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Wyniki wyszukiwania dla: BREAST%20CANCER
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Got a Light? Illuminating Lung Cancer
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Photodynamic therapy of cancer with liposomal photosensitizers
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Viruses, cancer and non-self recognition
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The Prognostic Role of CDK9 in Bladder Cancer
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Targeting shelterin proteins for cancer therapy.
PublikacjaAs a global health challenge, cancer prompts continuous exploration for innovative therapies that are also based on new targets. One promising avenue is targeting the shelterin protein complex, a safeguard for telomeres crucial in preventing DNA damage. The role of shelterin in modulating ataxia- telangiectasia mutated (ATM) and ataxia-telangiectasia and Rad3-related (ATR) kinases, key players in the DNA damage response (DDR),...
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Nanomaterials for photothermal and photodynamic cancer therapy
PublikacjaIn recent years, the role of optically sensitive nanomaterials has become powerful moieties in therapeutic techniques and has become particularly emphasized. Currently, by the extraordinary development of nanomaterials in different fields of medicine, they have found new applications. Phototherapy modalities, such as photothermal therapy (PTT) by toxic heat generation and photodynamic therapy (PDT) by reactive oxygen species, are...
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Oxidative modification induced by photodynamic therapy with Photofrin®II and 2-methoxyestradiol in human ovarian clear carcinoma (OvBH-1) and human breast adenocarcinoma (MCF-7) cells
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Profitable areas in large-scale FTTH network optimization
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Contemporary issues in production and utilisation of the common urban areas
PublikacjaThis paper deals with issues in production and utilization of common urban areas within contemporary cities. Therefore, the main focus of it was put on the analysis of the possible models of development of spaces in the context of changing socio-economic environment of cities and evolution of their structure. This issue is discussed also in light of the changing definition of the contemporary public space, which no longer resembles...
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EGNOS-based receiver for precise positionint in restricted areas
PublikacjaPositioning accuracy is very important in many areas. EGNOS improves accuracy, but
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The effects of selected factors on pedestrian crossings in urban areas
PublikacjaPedestrian crossings are designed to help pedestrians cross a road. There are at-grade pedestrian crossings with or without traffic lights and grade separated crossings such as subways and footbridges. Pedestrian crossings may be located next to a junction or on road sections between junctions. Where at-grade crossings are involved, pedestrians and motorists interact, which may lead to dangerous situations and road traffic conflicts....
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METROPOLITAN AREAS IN CENTRAL POLAND AND THEIR IMPACT ON MIGRATION FLOWS
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A risk analysis of winter navigation in Finnish sea areas
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SKYSCRAPER'S PUBLIC AREAS: THE IMPACT ON SPACE AND SOCIAL LIFE
PublikacjaIn recent years, more careful consideration is taken into social issues of designing skyscrapers by humanizing adherent internal and external public areas. Case studies of The Shard (London: 2012), 122 Leadenhall Street (London: 2014), 20 Fenchurch Street (London: 2014), Heron Tower (London: 2011), Tower 25 (Nicosia: 2013), Zoofenster (Berlin: 2012), DNB House (Oslo: 2012), Centrum Biurowe Neptun (Gdansk, 2014), Skytower (Wroclaw:...
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SELECTION OF REFERENCE PLANE BY THE LEAST SQUARES FITTING METHODS
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ORGANIZATIONAL ASPECTS OF THE CONCEPT OF A GREEN CADASTRE FOR RURAL AREAS
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Conversion of Potato Industry Waste into Fodder Yeast Biomass
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Transport undertaking as means of activation of women in rural areas
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VARIOUS PRESENTATION OF NOISE PERCEPTION IN BYDGOSZCZ GREEN AREAS
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Two-dimensional vertical analysis of dam-break flow
PublikacjaW artykule przedstawiono matematyczne modelowanie przepływów ze swobodną powierzchnią w kanałach otwartych. Do symulacji przepływu użyto dwuwymiarowy pionowy model RANS. Wchodzące w skład modelu równania Naviera-Stokesa rozwiązano stosując algorytm SIMPLE dla metody różnic skończonych. Do śledzenia zmian swobodnego zwierciadła wody zastosowano metodę MAC. Analizie poddano szybkozmienny przepływ po poziomym, gładkim dnie wywołany...
