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Search results for: fundament%20palowy

  • 8-Oxoguanine incision activity is impaired in lung tissues of NSCLC patients with the polymorphism of OGG1 and XRCC1 genes

    Publication
    • J. Janik
    • M. Swoboda
    • B. Janowska
    • J. Cieśla
    • D. Gackowski
    • J. Kowalewski
    • R. Olinski
    • B. Tudek
    • E. Speina

    - MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS - Year 2011

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  • DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine

    Publication
    • M. Cooke
    • M. Evans
    • R. Dove
    • R. Rozalski
    • D. Gackowski
    • A. Siomek
    • J. Lunec
    • R. Olinski

    - MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS - Year 2005

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  • Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples

    Publication

    - Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Year 2005

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  • Central carbon metabolism influences fidelity of DNA replication in Escherichia coli

    Publication
    • M. Maciąg
    • D. Nowicki
    • A. Szalewska-Pałasz
    • G. Węgrzyn

    - Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis - Year 2012

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  • Conserved motifs of MutL proteins

    tThe MutL protein is best known for its function in DNA mismatch repair (MMR). However, there isevidence to suggest that MutL is not only the linker connecting the functions of MutS and MutH in MMR,but that it also participates in other repair systems, such as Very Short Patch (VSP), Base Excision (BER)and Nucleotide Excision Repair (NER). This study set out to identify the most highly conserved aminoacid sequence motifs in MutL...

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  • O istocie dogmatyzmu z punktu widzenia filozofii krytycznej

    Publication

    - Year 2010

    "O istocie dogmatyzmu z punktu widzenia filozofii krytycznej" przedstawia metodyczne założenia filozoficznej opozycji "dogmatyzm-krytycyzm", stanowiącej jeden z głównych fundamentów doktryny neokantowskiej szkoły marburskiej. Autor w oparciu o prace Kanta, Cohena, Natorpa i Cassirera prezentuje warunki możliwości oraz mechanizmy powstawania budowanych substancjalnie dogmatyzmów (takich jak choćby system filozoficzny Ch. Wolffa),...

  • Uwarunkowania techniczne prac remontowych modernistycznych kamienic gdyńskich

    Publication

    W artykule przedstawiono przykłady rozwiązań konstrukcyjno-materiałowych przedwojennych wielorodzinnych budynków mieszkalnych realizowanych w Gdyni na terenie dzielnicy Działki Leśne które obecnie, w czasie prowadzenia prac remontowo-modernizacyjnych powodują powstawanie znacznych utrudnień wydłużając czas robót budowlanych oraz generując dodatkowe koszty. Na przykładzie fundamentów, stropów oraz murów...

  • Investigation of Transmit and Receive Characteristics of Laboratory Model for the Parametric Echosounder

    Publication

    - ACTA PHYSICA POLONICA A - Year 2013

    Investigation and operation of devices based on nonlinear interaction of high-intensity waves have been carried out for several decades. However, it is still a new tool to study the properties of the water environment and especially the upper layers of the seabed. This paper describes the results of tests of the new device that is intended to be applied for sounding underwater areas. The device has been designed and built in collaboration with...

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  • Redundancja jako sposób zwiększenia niezawodności siłowni okrętowych

    Publication

    Jednym z istotnych sposobów zapewnienia wysokiego poziomu niezawodności siłowni okrętowych jest zaprojektowanie redundancji jego elementów strukturalnych, np.: nadmiarowości strukturalnej systemów generowania energii, układów napędowych itp. W niniejszym artykule omówiono zagadnienia związane z nadmiarem, jako sposobem zwiększenia niezawodności systemów generowania energii i napędu statku. W szczególności zaś zostały zaprezentowane...

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  • Kładka łukowa przez Wartę we Wronkach : Projekt i realizacja.

