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Search results for: dna vaccine
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Jurnal Gizi dan Pangan
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Riset Geologi dan Pertambangan
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Non-coding RNA Research
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Dia-noesis: A Journal of Philosophy
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Masyarakat Kebudayaan dan Politik
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Non-Coding RNA Investigation
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RNA Biology
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INTERNATIONAL JOURNAL OF MACHINE TOOLS & MANUFACTURE
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Flow cytometry analysis of DNA DSBs in telomerase positive and negative cell lines after treatment with TXT2 and TXT4
Open Research DataFlow cytometry analysis of DNA DSBs in telomerase positive (A549, H460) and negative (NHBE2594, U2OS) cell lines after treatment with equitoxic concentrations of TXT2 and TXT4. MTX and DMSO were used as positive and negative controls, respectively.
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Study of the ability of TXT-compounds to promote telomeric G4 DNA thermal stabilization using FRET melting assay
Open Research DataThe data set contains a DNA melting screen obtained from the FRET melting assay. Thermal stabilities of G-quadruplex structures were analysed in the presence and in absence of ligands. TMPyP4 and MTX were used as references. Measurements were carried out in triplicate using a LightCycler 480 thermocycler (Roche Life Science) with a filter setting of...
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Generation and Characterization of a DNA-GCN4 Oligonucleotide-Peptide Conjugate: The Impact DNA/Protein Interactions on the Sensitization of DNA
PublicationRadiotherapy, the most common therapy for the treatment of solid tumors, exerts its effects by inducing DNA damage. To fully understand the extent and nature of this damage, DNA models that mimic the in vivo situation should be utilized. In a cellular context, genomic DNA constantly interacts with proteins and these interactions could influence both the primary radical processes (triggered by ionizing radiation) and secondary reactions,...
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Human Vaccines & Immunotherapeutics
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Expert Review of Vaccines
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Widoczność na przejściach dla pieszych
PublicationPrzyczyną powstawania większości wypadków drogowych z udziałem pieszych są w Polsce błędy popełniane przez użytkowników dróg, a także błędy planistyczne i projektowe oraz bardzo często źle utrzymana infrastruktura drogowa. Jednym z istotnych czynników wpływających na wypadki z pieszymi przekraczającymi jezdnię są ograniczenia obszarów dobrej widoczności pieszych i pojazdów na przejściach dla pieszych. W Polsce ten problem jest...
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Modeling lignin extraction with ionic liquids using machine learning approach
PublicationLignin, next to cellulose, is the second most common natural biopolymer on Earth, containing a third of the organic carbon in the biosphere. For many years, lignin was perceived as waste when obtaining cellulose and hemicellulose and used as a biofuel for the production of bioenergy. However, recently, lignin has been considered a renewable raw material for the production of chemicals and materials to replace petrochemical resources....
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Selection of form factors of machine carrying systems in reliance on the process duty
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Features of Machine Cyclogram Optimization with the Account of Interaction of Mechanism Links with Stops
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Determination of the rigidity and deformation energy of the technological machine load-carrying systems
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Study of various machine learning approaches for Sentinel-2 derived bathymetry
PublicationIn recent years precise and up-to-date information regarding seabed depth has become more and more important for companies and institutions that operate on coastlines. While direct, in-situ measurements are performed regularly, they are expensive, time-consuming and impractical to be performed in short time intervals. At the same time, an ever-increasing amount of satellite imaging data becomes available. With these images, it...
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Control system based on the modified multiscalar model for the double fed machine
PublicationPrzedstawiono układ sterowania maszyną asynchroniczą dwustronnie zasilaną wykorzystujący zmodyfikowany model multisaklarny. Wprowadzone nielinowe sprzężenia pozwalają na podział systemu na dwa niezależne podukłady. Pododuje to brak zauważalnych sprzężeń przy regulacji mocy czynnej i biernej regulowanej przez kontrolery PI. W układzie wyeliminowano konieczność stosowania kaskadowego połączenia regulatorów. Przedstawiono wyniki symulacji.
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Modular machine learning system for training object detection algorithms on a supercomputer
PublicationW pracy zaprezentowano architekturę systemu służącego do tworzenia algorytmów wykorzystujących metodę AdaBoost i służących do wykrywania obiektów (np. twarzy) na obrazach. System został podzielony na wyspecjalizowane moduły w celu umożliwienia łatwej rozbudowy i efektywnego zrównoleglenia implementacji przeznaczonej dla superkomputera. Na przykład, system może być rozszerzony o nowe cechy i algorytmy ich ekstrakcji bez konieczności...
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Dangerous sound event recognition using Support Vector Machine classifiers
PublicationA method of recognizing events connected to danger based on their acoustic representation through Support Vector Machine classification is presented. The method proposed is particularly useful in an automatic surveillance system. The set of 28 parameters used in the classifier consists of dedicated parameters and MPEG-7 features. Methods for parameter calculation are presented, as well as a design of SVM model used for classification....
