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Search results for: KICKUTH DESIGN
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HDAC Inhibitors: Innovative Strategies for Their Design and Applications
PublicationHistone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...
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THE ROLE OF INFERENCE IN MOBILE MEDICAL APPLICATION DESIGN
PublicationIn the early 21st century, artificial intelligence began to be used to process medical information. However, before this happened, predictive models used in healthcare could only consider a limited number of variables, and only in properly structured and organised medical data. Today, advanced tools based on machine learning techniques - which, using artificial neural networks, can explore extremely complex relationships - and...
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How Good are the Design Tools in Power Electronics?
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Bandpass Filter Design Using Multimode Resonator
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Geometry design in rerfractive capillary optical fibers
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Design of Experiments in metabolomics-related studies: An overview
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Urban design and therapeutic landscapes. Evolving theme.
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A computer system for the complete design of ship propellers
PublicationPraca zawiera opis metody obliczeniowej pozwalającej na zaprojektowanie okrętowej śruby napędowej dla również obliczeniowo wyznaczonego niejednorodnego pola prędkości za kadłubem statku o znanej geometrii i parametrach ruchu. Metoda pozwala na właściwe ujęcie efektu skali i konsekwencji obecności płetwy sterowej za projektowaną śrubą.
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AGENT-BASED APPROACH TO THE DESIGN OF RBF NETWORKS
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Application tool for IP QoS network design
PublicationDespite the fact that differentiated-service-aware network implementation has been a widely discussed topic for quite some time, network design still proofs nontrivial. Well developed software could put an end to network designer's problems. This chapter describes work, which has been aimed at creating a comprehensive network design tool, offering a fair range of functionality and high reliability. The presented tool is able to...
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Influence and selection of basic concepts on ontology design
PublicationOntologies as entities representing individual point of view on surrounding world introduce heterogeneity to knowledge representation. Common set of core concepts can introduce similarity big enough for further interoperability between ontologies. In this paper an experiment is presented proving that despite differences in detail ontologies stay similar in regard of core concepts. During the experiments NOIA methodology enhanced...
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Design of a microrobotic wrist for needle laparoscopic surgery
PublicationThe paper addresses the design of a micro wrist for needle laparoscopic surgery (needlescopy) using MEMS technology and an original 3 degree of freedom, 3D architecture. Advancement in needlescopy drives the development of multi-dof micro-tools 1-2mmin diameter with 3D mobility but standard available fabricationtechniques are for 2.5D structures. The paper discusses thedevelopment steps and design solutions for the realization...
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Towards the value-based design of on-line services
PublicationThe paper identifies economic factors shaping customer bahaviour in on-line services in two interrelated dimensions; (1) economic needs and requirements, relevant to expected benefits and values perceived by customers; (2) technical components, allowing technical realization of on-line services. Technical components were cathegorized into four groups, creating so-called VIPR model: Visual, Interactive, Process and Relationship-relevant...
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Modelling the context of use for Intranet portals design
PublicationIntranet portals in contemporary enterprises affect the way how people work, communicate and build relationships within teams and organizations. Developing high usability in Intranet projects requires analysing context of use and including many additional organizational and cultural factors, normally not present in regular software projects. A modelling framework presented in this paper is useful for analysing context of use for...
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Computer Aided Design of Wood Pellet Machines
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The use of CAD applications in the design of shredders for polymers
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CAD/CAE Applications in Mill’s Design and Investigation
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Active monitoring as cognitive control of grinders design
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Protection System Design of Induction Motor for Industries
PublicationThe fundamental and durable structures of induction motor, as well as their low manufacturing cost, make them popular components in a wide range of current applications. Providing a safety net for employees is a must-have for businesses. This project’s motivation for improvement is to provide industrial motors, lift motors, pumps, and so on with safety. An induction motor’s primary goal is to protect it from problems, such as...
