Wyniki wyszukiwania dla: LOW-PROFILE
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Modulation of CYP1A1, CYP1A2 and CYP1B1 expression by cabbage juices and indoles in human breast cell lines
PublikacjaEpidemiological studies have shown that consumption of cab- bage and sauerkraut is connected with significant reduction of breast cancer incidences. Estrogens are considered a major breast cancer risk factor and their metabolism by P450 enzymes substan- tially contributes to carcinogenic activity. The aim of this study was to investigate the effect of cabbage and sauerkraut juices of differ- ent origin on the expression profile...
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The competitive advantage of Ppomorskie Voivodeship in strategic documents based on the Regional Innovation Strategy
PublikacjaThe article presents and discusses the main assumptions and courses of action contained in the innovation strategy for Pomorskie voivodeship with respect to building the competitive advantage The considerations are preceded by analyses concerning the interpretation and meaning of the following concepts in contemporary economy (with special emphasis on their regional context): competitiveness, competitive advantage and innovation,...
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The competitive advantage of Pomorskie Voivodeship in strategic documents based on the Regional Innovation Strategy
PublikacjaThe article presents and discusses the main assumptions and courses of action contained in the innovation strategy for Pomorskie voivodeship with respect to building the competitive advantage The considerations are preceded by analyses concerning the interpretation and meaning of the following concepts in contemporary economy (with special emphasis on their regional context): competitiveness, competitive advantage and innovation,...
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The speciation of selected heavy metals in sewage sludge stabilized in reed basins
PublikacjaThe aim of the work was to determine influence of time on organic matter content, nutrients concentrations as well as speciation of selected heavy metals (Cd, Pb, Ni, Cr, Cu and Zn) in sewage sludge stabilized in reed basins during 7-15 years. The analyzed sewage sludge was collected from reed basins from four municipal WWTPs located in Denmark serving from 9 000 to 40 000 pe in Vallo, Rudkøbing, Nakskov and Helsinge. Sewage...
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Badania nośności na zginanie innowacyjnego kształtownika giętego na zimno typu GEB
PublikacjaLekkie konstrukcje metalowe wytwarzane z kształtowników giętych na zimno to jedna z najszybciej rozwijających się dyscyplin w zakresie budownictwa. Do niedawna profile gięte na zimno stosowano wyłącznie jako elementy drugorzędne, czyli płatwie oraz rygle. Nowo opatentowany przekrój typu GEB ma być wykorzystywany jako element nośny konstrukcji ramowych. Jednak jego zaistnienie na rynku budowlanych konstrukcji metalowych jest uwarunkowane...
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Oxidation and hydrogen behavior in Zr-2Mn alloy
PublikacjaThe purpose of the present research was to determine the oxidation and hydrogenation behavior in the new Zr-2Mn alloy. The oxidation of alloy was performed at temperatures between 350°C and 900°C for 30 minutes. The hydrogen charging was made for 72 h at a current density 80 mA/cm2. The charged samples were heat treated at 400°C for 4 h to obtain a uniform hydrogen profile content across the sample. The oxidation resulted in an...
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Numerical investigation on dynamic response of a steel lattice tower under various seismic events
PublikacjaThe present paper presents the results of the numerical study designed to investigate the soil-structure flexibility effects on modal parameters (i.e. fundamental frequencies) and time-history analysis response (represented by the top relative displacements) of a 46.8 m high steel lattice tower subjected to a number of ground motions including also one mining tremor. In addition to the fixed-base condition, three different soil...
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Sources of inspiration in designing ecological buildings. If not Pinterest than what?
PublikacjaEfficiency of ecological measures for sustainable architecture depends greatly upon the moment in which it is defined as essential, and how early it can be applied during the design concept stage. The following article refers to inspiration, the initial stage of the design and means to combine it with substantial knowledge regarding ecological architecture. Means, such as computer programs...