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Database systems for tomorrow: new challenges and research areas
PublikacjaZaprezentowano nowe obszary badawcze w dziedzinie baz danych, które będą rozwijane w najbliższej przyszłości. Omówiono takie obszary jak systemy typu ''Plug and Play'', duże systemy sfederowane, nowe architektury systemów baz danych oparte na dużych buforach pamięciowych, integracja danych i aplikacji oraz bazy danych semistrukturalnych.
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Optimization of Bread Production Using Neuro-Fuzzy Modelling
PublikacjaAutomation of food production is an actively researched domain. One of the areas, where automation is still not progressing significantly is bread making. The process still relies on expert knowledge regarding how to react to procedure changes depending on environmental conditions, quality of the ingredients, etc. In this paper, we propose an ANFIS-based model for changing the mixer speed during the kneading process. Although the...
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Massive Open Online Courses: strategies and research areas
PublikacjaThe latest education revolution, the massive open online courses (MOOCs), is gaining momentum, accolades, and participation across industry and academia. These learning laboratory behemoths host and assess tens to hundreds of thousands of students in a single class, for free. Similar to their scope, MOOCs’ short- and long-term educational implications seem massive. Immediate MOOC educational outcomes vary widely from roaring successes...
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Air trapping problem during infiltration on the large areas
PublikacjaThe process of flow modeling in unsaturated porous medium is often found in many fields of sciences: geology, fluid mechanics, thermodynamics, microbiology or chemistry. Problem is relatively complicated due to complexity of the system which contains three phases: water, air and soil skeleton. The flow of water in such a medium can be described using two-phase (2PH) flow formulation, which accounts the inflow of air and water phases,...
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Thematic Areas in the Polish Countryside and Their Role in Local Development
PublikacjaThe article defines the phenomenon of space thematisation with regards to rural areas in Poland. The typology of thematic spaces and criteria of their comparative description have been proposed. Thematic villages, home gardens, amusement parks and housing estates have been distinguished. They have been compared in terms of spatial availability, the degree of user participation and the commercial vs. non-commercial creation purpose....
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Scenario-planning solutions for waterfront flood-prone areas
PublikacjaThe aim of this article is to discuss the potential of applying scenario planning to achieve resilient and future-oriented solutions for flood-prone areas. The authors have proposed additions to scenario-planning processes based on the introduction of research-by-design architectural inquiries. Examined in this article is the insight into the testing of such a modified scenario-planning methodology during two courses that accompanied...
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Arsenic Causing Gallbladder Cancer Disease near the Himalayan bound Rivers in Bihar: A Case study of Gallbladder Cancer
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Legal regulation of direct investment in the United Kingdom and EU countries after Brexit
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The quality management in precast concrete production and delivery processes supported by association analysis
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Clinical studies of detecting COVID-19 from exhaled breath with electronic nose
PublikacjaThe COVID‑19 pandemic has attracted numerous research studies because of its impact on society and the economy. The pandemic has led to progress in the development of diagnostic methods, utilizing the polymerase chain reaction (PCR) as the gold standard for coronavirus SARS‑CoV‑2 detection. Numerous tests can be used at home within 15 min or so but of with lower accuracy than PCR. There is still a need for point‑of‑care tests available...
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A breath of fresh air - social cognitive career theory in studying entrepreneurial intentions
PublikacjaA pinch of robustness and a pinch of freshness create an interesting story. That is why this study focuses on entrepreneurial intentions from an alternative theoretical perspective in an underexplored context. In this paper, it is argued that social cognitive career theory is relevant to the study of individual entrepreneurial cognition and behaviour, and it offers a solid framework in entrepreneurship research. This paper expands...
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The IPV6 Deployment - Best practices
PublikacjaThe new Internet Protocol IPv6 has been regarded for quite a long time as the only option to ensure uninterrupted operation for the Internet service providers andend-users in the current Internet. The article presents important faets about the IPv6, including current statistics of the IPv4 usage, the IPv6 statistics for Poland comparing to the whole Internet. Moreover, this paper shows important aspeets of migration from IPv4 towards...
