such as ciprofloxacin...
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The impedance of hydrogen oxidation reaction in a proton exchange membrane fuel cell in the presence of carbon monoxide in hydrogen stream
PublicationEvaluation of performance of a proton exchange membrane fuel cell, which is affected by carbon monoxide that pollutes the hydrogen stream, was presented. This influence was studied for carbon monoxide concentration of 125–325 ppb, which are close to values specified in ISO 14687:2019 standard. Performed studies provided crucial information for further development of fuel cell as an energy source for automotive application. Impedance...
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Recent advances on spinel-based protective coatings for solid oxide cell metallic interconnects produced by electrophoretic deposition
PublicationThe application of ceramic protective coatings to the metallic interconnects in solid oxide cells (SOCs) is a viable and effective method to limit interconnect degradation issues. This featured letter provides a critical overview of the main outcomes of current research on the use of the electrophoretic deposition (EPD) technique to produce protective coatings for SOC metallic interconnects, specifically focusing on different approaches...
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Highly crystalline colloidal nickel oxide hole transport layer for low-temperature processable perovskite solar cell
PublicationHighly crystalline NiOX usually requires high annealing temperature (>300 °C) which is incompatible with flexible substrate and might consume high amount of energy. Herein, we demonstrate a facile emulsion process to synthesize highly crystalline, low temperature deposition (<150 °C) and solution processable NiOx nanoparticles (NPs) as a hole transport layer for the perovskite solar cells (PVSCs). A novel surfactant of tetramethylammonium...
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Physical and sealing properties of BaO–Al2O3–SiO2–CaO–V2O5 glasses for solid oxide fuel cell applications
PublicationIn this study, the properties of BaO–Al2O3–SiO2 (SAB) glasses incorporated with CaO and V2O5 as the network modifier and additive, respectively, are evaluated. The electrical resistivities of the glasses decrease upon the addition of CaO but increase upon increasing their V2O5 content because the V5+ species lower the ionic mobility of the glasses. The addition of V2O5 improves the wettability of the glasses on the Crofer 22 APU...
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Stability Analysis of the Floating Offshore Wind Turbine Support Structure of Cell Spar Type During its Installation
PublicationThe article presents the results of selected works related to the wider subject of the research conducted at the Faculty of Ocean Engineering and Ship Technology of the Gdansk University of Technology, which concerns design and technology of construction, towing, and settlement on the seabed, or anchoring, of supporting structures for offshore wind farms. As a result of this research, several designs of this type of objects were...
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Synthesis of new antrapyridazone derivatives - a novel group of anticancer agents active on a multidrugresistant(MDR) tumor cell lines
PublicationNovel antrapyridazone derivatives were synthesized and biologically evaluated in order tobroaden the data on structure-activity relationship of this class of cytostatics. Recent literaturedata prove that acetamides react better with aryl chlorides. A new approach based onintroduction of other amides form into aromatic ring in Ullmann was tested. This new methodcould give better yields and make purification step more convenient.
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Analiza działań podjętych w celu zmniejszenia tempa ocieplania się klimatu i ich skutki ekonomiczne
PublicationNie ma całkowitej pewności, co do roli człowieka w ociepleniu się klimatu na Ziemi. Obecnie coraz więcej osobistości świata nauki przeczy tezom głoszonym przez IPCC, poszukują oni innych przyczyn podwyższania się temperatury na ziemskim globie. Nie mniej jednak społeczność międzynarodowa przeforsowała szereg dyrektyw i rozporządzeń, mających przeciwdziałać wzrostowi emisji dwutlenku węgla i innych gazów cieplarnianych do atmosfery....
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Application of wet powder spraying for anode supported solid oxide fuel cell with a perowskite SrTi0.98Nb0.02O3-d anode
PublicationAnode-supported solid oxide fuel cell with SrTi0.98Nb0.02O3–d anode, yttria-stabilized zirconia electrolyte and La(Ni0.6Fe0.4) O3d cathode has been successfully fabricated and evaluated. Process of anode support fabrication has been presented. Wet powder spraying and high temperature sintering method have been studied and applied to deposit the thin electrolyte layer.In order to improve catalytic properties of the anode, it has...
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New patterns in the position of CEE countries in global value chains: functional specialisation approach
PublicationResearch background: High servitisation of manufacturing makes it impossible to separate services from manufactured goods properly, which implies difficulties in the assessment of the position of the country on the smile curve, i.e. in the proper assignment of products or services to one of the industrial process steps: pre-production, pure fabrication or post-production services. Therefore, we propose to use the business functions...
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Agnieszka Potęga dr inż.
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Glucosamine-6-phosphate synthase - the multi-facets enzyme
PublicationAmidotransferaza L-glutamina: D-frukozo-6-fosforan, nazywana zwyczajowo syntazą glukozamino-6-fosforanu, jako jedyny enzym należący do grupy amidotransferaz, nie wykazuje aktywności amoniakozależnej. Enzym ten, katalizujący pierwszy wyjątkowy etap w szlaku metabolicznym prowadzącym do ostatecznego wytworzenia 5´difosfourydyno-N-acetylo-D-glukozaminy (UDG-GlcNAc) stanowi ważny punkt kontroli metabolicznej biosyntezy makromolekuł...
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Cell and Bioscience
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Cell Surface
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EUKARYOTIC CELL
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TISSUE & CELL
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Cell Reports
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Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.
ProjectsProject realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2015/17/B/NZ6/04248 agreement from 2016-02-15
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Organiczne baterie słoneczne ze zdyspergowanym złączem na bazie polimerów półprzewodnikowych o wąskiej przerwie energetycznej
PublicationPrzeprowadzono badania nad zwiększeniem wydajności prądowej organicznych baterii słonecznych ze złączem objętościowym, zbudowanych z syntetycznych polimerów półprzewodnikowych, posiadających rozległe wiązania π-sprzężone i charakteryzujących się długofalową granicą absorpcji optycznej. Przeanalizowano wpływ domieszek typu n i zmiany materiału katody na molekularny proces transferu nośników ładunku w złączu. Przeprowadzono pomiary...
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Nowoczesne metody diagnostyki zakażeń dermatofitowych
PublicationGrzyby należące do rodzajów Microsporum, Trichophyton i Epidermophyton są główną przyczyną powierzchownych zakażeń grzybiczych. Klasyczna identyfikacja gatunkowa czynnika etiologicznego tych grzybic oparta na obserwacjach mikro- i makroskopowych możliwa jest dopiero po uzyskaniu czystej hodowli dermatofitów. W związku z powolnym tempem wzrostu jest ona możliwa po dwóch, trzech tygodniach po pobrania próbki. Molekularne metody diagnostyczne...
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Monitoring T-Cell Responses in Translational Studies: Optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-Specific Responses
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Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D2 Against Human Malignant Melanoma Cell Lines
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Geldanamycin-Induced Osteosarcoma Cell Death Is Associated with Hyperacetylation and Loss of Mitochondrial Pool of Heat Shock Protein 60 (Hsp60)
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Expression of stem cell and mesenchymal markers in circulating tumor cells is associated with poor prognosis of early breast cancer patients
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