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Efficient sampling of high-energy states by machine learning force fields
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Stacking and rotation-based technique for machine learning classification with data reduction
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POPULATION-BASED MULTI-AGENT APPROACH TO SOLVING MACHINE LEARNING PROBLEMS
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Calculation of self and mutual inductances of the switched reluctance machine mathematical model.
PublicationA mathematical model of the switched reluctance machine (SRM) in a drive system obtained using Lagrange's energy method and a method of calculation of self and mutual inductances of the SRM are presented in the paper. The self and mutual inductances are elements of Lagrange's function in generalised coordinates and have been calculated using the finite element method (FEM). Selected calculation results for the particular machine...
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Molecular Diffusion Simulation on ARUZ – Massively-parallel FPGA-based Machine
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Research on a permanent magnet assisted synchronous reluctance machine with hybrid excitation
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Synthesis and Cholinesterase Inhibitory Activity of N-Phosphorylated /N-Tiophosphorylated Tacrine
PublicationNovel phosphorus and thiophosphorus tacrine derivatives were designed, synthesized and their biological activity and molecular modeling was investigated as a new potential anti-Alzheimer's disease (AD) agents. All new synthesized compound exhibited lower toxicity against neuroblastoma cell line (SH-SY5Y) in comparison with tacrine. Two analogues in the series, 7 and 9, demonstrated lack of cytotoxicity against hepatocellular cells...
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Real and Virtual Instruments in Machine Learning – Training and Comparison of Classification Results
PublicationThe continuous growth of the computing power of processors, as well as the fact that computational clusters can be created from combined machines, allows for increasing the complexity of algorithms that can be trained. The process, however, requires expanding the basis of the training sets. One of the main obstacles in music classification is the lack of high-quality, real-life recording database for every instrument with a variety...
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The use of tamping machine for diagnosising the longitudinal forces in rails of CWR track
PublicationW pracy przedstawiono przebieg prowadzonych od kilkunastu lat w Politechnice Gdańskiej badań nad wyznaczaniem sił podłużnych w szynach toru bezstykowego. Opisano skonstruowaną aparaturę pomiarową. Badania eksperymentalne polegały na podnoszeniu, a następnie poprzecznym nasuwaniu rusztu torowego za pomocą podbijarki. Rejestrowano przy tym wartości przemieszczeń toru oraz odkształcenia siłowników hydraulicznych. W rezultacie ostatnich...
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Tests on lateral resistance in railway track during operation of tamping machine
PublicationArtykuł prezentuje koncepcję prowadzenia badań oporów poprzecznych w trakcie procesu regulacji geometrycznej toru kolejowego za pomocą podbijarki. Jest to zatem kontynuacja badań nad zastosowaniem podbijarki torowej w diagnostyce toru bezstykowego; wcześniej zajmowano się kwestią określania sił podłużnych w szynach. Przedstawiono sposób wyznaczania oporów poprzecznych polegający na ciągłej rejestracji przemieszczenia oraz siły...
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Experimental examination and modification of chip suction system in circular sawing machine
PublicationThe article presents the results of experimental examination of the wood chip suction system in the existing sliding table saw before and after its modifi cation. The studies focused on the extraction hood of the mentioned system. The methodical experimental research of the pressure distribution inside the hood during wood chip removal for the selected rotational speed of saw blades of 3500 and 6000 min-1 with a diameter of 300...
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Model-Based Adaptive Machine Learning Approach in Concrete Mix Design
PublicationConcrete mix design is one of the most critical issues in concrete technology. This process aims to create a concrete mix which helps deliver concrete with desired features and quality. Contemporary requirements for concrete concern not only its structural properties, but also increasingly its production process and environmental friendliness, forcing concrete producers to use both chemically and technologically complex concrete...
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Quantitative Risk Assessment in Construction Disputes Based on Machine Learning Tools
PublicationA high monetary value of the construction projects is one of the reasons of frequent disputes between a general contractor (GC) and a client. A construction site is a unique, one-time, and single-product factory with many parties involved and dependent on each other. The organizational dependencies and their complexity make any fault or mistake propagate and influence the final result (delays, cost overruns). The constant will...
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Evaluation of aspiration problems in L2 English pronunciation employing machine learning
PublicationThe approach proposed in this study includes methods specifically dedicated to the detection of allophonic variation in English. This study aims to find an efficient method for automatic evaluation of aspiration in the case of Polish second-language (L2) English speakers’ pronunciation when whole words are analyzed instead of particular allophones extracted from words. Sample words including aspirated and unaspirated allophones...