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Protection System Design of Induction Motor for Industries
PublicationThe fundamental and durable structures of induction motor, as well as their low manufacturing cost, make them popular components in a wide range of current applications. Providing a safety net for employees is a must-have for businesses. This project’s motivation for improvement is to provide industrial motors, lift motors, pumps, and so on with safety. An induction motor’s primary goal is to protect it from problems, such as...
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Interactive design system for provisioning of customized houses
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Alternative shaper: a model for automatic design generation
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Design of electromagnetic shields for small electronic units.
PublicationSystemy elektroniczne, które przetwarzają informacje niejawną lub informację chronioną prawem, wymagają nie tylko jej szyfrowania, ale także zastosowania środków i metod minimalizacji ulotu elektromagnetycznego, jaki zawsze towarzyszy elektronicznemu przetwarzaniu informacji. Wymagania dotyczące tłumienia emisji promieniowanej i przewodzonej, w szczególności dotyczące przetwarzania i przesyłania informacji tajnej osiągają poziom...
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Information significance in engineering design processes in shipyards
PublicationW artykule zwrócono uwagę na aspekt zarządzania procesem budowy statku, zarządzania informacją w procesie projektowania oraz znaczeniu systemów informacyjnych w transmisji informacji pomiędzy biurem projektowym a organizacjami współpracującymi. Dzięki jednolitej informacji projektowej we wszystkich fazach projektowania uzyskujemy ciągłość procesu projektowego, eliminację niepotrzebnych kosztów związanych z poprawą błędów oraz lepszą...
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Control theory methods in diagnostic system design
PublicationPraca dotyczy zastosowania wybranych metod teorii sterowania do syntezy al-gorytmów detekcji uszkodzeń. Algorytmy takie, stanowiące istotną gałąźwspółczesnej diagnostyki technicznej obiektów dynamicznych, w swej istocieopierają się na rozwiązaniach odpowiednich zadań odpornego wyznaczania wek-torów resztowych, czyli ważonych błędów oszacowań wyjściadanego obiektu dy-namicznego (nadzorowanego procesu). Na treść pracy...
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Hygienic design of pumps, homogenisers and dampening devices.
PublicationPrzedstawiono wymagania dotyczące materiałów oraz ich przygotowania, a także dla powierzchni wewnętrznych i zewnętrznych urządzeń takich jak pompy, homogenizatory i nawilżacze oraz ich elementów, zwłaszcza wielu typów uszczelnień, ze względu na ich zastosowanie do produkcji żywności w warunkach sanitarno-higienicznych i maksymalne wyeliminowanie zagożeń dla jakości podczas jej wytwarzania w różnorodnych procesach technologicznych.
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Aerated grit chambers hydraulic design equation.
PublicationW pracy zaproponowano metodę wymiarowania piaskowników napowietrzanych. Jej głównymi elementami są wyznaczanie niezbędnej intensywności aeracji ścieków, pola ich prędkości oraz trajektorii cząstek zawiesiny.
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Design of knowledge-based systems in environmental engineering.
PublicationW pracy omawia się konstrukcję iteracyjnie dostrajającego się modelu rozmytego zarządzania przedsięwzięciami informatycznymi, stosowanego do wspomagania wytwarzania systemów opartych na wiedzy. Proponowany model służy w szczególności do zarządzania zmianami finansowania i czasu realizacji projektów dotyczących m.in. systemów wykorzystywanych w (inżynierii) ochronie środowiska. Struktura tego modelu zasadza się na teorii systemów...
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2D inverse method of turbomachinery stage design
Publication1. How 2D model for turbomachinery stages has developed historically. 2. Recent understanding of physical background of 2D model. 3. Curvilinear system of non-orthogonal coordinates in the application to 2D model. 4. Set of basic equations. 5. Closing conditions for the inverse problem. 6. Examples of solutions a)
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Stirling engine design effects on performance indicies.
