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Wyniki wyszukiwania dla: ACTIVE%20SONAR
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Modulation of CYP19 expression by cabbage juices and their active components: indole-3-carbinol and 3,30-diindolylmethene in human breast epithelial cell lines
PublikacjaThe aim of this study was to evaluate the effect of white cabbage and sauerkraut juices of different origin and indole-3-carbinol (I3C) and diindolylmethane (DIM) on expression of CYP19 gene encoding aromatase, the key enzyme of estrogen synthesis.Remarkable differences in the effect on CYP19 transcript and protein level were found between the cab- bage juices (in 2.5-25 mL/L concentrations) and indoles (in 2.5-50 lM doses) in...
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Piotr Lorens prof. dr hab. inż. arch.
OsobyPiotr Lorens – prof. dr hab. inż. arch., prof. nzw. Politechniki Gdańskiej. Po ukończeniu studiów w 1994 roku podjął pracę w Zakładzie Rozwoju Miasta na Wydziale Architektury Politechniki Gdańskiej. Uzyskawszy Stypendium Fulbrighta wyjechał na staż do USA, gdzie w latach 1996-1997 ukończył Special Program for Urban and Regional Studies na Massachusetts Institute of Technology oraz International Training Program na Harvard University...
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NAIS-Native American and Indigenous Studies Association
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A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells
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Reactive deposition of TiNx layers in a DC-magnetron discharge
PublikacjaTiNx layers have been deposited in 'balanced mode' and 'unbalanced mode' of a reactive DC-magnetron plasma (carrier gas argon, reactive gas nitrogen) under different conditions. Discharge power and reactive gas flow have been varied. The layers have been examined by X-ray photoelectron spectroscopy (XPS), X-ray reflectometry (XR), and spectroscopic ellipsometry (SE). The results of the layer analyses were combined with plasma investigations...
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Glucocorticoids Inhibit Wound Healing: Novel Mechanism of Action
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Amphotericin B and Its New Derivatives - Mode of Action
PublikacjaAmphotericin B (AmB) is a well known antifungal and antiprotozoal antibiotic used in the clinic for several decades. Clinicalapplications of AmB, however, are limited by its nephrotoxicity and many other acute side effects which are not acceptable by patientswhen their life is not threaten. In order to improve the therapeutic index of this drug, lipid formulations have been introduced and manyefforts have been made to obtain less...
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Game-based Sprint retrospectives: multiple action research
PublikacjaIn today’s fast-paced world of rapid technological change, software development teams need to constantly revise their work practices. Not surprisingly, regular reflection on how to become more effective is perceived as one of the most important principles of Agile Software Development. Nevertheless, running an effective and enjoyable retrospective meeting is still a challenge in real environments. As reported by several studies,...
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Chemometric methods for determination of mechanisms of action of anticancer compounds
PublikacjaW 1990 amerykański Narodowy Instytut Raka (NCI) wprowadził szeroki test przesiewowy in vitro mający na celu poszukiwanie nowych związków przeciwnowotworowych. Test został wdrożony po przebadaniu 171 standardowych związków przeciwnowotworowych. Przedmiotem niniejszej pracy jest próba stworzenia reguł klasyfikacji związków standardowych ze względu na ich mechanizm działania przeciwnowotworowego na podstawie wyników z testu NCI. Potwierdzono...
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Degree product formula in the case of a finite group action
PublikacjaLet V, W be finite dimensional orthogonal representations of a finite group G. The equivariant degree with values in the Burnside ring of G has been studied extensively by many authors. We present a short proof of the degree product formula for local equivariant maps on V and W.
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Action-reaction based synthesis of acoustic wavefield equations
PublikacjaThe analysis of acoustic fields is usually based on the well-known mathematics of second order partial differential equations called wave equations. The author explores the duality and symmetry of linear fluid mechanics and develops two distinct equations of acoustics on the basis of a causal approach to local small-scale phenomena. Wavefields that are solutions of these equations have different composition, the spherical pressure...
