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Search results for: DECISIONAL DNA SET OF EXPERIENCE KNOWLEDGE STRUCTURE KNOWLEDGE REPRESENTATION KNOWLEDGE ENGINEERING DECISION MAKING
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Frameworks for uncertainly representation in risk assessments
PublicationArtykuł dotyczy wybranych zagadnień związanych z niepewnością w ilościowych obliczeniach analizy ryzyka. Problem ten stał się bardzo istotny, ponieważ wystąpiły wymagania w określaniu niepewności w procedurach obliczeń ryzyka.Dyskutuje się potencjalne źródła niepewności oraz dokonuje przeglądu teoretycznych ram do modelowania niepewności. Dla złożonych systemów ryzyka proponuje się obliczenia przedziałowo (rozmyto) probabilistyczne,...
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Fusion of DNA-binding domain of Pyrococcus furiosus ligase with TaqStoffel DNA polymerase as a useful tool in PCR with difficult targets
PublicationThe DNA coding sequence of TaqStoffel polymer- ase was fused with the DNA-binding domain of Pyrococcus furiosus ligase. The resulting novel recombinant gene was cloned and expressed in E. coli. The recombinant enzyme was purified and its enzymatic features were studied. The fusion protein (PfuDBDlig-TaqS) was found to have enhanced processivity as a result of the conversion of the Taq DNA polymerase from a relatively low processive...
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Selection of derivatisation agents for chlorophenols determination with multicriteria decision analysis
PublicationThe paper shows very systematic method of selection of derivatisation agents for a given group of analytes. In this study 8 derivatisation agents are assessed for their capability to derivatise 8 chlorophenols. Multicriteria decision analysis is used to combine many objectives of derivatisation agents selection into single, easy to be interpreted numerical value. Three basic analyses were performed to obtain rankings with the aims...
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MAKING OF FERROMAGNETIC ELLIPTICAL SHELL IN TRANSVERSE MAGNETIC
PublicationA ferromagnetic object, located in the Earth’s magnetic field, changes its distribution. Through measuring such disturbances, one can locate the object and destroy it. To conceal the object, a special winding is placed inside its ferromagnetic shell, and its task is to eliminate the disturbances in the distribution of the Earth’s magnetic field.
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A framework for accelerated optimization of antennas using design database and initial parameter set estimation
PublicationThe purpose of this paper is to exploit a database of pre-existing designs to accelerate parametric optimization of antenna structures is investigated. Design/methodology/approach The usefulness of pre-existing designs for rapid design of antennas is investigated. The proposed approach exploits the database existing antenna base designs to determine a good starting point for structure optimization and its response sensitivities....
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Analiza decyzyjna/Decision analysis
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Phylogenetic trees of genus Oncidium Sw. based on analysis of DNA sequences
Open Research DataGenus Oncidium Sw. is widely regarded as a polyphiletic, and the taxonomic boundaries between him and such genera as Odontoglossum Kunth. or Miltonia Lindley remain blurred. The goal of the study was to determine the phylogenetic relationships within the genus Oncidium s.lato based on the DNA sequences analysis. The correlation between molecular data...
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The distributed model predictive controller for the nuclear power plant turbo-generator set
PublicationTypically there are two main control loops with PI controllers operating at each turbo-generator set. In this paper a distributed model predictive controller DMPC, with local QDMC controllers for the turbine generator, is proposed instead of a typical PI controllers. The local QDMC controllers utilize step-response models for the controlled system components. These models parameters are determined based on the proposed black-box...
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Engineering Challenges in the Design of Cochlear Implants
PublicationHearing aids such as cochlear implants have been used by both adults and children for a long time. In addition, cochlear implants are used by patients who have severe hearing loss either by birth or after an accident. This paper aims to investigate the engineering challenges bounding the design of cochlear implants and present its possible solution...
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Set-Valued and Variational Analysis
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May dithiophosphoric acid participate in the set process?
PublicationZastosowano otrzymane S-tioacyloditiofosforany jako odczynniki tioacylujące do syntezy kwasów tiohydroksamowych. Dla większości N-alkilohydroksyloamin produktem tej reakcji były żądane kwasy tiohydroksamowe. Natomiast gdy substratem jest hydroksyloamina zawierająca duży objętościowo podstawnik na atomie azotu lub gdy posiada dwa podstawniki na atomie azotu w reakcji tej tworzą się wyłącznie odpowiednie O-tioacylohydroksyloaminy....
