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Search results for: EPIGENETIC REMODELLING
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Bulletin of the South Ural State University Series-Mathematical Modelling Programming & Computer Software
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Tadeusz Stolarski prof. dr hab. inż.
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Michał Mazur dr inż.
PeopleAktualne zainteresowania inżynieria mechaniczna, robotyka, drgania mechaniczne, analiza modalna, sterowanie, systemy czasu rzeczywistego Wybrane publikacje Kaliński K., Galewski M., Mazur M., Chodnicki M, 2017, Modelling and Simulation Of A New Variable Stiffness Holder for Milling Of Flexible Details, Polish Maritime Research, vol 24, ss. 115-124 Kaliński K. J., Mazur M.: Optimal control at energy performance index of the mobile...
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Rafał Lech dr hab. inż.
PeopleIEEE Senior Member #92122578 Rafal Lech was born in Elblag, Poland, in 1977. He received the M.Sc.E.E. and Ph.D. degrees (with honors) from the Gdansk University of Technology, Gdansk, Poland, in 2001 and 2007, respectively. He is currently with the Faculty of Electronics, Department of Microwave and Antenna Engineering, Telecommunications and Informatics, Gdansk University of Technology. His main research interests are electromagnetic-wave...
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Wave energy attenuation in fields of colliding ice floes. Part A: Discrete-element modelling of dissipation due to ice–water drag
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Population modelling of <i>Acartia</i> spp. in a water column ecosystem model for the South-Eastern Baltic Sea
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AIR QUALITY INFLUENCE OF SELECTED POLLUTANTS EMITTED FROM A FIRE OF 300 MG OF MUNICIPAL WASTE ON AMBIENT AIR QUALITY: AN EXAMPLE OF MODELLING WITH HYSPLIT
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Chemometric analysis of bio-inspired micellar electrokinetic chromatographic systems – modelling of retention mechanism and prediction of biological properties using bile salts surfactants
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The resistance investigation of the marine engine exchaust valve using the modelling chamber = Badania odporności zaworów wylotowych silnika okrętowego w komorze modelowej
PublicationWe współczesnej technice szereg części urządzeń i instalacji pracuje w długich okresach czasu i w złożonych warunkach obciążenia mechanicznego, termicznego i chemicznego. Próby wprowadzenia nowych rozwiązań technicznych muszą być poprzedzone szczegółowymi badaniami, które stwierdzą przydatność do konkretnych zastosowań. Problemem występującym w przemyśle okrętowym, a dokładniej w procesie eksploatacji silników okrętowych jest trwałość...
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Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies
PublicationSyntetyczne antracenodionowe leki przeciwnowotworowe, w przeciwieństwie do antybiotyków antracyklinowych, charakteryzują się słabym wytwarzaniem wolnych rodników w układach z dehydrogenazą NADH. Wyniki prezentowane w artykule wskazują, że ani potencjał redukcyjny, ani konformacja łańcuchów bocznych, ani energie orbitali granicznych (LUMO i HOMO) nie determinują zdolności antracenedionów do stymulacji wytwarzania reaktywnych form...
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Portico Farmhouses of the Vistula Delta: Architecture, Current State and Finite Element Modelling of Timber Roof Truss under Material and Cross-section Uncertainty
PublicationThe article focuses on the oldest surviving I-type portico houses located in the Vistula Delta, which were built in the 17th and 18th centuries. The study describes the houses’ origins, structure, details of roof structures and technical condition, and it also includes numerical modelling of a roof truss and its mechanical analysis. Numerical models of the roof trusses are defined and analysed by means of the finite element method....
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Generating actionable evidence from free-text feedback to improve maternity and acute hospital experiences: A computational text analytics & predictive modelling approach
PublicationBackground Patient experience surveys are a key source of evidence for supporting decision-making and quality improvement in healthcare services. These surveys contain two main types of questions: closed and open-ended, asking about patients’ care experiences. Apart from the knowledge obtained from analysing closed-ended questions, invaluable insights can be gleaned from free-text data. Advanced analytics techniques are increasingly...
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Modelling of SO2 and NOx Emissions from Coal and Biomass Combustion in Air-Firing, Oxyfuel, iG-CLC, and CLOU Conditions by Fuzzy Logic Approach
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A constitutive model for concrete based on continuum theory with non-local softening coupled with eXtended Finite Element Method. Computational Modelling of Concrete Structures,
PublicationArtykuł omawia model połączony ciągły-nieciągły do modelowania stref lokalizacji i rys w betonie niezbrojonym. Obliczenia wykonano stosując rozszerzoną metodę elementów skończonych. Wyniki numeryczne porównano z doświadczeniami.
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Michał Małafiejski dr hab. inż.
PeopleMichał Małafiejski was born in 1975. He received the M.Sc. in computer science (in 1999). He received the Ph.D. in computer science in 2002 and habilitation in the same area in 2014. He works as associate professor in Department of Algorithms and Modelling of Systems. He is the author or coauthor of many papers related to theoretrical computer science. Main area of his research is the design of efficient algorithms and the analysis...