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The mechanism of grouting action under the base of bored pile
PublikacjaThe grouting under the base of bored pile is carried out in order to reduce pile settlement and improve its bearing capacity. The principal aim of grouting is to introduce an initial force between the soil and the pile base. In non-cohesive soil, the grouting can also enlarge the pile base area and therefore improve the base resistance. The example of static load tests on instrumented bored piles installed with and without grouting...
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New approach to localization of clicks in archive speech signals.
PublikacjaPrzedstawiono problem lokalizacji zniekształceń impulsowych w archiwalnych sygnałach mowy. Pokazano, że detekcja oparta na dwuzakresowym modelu autoregresyjnym i przetwarzanie dwukierunkowe pozwala uzyskać znaczącą poprawę działania w stosunku do istniejących metod lokalizacji zniekształceń.
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Music Archive Metadata Processing Based on Flow Graphs.
PublikacjaW referacie zaproponowano metodykę wyszukiwania informacji muzycznej w bazach internetowych w oparciu o meta opis. Skonstruowany algorytm wykorzystuje grafy przepływowe Pawlaka.
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Decomposition of the wall force acting on the single bubble motion.
PublikacjaW referacie skupiono uwagę na rozkładzie siły hydrodynamicznej działającej na kulę (uproszczony model pęcherzyka) na kierunku prostopadłym do ścianki kanału. Pokazano stanowisko badawcze, omówiono procedurę pomiarową oraz zamiszczono przykładowe wyniki badań eksperymentalnych i modelowania matematycznego.
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Octave Error Immune and Instantaneous Pitch Detection Algorithm.
PublikacjaCelem publikacji jest prezentacja odpornego na błędy oktawowe, bazującego na analizie widmowej algorytmu detekcji częstotliwości podstawowej. Zaproponowana metoda dobrze sobie radzi z sygnałami o dużej zawartości sygnałów harmonicznych, jak i z prawie sinusoidalnymi przebiegami. Eksperymenty przeprowadzonno na 567 dzwiękach instrumentów muzycznych. Dźwięki grane były z różnymi artykulacjami, dynamiką i reprezentowałe były w całej...
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Tailoring Graphene to Achieve Negative Poisson's Ratio Properties
PublikacjaGraphene can be made auxetic through the introduction of vacancy defects. This results in the thinnest negative Poisson's ratio material at ambient conditions known so far, an effect achieved via a nanoscale de-wrinkling mechanism that mimics the behavior at the macroscale exhibited by a crumpled sheet of paper when stretched.
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Antecedents to Achieve Kanban Optimum Benefits in Software Companies
PublikacjaIn 2004, Kanban successfully entered into the Agile and Lean realm. Since then software companies have been increasingly using it in software development teams. The goal of this study is to perform an empirical investigation on antecedents considered as important for achieving optimum benefits of Kanban use and to discuss the practical implications of the findings. We conducted an online survey with software professionals from...
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Multistatic sonar for man-made lakes and water-power plants antiterrroristic protection
PublikacjaArtykuł opisuje nową koncepcję dopplerowskiego sonaru multistatycznego opracowanego w Katedrze Systemów Elektroniki Morskiej Politechniki Gdańskiej. System składa się z sieci hydrofonów rozmieszczonych równomiernie w obserwowanym akwenie oraz ze źródła dźwięku w postaci fali ciągłej o stałej częstotliwości i bardzo niskim natężeniu. Dzięki zastosowaniu specjalnie opracowanych algorytmów przetwarzania sygnałów uzyskuje się poprawną...
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Seafloor characterisation using multibeam sonar echo signal processing and image analysis
PublikacjaThe authors propose the approach to multibeam seafloor characterisation which relies on the combined, concurrent use of two different techniques of multibeam sonar data processing. The first one is based on constructing the grey-level sonar images of seabed using the echoes received in the consecutive beams. Then, the parameters describing the local region of sonar image, namely, the local standard deviation of a grey level, and...
