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From DNA damage to G2 arrest: the many roles of topoisomerase II. W: Prog-ress in Cell Cycle Research. Ed. Meijer L., Jezequel A., Roberge M. London: Plenum Publ. Comp. Ltd**2003 vol. 5 chapt. 30 s. 295-300 Od uszkodzeń DNA do bloku w G2: wiele ról dla topoizomerazy II.
PublikacjaInhibitory DNA topoizomerazy II sa jednymi z najbardziej szeroko stosowanymi lekami przeciwnowotworowymi. Związki te indukuja pekniecia nici DNA i bloku progresji cyklu komorkowego w fazie G2. Jednak topoizomeraza II jest nie tylko celem molekularnym dla lekow przeciwnowtworowych ale enzym ten pelniwazna role w odpowiedzi komorkowej na dzialanie wielu lekow uszkadzajacych DNA. Topoizomeraza tworzy kompleksy molekularne z bialkami...
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Damage-Involved Structural Pounding in Bridges under Seismic Excitation
PublikacjaDuring severe earthquakes, pounding between adjacent superstructure segments of highway elevated bridges was often observed. It is usually caused by the seismic wave propagation effect and may lead to significant damage. The aim of the present paper is to show the results of the numerical analysis focused on damage-involved pounding between neighbouring decks of an elevated bridge under seismic excitation. The analysis was carried...
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Unveiling the electron-induced ionization cross sections and fragmentation mechanisms of 3,4-dihydro-2H-pyran
PublikacjaThe interactions of electrons with molecular systems under various conditions are essential to interdisciplinary research fields extending over the fundamental and applied sciences. In particular, investigating electron-induced ionization and dissociation of molecules may shed light on the radiation damage to living cells, the physicochemical processes in interstellar environments, and reaction mechanisms occurring in combustion...
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The particle method for simulation of self-organization phenomena
PublikacjaThe aim of the work was to design, implement, and use, in a number of experiments, an abstract software environment (an artificial world)suitable for modelling systems consisting of many moving and interactingobjects distributed in space. The environment, named DigiHive, is directed towards modeling of complex systems manifested by processes of self-organization, self-reproduction and self modifications. The environment is mainly...
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In silico epitope prediction of Borrelia burgdorferi sensu lato antigens for the detection of specific antibodies
PublikacjaDespite many years of research, serodiagnosis of Lyme disease still faces many obstacles. Difficulties arise mainly due to the low degree of amino acid sequence conservation of the most immunogenic antigens among B. burgdorferi s.l. genospecies, as well as differences in protein production depending on the environment in which the spirochete is located. Mapping B-cell epitopes located on antigens allows for a better understanding...
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Concentration levels of selected analytes in the gas phase of an e-cigarette aerosol
PublikacjaThe aerosols generated from e-cigarettes are composed of liquid and gas phases resulting from vapourized e-liquid. The apportioning of substances from e-liquid into the liquid and gas phases during e-cigarette use has not been extensively studied. Partitioning of e-liquid components between the gas and the liquid phase of the aerosol influences the substances inhaled and exhaled by the users, leading to second-hand exposure. It...
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A risk comparison framework for autonomous ships navigation
PublikacjaMaritime autonomous surface ships (MASS) may operate in three predefined operational modes (OM): manual, remote, or autonomous control. Determining the appropriate OM for MASS is important for operators and competent authorities that monitor and regulate maritime traffic in given areas. However, a science-based approach to this respect is currently unavailable. To assist the selection of the proper OM, this study presents a risk-based...
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Non linear identification of underwater vehicles. W: [CD-ROM] Conference Proceedings. The 29th Israel Conference on Mechanical Engineering. May 12-13, 2003 Haifa, Israel. Haifa: Technion - Israel Inst. Technol.**2003[B8] s. 1-8, 5 rys. bibliogr. 7 poz. Nieliniowa identyfikacja pojazdów podwodnych.