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Application of gaze tracking technology to quality of experience domain
PublicationA new methodological approach to study subjective assessment results employing gaze tracking technology is shown. Notions of Human-Computer Interaction (HCI) and Quality of Experience (QoE) are shortly introduced in the context of their common application. Then, the gaze tracking system developed at the Multimedia Systems Department (MSD) of Gdansk University of Technology (GUT) is presented. A series of audio-visual subjective...
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Sound engineering as our commitment to its creators in Poland
PublicationSound engineering is an interdisciplinary and rapidly expanding domain. It covers many aspects, such as sound perception, studio and sound mastering technology, music information retrieval including content-based search systems and automatic music transcription frameworks, sound synthesis, sound restoration, electroacoustics, and other ones constituting multimedia technology. Moreover, machine learning methods applied to the topics...
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state aid for broadband infrastructure
Open Research DataThe dataset encompasses a choice of important legal acts, a list of selected bibliography, and a list of important individual sentences issued on the topic of state aid for building the infrastructure and rendering of broadband services during the period 2007-2013 and 2014-2020, as well as beyond, in the EU Member States. Thanks to that the reader gets...
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Early models of DNA damage formation
PublicationPrzeanalizowano jedne z pierwszych modeli opisujących uszkodzenia nici DNA. Przeanalizowano uszkodzenia powstające w pojedynczych i podwójnych niciach, pod wpływem czynników fizycznych i chemicznych.
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Isoform-specific inhibition of DNA topoisomerase II as the mechanism of action of novel anticancer agent C-1305
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Real-time isothermal DNA amplification monitoring in picoliter volumes using an optical fiber sensor
PublicationRolling circle amplification (RCA) of DNA can be considered as a great alternative to the gold standard polymerase chain reaction (PCR), especially during this pandemic period, where rapid, sensitive, and reliable test results for hundreds of thousands of samples are required daily. This work presents the first research to date on direct, real-time and label-free isothermal DNA amplification monitoring using a microcavity in-line...
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60th anniversary of Department of Manufacturing Engineering and Automation
PublicationThe paper presents the outline history of Department of Manufacturing Engineering and Automation of the Gdansk University of Technology over the span of 60 years - throughout the period 1945-2006.
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Toolchain Modeling: Comprehensive Engineering Plans for Industry 4.0
PublicationThe fourth industrial revolution (Industry 4.0) elevates the complexity and autonomy of industrial systems and engineering environments to levels not seen before. The novel challenges involve not only the software running on the partaking autonomous devices, but also architectural considerations and the technological infrastructure around the entire engineering process. In this paper, complementing the trends in industrial systems...
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Effect of osmolytes of different type on DNA behavior in aqueous solution. Experimental and theoretical studies
PublicationOsmolytes, the small organic molecules accumulated in cells under environmental stress, can modulate the stability of biopolymers such as proteins and DNA. In spite of many years of research, there is no established molecular mechanism of the influence of osmolytes on DNA structure. Here, we used two model osmolytes that denature (urea) or stabilize (trimethylglycine, TMG) proteins to study their effect on DNA in aqueous solutions...
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DECISION SCIENCES
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Decision Analysis
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MANAGEMENT DECISION
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THEORY AND DECISION
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Gravity-related research (Engineering and Management of Space Systems) 21/22
e-Learning CoursesThe goal of the subject is to extend of the knowledge gained in the framework of general mechanics (statics, kinematics, dynamics). Students will be familiarized with the description of the kinematics and dynamics of motion in typical gravity-related research conditions (microgravity in parabolic flights, drop towers, sounding rockets) as well as gravity-related research platforms, its opportunities and limitations. Additionally,...
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Development of Education Tomorrow’s Engineers at the Faculty of Mechanical Engineering in GUT
PublicationPaper presents educational activity of Faculty of Mechanical Engineering of the Gdańsk University of Technology. Faculty of Mechanical Engineering is one of the largest departments of the Gdańsk University of Technology (GUT), currently educating about 3 000 student. The Faculty of Mechanical Engineering offers studies in different areas: Mechanical Engineering, Medical and Mechanical Engineering, Materials Engineering, Mechatronic,...
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A Survey on Identifying and Addressing Business Analysis Problems
PublicationDespite the growing body of knowledge on requirements engineering and business analysis, these areas of software project are still considered problematic. The paper focuses on problems reported by business analysts and on applicability of available business analysis techniques as solutions to such problems. A unified set of techniques was developed on the basis of 3 industrial standards associated with IIBA, REQB and IREB certification...