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Real-time monitoring of the emission of volatile organic compounds from polylactide 3D printing filaments
PublikacjaEstablishing the emission profile of volatile organic compounds generated during fused deposition modeling 3D printing using polymer filaments is important in terms of both understanding the processes taking place during thermal degradation of thermoplastics, and assessing the user's exposure to potentially harmful volatiles. However, obtaining detailed, real-time qualitative and quantitative results poses a challenge. In this...
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Evaluation of high-frequency roughness measurement errors for composite and ceramic surfaces after machining
PublikacjaPrecise characterisation of surface topography is of the greatest importance since many factors directly affect the accuracy of the whole measurement process. In this paper, the variety of surface topographies from machined composite and ceramic workpieces was studied with a special emphasis on the measurement results. Surfaces were subjected to the ground diamond, honing and milling processes. Measurement results were analysed...
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Arching of railway turnouts by analytical design method
PublikacjaThe paper involved the issue of arching of the railway turnouts. This is an issue which is given relatively less attention to scientific and research activities. Reference has been made to the book by Wladyslaw Rzepka, under the title „Curved turnouts in plan and profile”, which has been used in Poland for more than 50 years as the main source of information relating to the turnouts on the curve. The book is a compilation of elaborations...
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Non-conventional approach in single-sided lapping process: kinematic analysis and parameters optimization
PublikacjaThe lapping process is strongly affected by a number of input parameters. One of the fundamental mechanical processes in lapping is the abrasive effect of particles. In order to examine the influence of the kinematic parameters on the lapping uniformity of unconventional single-sided machine, numerical simulations of particles sliding trajectories are performed. Changing the kinematic parameters, e.g., rotational velocities or...
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The Toolbox of Methods for Multidirectional Characterization of Dietary Nucleic Acids; Verification for Raw and Processed Food Products
PublikacjaCurrently, the nutritional value of food is associated mainly with components such as proteins, carbohydrates, and lipids. However, another important macromolecules present in many foods are dietary nucleic acids (dietNA), i.e., DNA as well as both coding and non-coding RNAs. In the context of food chemistry and nutrition, dietNA are nowadays vastly neglected. In consequence, there are no dedicated methodologies to characterize...
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ATTITUDE OF YOUTH TO SELECT SPECIALTY AND QUALITY OF EDUCATION
PublikacjaThe problems of young people guidance on the choice of profession according to the labour market requirements and the education quality are considered. The problem of youth education and employment is very topical, and in relation to vocational education the main theoretical and practical approaches to its modernization should be changed. The paper is determined the key aspects for choosing the University to receive education and...
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A new assay for the simultaneous identification and differentiation of Klebsiella oxytoca strains.
PublikacjaKlebsiella oxytoca is the second most frequently identified species of Klebsiella isolated from hospitalized patients. Klebsiella spp. is difficult to identify using conventional methods and is often misclassified in clinical microbiology laboratories. K. oxytoca is responsible for an increasing number of multi-resistant infections in hospitals because of insufficient detection and identification. In this study, we propose a new...
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Multicriteria Optimization Approach to Design and Operation of District Heating Supply System over its Life Cycle
PublikacjaDistrict Heating (DH) systems are commonly supplied using local heat sources. Nowadays, modern insulation materials allow for effective and economically viable heat transportation over long distances (over 20 km). In the paper a method for optimized selection of design and operating parameters of long distance Heat Transportation System (HTS) is proposed. The method allows for evaluation of feasibility and effectivity of heat transportation...
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Study of microstress state of P91 steel using complementary mechanical Barkhausen, magnetoacoustic emission, and X-ray diffraction techniques
PublikacjaThe paper deals with assessment of microstress state of martensite P91 steel using three complementary techniques: mechanical Barkhausen emission, magnetoacoustic emission (MAE), and X-ray diffraction (XRD) profile analysis. Magnetic coercivity Hc and microstructure were investigated with inductive magnetometry and magnetic force microscopy (MFM), respectively. Internal stress level of P91 steel was modified by heat treatment....