PublikacjaArtykuł dotyczy identyfikacji nieliniowych modeli pojazdów podwodnych o wie-lu zmiennych. Zaproponowana metoda działa w obszarze czasu rzeczywistego imoże być stosowana do nieliniowych modeli, które są liniowe w części doty-czącej nieznanego wektora parametrów. W celu poradzenia sobie z parametramizmieniającymi się w czasie, zastosowano rekursyjną wersję algorytmu identy-fikacji. Po krótkim opisie matematycznych podstaw...
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Legal and Economic Conditions of the Creating and Activity of Entrepreneursin Poland. VATT Governement Inst. Econ. Res. C**2002 [nr] 290 s. 153- 162 bibliogr. 10 poz. Discussion papers. Workshopon Studies for Nordther. Kalastajatorrpa,30-31 May 2002.Prawne i ekonomiczne uwarunkowania działalności przedsiębiorców w Polsce.
PublikacjaW artykule przedstawiono warunki prawne, które muszą być spełnione przyuruchamianiu działalności gospodarczej w Polsce. Wskazano również co sprzyjai co hamuje rozwój działalności przedsiębiorców w naszym kraju.
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Distributed wireless sensor for measuring humidity and temperature
PublikacjaHumidity and temperature monitoring is often required in industrial halls and laboratories and can be crucial, because many properties of electrical devices deteriorates under influence of these parameters. There are several useful commercial methods for measuring humidity and temperature, such as commercial hygrometers and humidity recorders. However, they do not allow data acquisition simultaneously from multiple sensors. This...
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System setup and software for cyclic, staircase and square wave voltammetry measurements
PublikacjaHardware dedicated for electrochemical measurement sometimes does not allow performing certain voltammetry experiments. Staircase and square wave voltammetry, techniques which have many advantages comparing with standard voltammetric techniques, are rarely implemented in software controlling electrochemical measuring equipment. These methods, however, can be relatively easy realized with some addition...
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Lean Startup as a New Way of Managing Technology Ventures Illustrated by the Example of Wlcome App
PublikacjaThe dot-com bubble in the 1990s made the technology industry aware that even excellent ideas backed by amazing teams are not sufficient to ensure a startup’s success. The biggest risk of startups is that they have to operate within many uncertainties, their market and customers are unknown, and their business model is not yet validated. Therefore, successful execution of such a venture requires a rigorous process that would validate...
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EXPERIENCE-ORIENTED SMART EMBEDDED SYSTEM
PublikacjaThe Experience-Oriented Smart Embedded System (EOSES) is proposed as a new technological platform providing a common knowledge management approach that allows mass embedded systems for experiential knowledge capturing, storage, involving, and sharing. Knowledge in the EOSES is represented as SOEKS, and organized as Decisional DNA. The platform is mainly based on conceptual principles from Embedded Systems and Knowledge Management....
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Phytotoxic Activity of Metabolites Isolated from Rutstroemia sp.n., the Causal Agent of Bleach Blonde Syndrome on Cheatgrass (Bromus tectorum)
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Identification of X-DING-CD4, a new member of human DING protein family that is secreted by HIV-1 resistant CD4+ T cells and has anti-viral activity
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The need for linear revitalization. Gdynia case
PublikacjaThe aim of the article is to discuss the need of defining and implementation of the linear revitalization - the new approach related to the revitalization processes. The results of the preliminary investigations indicate that this kind of revitalization seems to be an important tool supporting city management and planning, especially in cases of cities fragmentation - causing lack of physical, social, economic and ecological cohesion....
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Jubileusz 75-lecia prof. zw. dr hab. inż. Karola Franciszka Macheja
PublikacjaPrzedstawiono drogę zawodową Profesora Karola Macheja. Scharakteryzowano kierunki badań rozwijane przez Profesora. Wskazano osiągnięcia z zakresu badań przenikania masy w wypełnionych aparatach kolumnowych, osiągnięcia w zakresie zastosowań rachunku krakowianowego do zagadnień inżynierii chemicznej, osiągnięcia w zakresie badań równoczesnej wymiany ciepła i masy, osiągniecia z zakresu badań nad krystalizacją masową.