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Inhibition of cancer antioxidant defense by natural compounds
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Viral Infections and Cancer During Alcohol Use
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EZH2 and SMYD3 expression in papillary thyroid cancer
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Non‐Proteasomal Urine Activity in Bladder Cancer
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Elastolytic activity is associated with inflammation in bladder cancer
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Radiomics and artificial intelligence in lung cancer screening
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Patients’ Awareness Of The Prevention And Treatment Of Colorectal Cancer*
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Autoimmunity and Cancer—Two Sides of the Same Coin
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Arsenic causing gallbladder cancer disease in Bihar
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Catalytic topoisomerase II inhibitors in cancer therapy.
PublikacjaDNA topoizomeraza II jest jednym z głównych celów molekularnych dla leków stosowanych w terapii przeciwnowotworowej. Wszystkie inhibitory tego enzymu są zdolne do zakłócania w jeden z etapów cyklu katalitycznego topoizomerazy II. Związki, które stabilizują kowalencyjny kompleks DNa i topoizomerazy II (znany jako kompleks rozszczepialny) są nazywane truciznami topoizomerazy, inne związki, które hamują aktywność enzymu na innych...
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Diagnostic Accuracy of Liquid Biopsy in Endometrial Cancer
PublikacjaBackground: Liquid biopsy is a minimally invasive collection of a patient body fluid sample. In oncology, they offer several advantages compared to traditional tissue biopsies. However, the potential of this method in endometrial cancer (EC) remains poorly explored. We studied the utility of tumor educated platelets (TEPs) and circulating tumor DNA (ctDNA) for preoperative EC diagnosis, including histology determination. Methods:...
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Metal–Organic Frameworks (MOFs) for Cancer Therapy
PublikacjaMOFs exhibit inherent extraordinary features for diverse applications ranging from catalysis, storage, and optics to chemosensory and biomedical science and technology. Several procedures including solvothermal, hydrothermal, mechanochemical, electrochemical, and ultrasound techniques have been used to synthesize MOFs with tailored features. A continued attempt has also been directed towards functionalizing MOFs via “post-synthetic...
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Soil contamination with geohelminths in children’s play areas in Szczecin, Poland
PublikacjaThe presence of invasive forms of parasites in the soil represents a potential threat to public health, especially for children. The aim of the study was to determine the degree of contamination with geohelminth eggs of soil samples collected from sandpits and playgrounds in the Szczecin area. The findings showed overall prevalence of soil samples contaminated with geohelminth eggs in the soil and sand...
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EGNOS-based GNSS receiver for precise positioning in restricted areas
PublikacjaPositioning accuracy is very important in many areas, whereas the typical GPS receiver accuracy is often not sufficient. The European Geostationary Navigation Overlay Service (EGNOS), Europe’s first venture into satellite navigation, improves the open public service offered by the Global Positioning System (GPS). As a satellite navigation augmentation system, EGNOS improves the accuracy of GPS by providing a positioning accuracy...
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Modeling the global atmospheric transport and deposition of mercury to the Great Lakes
PublikacjaMercury contamination in the Great Lakes continues to have important public health and wildlife ecotoxicology impacts, and atmospheric deposition is a significant ongoing loading pathway. The objective of this study was to estimate the amount and source-attribution for atmospheric mercury deposition to each lake, information needed to prioritize amelioration efforts. A new global, Eulerian version of the HYSPLIT-Hg model was used...
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Treatment Wetlands in Rural Areas of Poland for Baltic Sea Protection
PublikacjaWater and wastewater management, especially in rural areas, greatly affects loads of nutrients discharged to the Baltic Sea. In Poland, this management is unbalanced because of the dispersed development and in many locations construction of sewerage system is uneconomic or even impossible. For this reason, a significant part of sewage from single-family houses in rural areas must be discharged into domestic sewage systems. The...
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Automatic road traffic safety management system in urban areas
PublikacjaTraffic incidents and accidents contribute to decreasing levels of transport system reliability and safety. Traffic management and emergency systems on the road, using, among others, automatic detection, video surveillance, communication technologies and institutional solutions improve the organization of the work of various departments involved in traffic and safety management. Automation of incident management helps to reduce...
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Ranking ecosystem services delivered by trees in urban and rural areas
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