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INVESTIGATION OF THE EFFECT OF THE ROCKET'S SUBORBITAL FLIGHT ON BIOFILM, ENZYMES AND BIOSYNTHESIS ON AUTONOMOUS, MODULAR AND SCALABLE PLATFORM FOR CONDUCTING EXPERIMENTS OF AN ASTROBIOTECHNOLOGICAL NATURE
PublikacjaWith new incentives for human space exploration, biotechnological experiments in orbit became imperative.Answering this need, we build an autonomous, modular, and scalable platform that enables those experiments onrockets. We called it AMBER. The aim of the payload of the R6 suborbital rocket is to perform an experiment tostudy the influence of rocket flights on biofilm, molecular...
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Soil and groundwater fecal contamination as a result of sewage sludge land application.
PublikacjaThe release of sludge-born bacteria and their further transport in subsurface was studied. The migration of bacteria was investigated in column experiments which were carried out under the conditions corresponding to naturally occurring extreme rainfall. Coal fly ash as well as coarse and medium grained sand, which properties are similar to the soils present in degraded areas, were used as column beds. Sewage sludge was applied...
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Permeability of the small intestinal mucus for physiologically relevant studies: Impact of mucus location and ex vivo treatment
PublikacjaThe small intestinal mucus is a complex colloidal system that coats the intestinal mucosa. It allows passage on nutrients/pharmaceuticals from the gut lumen towards the epithelium, whilst preventing it from direct contact with luminal microorganisms. Mucus collected from intestinal tissue is often used in studies looking at inter-mucosal transport of food particulates, drug carriers, etc. However, detaching the highly hydrated...
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Analytical design method for widening the intertrack space
PublikacjaThe paper involved the issue of arching of the railway turnouts. This is an issue which is given relatively less attention to scientific and research activities. Reference has been made to the book by Wladyslaw Rzepka, under the title „Curved turnouts in plan and profile”, which has been used in Poland for more than 50 years as the main source of information relating to the turnouts on the curve. The book is a compilation of elaborations...
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Understanding the early-stage release of volatile organic compounds from rapeseed oil during deep-frying of tubers by targeted and omics-inspired approaches using PTR-MS and gas chromatography
PublikacjaDuring deep-frying, a plethora of volatile products is emitted with the fumes. These compounds could act as oil quality indicators and change the indoor air composition leading to health risks for occupants. The presented experiments focus on deep-frying of different tubers in rapeseed oil at different frying temperatures. Here, two scenarios for real-time monitoring of volatile organic compounds (VOCs) using proton transfer reaction...
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pH-Responsive Drug Delivery Nanoplatforms as Smart Carriers of Unsymmetrical Bisacridines for Targeted Cancer Therapy
PublikacjaSelective therapy and controlled drug release at an intracellular level remain key challenges for effective cancer treatment. Here, we employed folic acid (FA) as a self-navigating molecule in nanoconjugates containing quantum dots (QDs) and β-cyclodextrin (β-CD) for the delivery of antitumor unsymmetrical bisacridine compound (C-2028) to lung and prostate cancers as well as normal cells. The bisacridine derivative can form the...
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Static Shunt PE Voltage-Quality Controllers
PublikacjaThis chapter focuses on power electronics (PE)-based solutions used in distribution networks for reduction of supply-voltage-quality deterioration, from long interruptions to the harmonics. Various PE devices and their combinations are addressed for particular or a range of voltage disturbances. A particular solution is applied taking into account demands for voltage quality and network configuration. In general, there are three...
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Phytochemical screening and biological evaluation of Greek sage (Salvia fruticosa Mill.) extracts
PublikacjaThis study explores the influence of extraction solvents on the composition and bioactivity of Salvia fruticosa extracts. Ultrasound-assisted extraction with water, ethanol and their mixtures in variable proportions was used to produce four different extracts. An untargeted UPLC/MS‑based metabolomics was performed to discover metabolites profile variation between the extracts. In the analyzed samples, 2704 features had been detected,...