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Mechanizmy zniszczenia kompozytów epoksydowych wzmocnionych włóknami węglowymi i aramidowymi.
PublikacjaW celu obniżenia ryzyka gwałtownego pękania oraz masy konstrukcji, laminaty wzmocnione włóknami węglowymi mogą być zastępowane przez hybrydowe aramidowo-węglowe. Problemem jest zachowanie pod obciażeniem przy okresowym zanurzeniu w wodzie. Przedstawiono mapy naprężeń oraz odkształceń niszczących w laminatch epoksydowych wzmocnionych tkaninami węglową i aramidową opracowane w oparciu o badania wytrzymałości na zginanie próbek w...
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Modelling of dryout process in an annular flow
PublikacjaW pracy pokazano teoretyczny model kryzysu wrzenia przy wysokich stopniach suchości, który jest modyfikacją modelu proponowanego wcześniej przez Sedlera i Mikielewicza. Model wysychania filmu cieczowego w przepływie pierścieniowym składa się z różniczkowych równań bilansu masy zapisanych dla filmu na ściance i kropel w rdzeniu przepływu. Rozwiązanie układu równań wymaga znajomości gęstości strumienia masy kropel wytrącających się...
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Modelling of dryout process in annular flow
PublikacjaW pracy pokazano teoretyczny model kryzysu wrzenia przy wysokich stopniach suchości, który jest modyfikacją modelu proponowanego wcześniej przez Sedlera i Mikielewicza. Model wysychania filmu cieczowego w przepływie pierścieniowym składa się z różniczkowych równań bilansu masy zapisanych dla filmu na ściance i kropel w rdzeniu przepływu. Rozwiązanie układu równań wymaga znajomości gęstości strumienia masy kropel wytrącających się...
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Badania korelacji retencji z właściwościami fizykochemicznymi wybranych grup organicznych związków siarki w podziałowej chromatografii gazowej
PublikacjaZastosowanie podziałowej chromatografii gazowej z niepolarną ciekłą fazą stacjonarną pozwala na elucję analitów zgodnie z ich temperaturą wrzenia. Na tej podstawie powstała metoda symulowanej destylacji, w której wykorzystuje się chromatografie gazową i wzorce temperatury wrzenia w postaci n-parafin do wyznaczania krzywych destylacji produktów naftowych. Zależności korelacyjne wynikające z możliwości przewidzenia oddziaływań, a...
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Honey as an indicator of heavy metals in the environment
PublikacjaHoney bees collect nectar, pollen and honeydew to produce bee products. One of them is honey, which due to chemical composition and properties is considered by human as a valuable food product. When honey bees collect substrates to produce honey they can bring contaminants to the hive. The presence of xenobiotics in bee products may lower their quality and devalue their properties, and also endanger human health. Many scientists...
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Polymer biodegradable coatings as active substance release systems for urological applications
PublikacjaCatheter-associated urinary tract infections are the result of catheterization of the bladder. The risk of infection is directly proportional to the length of the bladder catheterization. Bacteria cells have the ability to adhere and create the biofilm on the surface of catheter materials. Bacteria’s biofilm is an extremely beneficial environment of existence for microorganisms. Microorganisms that are an integral part of the biofilm...
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Comparison of state feedback and PID control of pressurizer water level in nuclear power plant
PublikacjaThe pressurizer water level control system in nuclear power plant with pressurized water reactor (PWR) is responsible for coolant mass balance. The main control goal is to stabilize the water level at a reference value and to suppress the effect of time-varying disturbances (e.g. coolant leakage in primary circuit pipeline system). In the process of PWR power plant operation incorrect water level may disturb pressure control or...
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INFORMATION ABOUT DYNAMICS OF THE SEA SURFACE AS A MEANS TO IMPROVE SAFETY OF THE UNMANNED VESSEL AT SEA
PublikacjaOne of the fundamental states of the sea surface is its heave. Despite of years of the intense scientific inquiry, no clear understanding of the influence of this aspect on the dynamics of the sea environment has emerged. The separation of two nearby fluid elements which one may observed for example as a free floating of small objects on the sea surface (rescuers on the rough sea or small research vessels) is caused by the interaction...