    Publication

    W referacie przedstawiono historię projektowania i realizacji nietypowej kładki z przęsłem łukowym o rozpiętości 90 m. Pierwotny zamysł architektoniczny został zrealizowany dzięki opracowaniu nowego projektu konstrukcyjnego. W fazie projektowania skoncentrowano się na ukształtowaniu konstrukcji tak, aby zoptymalizować zużycie stali i nakłady na fundamenty. Istotnym elementem projektu było dobranie charakterystyk dynamicznych tak,...

  • Human voice modification using instantaneous complex frequency

    Publication
    • M. Kaniewska

    - Year 2010

    The paper presents the possibilities of changing human voice by modifying instantaneous complex frequency (ICF) of the speech signal. The proposed method provides a flexible way of altering voice without the necessity of finding fundamental frequency and formants' positions or detecting voiced and unvoiced fragments of speech. The algorithm is simple and fast. Apart from ICF it uses signal factorization into two factors: one fully...

  • New approach to railway noise modeling employing Genetic Algorithms

    Publication

    Main goal of this paper was to describe an innovative method of noise prediction based on Genetic Algorithms. First part of the paper addresses the problem of growing noise, mainly in the context of a unified method for measuring noise. Further, Genetic Algorithms are described with regards to their fundamental features. Further a description is provided as to how Genetic Algorithms were used in the area of noise modeling. Next...

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  • Dynamics Conscious Approach to Tribometer Design and Tribo-testing

    In the paper findings are discussed on the issue of dynamic characteristics of a tribometer as a factor influencing the result of the tribological experiment. An advanced approach to tribo-testing is attempted with integrated dynamic analysis of the tribometer and the sliding pair. The fundamental idea is explored of the tribometer being regarded as any machine in which friction is inflicted with all the resulting consequences...

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  • Intelligent turbogenerator controller based on artifical neural network

    The paper presents a desing of an intelligent controller based on neural network (ICNN). The ICNN ensures at the same time two fundamental functions : the maintaining of generator voltage at the desired value and the damping of the electromechanical oscillations. Its performance is evaluted on a single machine infinite bus power system through computer simulations. The dynamic and transient operation of the proposed controller...

  • Project Team Management Supported by an Agent-Based Model

    Publication

    This work is a continuation of a series of works about research into the use of multi-agent systems to support IT project management. Previous studies have shown the possibility of using a multi-agent in order to optimize management decisions concerning the selection of methods for project implementation. It was noted that the project manager's decisions are influenced by three fundamental parameters: the entropy of the project,...

  • Towards neural knowledge DNA

    Publication

    - JOURNAL OF INTELLIGENT & FUZZY SYSTEMS - Year 2017

    In this paper, we propose the Neural Knowledge DNA, a framework that tailors the ideas underlying the success of neural networks to the scope of knowledge representation. Knowledge representation is a fundamental field that dedicates to representing information about the world in a form that computer systems can utilize to solve complex tasks. The proposed Neural Knowledge DNA is designed to support discovering, storing, reusing,...

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  • Concept of managing quality in baking industry, in vector representation

    The author introduced an innovative metrisable method of describing a manufacturing process. The idea of vector structure of a manufacturing process allows to formulate quantitative relations between the activity of input streams, elements of product quality, and measurable effects of losses. The structure was basis for the formulation of the concept of the process of managing product quality in the baking industry in a vector...

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  • Single and Series of Multi-valued Decision Diagrams in Representation of Structure Function

    Publication

    - Year 2022

    Structure function, which defines dependency of performance of the system on performance of its components, is a key part of system description in reliability analysis. In this paper, we compare two approaches for representation of the structure function. The first one is based on use of a single Multi-valued Decision Diagram (MDD) and the second on use of a series of MDDs. The obtained results indicate that the series of MDDs...

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  • Modelling of MV and HV Cable Lines

    Overhead and cable lines are fundamental elements of power systems. Participation of cable lines is smaller and their percentage decreases as voltage is increased. HV cable lines are often built with the use of cables which are composed of coaxial metallic sheaths. Such cables are also often used in MV networks. The sheath may operate in different confgurations. In the case of Polish MV network the sheaths are earthed at both ends....

