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Budownictwo Przemysłowe II projektowanie
e-Learning CoursesProjektowanie z BP II jest częścią przedmiotu BP II wykładanego na II semestrze studiów magisterskich specjalności BO. Na zajęciach zajmujemy się sposobem konstruowania i obliczeniami elementów konstrukcji budowlanych występujących w budownictwie przemysłowym (i nie tylko). Zagadnienia na które kładziemy nacisk to specyficzne obciążenia np. dynamiczne i specyficzne rozwiązania konstrukcyjne np. zespolenie występujące w budownictwie...
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Budownictwo Przemysłowe I projektowanie sem. VI ns.
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Dr.shazia Farheen Qureshi
PeopleI am Psychiatrist wants to heal and inspire the minds. I did post grdauation from College of Physicians and Surgeons of Bombay, Mumbai, India. I am having 10 years experience in field of Psychiatry in variety of Clinical settings that have included Child, Adolesecent, Geriatric and Forensic Psychiatry and drug deaddiction services also clinical research work.
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Drug affinity to human serum albumin prediction by retention of cetyltrimethylammonium bromide pseudostationary phase in micellar electrokinetic chromatography and chemically advanced template search descriptors
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High-Throughput Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry as an Alternative Approach to Monitoring Drug Resistance of Hepatitis B Virus
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Systemy ekspresyjne białek cytochromu P450 w badaniach in vitro metabolizmu leków = Expression systems of cytochrome P450 proteins in studies of drug metabolism in vitro
PublicationBiałka cytochromu P450 to najważniejsze enzymy biorące udział w metabolizmie większości stosowanych w klinice leków, odpowiedzialne za ich aktywację lub detoksykację. Niektóre z dróg metabolizmu leku mogą być jednak odpowiedzialne za jego podwyższoną toksyczność. Nowe systemy ekspresyjne białek cytochromu P450 w komórkach ssaków, w tym człowieka, projektowane są w celu poznania roli metabolizmu w mechanizmie działania potencjalnych,...
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The phenomenology, socio-demographic, and clinical profile of substance abusers admitted to drug de-addiction unit at eradah and mental health hospital, taif, Saudi Arabia
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Bioprocess optimization using response surface methodology for production of the anticancer drug paclitaxel by Aspergillus fumigatus and Alternaria tenuissima: Enhanced production by ultraviolet and gamma irradiation
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Białko DraD uropatogennych szczepów Escherichia coli Dr+ - mechanizm transportu na powierzchnię komórki i rola w procesie polimeryzacji struktur fimbrialnych
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DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
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Design, synthesis, and biological evaluation of tetrahydroquinolinones and tetrahydroquinolines with anticancer activity
PublicationColorectal cancer (CRC) is the most commonly diagnosed cancer in Europe and the United States and the second leading cause of cancer related mortality. A therapeutic strategy used for the treatment of CRC involves targeting the intracellular levels of reactive oxygen species (ROS). In this study, we synthesized a series of novel tetrahydroquinolinones and assessed their ability to inhibit CRC growth and proliferation by evoking...
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The Effect of Millisecond Pulsed Electric Fields (msPEF) on Intracellular Drug Transport with Negatively Charged Large Nanocarriers Made of Solid Lipid Nanoparticles (SLN): In Vitro Study
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Successive cytotoxicity control by evolutionary surface decorated electronic push-pull green ZnCr-LDH nanostructures: Drug delivery enlargement for targeted breast cancer chemotherapy
PublicationThe reason for the increasing bioavailability and biocompatibility of the porous nanomaterials in the presence of different (bio)molecules is still unknown. The role of difference functional groups and their interactions with the potential bioavailability and biocompatibility is of great importance. To investigate the potential contribution of the electronic effects (especially on the surface of the porous nanomaterials) on their...
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Development of novel (BiO)2OHCl/BiOBr enriched with boron doped-carbon nanowalls for photocatalytic cytostatic drug degradation: Assessing photocatalytic process utilization in environmental condition
PublicationIn this work, a series of novel (BiO)2OHCl/BiOBr-x%B:DGNW (x = 0%, 1%, 1.5%, 2%) composites with different content of boron-doped diamond/graphene nanowalls (B:DGNW) were fabricated by simple solvothermal synthesis. A boron-doped diamond/graphene nanowalls (B:DGNW) were prepared by CVD method. A series of analyses: XRD, XPS, SEM, and TEM showed that the photocatalyst (BiO)2OHCl/BiOBr-x%B:DGNW with a “flower-like” morphology was...