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Nadzorowanie drgań układu nośnego robota przemysłowego IRB-6 za pomocą ste-rowania modalnego przy energetycznym wskaźniku jakości. W: Zagadnienia ana- lizy modalnej konstrukcji mechanicznych. Praca zbiorowa pod red. T. Uhla. Kraraków: Kated. Robotyki i Dynam. Masz. AGH**2003 s. 115-122, 2 rys. 1 tab. bibliogr. 4 poz.
PublikacjaW pracy rozważa się drgania modelowanego dyskretnie niestacjonarnego układunośnego manipulatora IRB6 metodą sztywnych elementów skończonych. Do nadzo-rowania drgań wykorzystano algorytm sterowania optymalnego przy energetycz-nym wskaźniku jakości w dziedzinie współrzędnych modalnych. Uwzględnia on zmianę w czasie, względem trajektorii ruchu zadanego, energii potencjalnej, kinetycznej oraz energii sygnału sterującego.
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Dynamics analysis of footbridge mode shapes the s8 expressway on the basis of the results of in situ tests
PublikacjaNon-destructive diagnostics for structure may use dynamic measurements realized during vibrations of a facility induced by dynamic environmental impact, enforced by the use of inductors or impulse impact. Dynamic tests and the analysis were undertaken for a footbridge situated over the expressway S8. The studies in situ allowed for dynamic characteristics to be determined: frequency, shape modes and damping for respective frequency...
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Facial data registration facility for biometric protection of electronic documents
PublikacjaIn modern world, information is crucial, and its leakage may lead to serious losses. Documents as the main medium of information must be therefore highly protected. Nowadays, the most common way of protecting data is using passwords, however it seems inconvenient to type complex passwords, when it is needed many times a day. For that reason a significant research has been conducted on biometric authentication...
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Traffic Remapping Attacks in Ad Hoc Networks
PublikacjaAd hoc networks rely on the mutual cooperation of stations. As such, they are susceptible to selfish attacks that abuse network mechanisms. Class-based QoS provisioning mechanisms, such as the EDCA function of IEEE 802.11, are particularly prone to traffic remapping attacks, which may bring an attacker better QoS without exposing it to easy detection. Such attacks have been studied in wireless LANs, whereas their impact in multihop...
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Ion Chromatography in Environmental Analysis of Selected Organic Acids
PublikacjaLow molecular mass carboxylic acids (LCAs) occur in many environmental compartments dueto natural processes and human activity. When volatile and nonvolatile acids are to be monitored then liquidchromatography, including ion chromatography seems a method of choice. At high pH the acids are inionized form and can be separated as carboxylats by means of anion exchange chromatography. LCAs canalso be separated at low pH by ion exclusion...
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Modal analysis of a steel grandstand
PublikacjaAmong the issues related to the idea of sustainable society is the safety of civil engineering structures devoted to satisfy different needs of people. One of the types of structures devoted to satisfy recreational needs are grandstands, which are used during sport events or music concerts. It is obligatory to consider interaction between structure and crowd load especially when the crowd movement involves rhythmic jumping, dancing,...
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Algorithms for Ship Movement Prediction for Location Data Compression
PublikacjaDue to safety reasons, the movement of ships on the sea, especially near the coast should be tracked, recorded and stored. However, the amount of vessels which trajectories should be tracked by authorized institutions, often in real time, is usually huge. What is more, many sources of vessels position data (radars, AIS) produces thousands of records describing route of each tracked object, but lots of that records are correlated...
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Seasonal variability and morphological structure of bacteria in the Admiralty Bay (King George Island, Antarctic).
PublikacjaIntroduction: The aim of investigations was to state whether melting glaciers cause mass mortality of the sea stenohalyne organisms, what in consequence can lead to an increase of accumulation and growth of psychrophilic bacteria. It may be also that fresh melting water is unfavourable to the sea bacteria and front glacier's regions are not the areas of their intensive development. Methods: Field investigations were done in Admiralty...
