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Wyniki wyszukiwania dla: GENOME%20EVOLUTION
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Variable Order Differential Models of Bone Remodelling * *This work was supported by FCT, through IDMEC, under LAETA, projects UID/EMS/50022/2013, BoneSys, joint Polish-Portuguese project Modelling and controlling cancer evolution using fractional calculus, PERSEIDS (PTDC/EMS-SIS/0642/2014) and IF/00653/2012
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Badania empiryczne związane z ewolucją języków - wybrane zagadnienia
PublikacjaAlthough language evolution is an area in science yet to be developed, its foundations lay on empirical research. The aim of this article is to present three categories of ways to get empirical data on language evolution: observing language in laboratory, monitoring animal communication and analysing pidgins and creoles. The part of the paper about language in laboratory bases on English-language articles presenting the experiments...
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Differential and Overlapping Effects of 20,23(OH)2D3 and 1,25(OH)2D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)2D3
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Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors
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Cytokine TGFβ Gene Polymorphism in Asthma: TGF-Related SNP Analysis Enhances the Prediction of Disease Diagnosis (A Case-Control Study With Multivariable Data-Mining Model Development)
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The Impact of Contemporary Technology on Shell Structures: Material and Light Solutions
PublikacjaWith the development of technology and the materials used, shell structures have developed into more complex forms. This article is a comparison between contemporary and historical shell structures. The change is an effect of the evolution in the design process that is the result of parametric design thinking. The study aims to investigate the impact of new technologies on the architectural form of shell structures. Was there any...
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Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines
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Probiotic potential of Bacillus Isolates from Polish Bee Pollen and Bee Bread
PublikacjaThe main goal of this study was the evaluation of the probiotic potential of 10 Bacillus spp. strains isolated from 5 bee bread and 3 bee pollen samples. The antagonistic interaction with Staphylococcus aureus and Escherichia coli was a primary criterion for the preliminary selection of the isolates. Three out of ten strains—PY2.3 (isolated from pollen), BP20.15 and BB10.1 (both isolated from bee bread)—were found to be possible...
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Relative product diversification in the course of economic development: import-export analysis.
PublikacjaThis paper contributes to trade diversification literature by comparing changes in relative (i.e. assessed in comparison with world patterns) heterogeneity of import and export structures in the process of economic development. In particular, by focusing on the diversification of imports, we add a missing piece to already analysed export trends. We use highly disaggregated trade statistics (4963 product lines) for 163 countries...
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Employment and export specialization patterns versus GDP per capita performance - unifying approach
PublikacjaThis paper analyses the evolution of specialization patterns along the process of economic development. The scope of the paper is twofold: first of all, it aims at understanding if the evolution of employment specialization is reflected in the same manner in trade specialisation patterns. Secondly, it explores the link between the degree of specialization on one side and cross country GDP per capita performance on the other. We...
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Novel staphylococci nucH taxonomical marker used in identification of human-associated Staphylococcus succinus subsp. casei
PublikacjaThe aim of our study was to assess the sequencing of unique nucH gene fragment based on performed bioinformatics analysis as a novel diagnostic method for the identification of difficult to identify staphylococcal human pathogenic strains. Initially, PCR-RFLP-rrn analysis specific to the spacers between 16SrDNA and 23SrDNA followed by HhaI restriction analysis was performed. Further, sequencing of nucH and 16S rDNA genes fragments...
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An MTA-phosphorylase gene discovered in the metagenomic library derived from Antarctic top soil during screening for lipolytic active clones confers strong pink fluorescence in the presence of rhodamine B.
PublikacjaIn this work, we present the construction of a metagenomic library in Escherichiacoli using the pUC19 vector and environmental DNA directly isolated fromAntarctic topsoil and screened for lipolytic enzymes. Unexpectedly, the screeningon agar supplemented with olive oil and rhodamine B revealed one unusual pinkfluorescent clone (PINKuv) out of 85 000 clones. This clone harbored a plasmid,pPINKuv, which has an insert of 8317 bp that...
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Identyfikacja i izolacja genu kodującego zaadaptowaną do zimna β-galaktozydazę Paracoccus sp. = Identification and izolation of the gene encoding cold-active β-galactosidase from paracoccus sp.