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Analysis of distance measurement errors in CW FM sonar with MLS code modulation
PublikacjaAlthough used in the classic silent sonar, the CW FM sounding signal has a major flaw which is its inaccuracy in determining the distance to a target. The authors of the article have developed a concept of silent sonar using frequency modulation signals switched by pseudorandom codes, already discussed in their previous work. This article presents a detailed analysis of errors in CW FM sonar with pseudo-random sequence code modulation...
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Combined method of multibeam sonar signal processing and image analysis for seafloor classification
PublikacjaThe combined approach to seafloor characterisation was investigated. It relies on calculation of several descriptors (parameters) related to seabed type using three types of multibeam sonar data obtained during seafloor sensing: 1) the grey-level sonar images (echograms) of seabed, 2) the 3D model of the seabed surface which consists of bathymetric data, 3) the set of time domain bottom echo envelopes received in the consecutive...
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Kalman filtering for 3d real time data visualisation of multibeam sonar records.
PublikacjaPrzedstawiono zastosowanie filtracji Kalmana do korekcji błędów systematycznych występujących w danych pochodzących z systemu wielozwiązkowego. Zaproponowano dwuetapową filtrację danych dla każdego wachlarza danych, która realizowana jest w czasie rzeczywistym. Zaprezentowano rezultaty wizualizacji dna morskiego przed i po filtracji.
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Safety enhancement using 3D multibeam sonar imaging in shallow waters areas
PublikacjaSonary wielowiazkowe wykorzystanee byc moga do poprawy bezpieczenstwa zeglugi na obszarach wod plytkich. Dzieki istotnej poprawie rozdzielczosci horyzontalnej i wertykalnej pomiarow zastosowane byc moga do obrazowania wod plytkich szczegolnie niebezpiecznych pod wzgledem nawigacyjnym.
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Dynamic control of the receiving beam horizontal cross-section in the side scan sonar
PublikacjaW skonstruowanych przed kilkunastu laty a obecnie modernizowanych sonarach bocznych jako jeden z zabiegów modernizacyjnych wprowadzono dynamiczną regulację kąta rozwarcia odbiorczej charakterystyki kierunkowej w przekroju horyzontalnym. Regulacja taka zapewnia quasi-stałą rozdzielczość liniową sonaru (zamiast stałej rozdzielczości kątowej) przy odbiorze sygnałów echa ze wzrastających odległości od wykrywanych celów. W efekcie tego...
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THE SYNCHROSQUEEZING METHOD IN BEARING ESTIMATION OF STATIONARY SIGNALS FOR PASSIVE SONAR WITH TOWED ARRAY
PublikacjaIn this paper, a novel method of bearing estimation in a passive sonar system with a towed array is introduced. The classical approach of bearing estimation based on the spatial spectrum [1] is extended by using the synchrosqeezing method that is a part of the reassignment method introduced by Kodera et al. [2]. Using this method leads to a precise bearing estimation. The proposed method requires a relatively small amount of computation,...
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Continuous wave sonar with hyperbolic frequency modulation keyed by pseudo-random sequence
PublikacjaA CW FM type sounding signal is used in the classical solution of silent sonar. While the signal provides a relatively simple implementation of digital signal processing, and ensures good detection conditions, unfortunately, in the presence of the Doppler effect, distance measurement results tend to be wrong. This is due to the fact that the received signal’s instantaneous frequency value is dependent both on the distance to the...
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Mosaic Structure of p1658/97, a 125-Kilobase Plasmid Harboring an Active Amplicon with the Extended-Spectrum β-Lactamase Gene bla SHV-5
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Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
PublikacjaUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. A significant route of phase II drug metabolism is conjugation with glutathione (GSH), which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes. The aim of this work was to investigate the GSH-mediated metabolic pathway of a representative UA, C 2028. GSH supplemented incubations of C-2028 with rat, but not with human, liver...