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Waste materials assessment for phosphorus adsorption toward sustainable application in circular economy
PublikacjaPhosphorus is the main determinant of nutrient enrichment in the water bodies. Many resources including nutrients may be shortly exhausted, assuming current consumption. This scenario leads to growing interest in resources recovery and/or reuse, which together with sustainable energy consumption and waste reduction are the main courses of the circular economy. Usage of coagulants in wastewater treatment plants (WWTP) does not allow...
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Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug detoxification and bioactivation.
PublikacjaThe effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione, which can be non-enzymatic and/or catalyzed by glutathione-dependent enzymes. Glutathione usually combines with anticancer drugs and/or their metabolites to form more polar...
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Możliwości odzysku fosforu z odcieków, osadów ściekowych i popiołów po termicznym przekształcaniu osadów ściekowych
PublikacjaW ostatnich latach zaobserwowano rosnącą świadomość o ograniczonych zasobach fosforu. Szacuje się, że mogą one ulec wyczerpaniu w ciągu 100 lat, przy obecnym zaawansowaniu technologii. Ponad 80% wydobywanego złoża wykorzystywane jest do produkcji nawozów sztucznych oraz w przemyśle chemicznym. Taka perspektywa zwiększa zainteresowanie recyklingiem fosforu, który może być odzyskiwany ze ścieków w fazie płynnej, z odwodnionych osadów...
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Using Statistical Methods to Estimate The Worst Case Response Time of Network Software Running on Indeterministic Hardware Platforms
PublikacjaIn this paper we investigate whether the statistical Worst Case Execution Time (WCET) estimation methods devised for embedded platforms can be successfully applied to find the Worst Case Response Time (WCRT) of a network application running on a complex hardware platform such as a contemporary commercial off-the-shelf (COTS) system. Establishing easy-to-use timing validation techniques is crucial for real-time applications and...
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Thermo-Chemical Decomposition Study of Polyurethane Elastomer Through Glycerolysis Route with Using Crude and Refined Glycerine as a Transesterification Agent
PublikacjaDue to the increasing amount of polyurethane waste, chemical recycling of these materials is a topic of growing interest for many researchers. The primary pur- pose of polyurethane feedstock recycling is to recover the starting polyol. In this study glycerolysis using glycerine from two sources and two purity grades is proposed as a method of chemical recycling. The main effort of this paper focuses on the employment of commercial...
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The impact of sediment, fresh and marine water on the concentration of chemical elements in water of the ice-covered lagoon
PublikacjaThe common use of chemical elements by man has been contributing to their extraction for centuries. As a consequence, they have been directly or indirectly introduced into the biogeochemical cycle. In the framework of many conventions, mining and processing of elements are currently subject to many restrictions. However, their large load that has already been deposited in the soil and bottom sediments can be remobilised and...
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Ionic liquids-based microextraction techniques
PublikacjaIn recent years, the development of highly efficient analytical techniques is of great importance, however, the direct analysis of complex sample matrix is still impossible in many cases. Therefore, the step of sample preparation is commonly involved in an analytical procedure. Over the years, it has been realized that the major source of inaccuracy and imprecision on general analysis results from the operations associated to sample...
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Numerical model for thin liquid film with evaporation and condensation on solid surfaces in systems with conjugated heat transfer
PublikacjaCondensation and evaporation processes from wetted surfaces are of utmost importance in many technological or industrial applications. In many devices such as home-appliances and air conditioning systems just to name a few, condensation and evaporation processes greatly impact their performance and energy efficiency; The physics of these processes is quite complex, involving conjugate heat transfer among solid–liquid film-gaseous...
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Experimental study of flow pattern and heat transfer during steam drying of wood
PublikacjaBadania wysokotemperaturowego suszenia drewna zostały zainspirowane koniecznością instensyfikacji wymiany ciepła i masy na potrzeby przemysłu drzewnego, a w szczególności meblarskiego, w zakresie doskonalenia metod suszenia drewna, modelowania intensyfikacji wymiany ciepła i masy w elementach suszonych, opracowania ekologicznych i energooszczędnych systemów suszarniczych, ochrony środowiska związanej z racjonalnym zużyciem energii,...