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  • Profesjonalizm w pracy zawodowej

    Publication

    - Year 2017

    Artykuł jest analizą cechy profesjonalizmu w pracy zawodowej, ze szczególnym uwzględnieniem zawodów technicznych. Autorka podnosi problem nierozerwalnego związku między działaniem respektującym zasady etyczne i sprawnością zawodową, jako fundamentu wyborów określanych mianem profesjonalnych . Zaproponowana przez autorkę triada - odpowiedzialność, wiedza i doświadczenie - to nie tylko warunek i gwarancja profesjonalizmu, ale...

  • Error analysis of calculating average d-q current components using Regular Sampling and Park transformation in FOC drives

    Publication

    - Year 2014

    In electric drives using voltage source inverters, motor currents contain ripple component resulting from pulse-width modulated (PWM) voltage. The frequency range of the ripples is much higher than the bandwidth of current control. Therefore the control is performed on the basis of a fundamental current component, i.e. average value with the averaging time being the PWM period. In majority of cases the average current is measured...

  • Internet photogrammetry for inspection of seaports

    Publication

    - Polish Maritime Research - Year 2017

    This paper intends to point out the possibility of using Internet photogrammetry to construct 3D models from the images obtained by means of UAVs (Unmanned Aerial Vehicles). The solutions may be useful for the inspection of ports as to the content of cargo, transport safety or the assessment of the technical infrastructure of port and quays. The solution can be a complement to measurements made by using laser scanning and traditional...

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  • Suppression of Supply Current Harmonics of 18-Pulse Diode Rectifier by Series Active Power Filter with LC Coupling

    Publication

    - ENERGIES - Year 2020

    The reported research aims at improving the quality of three-phase rectifier supply currents. An effective method consists of adding properly formed booster voltages to the fundamental supply voltages using a series active filter. In the proposed solution, the booster voltages are generated by three single-phase systems consisting of inverters, LC filters, and single-phase transformers. The application of LC couplings ensures low...

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  • Catalytic Mechanism of Non-Target DNA Cleavage in CRISPR-Cas9 Revealed by Ab Initio Molecular Dynamics

    Publication

    - ACS Catalysis - Year 2020

    CRISPR-Cas9 is a cutting-edge genome editing technology, which uses the endonuclease Cas9 to introduce mutations at desired sites of the genome. This revolutionary tool is promising to treat a myriad of human genetic diseases. Nevertheless, the molecular basis of DNA cleavage, which is a fundamental step for genome editing, has not been established. Here, quantum–classical molecular dynamics (MD) and free energy methods are used...

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  • An Instantaneous Engine Speed Estimation Method Using Multiple Matching Synchrosqueezing Transform

    Publication
    • Y. Liu
    • H. Wen
    • Z. Ding
    • L. Xu
    • H. Chen
    • J. Smulko

    - Journal of Sensors - Year 2021

    Instantaneous rotational speed measurement of the engine is crucial in routine inspection and maintenance of an automobile engine. Since the contact measurement of rotational speed is not always available, the vibration measurement has been used for noncontact rotational speed estimation methods. Unfortunately, the accuracy of the noncontact estimation methods by analyzing engine vibration frequency is not satisfactory due to the...

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  • Modelling of saturated, subcooled and post-dryout flow boiling with the energy dissipation based semi-empirical model

    Publication

    - Year 2019

    A comprehensive semi-empirical model for saturated, subcooled and post dryout heat transfer is presented based on considerations of energy dissipation in the flow. The fundamental hypothesis in the model is the fact that heat transfer during flow boiling can be treated as a sum of two contributions constituting the total energy dissipation in the flow, namely the energy dissipation due to the shearing flow without the bubbles and...