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Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
PublicationProliferation and expansion of leukemia is driven by leukemic stem cells (LSCs). Multidrug resistance (MDR) of LSCs is one of the main reasons of failure and relapses in acute myeloid leukemia (AML) treatment. In this study, we show that maintaining HL-60 at low cell culture density or applying a 240-day treatment with anthrapyridazone (BS-121) increased the percentage of primitive cells, which include LSCs determining the overall...
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Recent Patents on Endocrine Metabolic & Immune Drug Discovery
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World Research Journal of Computer-Aided Drug Design
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Javed Ather Siddiqui DR.
PeopleI AM PSYCHATRIST,WANTS TO BRING SMILE ON THE FACES OF MENTALLY ILL PATIENTS. I LOVE MY PROFESSION AND WANT TO FACE CHALLENGES FOR SAKE OF THE PATIENTS. I EARNED POST GRADUATE DEGREE FROM MUMBAI UNIVERSITY AT G S SRTH MEDICAL COLLEGE AND KEM HOSPITAL, MUMBAI, INDIA. I HAVE OVER 20 YEARS OF MENTAL HEALTH EXPERIENCE. I HAVE WORKED IN VARIETY OF CLINICAL SETTINGS THAT HAVE INCLUDED DRUG DEADDICTION, CHILD, ADOLESCENT, GERIATRIC AND...
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The new esters derivatives of betulin and betulinic acid in epidermoid squamous carcinoma treatment – In vitro studies
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Krzysztof Drąg dr inż.
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Biochemical characteristic of biofilm of uropathogenic Escherichia coli Dr+ strains.
PublicationUrinary tract infections caused by Escherichia coli are very common health problem in the developed countries. The virulence of the uropathogenic E. coli Dr+ IH11128 is determined by Dr fimbriae, which are homopolymeric structures composed of DraE subunits with the DraD protein capping the fiber. In this study, we have analyzed the structural and biochemical properties of biofilms developed by E. coli strains expressing Dr fimbriae...
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Piotr Chrostowski dr hab. inż.
PeoplePiotr Chrostowski – specjalizuje się w zagadnieniach infrastruktury transportu kolejowego. Główne kierunki działalności naukowej dotyczą właściwości mechanicznych elementów nawierzchni torowej oraz problematyki identyfikacji i oceny układów geometrycznych dróg szynowych z wykorzystaniem technik GNSS. W roku 2004 Uzyskał stopień magistra inżyniera na kierunku Budownictwo w specjalności Inżynieria Kolejowa na Wydziale Inżynierii...
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Applications of Unnatural Amino Acids in Protease Probes
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Instytut Badawczy Dróg i Mostów
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Numerical analyses of novel prefabricated structural wall panels in residential buildings based on laboratory tests in scale 1:1
PublicationThe paper presents experimental and numerical investigations on novel prefabricated composite building wall panels for residential building constructions. The wall panels were composed of reinforced concrete ribbed elements with the core from the EPS foam as the thermal insulation. The wall panels in the full-scale 1:1 were subjected to vertical loads. In the first step, the experiments were analysed with simple usual static methods....
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Fast Low-fidelity Wing Aerodynamics Model for Surrogate-Based Shape Optimization
PublicationVariable-fidelity optimization (VFO) can be efficient in terms of the computational cost when compared with traditional approaches, such as gradient-based methods with adjoint sensitivity information. In variable-fidelity methods, the directoptimization of the expensive high-fidelity model is replaced by iterative re-optimization of a physics-based surrogate model, which is constructed from a corrected low-fidelity model. The success...
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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Opinia do projektu budowlanego kanalizacji deszczowej w projektowanej ulicy Nowa Węglowa w Gdyni, przedłożonego do uzgodnienia do Zarządu Dróg i Zieleni w Gdyni
PublicationOpracowania w formie opinii do projektu budowlanego pn.: „Budowa ulicy Nowej Węglowej i tunelu pod torami kolejowymi do ul. Morskiej w Gdyni wraz z przebudową istniejącego układu komunikacyjnego - etap I budowa ulicy Nowej Węglowej w Gdyni oraz rozbudowa ul. Waszyngtona wraz z dowiązaniem do istniejącego układu komunikacyjnego”. ma określać, czy przedstawione w projekcie rozwiązania techniczne są optymalne w kontekście warunków...