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Symulacje modelowe migracji zanieczyszczeń w okolicy składowiska odpadów w Gdańsku-Szdółkach
PublikacjaPrzeprowadzone badania na wielowarstwowym modelu hydrodynamicznym i symulacje transportu masy w strumieniu zanieczyszczeń umożliwiły określenie kierunku i szybkości migracji odcieków ze składowiska w Szadółkach. Na podstawie rozkładu stężeń zanieczyszczeń oraz bilandu masy jonó chlorkowych stwierdzono, że zanieczyszczenie migruje do pierwszej i drugiej czwartorzędowej warstwy wodonośnej. Nie stwierdzono zanieczyszczenia trzeciego...
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Modelowanie i symulacja ruchu pojazdu zabytkowego podczas hamowania
PublikacjaOpracowano model samochodu zabytkowego z wykorzystaniem metody masa-sprężyna, służącego do symulacji procesu hamowania pojazdu zabytkowego z możliwością pomiaru drogi hamowania. Konfiguracja sieci połączeń między punktami mas elementów zawieszenia oraz opony okazuje się mieć bardzo duży wpływ na zachowanie symulowanego samochodu podczas hamowania. Poprawność symulacji sprawdzono porównując wyniki uzyskane z symulacji oraz z pomiarów...
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Possibilities of radioisotope measuring in control of an unstable solid particles hydrotransport
PublikacjaThe paper presents γ-radiation proposal to control a multiphase flow, independently from circumstances. So this method may be applied even in compound industrial or environmental processes. Moreover in many cases, it is the only method for applications for dense mixture containing coarse angular grains. The constructed equipment allows continuous measurement of density as well as solid phase for both concentration and average velocity....
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Effect of the let-through energy of overcurrent protective devices on the temperature of conductors during short-circuits
PublikacjaThe scope of the verification of low-voltage systems covers the earth fault loop impedance measurement. This measurement is usually performed with the use of low-value current meters, which force a current many times lower than the one occurring during a real short-circuit. Therefore, the international standard recommends consideration of the increase of resistance of conductors with the increase of temperature, which may occur...
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Application of the Boundary Element Method for the Simulation of Two-dimensional Viscous Incompressible Flow
PublikacjaThe paper presents the application of an indirect variant of the boundary element method (BEM) to solve the two-dimensional steady flow of a Stokes liquid. In the BEM, a system of differential equations is transformed into integral equations. Thi smakes it possible to limit discretization to the border of the solution. Numerical discretization of the computational domain was performed with linear boundary elements, for which a...
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Phytotoxic Metabolites from Three Neofusicoccum Species Causal Agents of Botryosphaeria Dieback in Australia, Luteopyroxin, Neoanthraquinone, and Luteoxepinone, a Disubstituted Furo-α-pyrone, a Hexasubstituted Anthraquinone, and a Trisubstituted Oxepi-2-one from Neofusicoccum luteum
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Performance of a single layer fuel cell based on a mixed proton-electron conducting composite
PublikacjaMany of the challenges in solid oxide fuel cell technology stem from chemical and mechanical incompatibilities between the anode, cathode and electrolyte materials. Numerous attempts have been made to identify compatible materials. Here, these challenges are circumvented by the introduction of a working single layer fuel cell, fabricated from a composite of proton conducting BaCe0.6Zr0.2Y0.2O3-δ and a mixture of semiconducting...
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Pesticide Analysis of Bee and Bee Product Samples
PublikacjaBee products possess therapeutic properties and are the source of many essential trace elements,which is why they are regarded as valuable food products. Honey bees may bring to thehive numerous contaminants deposited on the plants they visit, including pesticide withoutxenobiotics. The large-scale application of pesticides in agriculture and horticulture can lead tomass mortality among bees, and the chemicals find their way into...