PublicationW pracy przedstawiono analizę wpływu wybranych parametrów konstrukcyjnych silnika Stirlinga MAC-02 na jego własności eksploatacyjne. Przyjmując maksimum mocy jako kryterium optymalizacji badano jaki wpływ na wybrane wskaźniki jakości (moc i sprawność) oraz optymalizowane parametry konstrukcyjne silnika (wymiary wymiennika cieplnego oraz parametry układu korbowego) mają ograniczenia nałożone na ciepło dostarczane oraz długość...
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Design of knowledge based systems in environmental engineering.
PublicationW pracy omawia się konstrukcję samo narastającego modelu rozmytego zarządzania przedsięwzięciami informatycznymi, stosowanego do wspomagania wytwarzania systemów opartych na wiedzy. Proponowany model służy w szczególności do zarządzania zmianami finansowania i czasu realizacji projektów. Opiera się on na eksperymentalnej regułowej wiedzy, pochodzącej z realizacji zarządzania przedsięwzięciami informatycznymi, na teorii systemów...
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Materials Design for the Titanium Scaffold Based Implant
PublicationThe main objective of here presented research is a design the scaffold/porous titanium(Ti) alloy based composite material demonstrating better biocompatibility, longer lifetime andbioactivity behaviour for load-bearing implants. The development of such material is proposed bymaking a number of consecutive tasks. Modelling the mechanical, biomechanical and biologicalbehavior of porous titanium structure and an elaboration of results...
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Portable Raman spectrometer - design rules and applications
PublicationRaman spectroscopy has become more popular due to its new prospective field applications in forensic sciences, war against terrorism, environment protection and other field chemical analysis. Raman spectrometers can be miniaturised to portable devices and their price is decreasing due to development of optoelectronics components. Unfortunately, this technology has still numerous limitations that influence their design and limit...
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Design and synthesis of new substrates of HtrA2 protease
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Design of precise control systems of industrial plants
PublicationA method for developing precision control systems in industry has been created based on a set of models that take into account the nonlinearity of the reactor model, the nonlinearities of the hydrodynamic regime and the accuracy of the control elements, the nonlinear characteristics and accuracy of the actuators, and the precision of the sensors used. A multidimensional precision control system has been developed for a continuous...
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Novel Design of an Ocean Wave Power Device
PublicationW artykule przedstawiono nowoczesną boję energetyczną o opatentowanej konstrukcji. Omówiono jej konstrukcję oraz przedstawiono problemy konstrukcyjne i badawcze. W ostatniej części artykułu przedstawiono wyniki badań wykonanych na modelu w basenie modelowym.
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Hybrid System for Ship-Aided Design Automation
PublicationA hybrid support system for ship design based on the methodology of CBR with some artificial intelligence tools such as expert system Exsys Developer along with fuzzy logic, relational Access database and artificial neural network with backward propagation of errors.
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Innovative design of hybrid powered inland vessel
PublicationOne of the most demanding task for European countries is rational transportation system taking into account fuel efficient and ecological propulsion. The paper presents innovative design of hybrid powered inland vessel. The most important aspects regarding new design and technical solutions are being presented, including numerical and experimental research on hull form. Combined diesel-electric propulsion supported by solar panel...
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Lighting design for urban revitalization. The case of Poland
PublicationThis paper reflects on the basic research done in the area of public lighting in regard to revitalization processes. The general purpose of this scientific paper is to research a role of an implementation of public lighting design within revitalization frameworks. Referring to a wide spectrum of academic publications, the paper provides an overview of revitalization and public lighting objectives. The emphasize is put on a need...
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Design of horizontal axis wind and water turbines
PublicationThe basic hydrodynamic principles of horizontal axis turbines are presented. Computational methods based on vortex theory for design of such turbines and for calculation of their hydro or aerodynamic characteristics are described in detail. These methods are applicable both to wind and water turbines. The influence of detailed turbine geometry on its characteristics is presented. Several practical computational examples of different...