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Mieczysław Brdyś prof. dr hab. inż.
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DNAffinity: a machine-learning approach to predict DNA binding affinities of transcription factors
PublicationWe present a physics-based machine learning approach to predict in vitro transcription factor binding affinities from structural and mechanical DNA properties directly derived from atomistic molecular dynamics simulations. The method is able to predict affinities obtained with techniques as different as uPBM, gcPBM and HT-SELEX with an excellent performance, much better than existing algorithms. Due to its nature, the method can...
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International Journal of Modelling, Identification and Control
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MODELLING AND SIMULATION IN MATERIALS SCIENCE AND ENGINEERING
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Modelling of mutual coupling in microstrip antenna arrays fed by microstrip line. Modelowanie sprzężenia w szykach anten mikropaskowych zasilanych przez linie mikropaskowe.
PublicationPrzedstawiono wyniki modelowania sprzężenia pomiędzy prostokątnymi radiatorami mikropaskowymi w szyku liniowym anten zasilanych przez linie mikropaskowe. Zaproponowano schemat zastępczy sprzężenia w postaci kombinacji linii transmisyjnych wraz z sękami zwartymi i rozwartymi. Pokazano, że schemat taki dobrze modeluje sprzężenie w wąskim pasmie częstotliwości ok. 4%. Wyniki modelowania sprawdzono eksperymentalnie poprzez pomiary...
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Modelling of migration and fate of selected persistent organic pollutans in the Gulf of Gdańsk and the Vistula catchment (Poland): selected results from the EU ELOISE EuroCat project
PublicationW publikacji przedstawiono wyniki pomiarów poziomu stężeń wybranych trwałych zanieczyszczeń organicznych w próbkach wody pobranych z Zatoki Gdańskiej i Wisły. Zamieszczono także opis modelu migracji zanieczyszczeń Co Z Mo - POP. Pokazano także migrację wybranych heksachlorobenzenów i polichlorowanych bifenyli w ekosystemie Zatoki Gdańskiej i Wisły.
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Numeryczne modelowanie prędkości płynięcia warstw blachy bimetalowej w procesie walcowania = The numerical modelling of the layers flow velocity in bimetal plates rolling proces
PublicationW pracy przedstawiono wyniki obliczeń numerycznych dotyczących procesu asymetrycznego walcowania blach bimetalowych 18G2A+1H13.
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St. Adalberd church 3D point model
Open Research DataResearch data show the church of St. Adalbert in Gdansk, Poland. Two layers are presented in the .zip file: one represents the laser scanning result, the second represents the point cloud from 36 photogrammetry images from the UAV system. The aligned point clouds formed the basis to create the high-resolution 3D model. Reference data are laser scanning...
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Joanna Raczek dr inż.
PeopleEmployment 2003 -- 2019: Faculty of Applied Physics and Mathematics, Gdańsk University of Technology. 2019 - present: Faculty of Electronic, Informatics and Telecominications, Gdańsk University of Technology. Education May 2007: Doctor of Philosophy in Mathematics, University of Gdańsk. Doctoral dissertation: "Paired domination and doubly domination in graphs". Supervisor: dr hab. Jerzy Topp. 2000 -- 2004 Bachelor of Science...
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Modelowanie kratownicy z kształtowników giętych na zimno z mimośrodami dodatnimi w węźle = Modelling of truss with cold-formed section and positive eccentricyty in the node.
PublicationThe topic of this research is establishing load-carrying capacity of compressed and tensed chords of trusses made of cold-formed open cross-sections. Occurrence of bending in the truss’ chord is the result of specific production technology assumed by the designer and producer of lattice girder’s systems. The aim of this research is to present methodology of conduct while creating numerical models that best depict the behaviour...
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Wave energy attenuation in fields of colliding ice floes &#8211; Part 1: Discrete-element modelling of dissipation due to ice&#8211;water drag
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Two-dimensional vertical Reynolds-averaged naviers-stokes equations versus one-dimensional Saint-Venant model for rapidly varied open channel water flow modelling
PublicationPrzedstawiono dwa modele przepływu wody ze swobodną powierzchnią -płaski pionowy model Reynoldsa i model de Saint-Venanta.Do rozwiązania równań pierwszego modelu zastosowano schemat SIMPLE oraz wykorzystano metodę cząstek znaczonych MAC do wyznaczania swobodnej powierzchni wody. Równania Saint-Venanta rozwiązano metodą objętości skończonych. Obydwa modele zastosowano do symulacj zjawiska typu katastrofa zapory. Porównano wyniki...
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Effect of particle size and weight fraction of SiC on the mechanical, tribological, morphological, and structural properties of Al-5.6Zn-2.2Mg-1.3Cu composites using RSM: fabrication, characterization, and modelling
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Targeting Spike‐ACE2 Interface of SARS‐CoV‐2 and its Omicron Variant: A Comparative Screening of Potential Inhibitors for Existing and Anticipating Variants Using Molecular Modelling Approach
PublicationThe recent COVID pandemic has shown major impact on public health and economic crisis. Despite the development of many vaccines and drugs against the severe acute respiratory syndrome (SARS) coronavirus 2, the pandemic still persists. The continued spread of the virus is largely driven by the emergence of viral variants such as α, β, γ, delta, epsilon spike, omicron and its subvariants (BA.1,2,3) which can evade the current vaccines...