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Education Towards The Use Of BIM On The Example Of Polish Universities
PublikacjaBIM (Building Information Modeling) has been one of the rapidly developing fields of digital techniques supporting the realization of construction projects in recent years. Further development, and especially the use of these techniques, depends to a large extent on the qualifications of young construction engineers who start their professional careers in this field. The article attempts to synthetically list and compare subjects,...
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Physicochemical and Volatile Compounds Analysis of Fruit Wines Fermented with Saccharomyces cerevisiae: FTIR and Microscopy Study with Focus on Anti-Inflammatory Potential
PublikacjaThe growing trend in fruit wine production reflects consumers’ interest in novel, diverse drinking experiences and the increasing demand for healthier beverage options. Fruit wines made from kiwi, pomegranates, and persimmons fermented using S. bayanus Lalvin strain EC1118 demonstrate the versatility of winemaking techniques. Kiwifruit, persimmon, and pomegranate wines were analyzed using HPLC and GC-TOFMS analyses to determine...
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Deterministic versus stochastic modelling of unsaturated flow in a sandy field soil based on dual tracer breakthrough data
PublikacjaThe 216 km2 Neuenhagen Millcreeck catchment can be characterized as a drought sensitive landscape in NE Germany. It is therefore a fundamental human interest to understand how water that fell as precipitation moves through the unsaturated soils and recharges groundwater. Additionally, a better knowledge of nutrient transport from soil to groundwater is important also, especially in landscapes with light sandy soils. For a better...
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Decision support system for design of long distance heat transportation system
PublikacjaDistrict Heating (DH) systems are commonly supplied using local heat sources. Nowadays, modern insulation materials allow for effective and economically viable heat transportation over long distances (over 20 km). The paper proposes a Decision Support System (DSS) for optimized selection of design and operating parameters of a long distance Heat Transportation System (HTS). The method allows for evaluation of feasibility and effectiveness...
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Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells
PublikacjaAdipose-derived stem cells (ASCs) have become an important research model in regenerative medicine. However, there are controversies regarding the impact of prolonged cell culture on the ASCs phenotype and their differentiation potential. Hence, we studied 10 clinical ASCs replicates from plastic and oncological surgery patients, in six-passage FBS supplemented cultures. We quantified basic mesenchymal cell surface marker transcripts...
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Phase I and phase II metabolism simulation of antitumor-active 2-hydroxyacridinone with electrochemistry coupled on-line with mass spectrometry.
PublikacjaHere, we report the metabolic profile and the results of associated metabolic studies of 2-hydroxyacridinone (2-OH-AC), the reference compound for antitumor-active imidazo- and triazoloacridinones. Electrochemistry coupled with mass spectrometry was applied to simulate the general oxidative metabolism of 2-OH-AC for the first time. The reactivity of 2-OH-AC products to biomolecules was also examined. The usefulness of the electrochemistry...
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Comparative Lipidomic Study of Human Milk from Different Lactation Stages and Milk Formulas
PublikacjaIn this report, we present a detailed comparison of the lipid composition of human milk (HM) and formula milk (FM) targeting different lactation stages and infant age range. We studied HM samples collected from 26 Polish mothers from colostrum to 19 months of lactation, along with FM from seven brands available on the Polish market (infant formula, follow-on formula and growing-up formula). Lipid extracts were analysed using liquid...
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Thermal and Hydrodynamic Phenomena in the Stagnation Zone — Impact of the Inlet Turbulence Characteristics on the Numerical Analyses
PublikacjaOne of the methods of heat transfer enhancement is utilization of the turbulent impinging jets, which were recently applied, for example, in the heat exchangers. Their positive impact on the heat transfer performance was proven, but many questions related to the origin of this impact are still unanswered. In general, the wall-jet interaction and the near-wall turbulence are supposed to be its main reason, but their accurate numerical...
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Modeling of lapping plate wear and conditioning in single-sided lapping
PublikacjaIn order to achieve higher quality on worked surfaces with lower roughness, very high accuracy of shape and dimensions it is crucial to improve conventional finishing technologies and to develop new working principles. Single-sided lapping is one of the most effective planarization technologies and it is determined by a number of factors and boundary conditions. The most significant influence over a dimensional and profile accuracy,...
