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Wyniki wyszukiwania dla: SAMPLE PREPARATION METHOD HUMAN BREAST MILK LIPID EXTRACTION METABOLITE EXTRACTION METABOLOMICS LIPIDOMICS HUMAN BREAST MILK CONTAMINANTS
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Effect of sample-preparation methods on the quantification of selected flavonoids in plant materials by high performance liquid chromatography
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Rapid and simple multi-analyte LC–MS/MS method for the determination of benzodiazepines and Z-hypnotic drugs in blood samples: Development, validation and application based on three years of toxicological analyses
PublikacjaBenzodiazepines (BZDs) and Z-drugs have been particularly important treatments for sleeping and anxiety disorders for many years. However, recently, a number of new benzodiazepines (named designer benzodiazepines, DBZDs) were synthesised, but some of them have never been used in the clinic; they reached the black drug market as new psychoactive substances and are used for recreational purposes. The abuse of these substances has...
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Transcriptional profile of in vitro expanded human epidermal progenitor cells for the treatment of non-healing wounds
PublikacjaBackground Epidermal progenitor cells (EPCs) have been under extensive investigation due to their increasing potential of application in medicine and biotechnology. Cultured human EPCs are used in the treatment of chronic wounds and have recently became a target for gene therapy and toxicological studies. One of the challenges in EPCs culture is to provide a high number of undifferentiated, progenitor cells displaying high viability...
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Early Stages of RNA-Mediated Conversion of Human Prions
PublikacjaPrion diseases are characterized by the conversion of prion proteins from a PrPC fold into a disease-causing PrPSC form that is self-replicating. A possible agent to trigger this conversion is polyadenosine RNA, but both mechanism and pathways of the conversion are poorly understood. Using coarse-grained molecular dynamic simulations we study the time evolution of PrPC over 600 μs. We find that both the D178N mutation and interacting...
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Assessing the attractiveness of human face based on machine learning
PublikacjaThe attractiveness of the face plays an important role in everyday life, especially in the modern world where social media and the Internet surround us. In this study, an attempt to assess the attractiveness of a face by machine learning is shown. Attractiveness is determined by three deep models whose sum of predictions is the final score. Two annotated datasets available in the literature are employed for training and testing...
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Human subarachnoid space width oscillations in the resting state
PublikacjaAbnormal cerebrospinal fluid (CSF) pulsatility has been implicated in patients suffering from various diseases, including multiple sclerosis and hypertension. CSF pulsatility results in subarachnoid space (SAS) width changes, which can be measured with near-infrared transillumination backscattering sounding (NIR-T/BSS). The aim of this study was to combine NIR-T/BSS and wavelet analysis methods to characterise the dynamics of the...
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DNA base modifications in chromatin of human cancerous tissues
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GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries
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Human Geomatics in Urban Design—Two Case Studies
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Human capital an analysis for firms from Wielkopolska and Pomorze
PublikacjaRozdział analizuje zasoby ludzkie w Wielkopolsce oraz na Pomorzu, na podstawie danych statystycznych oraz badań empirycznych przeprowadzonych w tych dwóch regionach. Przebadano i opisano zasoby ludzkie w oparciu o liczbę i jakość pracowników w badanych firmach oraz zmiany obu wielkości jakie zaszły w nich w ostatnich latach. Analiza ta jest częścią składową miernika opracowanego przez zespół badawczy, pozwalającego zmierzyć tkankę...
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Language specific spectra generated in the human vocal tract
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Characteristics of sweeteners used in foods and their effects on human health
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Cylindrospermopsin decreases the oxidative burst capacity of human neutrophils
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EBE: elastic blob ensemble for coarse human tracking
PublikacjaProponujemy nowy probabilistyczny algorytm śledzenia oparty na elastycznym zespole kropelkowym (EBE), który ma zastosowanie przy śledzeniu obiektów elastycznych. Wynikiem jest wskazówka nt. zgrubnego ruchu w postaci lokalizacji i orientacji obiektu wraz z lokalizacją kropelki. Głównym założeniem jest to, że orientacja całego obiektu nie zmienia się znacznie między sąsiednimi klatkami. Dyskretna przestrzeń rozwiązań jest tworzona...