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Skład zanieczyszczeń wprowadzanych do środowiska wzdłuż dróg o różnym natężeniu ruchu pojazdów mechanicznych = Composition of pollutants in the water samples collected along the highways with different traffic intensity
PublicationProwadzono monitoring poziomu stężeń wybranych zanieczyszczeń w próbkach wód opadowych, spływnych, gruntowych i rzecznych, pobieranych wzdłuż dróg o różnym natężeniu ruchu pojazdów. Zlokalizowano pięć stałych punktów pobierania próbek wzdłuż dwóch szlaków komunikacyjnych; drogi o małym natężeniu ruchu nr 501 w miejscowości Sztutowo oraz wzdłuż drogi krajowej nr A7 na odcinku Nowy Dwór Gdański - Elbląg. Próbki pobierano przez okres...
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C-1311 (Symadex), a potential anti-cancer drug, intercalates into DNA between A and G moieties. NMR-derived and MD-refined stereostructure of the d(GAGGCCTC) 2 :C-1311 complex
PublicationImidazoacridinone C-1311 (Symadex®) is an antitumor agent which has been recommended for Phase II clinical trials a few years ago. Previously, it was shown experimentally that during the initial stage of its action C-1311 forms stable intercalation complexes with DNA duplexes. Herein, a NMR-derived stereostructure of d(GAGGCCTC)2:C-1311 complex was reported. The ligand was found locating itself between A and G moieties, forming...
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Numerical investigation of the core eccentricity effect on wave propagation in embedded waveguide
PublicationThe paper presents results of theoretical and numerical investigation of guided wave propagation in two-layer bars with geometric imperfections in the form of eccentric location of steel core. Steel rod of diameter equal to 1 cm embedded in composite mortar-type cover with external diameter equal to 5 cm has been taken into consideration. Several different rods with variable size of eccentricity are analysed. Results for rods with...
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Fuel cell noise data
Open Research DataMeasurement data of Hydrogen PEM fuel cels. The voltage fluctuations were measured over single cels of stack of 10 cels.
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Selected anionic and cationic surface active agents: case study on the Kłodnica sediments
PublicationSurface active agents (surfactants) are a group of chemical compounds, which are used as ingredients of detergents, cleaning products, cosmetics and functional products. After use, wastes containing surfactants or their degradation products are discharged to wastewater treatment plants or directly into surface waters. Due to their specific properties of SAAs, compounds are able to migrate between different environmental compartments...
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Michał Grochowski dr hab. inż.
PeopleProfessor and a Head of the Department of Intelligent Control and Decision Support Systems at Gdansk University of Technology (GUT). He is also a Member of the Board of the Digital Technologies Center of GUT. He received his M.Sc. degree in Control Engineering in 2000 from the Electrical and Control Engineering Faculty at the GUT. In 2004 he received a Ph.D. degree in Automatic Control and Robotics from this...
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Advanced Oxidation Processes for Degradation of Water Pollutants—Ambivalent Impact of Carbonate Species: A Review
PublicationAdvanced oxidation processes (AOPs) hold great promise in the removal of organic contaminants. Reactive oxygen species (ROS) produced in AOPs react with target pollutants to initially form several intermediate compounds that finally undergo complete mineralization. Such observations are reported, especially for laboratory-scale experiments performed in pure water. On the other hand, while considering real contaminated wastewater...
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CURRENT DRUG TARGETS
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DRUG AND ALCOHOL DEPENDENCE
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Current Drug Delivery
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Infection and Drug Resistance
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A subset of two adherence systems, acute pro-inflammatory pap genes and invasion coding dra, fim, or sfa, increases the risk of Escherichia coli translocation to the bloodstream
PublicationAn analysis of the phylogenetic distribution and virulence genes of Escherichia coli isolates which predispose this bacteria to translocate from the urinary tract to the bloodstream is presented. One-dimensional analysis indicated that the occurrence of P fimbriae and α-hemolysin coding genes is more frequent among the E. coli which cause bacteremia. However, a two-dimensional analysis revealed that a combination of genes coding...
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Maszyny elektryczne wokół nas. Poszukiwanie dróg do nauczania na kierunku Elektrotechnika Politechniki Gdańskiej = Electrical machines around us. searching for teaching ways at electrical engineering of the Gdansk University of Technology
PublicationStreszczenie angielskie: This paper provides a summary of the didactic assumptions, goals and approach concerning the syllabus and description/modelling of electrical machines (EM) for teaching in the field of power electrical engineering at the Gdansk University of Technology. They have been used to write e-text book entitled "Electrical machines around us" that covered the lectures on electrical machines given for the second...