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3D modelling of beach topography changes caused by the tombolo phenomenon using terrestrial laser scanning (TLS) and unmanned aerial vehicle (UAV) photogrammetry on the example of the city of Sopot
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Agnieszka Witkowska dr hab. inż.
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Tomasz Zubowicz dr inż.
PeopleTomasz Zubowicz has received his M.Sc. Eng. degree in Control Engineering from the Faculty of Electrical and Control Engineering at the Gda{\'n}sk University of Technology (GUT) in $2008$. He received his Ph.D. Eng. (Hons.) in the field of Control Engineering from the same faculty in $2019$. In $2012$ he became a permanent staff member at the Department of Intelligent Control and Decision Support Systems at GUT and a member of...
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Robert Janczewski dr hab. inż.
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Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains
PublicationAims We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. Materials and Methods Global DNA methylation profiling was performed in ear pinnae, bone marrow, spleen, liver, heart from uninjured adult females of the MRL/MpJ and C57BL/6J and BALB/c. Results and conclusion A number of differentially methylated regions distinguishing between...
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The methylome and transcriptome of fetal skin: implications for scarless healing
PublicationAim: Fetal skin is known to heal without scarring. In mice, the phenomenon is observed until the 16–17 day of gestation – the day of transition from scarless to normal healing. The study aims to identify key methylome and transcriptome changes following the transition. Materials & methods: Methylome and transcriptome profiles were analyzed in murine dorsal skin using microarray approach. Results & conclusion: The genes associated...
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In silico modelling for predicting the cationic hydrophobicity and cytotoxicity of ionic liquids towards the Leukemia rat cell line, Vibrio fischeri and Scenedesmus vacuolatus based on molecular interaction potentials of ions
PublicationIn this study we present prediction models for estimating in silico the cationic hydrophobicity and the cytotoxicity (log [1/EC50]) of ionic liquids (ILs) towards the Leukemia rat cell line (IPC-81), the marine bacterium Vibrio fischeri and the limnic green algae Scenedesmus vacuolatus using linear free energy relationship (LFER) descriptors computed by COSMO calculations. The LFER descriptors used for the prediction model (i.e....
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Combination of terrestrial laser scanning and UAV photogrammetry for 3D modelling and degradation assessment of heritage building based on a lighting analysis: case study—St. Adalbert Church in Gdansk, Poland
PublicationThe construction of the St. Adalbert Church in Gdansk dates to 1310. It is a church of rich history and great historical value, and its care is challenging. In this study, the combination of unmanned aerial vehicle (UAV) photogrammetry and terrestrial laser scanning (TLS) was used to accurately build a 3D model of the church. Together with the collected historical inventory documentation, the historic building information model...
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International Journal of Mathematical Modelling and Numerical Optimisation
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Results of electrical voltage measurements in reactors - part 1
Open Research DataResults of electric voltage measurements in six reactors using various plantings. These are the results of the project: Integrated approach 3M (Macrophytes-Microbiome-Modelling) to elucidate mechanisms of bioenergy production and micropollutants transformation in Floating Treatment Wetlands combined with Microbial Fuel Cells.
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Business process modelling
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Business process modelling
e-Learning CoursesWelcome to the Business Process Modeling course! We will travel together among the business processes world and its modeling with the BPMN ;) I hope it will be valuable for your future. See you soon, Marzena Grzesiak
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Piotr Andrzej Mironowicz dr inż.
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Krzysztof Pastuszak mgr inż.
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Filip Kutt dr inż.
PeopleFilip Kutt was born in Gdansk, Poland. He received the M.Sc., PhD, degrees in electrical engineering in 2007 and 2013, respectively, all from Gdansk University of Technology (GUT) Poland. He is with GUT since 2007, currently as an Assistant Professor. His main scientific and research interests cover a wide spectrum of mathematical modelling of electrical machines using analytical modelling and FEM-based computations.
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PROBLEMS OF THE STARTING AND OPERATING OF HYDRAULIC COMPONENTS AND SYSTEMS IN LOW AMBIENT TEMPERATURE (PART IV) MODELLING THE HEATING PROCESS AND DETERMINING THE SERVICEABILITY OF HYDRAULIC COMPONENTS DURING THE STARTING-UP IN LOW AMBIENT TEMPERATURE
PublicationDesigners of hydraulically driven machines and devices are obliged to ensure during design process their high service life with taking into account their operational conditions. Some of the machines may be started in low ambient temperature and even in thermal shock conditions (due to delivering hot working medium to cold components). In order to put such devices into operation appropriate investigations, including experimental...
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Jarosław Górski prof. dr hab. inż.
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublicationHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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Cancer immune escape: the role of antigen presentation machinery
PublicationThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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International Conference on Multimedia Modelling
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International Conference on Conceptual Modelling
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