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Scattering by a set of pseudochiral cylinders
PublicationAnaliza rozpraszania fali elektomagnetycznej na układzie cylindrów wykonanych z materiału pseudochiralnego. Analiza obejmuje problemy zamknięte (złącza falowodowe) i otwarte (rozpraszanie w wolnej przestrzeni). Analiza bazuje na metodzie dopasowania rodzajów i zmodyfikowanej procedurze iteracyjnej rozpraszania fali e-m.
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UE regional state aid for territories with low standard of living
Open Research DataThe dataset encompassed a choice of important legal acts, a list of selected Polish bibliography and a list of important individual decisions issued on the topic of regional state aid ( for investment purposes) in Poland in the periods 2007- 2013 and 2014- 2020. Thanks to that the reader gets the possibility to acquire basic knowledge on the abovementioned...
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Surface irregularities as a complex signal of tool representation together with uneven displacement in respect to the workpiece
PublicationIn a dynamic machining process, distortion in surface irregularity is a very complex phenomenon. Surface irregularities form a periodic representation of the tool profile with various kinds of disturbance in a broad range of changes in the height and length of the profile. To discern these irregularity disturbances, interactions of the tool in the form of changes perpendicular and parallel relative to the workpiece were analyzed...
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Effect of heat treatment on the diffusion intermixing and structure of the Cu thin film on Si (111) substrate: a molecular dynamics simulation study
PublicationThis work is devoted to the study of the diffusion process at the interface between copper films with a thickness of 2, 3, 4, 7 and 10 atomic monolayers and silicon substrate by molecular dynamics simulation method. For this purpose, the variation of the concentration of copper and silicon along the perpendicular direction to the interface was investigated. An analysis of the density profile along this direction made it possible...
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Green Polymer Nanocomposites for Skin Tissue Engineering
PublicationFabrication of an appropriate skin scaffold needs to meet several standards related to the mechanical and biological properties. Fully natural/green scaffolds with acceptable biodegradability, biocompatibility, and physiological properties quite often suffer from poor mechanical properties. Therefore, for appropriate skin tissue engineering and to mimic the real functions, we need to use synthetic polymers and/or additives as complements...
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Badanie i porównanie zdolności wybranych leków i związków przeciwnowotworowych do międzyłańcuchowego sieciowania DNA mitochondrialnego i jądrowego w komórkach nowotworowych
PublicationCelem pracy było zbadanie zdolności przeciwnowotworowych związków do indukowania międzyłańcuchowych wiązań sieciujących DNA mitochondrialne w ludzkich komórkach nowotworowych oraz porównanie ze zdolnością do sieciowania DNA jądrowego. Pochodna 4-metylo-1-nitroakrydyny C-1748, Ledakrin i mitomycyna C wykazują zdolność do sieciowania mtDNA i jDNA w komórkach raka okrężnicy HCT-8 w sposób zależny od dawki; C-1748 w komórkach raka...
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Crystal structure and electronic structure of CePt2In7
PublicationWe report a corrected crystal structure for the CePt2In7 superconductor, refined from single crystal x-ray diffraction data. The corrected crystal structure shows a different Pt–In stacking along the c-direction in this layered material than was previously reported. In addition, all of the atomic sites are fully occupied with no evidence of atom site mixing, resolving a discrepancy between the observed high resistivity ratio of...
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The concept of experience marketing - examples of practical application (PG_0005962), W, International Design Engineer, sem. 2, zimowy 2023/24
e-Learning CoursesCelem przedmiotu jest zaznajomienie studentów z koncepcją marketingu doświadczeń, będącego coraz częściej obligatoryjną podstawą innowacyjnych strategii marketingowych przedsiębiorstw oraz ukazanie praktycznego zastosowania niniejszej idei (zarządzanie doświadczeniami, strategiczne moduły doświadczeń, mapowanie podróży klienta i pracownika firmy). The aim of the course is to familiarize students with the concept of experience...
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Analysis of induction of DNA DSBs on telomeres in A549 cells
Open Research DataData consist of an analysis of DNA DSBs on telomeres. A549 were treated with compounds (TXT4, MTX, DMSO) at IC90 concentration for the indicated time. Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss; Dresden, Germany) equipped with an Airyscan detector using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss)....
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Measuring the density of DNA films using ultraviolet-visible interferometry
PublicationIn order to determine a proper value for the density of dry DNA films we have used a method based upon the measurement of interference effects in transmission spectra of thin DNA layers. Our results show that the methodology is effective and the density of DNA in this state, 1.407 g/cm3, is much lower than the commonly used 1.7 g/cm3. Obtaining accurate values for the DNA film density will allow the optical constants for DNA to...