PublikacjaZaprezentowane badania były prowadzone u eehi wyizolowania ze środo¬wiska organizmu psychrofilnego, zdolnego do hydrolizy laktozy w niskiej tempe¬raturze, oraz zidentyfikowania genu kodującego (i-galaktozydazę zaadaptowaną do zimna.Poszukiwan gen został w izolowany z psychrofilnego szczepu autarkicz¬nego Paracoccus sp. 321). Na podstawie sekwencji nukleotydowej genu kodują¬cego fS-galaktozdaze ustalono skład aminokwasów),...
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Why Are Left-Handed G-Quadruplexes Scarce?
PublikacjaG-quadruplexes (G4s) are nucleic acid structures crucial for the regulation of gene expression and genome maintenance. While they hold promise as nanodevice components, achieving desired G4 folds requires understanding the interplay between stability and structural properties, like helicity. Although right-handed G4 structures dominate the experimental data, the molecular basis for this preference over left-handed helicity is unclear....
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ABSORPCJA, METABOLIZM I ROLA BIOLOGICZNA KWASÓW NUKLEINOWYCH OBECNYCH W ŻYWNOŚCI
PublikacjaKwasy nukleinowe należą do niedocenianych składników żywności, szczególnie surowej lub nisko przetworzonej. W niniejszej publikacji skupiono się na omówieniu przemian, jakim podlegają kwasy nukleinowe w przewodzie pokarmowym człowieka, procesie absorpcji nukleotydów oraz nukleozydów z przewodu pokarmowego, a także przedstawiono podstawowe etapy ich metabolizmu w komórkach organizmu. Produkty trawienia kwasów nukleinowych stanowią...
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Lean management in higher education institutions
PublikacjaThe 22nd QMOD-ICQSS Conference 2019 Krakow, Poland, 13-15 October 2019 Leadership and Strategies for Quality, Sustainability and Innovation in the 4th Industrial Revolution
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THE EUROPEAN UNION AND JAPAN TOWARDS STRATEGIC PARTNERSHIP AGREEMENT AND ECONOMIC PARTNERSHIP AGREEMENT
PublikacjaThis study aims to reveal the evolution of EU-Japan relations towards comprehensive and fully formalized strategic partnership, the main determinants of that process, as well the importance of the political and economic alliance. In the evolution of EU-Japan relations, there were identified four stages - 1960-1990, 1991-2000, 2001-2010, 2011-2018 - which had led up to strategic partnership regulated by the framework political...
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Application of Particle Image Velocimetry method for monitoring the volume changes during silo flow on the basis of X-radiographs
PublikacjaW artykule przedstawiono wyniki badań nad zastosowaniem techniki pomiarowej PIV (Particle Image Velocimetry) do analizy zmian objętościowych zachodzących w materiale sypkim w czasie opróżniania silosu prostokątnego. Jako mateirły do analizy wykorzystano cyfrowe radiografy uzyskane z kontynualnej rejestracji z użyciem systemu tomografii promieni X. Szcególny nacisk położono na analizę zmian objętościowych zachodzącyh w kanale przepływu.
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Comparative analysis of mRNA transcripts of HT-29 cell line expressed in identical quantities for pathogenic E. coli strains UM146 and UM147 with control Escherichia coli Nissle 1917
PublikacjaAim of study was comparative analysis of mRNA transcripts of HT-29 cell line, expressed in identical quantities for the combination of pathogenic and non-pathogenic Escherichia coli strains. HT-29 confluent monolayers infection with two pathogenic E. coli strains UM146 and UM147 resulted in two sets of mRNA transcripts that were identical with RNA transcripts obtained for non-pathogenic one strain E. coli Nissle 1917. In this study...
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Bioelectronic tongue: Current status and perspectives
PublikacjaIn the course of evolution, nature has endowed humans with systems for the recognition of a wide range of tastes with a sensitivity and selectivity which are indispensable for the evaluation of edibility and flavour attributes. Inspiration by a biological sense of taste has become a basis for the design of instruments, operation principles and parameters enabling to mimic the unique properties of their biological precursors. In...