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Human Tracking in Multi-camera Visual Surveillance System
PublikacjaArtykuł prezentuje krótkie podsumowanie wykorzystywanych technologii z dziedziny śledzenia osób z wykorzystaniem inteligentnych systemów bezpieczeństwa. Opisane w niniejszym opracowaniu systemy rozpoznawania twarzy, w połączeniu ze śledzeniem osób, nie mają na celu rozpoznawania tożsamości osób. Nie powstaje żadna baza danych łącząca cechy biometryczne z konkretnymi osobami, co sprawia że przestrzegane jest prawo w zakresie ochrony...
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Same but different — Molecular comparison of human KTI12 and PSTK
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Ultrasensitive internally quenched substrates of human cathepsin L
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Human Characters and Morality in Ibn Ḥazm's Philosophical Aphorisms
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The reactions occuring on the implant as a result of contact with human tissue
PublikacjaObecnosc implantu w ciele czlowieka powoduje liczne, czesto nieprzewidywalne skutki. Powodem takiej sytuacji jest duza roznorodnosc interakcji materialu medycznego z kontaktujaca sie z nim tkanka. Stwierdzenie to dotyczy glownie oddzialywan i skutkow zachodzacych na poziomie molekularnym w poszczegolnych komorkach kontaktujacej sie tkanki.
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Human Development and Quality of Institutions in Highly Developed Countries
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Computer Supported Analysis of the Human Body Surface Area
PublikacjaRecent scientific studies show the growing importance of the coefficients: BSA and TBSA, as an alternative to the widely used BMI. The relevant indicators are widely used in medicine, including such areas as: the treatment of burns, chemotherapy, dermatology and toxicology; as benchmarks when calculating doses of drugs and fluids. The particular problems concerning this subject are: the change of the reference parameter value which...
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Editorial: Pharmacology of Plant Polyphenols in Human Health and Diseases
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Human mediated dispersal of cats in the Neolithic Central Europe
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Human-mediated dispersal of cats in the Neolithic Central Europe
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Interictal high-frequency oscillations in focal human epilepsy
PublikacjaPURPOSE OF REVIEW: Localization of focal epileptic brain is critical for successful epilepsy surgery and focal brain stimulation. Despite significant progress, roughly half of all patients undergoing focal surgical resection, and most patients receiving focal electrical stimulation, are not seizure free. There is intense interest in high-frequency oscillations (HFOs) recorded with intracranial electroencephalography as potential...
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Snow Cover Studies: a Review on the Intensity of Human Pressure
PublikacjaSnow cover should be treated as a highly dynamic medium. A variety of physical and chemical processes interact to alter its chemical composition and affect the metamorphism of its individual crystals and layers; this, in turn, has a direct influence on their mutual adhesion, and ultimately on the stability of the entire snow cover. The literature data here reported provide basic information on the forms of solid precipitation,...
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Human friendly architectural design for a small Martian base
PublikacjaW artykule przedstawiono architektoniczny projekt przyjaznej człowiekowi bazy marsjańskiej. Stworzony on został na podstawie analizy warunków na Marsie, dostępnych obecnie technologii i problemów socjopsychologicznych w izolowanych habitatach w warunkach ekstremalnych, a także w odniesieniu do Marsjańskiej Misji Wzorcowej opracowanej przez NASA. Autorzy szczególną uwagę poświęcili czynnikowi ludzkiemu, który nie może zostać zaniedbany...
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Analytical procedures used in examining human urine samples.