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The new measures of the population ageing
PublicationZestarzenie się populacji mierzy sie zwykle frakcją osób starszych. Miara ta nie uwzględnia rozkładu wieku wśród osób starszych. W pracy przedstawiane są nowe miary zestarzenia się populacji, których ideę zaczerpnięto z ekonomiki ubóstwa: absolutna luka wiekowa AG, relatywna luka wiekowa RAG, syntetyczna miara HRAG=HCR. RAG oraz syntetyczna miara P2. Te nowe miary testowo analizując proces zestarzenia się w 4 krajach europejskich...
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Badania emisji lotnych związków organicznych podczas nalewu asfaltu do autocystern oraz budowy dróg asfaltowych = Emission of volatile organic compounds from road bitumen during tank filling and road paving
PublicationOstatnio ma miejsce dyskusja poświęcona emisji lotnych związków organicznych towarzyszącej "niehermetycznemu" nalewowi asfaltów oraz budowie dróg asfaltowych. Asfalt naftowy wytwarzany jest poprzezutlenianie pozostałości z destylacji próżniowej. Zarówno na etapie destylacji próżniowej ropy naftowej, jak również w reaktorach utleniania asfaltu może dochodzić do przegrzewania wsadu na elementach grzejnych instalacji, a w wyniku zachodzi...
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Przewidywane kierunki rozwoju technologii utrzymania dróg szynowych z uwzględnieniem linii dużych prędkości. Materiały Ogólnopolskiej Konferencji Naukowo-Technicznej Nowoczesne Technologie i Systemy Usprawniające Zarządzanie w Transporcie Kolejowym.
PublicationOgraniczenie nakładów na utrzymanie przy jednoczesnym zapewnieniu wysokiej jakości drogi kolejowej wymaga minimalizowania ilości podbić realizowanych w ramach napraw interwencyjnych oraz doboru, odpowiednich do warunków Polskich Linii Kolejowych, maszyn torowych
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The effect of fishing basin construction on the behaviour of a footbrdge over the port channel
PublicationThe paper analyses possible causes of failure of the rotating footbridge over the Ustka port channel. In July, 2015, strange behaviour of this object was observed in the form of excessive vibrations of bridge platform suspension rods, with the accompanying acoustic effects. A preliminary geotechnical analysis has revealed that this destructive effect was caused by the nearby construction works, namely construction of a fishing...
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Alcoholism and Drug Addiction
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Aleksander Orłowski dr hab. inż.
PeopleDr hab. inż. Aleksander Orłowski, profesor PG w Katedrze Zarządzania Wydziału Zarządzania i Ekonomii Politechniki Gdańskiej, v-ce prezes Forum Rozwoju Aglomeracji Gdańskiej. Zawodowo zajmuje się badaniem i rozwojem koncepcji Smart Cities, współautor (2016-2017) badań gotowości do Smart City dziesięciu czołowych polskich urzędów miejskich, autor książki: Model gotowości procesowej urzędu miejskiego dojścia do Smart City (2019)....
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SURFACTANTS IN KLODNICA RIVER (KATOWICE, POLAND). PART I. LINEAR ALKYLBENZENE SULPHONATES (LAS)
PublicationSurfactants are a group of compounds with specific physico-chemical properties and therefore they are used in many spheres of human activity. Surface-active substances undergo various physico-chemical transformations, what enables their migration between different elements of the environment and may lead to its pollution. Selected anionic surfactants were determined in samples of water from the Klodnica river (25 samples) and bottom...
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Budownictwo przemysłowe sem. VI st. ćwiczenia - r.a. 2021/2022
e-Learning CoursesĆWICZENIA Z PRZEDMIOTU BUDOWNICTWO PRZEMYSŁOWE I
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Hybrid Processing by Turning and Burnishing of Machine Components
PublicationThe paper presents a method of hybrid manufacturing process of long 5 shafts and deep holes by simultaneous turning and burnishing method. The tech- 6 nological results of the research focus on the influence of the basic technological 7 parameters of this process on the surface roughness of piston rods of hydraulic 8 cylinders. Research results are presented in the graphs as well as mathematical 9 formula. Set of samples were made...