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Developments in manufacturing engineering and machining process planning
PublicationCurrent research conducted in the Department of Manufacturing Engineering and Automation is presented in the paper. This includes: abrasive cutting off, grinding with lapping kinematics, rapid prototyping and machining procrss planning. Experimental results and computer simulation are presented and analysed.
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Mariusz Jaczewski dr inż.
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A vector-enzymatic DNA fragment amplification-expression technology for construction of artificial, concatemeric DNA, RNA and proteins for novel biomaterials, biomedical and industrial applications
PublicationA DNA fragment amplification/expression technology for the production of new generation biomaterials for scientific, industrial and biomedical applications is described. The technology enables the formation of artificial Open Reading Frames (ORFs) encoding concatemeric RNAs and proteins. It recruits the Type IIS SapI restriction endonuclease (REase) for an assembling of DNA fragments in an ordered head-to-tail-orientation. The...
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Swarm Algorithms in Modern Engineering Optimization Problems
PublicationComplexity of today engineering problems is constantly increasing. Scientists no longer are facing issues, for which simple, mathematical programming methods are sufficient. Issues like autonomic vehicle navigation or classification are considered to be challenging, and although there exist valid means to solve them, in some cases there still is some place for improvement. With emergence of a new type of optimization techniques...
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Intercalation complex of imidazoacridinone C-1311, a potential anticancer drug, with DNA helix d(CGATCG)2: stereostructural studies by 2D NMR spectroscopy.
PublicationImidazoacridinone C-1311 (Symadex®) is a powerful antitumor agent, which successfully made its way through the Phase I clinical trials and has been recommended for Phase II few a years ago. It has been shown experimentally that during the initial stage of its action C-1311 forms a relatively stable intercalation complex with DNA, yet it has shown no base-sequence specificity while binding to DNA. In this paper, the d(CGATCG)2:C-1311...
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SOFTWARE-PRACTICE & EXPERIENCE
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Strengths of studying at Gdańsk University of Technology - the year 2011
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates from the year 2011 on the strengths of studying at Gdańsk University of Technology. The survey was conducted in 2013, two years after the respondents obtained graduate status. The research sample included 615 respondents. To summarize, among the strengths of studying...
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Strengths of studying at Gdańsk University of Technology - the year 2013
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates from the year 2013 on the strengths of studying at Gdańsk University of Technology. The survey was conducted in 2015, two years after the respondents obtained graduate status. The research sample included 1777 respondents. To summarize, among the strengths of...
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Strengths of studying at Gdańsk University of Technology - the year 2012
Open Research DataThe dataset includes data from the survey on the Gdańsk University of Technology graduates from the year 2012 on the strengths of studying at Gdańsk University of Technology. The survey was conducted in 2014, two years after the respondents obtained graduate status. The research sample included 629 respondents. To summarize, among the strengths of studying...
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Zarządzanie wiedzą w małych przedsiębiorstwach oferujących wiedzochłonne usługi biznesowe
PublicationCelem artykułu jest przedstawienie praktyk zarządzania wiedzą oraz czynników wpływających na sukces, bądź porażkę w ich wdrażaniu na podstawie badania jakościowego przeprowadzonego w trzech firmach działających na terenie województwa pomorskiego. Firmy te należą do sektora małych i średnich przedsiębiorstw oraz oferują wiedzochłonne usługi biznesowe (knowledge-intensive business services – KIBS). W artykule podjęto próbę odpowiedzi...
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Making agile retrospectives more awesome
PublicationAccording to the textbook [23], Scrum exists only in its entirety, where every component is essential to Scrum’s success. However, in many organizational environments some of the components are omitted or modified in a way that is not aligned with the Scrum guidelines. Usually, such deviations result in missing the full benefits of Scrum [24]. Thereby, a Scrum process should be frequently inspected and any deviations should be...
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Quantitative Storytelling in the Making of a Composite Indicator
PublicationThe reasons for and against composite indicators are briefly reviewed, as well as the available theories for their construction. After noting the strong normative dimension of these measures—which ultimately aim to ‘tell a story’, e.g. to promote the social discovery of a particular phenomenon, we inquire whether a less partisan use of a composite indicator can be proposed by allowing more latitude in the framing of its construction....
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The Hybrid Fuzzy - SOEKS Approach to the Polish Internet Mortgage Market
PublicationThe paper presents the hybrid fuzzy- SOEKS approach to the Polish Internet mortgage market, which is treated as an example of a fast changing market. Firstly, the market and market problems are described. Then, the first approach to the market problems is presented: the complete fuzzy model which was built basing on the rules. The fuzzy model is presented on one real data case. Next, the new approach, called Set of Experience Knowledge...