PublikacjaŹródłem informacji o stanie środowiska mogą być zarówno wyniki badań próbek części nieożywionej (woda, gleba, powietrze) jak i części biotycznej, w tym także tkanek i płynów ustrojowych człowieka, który jest nieustannie narażony na działanie szerokiego spektrum ksenobiotyków. Badanie płynów ustrojowych człowieka (głównie krwi i moczu) może być bardzo użyteczną i interesującą drogą do uzyskania informacji o stanie środowiska....
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Chitin and derivative chitosan-based structures — Preparation strategies aided by deep eutectic solvents: A review
PublikacjaThe high molecular weight of chitin, as a biopolymer, challenges its extraction due to its insolubility in the solvents. Also, chitosan, as the N-deacetylated form of chitin, can be employed as a primary material for different industries. The low mechanical stability and poor plasticity of chitosan films, as a result of incompatible interaction between chitosan and the used solvent, have limited its industrialization. Deep eutectic...
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Preferred Benchmarking Criteria for Systematic Taxonomy of Embedded Platforms (STEP) in Human System Interaction Systems
PublikacjaThe rate of progress in the field of Artificial Intelligence (AI) and Machine Learning (ML) has significantly increased over the past ten years and continues to accelerate. Since then, AI has made the leap from research case studies to real production ready applications. The significance of this growth cannot be undermined as it catalyzed the very nature of computing. Conventional platforms struggle to achieve greater performance...
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The influence of Nigella sativa essential oil on proliferation, activation, and apoptosis of human T lymphocytes in vitro
PublikacjaIn previous work, we tested the immunomodulatory effect of Nigella sativa (NS) fatty oil. Our results demonstrated that unrefined, obtained by cold pressing black cumin seed oil inhibited lymphocytes’ proliferation and induced their apoptosis in a dose-dependent manner. In this study, we examined the immunomodulatory properties of essential oil (EO) obtained from the NS seeds by hydrodistillation and its two main constituents:...
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Combined analysis of whole human blood parameters by Raman spectroscopy and spectral-domain low-coherence interferometry
PublikacjaIn this article the simultaneous investigation of blood parameters by complementary optical methods, Raman spectroscopy and spectral-domain low-coherence interferometry, is presented. Thus, the mutual relationship between chemical and physical properties may be investigated, because low-coherence interferometry measures optical properties of the investigated object, while Raman spectroscopy gives information about its molecular...
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Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
PublikacjaObjective: Our goal was to analyze the electrophysiological response to direct electrical stimulation (DES) systematically applied at a wide range of parameters and anatomical sites, with particular focus on neural activities associated with memory and cognition. Methods: We used a large set of intracranial EEG (iEEG) recordings with DES from 45 subjects with electrodes...
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A novel in vitro assay for assessing efficacy and toxicity of antifungals using human leukaemic cells infected with Candida albicans
PublikacjaAims: This study describes a novel in vitro assay that simultaneously determines antifungal efficiency and host cell toxicity using suspensions of human leukaemic cells (HL-60) infected with Candida albicans. Methods and Results: The effect of Candida infection on host cell viability was evaluated by the microscopy of trypan blue-stained cells and lactate dehydrogenase (LDH) activity. The in vitro ‘drug potency assay’ utilized...
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Sustainable recovery of plant essential Nitrogen and Phosphorus from human urine using industrial coal fly ash
PublikacjaCoal-based thermal power plants play a pivotal role in meeting global energy demand. The amount of fly ash generated from these plants increases every year, and its successful use has posed a significant environmental risk in the last decade. In this study, coal fly ash was packed in a fixed-bed adsorption column to remove Urea–N from synthetic human urine. To assess the efficacy of fly ash in the removal of Nitrogen, various process...
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Effect of the ionic liquids on extraction of aromatic and sulfur compounds from the model petrochemical stream
PublikacjaSuitability of a imidazolium ionic liquids (ILs) as solvents in dearomatization and desulfurization in the ternary systems and in a model multicomponent systems has been analyzed. With this aim, ternary liquid-liquid phase equilibrium data (LLE) have been obtained for ternary mixtures of {IL + benzene, or toluene, or thiophene, or 2-butanethiol + hexane}, or {IL + benzene + 2-methylpentane} at T = 298.15 K and ambient pressure,...