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Molecular basis and potential activity of HIV-1 reverse transcriptase toward trimethylamine-based compounds
PublikacjaReverse transcriptase (RT) inhibitors are currently used to treat human immunodeficiency virus (HIV)-1 infections. In this work, novel triethylamine derivatives were designed and studied by rigid and flexible docking and molecular dynamics (MD) approaches. An apo form of HIV-1 RT was also studied by MD simulation to analyze comparative response of protein in ligand-bound and ligand-unbound forms. Among newly designed HIV-1 RT inhibitors,...
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Efficiency of thermomechanical reclaiming of ground tire rubber conducted in counter-rotating and co-rotating twin screw extruder
PublikacjaIn this article the results of research on a continuous thermomechanical reclaiming process of ground tire rubber (GTR) conducted in a twin screw extruder are presented. The effects of the rotation direction (co-rotating/counter-rotating), design of co-rotating plasticizing units and the rotational speed of the screws on the extruder working parameters, sol fraction and the degree of reclaiming in the obtained products were described....
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Colour Terms in Five Linguistic Images of the World: The Semantic Perspective
PublikacjaSocial and cultural factors shape the linguistic perception of colour. At the same time, colour terms co-create the linguistic image of the world, which allows us to interpret reality and profile our statements and beliefs. This paper presents six basic colour terms: white, black, red, green, yellow, and blue (both as adjectives and as nouns) in the five different linguistic images of the world of the following languages: English,...
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Analiza osadów dennych pod kątem ich właściwości nawozowych
PublikacjaThe analysis of bottom sediments in terms of their fertilizing properties. In paper the characterize of sediments as product to nature usage was done. Analyzed material was taken from ecological treatment system located in wastewater treatment plant in Swarzewo (Pomerania Region) about flow Q= 6000 m3/d. Measurements of dry matter and organic matter content, as well as nitrogen concentrations and phosphorus fractions: loosely...
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Algorithm for Automatic Wear Estimation of Railway Contact Strips Based on 3D Scanning Results
PublikacjaElectric rail vehicles use current collection system which consists of overhead contact line and a current collector (pantograph) mounted on the roof of a vehicle. A pantograph is equipped with contact strips, which slide along the contact wire, ensuring steady electric contact. Contact strips are made of carbon layer, fixed to an aluminum carrier. The carbon layer wears down due to friction. Using overly worn contact strips increases...
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Large hydrodynamic thrust bearing: Comparison of the calculations and measurements
PublikacjaHydrodynamic thrust bearings, used to carry axial loads in heavily loaded shafts of water power plants hydro turbines, can reach outer diameters even exceeding 5 m. In such large objects scale effect could be observed. According to this, allowable bearing specific load assuring safe operation of the bearings has to be decreased, which increases thrust bearing dimensions. This effect is caused by excessive thermal deflections of...
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Medical-Grade PCL Based Polyurethane System for FDM 3D Printing—Characterization and Fabrication
PublikacjaThe widespread use of three-dimensional (3D) printing technologies in medicine has contributed to the increased demand for 3D printing materials. In addition, new printing materials that are appearing in the industry do not provide a detailed material characterization. In this paper, we present the synthesis and characterization of polycaprolactone (PCL) based medical-grade thermoplastic polyurethanes, which are suitable for forming...
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BODIPY‐Perylene Charge Transfer Compounds; Sensitizers for Triplet‐Triplet Annihilation Up‐conversion
PublikacjaBODIPY heterochromophores, asymmetrically substituted with perylene and/or iodine at the 2 and 6 positions were prepared and investigated as sensitizers for triplet-triplet annihilation up conversion (TTA-UC). Single-crystal X-ray crystallographic analyses show that the torsion angle between BODIPY and perylene units lie between 73.54 and 74.51, though they are not orthogonal. Both compounds show intense, charge transfer absorption...