  • Metodyka i wyniki geotechnicznych badań modelowych z wykorzystaniem techniki PIV

    Przedstawiono metodykę przygotowywania i wykonywania własnych badań modelowych w gruncie naturalnym i w ośrodku analogowym Taylor-Schneebeli, bez zbrojenia i ze zbrojeniem. Zamieszczono opis stanowisk badawczych używanych gruntów i zbrojenia oraz pomiarów przemieszczeń techniką PIV. Przedstawiono obszerne wyniki ilościowe i jakościowe badań modelowych stateczności fundamentów bezpośrednich posadowionych na zboczu z gruntu naturalnego...

  • SELECTION OF DIAGNOSTIC FUNCTIONS IN A WHEELED TRACTOR

    Publication

    - Diagnostyka - Year 2013

    In a classical approach to damage diagnosis, the technical condition of an analyzed machine is identified based on the measured symptoms, such as performance, thermal state or vibration parameters. In wheeled tractor the fundamental importance has monitoring and diagnostics during exploitation concerning technical inspection and fault element localizations. The main functions of a diagnostic system are: monitoring tractor components...

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  • Approaching Secure Industrial Control Systems

    Publication

    This study presents a systematic approach to secure industrial control systems based on establishing a business case followed by the development of a security programme. To support these two fundamental activities the authors propose a new method for security cost estimation and a security assessment scheme. In this study they explain the cost evaluation technique and illustrate with a case study concerning the assessment of the...

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  • Approach to evaluation of time to the critical degradation of ship pipelines

    Publication

    In the article an approach to the problem of estimating time to the critical degradation of ship pipelines is considered. Such an assessment would consist of six stages. The fundamental idea is to include to the estimation of time to failure of pipelines such elements like: materials that the pipelines are made, destructive physical phenomena taking place in them and applied means of protection. The result of that evaluation should...

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  • Entanglement and Nonlocality are Inequivalent for Any Number of Parties

    Publication

    - PHYSICAL REVIEW LETTERS - Year 2015

    Understanding the relation between nonlocality and entanglement is one of the fundamental problems in quantum physics. In the bipartite case, it is known that these two phenomena are inequivalent, as there exist entangled states of two parties that do not violate any Bell inequality. However, except for a single example of an entangled three-qubit state that has a local model, almost nothing is known about such a relation in multipartite...

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  • Problemy bezpieczeństwa podatkowego przedsiębiorców

    Publication

    - Year 2006

    Podstawowym fundamentem, na jakim można budować stategię finansową, a w szczególności stategię podatkową jest poczucie bezpieczeństwa podatkowego. Obszar bezpieczeństwa jest bardzo rozległy i stanowi pewien system konsekwentnych badań, realizowanych zarówno przez ustawodawcę, jak i przez aparat skarbowy. W Polsce przedsiębiorcy wskazują na zbyt niskie poczucie bezpieczeństwa podatkowego uzasadniając to wieloma przyczynami jak np....

  • Ernst Cassirer’s Idea of the Critique of Knowledge

    Publication

    The article analyses systematically and historically the specific idea of transcenden-talism developed in the Marburg School of Neo-Kantianism. The unique line of the Marburg’s School interpretation of Kant’s critical philosophy consists in contrasting critical (relational) and dogmatic (substantial) understandings of basic philosophical concepts. This line is characteristic of the Marburg School...

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  • Rzeczywista nośność pali w gruntach ilastych z zastosowaniem zaleceń PN-EN 1997-1:2004

    Publication

    - Year 2011

    Obecnie co raz więcej obiektów posadawianych jest w gruntach słabych bądź o specyficznych parametrach, do takich gruntów zalicza się iły. Jedną z podstawowych możliwości posadowienia w gruntach ilastych jest posadowienie na palach. Projektowanie fundamentów na palach dla takich warunków wymaga specjalnego i indywidualnego podejścia. W pracy przedstawiono przegląd metod i uwag w oparciu o PN-EN 1997-1:2004, którymi należy kierować...