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Photocatalytically Active TiO2/Ag2O Nanotube Arrays Interlaced with Silver Nanoparticles Obtained from the One-Step Anodic Oxidation of Ti–Ag Alloys
PublikacjaThe development of a photocatalyst with remarkable activity to degrade pollutants in aqueous and gas phase requires visible lightresponsive stable materials, easily organized in the form of a thin layer (to exclude the highly expensive separation step). In this work, we present a one-step strategy for synthesizing material in the form of a self-organized TiO2/Ag2O nanotube (NT) array interlaced with silver nanoparticles (as in a...
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Synthesis and Structure of Novel Copper(II) Complexes with N,O- or N,N-Donors as Radical Scavengers and a Functional Model of the Active Sites in Metalloenzymes
PublikacjaToevaluatetheantioxidantactivityofpotentialsyntheticenzymemimetics,wepreparednewfivecopper(II)complexesviaaself‐assemblymethodandnamedthem[Cu(2‐(HOCH2)py)3](ClO4)2(1),[Cu(2‐(HOCH2)py)2(H2O)2]SiF6(2),[Cu2(2‐(HOCH2CH2)py)2(2‐(OCH2CH2)py)2](ClO4)2(3),[Cu(pyBIm)3](BF4)2∙1.5H2O(4)and[Cu(py2C(OH)2)2](ClO4)2(5).ThesyntheticprotocolinvolvedN,O‐ orN,N‐donors:2‐(hydroxymethyl)pyridine(2‐(HOCH2)py),2‐(hydroxyethyl)pyridine(2‐(HOCH2CH2)py),2‐(2‐pyridyl)benzimidazole(pyBIm),di(2‐pyridyl)ke‐tone(py2CO).TheobtainedCu(II)complexeswerefullycharacterisedbyelementalanalysis,FTIR,EPR,UV‐Vis,single‐crystalX‐raydiffractionandHirshfeldsurfaceanalysis.Crystallographicandspectroscopicanalysesconfirmedchromophoresofbothmonomeric({CuN3O3}(1),{CuN2O4}(2),{CuN6}(4),{CuN4O2}(5))anddimericcomplex({CuN2O3}(3)).Mostoftheobtainedspeciespos‐sessedadistortedoctahedralenvironment,exceptdimer3,whichconsistedoftwocoppercentreswithsquarepyramidalgeometries.Thewater‐solublecompounds(1,3and5)wereselectedforbiologicaltesting.Theresultsofthestudyrevealedthatcomplex1insolutionsdisplayedbetterradicalscavengingactivitythancomplexes3,5andfreeligands.Therefore,complex1hasbeenselectedforfurtherstudiestotestitsactivityasanenzymemimetic.Thechosencompoundwastestedontheerythrocytelysateoftwogroupsofpatientsafterundergoingchemotherapyandchemoradiotherapy.Theeffectofthetestedcompound(1)onenzymeactivitylevels(TAS,SODandCAT)suggeststhattheselectedcomplexcanbetreatedasafunctionalmimeticoftheenzymes.
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Phytoplankton in the Gulf of Gdańsk– microscope photos archive
Dane BadawczeHarmful blooms of cyanobacteria an dinoflagellates are recorded every year in various areas of the Baltic Sea. The data set contains photos of potentially toxic phytoplankton species found in the Gulf of Gdańsk and Puck Bay. These photos show potentialy toxic cyanobacteria and dinoflagellates observed in the surface water samples collected between 2010-2020....
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Overproduction of CaMet15p native and His-tag versions.
Dane BadawczeEnzyme of fungal L-methionine biosynthetic pathway: O-acetylhomoserine sulfhydrylase (Met15p) could be exploited as molecular target for antifungal chemotherapy. The goal of the study was to obtain conditions optimal for protein production with the use of prokaryotic cells. The constructed expression plasmids, designed in three different versions: encoding...