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Predictions of cervical cancer identification by photonic method combined with machine learning
PublicationCervical cancer is one of the most commonly appearing cancers, which early diagnosis is of greatest importance. Unfortunately, many diagnoses are based on subjective opinions of doctors—to date, there is no general measurement method with a calibrated standard. The problem can be solved with the measurement system being a fusion of an optoelectronic sensor and machine learning algorithm to provide reliable assistance for doctors...
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Process of Medical Dataset Construction for Machine Learning-Multifield Study and Guidelines
PublicationThe acquisition of high-quality data and annotations is essential for the training of efficient machine learning algorithms, while being an expensive and time-consuming process. Although the process of data processing and training and testing of machine learning models is well studied and considered in the literature, the actual procedures of obtaining data and their annotations in collaboration with physicians are in most cases...
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TensorHive: Management of Exclusive GPU Access for Distributed Machine Learning Workloads
PublicationTensorHive is a tool for organizing work of research and engineering teams that use servers with GPUs for machine learning workloads. In a comprehensive web interface, it supports reservation of GPUs for exclusive usage, hardware monitoring, as well as configuring, executing and queuing distributed computational jobs. Focusing on easy installation and simple configuration, the tool automatically detects the available computing...
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Rotor-Flux Vector based Observer of Interior Permanent Synchronous Machine
PublicationThe sensorless control system of the interior permanent magnet machine is considered in this paper. The control system is based on classical linear controllers. In the machine, there occurs non-sinusoidal distribution of rotor flux together with the slot harmonics, which are treated as the control system disturbances. In this case, the classical observer structure in the (d-q) is unstable for the low range of rotor speed resulting...
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Simulation of influence of the air gap asymmetryon voltage waveforms of a synchronous machine
PublicationResults of simulation of a synchronous generator with the air gap asymmetry characterised by eccentricity are presented in the paper. The Lagrange's energy method has been used in derivation of the model equations. Analysis of influence of the air gap asymmetry on characteristics of self and mutual inductances of windings, as well as analysis of induced voltage waveforms as a function of the air gap asymmetry have been performed....
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Testing motional accuracy of a manufacturing machine - a task imposed on modern maintenance
PublicationArtykuł dotyczy zagadnień utrzymania ruchu maszyn w powiązaniu z problemami parametryzacji zautomatyzowanych napędów. Przedstawiono krótki przegląd i kierunki rozwoju wspomagania komputerowego w ramach zakładowych systemów utrzymania ruchu. Zwrócono uwagę na pomijanie w popularnie publikowanych graficznych modelach systemów informatycznych CIM, ich podsystemów dedykowanych dla wspomagania utrzymania ruchu maszyn, podczas gdy takie...
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Na Ratunek
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An integrated DNA and RNA variant detector identifies a highly conserved three base exon in the MAP4K5 kinase locus
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DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine
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Data regarding a new, vector-enzymatic DNA fragment amplification-expression technology for the construction of artificial, concatemeric DNA, RNA and proteins, as well as biological effects of selected polypeptides obtained using this method
PublicationApplications of bioactive peptides and polypeptides are emerging in areas such as drug development and drug delivery systems. These compounds are bioactive, biocompatible and represent a wide range of chemical properties, enabling further adjustments of obtained biomaterials. However, delivering large quantities of peptide derivatives is still challenging. Several methods have been developed for the production of concatemers –...
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DNA and its Metaphors
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Raw data of AuAg nanoalloy plasmon resonances used for machine learning method
Open Research DataRaw data used for machine learning process. UV-vis measurements of AuAg alloyed nanostructures created from thin films. Plasmonic band position dependence on fabrication parameters. Small presentation reviewing achieved structures and their properties.
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Numeryczna analiza wpływu budowy podpory mostu na rzece Wiśle na przepływ i rozmycie dna koryta rzeki
PublicationW artykule opisano wyniki hydraulicznej analizy wpływu jednego z filarów mostu w Kwidzynie na zmianę pola prędkości przepływu i warunków transportu rumowiska w rzece Wiśle, powodujących lokalne rozmywanie dna koryta rzeki w rejonie filara zlokalizowanego w nurcie rzeki. Bezpośrednią przyczyną podjęcia badań były zaobserwowane podczas budowy mostu lokalne rozmycia dna w sąsiedztwie podpory nr 24.
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Klasyfikacja dna morskiego na podstawie kątowej zależności cech echa z sonaru wielowiązkowego
PublicationPrzedstawiono metodę rozpoznawania i klasyfikacji rodzaju dna morskiego opartą na przetwarzaniu echa z sonaru wielowiązkowego. Metoda ta polega na obliczaniu zbioru parametrów obwiedni ech dla poszczególnych wiązek, podobnie jak w metodach wykorzystujących echosondy jednowiązkowe. Następnie estymowana jest zależność wartości poszczególnych parametrów od kąta wiązki oraz badane jest powiązanie otrzymanej zależności z rodzajem dna...