  • 9 - Solid oxide fuel and electrolysis cells

    Publication
    • C. Lenser
    • D. Udomsilp
    • N. Menzler
    • P. Holtappels
    • T. Fujisaki
    • L. Kwati
    • H. Matsumoto
    • A. Sabato
    • F. Smeacetto
    • A. Chrysanthou
    • S. Molin

    - Year 2019

    In this chapter, the fundamental reactions, the geometrical designs, the material requirements, and the status of SOFCs and SOECs are presented. In the following seven chapters, the most important components of an SOC are described and the chapter ends with a summary and outlook. The described components are: (i) oxygen-ion conductors (electrolyte), (ii) anode materials for SOFCs (cathode in SOEC mode), (iii) cathode materials...

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  • Evaluation of Sound Enhancement in Mobile Device Using Virtual Bass Synthesiss Algorithm

    Publication

    An experiment conducted to validate possibility of use virtual bass synthesis (VBS) algorithm in a portable computer is presented. The subjective listening tests based on the procedure of pairwise comparison between VBS, based on the so-called missing fundamental phenomenon, and standard bass boost technique are employed. The evaluation was carried out in two types of conditions: in a professional listening room and employing an...

  • Praktyka wykonywania pomiarów instalacji fotowoltaicznych prowadząca do określenia rzeczywistego stanu technicznego

    Praca przedstawia zasady wykonywania pomiarów instalacji fotowoltaicznych wg normy PN-EN 62446-1. Proponowany w normie zakres podstawowy pozwala tylko na ocenę bezpieczeństwa pracy instalacji. Dopiero zakres dodatkowy umożliwia uzyskanie informacji o referencyjnych mocach zainstalowanej elektrowni, jej sprawności, a nawet jednorodności poszczególnych ogniw fotowoltaicznych. Załączone przykłady pomiarów czystych i zabrudzonych paneli...

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  • Implementation of the Boundary Element Method to Two-Dimensional Heat Transfer with Thermal Bridge Effects

    Publication

    The work presents an application of the boundary element method applied to a two-dimensional conductive heat transfer. The algorithm of the method is explained and its advantages are outlined. Green's function as a fundamental solution for Poisson's equation in two dimensions was used and the direct approach was applied. The presented results concern building construction elements as typical cases of thermal bridges. Some properties...

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  • Multiregional PI control strategy for dissolved oxygen and aeration system control at biological wastewater treatment plant

    Publication

    - Year 2012

    The dissolved oxygen is a key parameter for biological processes at wastewater treatment plant. The dissolved oxygen tracking problem is one of the most complex and fundamental issue of biological processes. The paper proposes a new multiregional control strategy for dissolved oxygen tracking problem. The aeration system is included in overall control structure. The control mechanism within the operating point area is based on...

  • Calculation methods of interaction of electromagnetic waves with objects of complex geometries

    Publication

    - TASK Quarterly - Year 2016

    Modeling of the electromagnetic interaction with different homogeneous or inhomo-geneous objects is a fundamental and important problem. It is relatively easy to solve Maxwellequations analytically when the scattering object is spherical or cylindrical, for example. How-ever, when it loses these properties all that is left for us is to useapproximation models, to ac-quire the solution we need. Modeling of complex, non-spherical,...

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  • Symmetrical power line conditioner - basic properties

    Publication

    - Year 2005

    In this paper the basis of analytical modelling of the UPQC arrangements (Unified Power Quality Conditioner) in d-q rotating coordinates, as well as select results of investigations conducted on the simplified small power laboratory model, were talked over. In short form power balance as well as fundamental dependences and analytical model with regard of decoupling circuits, were investigated. Applied method for DC link capacitance...

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  • Hybrid stepless distribution transformer with four-quadrant AC/DC/AC converter at low voltage side - simulation tests

    Publication

    The article presents the work of the stepless hybrid distribution transformer (HT), as an alternative to the so far applied Automatic Voltage Regulator (AVR) solutions, used to control the voltage in the power system in terms of the fundamental harmonic. The HT is a combination of a conventional distribution transformer and an AC/DC/AC converter connected in series with the transformers secondary winding. In the work the basic...