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Design of M2M Communications Interfaces in Transport Systems
PublicationIn the paper the principle of M2M communications in transport systems is presented. The concept of M2M system architecture is considered. Characteristics of M2M communications for example data transmission, monitoring and other services for transport applications are presented. The problem of communications interfaces design for M2M applications is analysed. Next, the proposal of M2M communication interface for transport applications...
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COMPUTER-AIDED DESIGN OF ORGANOPHOSPHORUS INHIBITORS OF UREASE
PublicationBased on the structure of the most potential inhibitor diamidophosphate, various novel groups of inhibitors were developed by knowledge-based design approach with covalent carbon-phosphorus or carbon-phosphorus-carbon bond to improve hydrolytic stability to inhibit the microbial ureases. Designed compounds were evaluated with 10 (LigScore1, LigScore2, PLP1, PLP2, JAIN, PMF, PMF04, LUDI_1, LUDI_2 and LUDI_3) different scoring functions...
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Safety-based approach in multifunctional building design
PublicationABSTRACT: The modern trend in design of the public buildings is to create multifunctional environments in one building, hosting a variety of functions. Multifunctional buildings entertain large number of visitors. The complexity and vulnerability of this type of public space are the main reasons to use within their design process the performance based approach including the recognition of hazards. Safety and reliability approach...
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A Concept of Mechatronic design for a Surveillance of Dynamic Systems
PublicationW publikacji przedstawiono zastosowanie koncepcji projektowania mechatronicznego w nadzorowaniu systmów dynamicznych. W szczególności są to aktywne nadzorowanie drgań podczas frezowania oraz nadzorowanie ruchu platformy 3-kołowej. Przy tworzeniu opisywanych rozwiązań zastosowano techniki projektowania wirtualnego, symulacjje komputerowe jaki w technice Hardware-in-the-Loop. W pracy zamieszczono także przykładowe wyniki badań eksperymentalnych...
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Design of compound curves adapted to the satellite measurements
PublicationThe paper deals with a novelty related to the design of a region for an alternative railway track direction adequate for mobile satellite measurements. The new approach may become particularly useful in the design of the existing track axis control when the determination of both the main track directions becomes impossible. The only solution in that case is to apply to the geometrical system two circular arcs of a different radius,...
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Design Elements of Affect Aware Video Games
PublicationIn this paper issues of design and development process of affect-aware video games are presented. Several important design aspects of such games are pointed out. A concept of a middleware framework is proposed that separates the development of affect-aware video games from emotion recognition algorithms and support from input sensors. Finally, two prototype affect-aware video games are presented that conform to the presented architecture...
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Optimization issues in distributed computing systems design
PublicationIn recent years, we observe a growing interest focused on distributed computing systems. Both industry and academia require increasing computational power to process and analyze large amount of data, including significant areas like analysis of medical data, earthquake, or weather forecast. Since distributed computing systems – similar to computer networks – are vulnerable to failures, survivability mechanisms are indispensable...
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Design and implementation of GEPON architecture in laboratory testbed
PublicationThis paper presents a proposition of GEPON architecture for the didactic purpose. The GEPON architecture is implemented in access networks laboratory testbed. The paper includes a brief description of GEPON standardization, a description of laboratory GEPON equipment architecture and a short presentation of proposed laboratory exercises. The exemplary performance results are included.The proposition of GEPON architecture testbed...
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Design and investigations of a micro-turbine flow part
Publication-generative micro-power plant with the HFE7100 as a working medium was designed and built for experimental investigations. The heat output of the plant was assumed equal to 20 kW, while the electric output amounted to about 3kW.In the paper a multi-stage micro-turbine with partial admission of all the stages is described in detail and the results of the particular experimental investigations and numerical calculations are shown,...
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Updating a hospital building. A task for innovation design
PublicationRefurbishment of a hospital, especially located in a historical building, is a task that goes far beyond a standard framework of architectural practice. A concept of modularity in the architecture of the late nineteenth and early twentieth century was only just to happen, building system installations and technical equipment appeared as the simplest solutions. Inscribing complex functional solutions into such a space is an interesting...