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Mineral Composition of Dietary Supplements-Analytical and Chemometric Approach
PublikacjaThere is a lack of data on the actual composition and effectiveness of beetroot-based dietary supplements. The research aimed to determine the profile of 22 elements (Na, K, Ca, Mg, P, Fe, As, Se, Zn, Cu, Ag, Co, Ni, Mo, Al, Mn, Sr, Cr, Ba, Li, Pb, Cd) in beetroot and its supplements by the microwave plasma atomic emission spectrometry (MP-AES) method. The analytical procedure was optimised and validated. The composition of both...
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Significant Production of Thermal Energy in Partially Ionized Hyperbolic Tangent Material Based on Ternary Hybrid Nanomaterials
PublikacjaNanoparticles are frequently used to enhance the thermal performance of numerous materials. This study has many practical applications for activities that have to minimize losses of energy due to several impacts. This study investigates the inclusion of ternary hybrid nanoparticles in a partially ionized hyperbolic tangent liquid passed over a stretched melting surface. The fluid motion equation is presented by considering the...
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A novel approach for processing CaAlSiON glass-ceramics by spark plasma sintering: Mechanical and electrical properties
PublikacjaLithium containing glassy materials can be used as solid electrolytes or electrode materials for lithium-ion batteries due to their high energy density. Conventional melt-quenched Ca11Al14Si16O49N10 glass powder containing 24 e/o N, doped with Li-ions (1, 3, and 6 wt. %) and sintered by spark plasma sintering technique (SPS) was studied. The benefits of using SPS to produce glass-ceramics are rapid heating rates compared to conventional...
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System oceny efektywności użytkowania aparatów słuchowych
PublikacjaCelem rozprawy jest opracowanie metody oceny efektywności protezowania słuchu przy użyciu aparatów słuchowych, która pozwoli w łatwy sposób poddawać ocenie korzyść z użytkowania protez słuchowych w najbardziej typowych sytuacjach akustycznych. Przedstawiono genezę podjętych badań i na tej podstawie zaproponowano cele i tezy rozprawy doktorskiej. W pracy w pierwszej kolejności zawarto przegląd dotyczący rodzajów ubytku słuchu i...
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Combining X-ray tomogrpahy imaging and DEM simulations to investigate granular material flow during silo discharging
PublikacjaEven after few decades of research, the study of particle motion taking place during silo discharging hasn’t been fully addressed, both experimentally and numerically, because of nontrivial behaviors that occur during associated flow patterns. For instance, discrete element method (DEM) has shown good qualitative prediction potential of velocity profile, but, on the other hand, frequently failed to match quantitatively experimental...
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The Education of Analytical Chemists in Polish Universities
PublikacjaAnalytical Chemistry plays a very important role in the modern world. The main reasons are; the need of environmental monitoring, quality of food and water control, human health, quality of industrial production control, nanotechnologies and material science. Together with Inorganic Chemistry, Organic Chemistry and Physical Chemistry, Analytical Chemistry is a fundamental chemical course. The education of Analytical Chemists is...
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Experimental Investigations on the Influence of Coil Arrangement on Melting/Solidification Processes
PublikacjaThe latent heat thermal energy storage units are very popular because of their high energy density and almost close to constant temperature during the charging/discharging. In the present study has been proposed new shell-and-coil geometry with a shifted coil position to enhance the performance of phase change thermal magazine. The experimental investigations have been performed both for the melting and solidification process of...
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Development and evaluation of thermosensitive hydrogels with binary mixture of Scutellariae baicalensis radix extract and chitosan for periodontal diseases treatment.
PublikacjaScutellaria baicalensis root displays anti-inflammatory and antibacterial properties due to the presence of flavonoids, particularly baicalin, baicalein, and wogonin. Our work aimed at developing thermosensitive hydrogels containing a binary mixture of S. baicalensis radix lyophilized extract and chitosan as a novel approach for periodontal diseases treatment....