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  • Modeling and experimental investigation of the small UPQC systems

    Publication

    - Year 2005

    In this paper the basis of analytical modelling of the UPQC arrangements (Unified Power Quality Conditioner) in d-q rotating coordinates, as well as select results of investigations conducted on the simplified small power laboratory model were talked over. In short form power balance as well as fundamental dependences and analytic model with regard of decoupling circuits were investigated. Applied method for DC link capacity selection...

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  • Fluctuation-Enhanced Sensing (FES): A Promising Sensing Technique

    Publication

    - Applied Sciences-Basel - Year 2020

    Fluctuation-enhanced sensing (FES) is a very powerful odor and gas sensing technique and as such it can play a fundamental role in the control of environments and, therefore, in the protection of health. For this reason, we conduct a comprehensive survey on the state-of-the-art of the FES technique, highlighting potentials and limits. Particular attention is paid to the dedicated instrumentation necessary for the application of...

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  • High Dynamic Range Microwave Displacement and Rotation Sensors Based on the Phase of Transmission in Groove Gap Waveguide Technology

    This research is focused on the design and realization of displacement sensors in gap waveguide technology. It is shown that with a small but fundamental change in the structure of a conventional gap waveguide, a linear displacement can be sensed. To this end, a unique feature of gap waveguides, i.e. the fact that no electrical connection between the top and bottom parts of the gap waveguide is required, is used. It is further shown...

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  • Marcinkiewicz Averages of Smooth Orthogonal Projections on Sphere

    We construct a single smooth orthogonal projection with desired localization whose average under a group action yields the decomposition of the identity operator. For any full rank lattice \Gamma ⊂ R^d , a smooth projection is localized in a neighborhood of an arbitrary precompact fundamental domain R^d / \Gamma. We also show the existence of a highly localized smooth orthogonal projection, whose Marcinkiewicz average under the...

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  • Designing intranet portals as electronic workplaces

    Publication

    - Year 2007

    This paper highlights the most important requirements for developing intranet portals, especially in the areas of user interface ergonomics and usability. In specifying relevant usability requirements both perspectives are considered: of company employees and of executives. Best practices are reviewed, regarding successes and failures in intranet absorption, basing on the results on recent research in a number of surveyed Polish...

  • Modeling and control of a redundantly actuated variable mass 3RRR planar manipulator controlled by a model-based feedforward and a model-based-proportional-derivative feedforward–feedback controller

    Publication

    - MECHATRONICS - Year 2016

    In the paper, dynamics of a complex mechatronics system is considered. A redundantly actuated planar manipulator is the base of the mechanical part of it. It is a 3RRR 1 platform based parallel manipulator. To control its trajectory, a model-based feedforward controller is employed. Three aspects are fundamental in the presented investigations. The first focus is on development of an accurate numerical model used to solve the inverse...

  • Nonlinear control of five phase induction motor with synchronized third harmonic flux injection

    Publication

    The paper deals with the novel control system for five phase induction motor (IM) that enables the injection of the rotor flux 3rd harmonic component. Two multiscalar models are transformed from the 1-1 and 2-2 vector models developed in the 1st and 3rd harmonic planes. Based on the obtained multiscalar models the synthesis of dual multiscalar control is established. The obtained two multiscalar control systems can independently...

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  • Establishing the allosteric mechanism in CRISPR‐Cas9

    Publication

    Allostery is a fundamental property of proteins, which regulates biochemical information transfer between spatially distant sites. Here, we report on the critical role of molecular dynamics (MD) simulations in discovering the mechanism of allosteric communication within CRISPR‐Cas9, a leading genome editing machinery with enormous promises for medicine and biotechnology. MD revealed how allostery intervenes during at least three...

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