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Phytoplankton in the Kashubian Lakes – microscopic photo archive
Dane BadawczePhytoplankton is a group of microscopic plant organisms passively floating in water. The organisms included in the phytoplankton of lakes include the following main taxonomic groups: cyanobacteria (Cyanobacteria), green algae (Chlorophyta), dinoflagellates (Dinophyta), diatoms (Bacillariophyceae), cryptophytes (Cryptophyta), chrysophytes (Chrysophyceae)...
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Overproduction of CaStr2p native and His-tag versions.
Dane BadawczeEnzyme of fungal L-methionine biosynthetic pathway: cystathionine-γ-synthase (CaStr2p) could be exploited as molecular target for antifungal chemotherapy. The goal of the study was to obtain conditions optimal for protein production with the use of prokaryotic cells. The constructed expression plasmids, designed in three different versions: encoding...
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Symulacja pracy przesuwnika fazowego w sieci elektroenergetycznej przy połączeniu transformatora szeregowego w gwiazdę
PublikacjaPoniższy artykuł prezentuje sposób regulacji mocy czynnej i biernej za pomocą przesuwnika fazowego, którego uzwojenie transformatora dodawczego (szeregowego) jest połączone w gwiazdę. W artykule pokazano regulację mocy czynnej i biernej na przykładzie wybranego systemu elektroenergetycznego. Omawiany przesuwnik fazowy reguluje jednocześnie przepływem mocy czynnej i biernej w danym systemie elektroenergetycznym.
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Extracellular matrix metalloproteinase inducer (EMMPRIN) expression correlates positively with active angiogenesis and negatively with basic fibroblast growth factor expression in epithelial ovarian cancer
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Immediate and late benefits of treating very elderly people with hypertension: results from active treatment extension to Hypertension in the Very Elderly randomised controlled trial
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N,N’-Bis(salicylidene)ethylenediamine (Salen) as an Active Compound for the Recovery of Ni(II), Cu(II), and Zn(II) Ions from Aqueous Solutions
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Porous carbon derived from rice husks as sustainable bioresources: insights into the role of micro-/mesoporous hierarchy in hosting active species for lithium–sulphur batteries
PublikacjaThe exploration of natural resources as sustainable precursors affords a family of green materials. Exploring highly abundant and available biowaste precursors remaining from food processing throughout a scalable and cost-effective material synthesis path is highly important especially for new materials discovery in emerging energy storage technologies such as lithium–sulphur (Li–S) batteries. Herein, we have produced a series...
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Moderately Reactive Molecules Forming Stable Ionic Compounds with Superhalogens
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Different Modes of Hydrogen Peroxide Action During Seed Germination
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Effect of pH on the Redox and Sorption Properties of Native and Phosphorylated Starches
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Modeling of Ozonation of Reactive Black 5 Through a Kinetic Approach
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Cadmium inhibitory action leads to changes in structure of ferredoxin:NADP+ oxidoreductase
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C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
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C-reactive protein as a diagnostic and prognostic factor of endometrial cancer
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Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates
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Mispronunciation Detection in Non-Native (L2) English with Uncertainty Modeling
PublikacjaA common approach to the automatic detection of mispronunciation in language learning is to recognize the phonemes produced by a student and compare it to the expected pronunciation of a native speaker. This approach makes two simplifying assumptions: a) phonemes can be recognized from speech with high accuracy, b) there is a single correct way for a sentence to be pronounced. These assumptions do not always hold, which can result...
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Prevalence Problem in the Set of Quadratic Stochastic Operators Acting on L1
PublikacjaThis paper is devoted to the study of the problem of prevalence in the class of quadratic stochastic operators acting on the L1 space for the uniform topology. We obtain that the set of norm quasi-mixing quadratic stochastic operators is a dense and open set in the topology induced by a very natural metric. This shows the typical long-term behaviour of iterates of quadratic stochastic operators.