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Buried Object Characterization by Data-Driven Surrogates and Regression-Enabled Hyperbolic Signature Extraction
PublikacjaThis work addresses artificial-intelligence-based buried object characterization using FDTD-based electromagnetic simulation toolbox of a Ground Penetrating Radar (GPR) to generate B-scan data. In data collection, FDTD-based simulation tool, gprMax is used. The task is to estimate geophysical parameters of a cylindrical shape object of various radii, buried at different positions in the dry soil medium simultaneously and independently...
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Signals Features Extraction in Radioisotope Liquid-Gas Flow Measurements using Autocorrelation Function
PublikacjaKnowledge of the two-phase flow structure is essential for the proper conduct of industrial processes. Description of liquid-gas flow regimes is possible by using of data analysis in time, frequency, or state-space domain. In this research studies, the autocorrelation function is applied for analysis of signals obtained for liquid-gas flow by use gamma-ray absorption. The experiments were carried out on the laboratory hydraulic...
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Web component for automatic extraction of ontological information from informal description of web services
PublikacjaThis article treats about usage possibilities of Web Services and cooperation in development that leads to constant improvement of these components. It describes the semantic methods which can beused to create the description that is comprehensible for computers. It also presents the two models supporting the automatic generation of the semantic description based on informal description. Thepaper draws upon the comparison of two...
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Statistical evaluation of the effectiveness of different extraction techniques for determining robenidyne levels in poultry feed.
PublikacjaPoprzez zastosowanie testu Kruskala-Wallisa i chemometrycznej techniki analizy podobieństwa porównano efektywność sześciu różnych technik ekstrakcji (wytrząsanie, ekstrakcja w aparacie Soxhleta, w aparacie Soxteca, wspomaganej ultradźwiękami, wspomaganej promieniowaniem mikrofalowym oraz przyspieszonej ekstrakcji rozpuszczalnikiem) na podstawie wyników odzysku robenidyny z próbek paszy dla ptaków. W zależności od zastosowanej techniki...
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Optimized procedure of extraction, purification and proteomic analysis of nuclear proteins from mouse brain
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Extraction, Optimization, and Characterization of Neem Seed Oil via Box-Behnken Design Approach
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Transformations of Tetrahydrocannabinol, tetrahydrocannabinolic acid and cannabinol during their extraction from Cannabis sativa L.
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Development and optimization of modified nucleosides and deoxynucleosides simultaneous extraction with the use of Design of Experiments approach
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Development and validation of urinary nucleosides and creatinine assay by capillary electrophoresis with solid phase extraction
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Micro-cloud point extraction for preconcentration of Aspirin in commercial tablets prior to spectrophotometric determination
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Application of a Novel Micro-Cloud Point Extraction for Preconcentration and Spectrophotometric Determination of Azo Dyes
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Micro-Cloud Point Extraction for Preconcentration of Aspirin in Commercial Tablets Prior to Spectrophotometric Determination
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The effect of cabbage juice and it's active components on the protein level and expression of CYP19 in MCF-7 breast cancer cells
PublikacjaWiadomo, że bioaktywne skladniki kapusty mają chemoprewencyjne działanie w przypadku nowotworów piersi, między innymi ze względu na hamowanie aktywności enzymu aromatazy uczestniczącego w biosyntezie estrogenów. Badania prowadzono przy użyciu komórek raka piersi i stwierdzono, że soki z kapusty, zarówno pochodzącej z uprawy ekologicznej jak i przemysłowej, znacząco hamowały ekspresję genu CYP19 kodującego wspomniany enzym. Sugeruje...
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Mass spectrometry-based analysis of therapy-related changes in serum proteome patterns of patients with early-stage breast cancer
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