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High prevalence of carriers of variant c.1528G>C of HADHA gene causing long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD) in the population of adult Kashubians from North Poland
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Adaptacja kulturowa jako wyzwanie w zespołachmiędzynarodowych
PublikacjaWyzwania dotyczące pracy w międzykulturowym środowisku są najczęściej odnoszone do menedżerów, ze względu na powszechność ich międzynarodowych migracji oraz podejmowanie międzynarodowej współpracy z kooperantami. Rozwój globalnego rynku pracy stymuluje jednak również szeregowych pracowników do poszukiwania pracy w różnych krajach, co sprawia, że wielu z nich pracuje w międzykulturowych zespołach, gdzie doświadczają kulturowego...
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Scaled agile framework. Dealing with software process‐related challenges of a financial group with the action research approach
PublikacjaThis article reports on a domain-specific software development venture at Nordea. We explore organizational constraints, challenges, and corrective actions undertaken when scaling the agile development approach of their Core Banking Platform program. The fit and required customizations of the rather complex and rigid SAFe framework in a policy-heavy financial institution are audited against the organic growth of the program. In...
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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SacNI, an isoschizomer of BanII isolated from streptomyces achromogenes recognizes the 5′-GRGCY/C sequence
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Amplification of erbB-4 oncogene occurs less frequently than that of erbB-2 in primary human breast cancer1Published in conjunction with A Wisconsin Gathering Honoring Waclaw Szybalski on the occasion of his 75th year and 20 years of Editorship-in-Chief of Gene, 10–11 August, 1997, University of Wisconsin, Madison, WI, USA.1
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Molecular cloning and initial characterization of African green monkey (Cercopithecus aethiops) corticotropin releasing factor receptor type 1 (CRF1) from COS-7 cells
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EPAS1 resistance to miRNA-based regulation contributes to prolonged expression of HIF-2 during hypoxia in human endothelial cells
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Female Fabry disease patients and X-chromosome inactivation
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Cell cycle is disturbed in mucopolysaccharidosis type II fibroblasts, and can be improved by genistein
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Analiza wpływu błędu częstotliwości próbkowania na sygnały odbierane w systemie LTE
PublikacjaW artykule dokonano analizy wpływu błędu częstotliwości próbkowania w platformie radia programowalnego na odbierany sygnał LTE (Long Term Evolution).
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Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9
PublikacjaAt the core of the CRISPR–Cas9 genome-editing technology, the endonuclease Cas9 introduces site-specific breaks in DNA. However, precise mechanistic information to ameliorate Cas9 function is still missing. Here, multimicrosecond molecular dynamics, free energy and multiscale simulations are combined with solution NMR and DNA cleavage experiments to resolve the catalytic mechanism of target DNA cleavage. We show that the conformation...
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Podejście mechatroniczne w nadzorowaniu drgań procesów obróbkowych przy dużych prędkościach skrawania.
PublikacjaW pracy przedstawiono zmodyfikowaną metodę nadzorowania drgań narzędzie-przedmiot obrabiany za pomocą sterowania optymalno-liniowego prędkością obrotową wrzeciona. Podano opis dynamiki skrawania, niestacjonarnego modelu obliczeniowego oraz sposobu nadzorowania. Zamieszczono przykład symulacji komputerowej nadzorowania drgań w procesie frezowania szybkościowego na maszynie Deckel Maho DMU 50eVolution.
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Local Structure and Stability of SEI in Graphite and ZFO Electrodes Probed by As K-edge Absorption Spectroscopy
PublikacjaThe evolution of the solid electrolyte interphase (SEI) during the first Li uptake in advanced Li-ion electrodes is studied by X-ray absorption spectroscopy (XAS). The As atoms present in the electrolyte solution were used as a local probe for monitoring the SEI growth on different electrodes. High-quality As K-edge spectra were collected in fluorescence mode for a set of graphite and carbon-coated ZnFe2O4 electrodes. XAS measurements...
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Investigating BiMeVOx compounds as potential photoelectrochemical and electrochemical materials for renewable hydrogen production
PublikacjaIn this study, BiMeVOx compounds (where Me: Co, Mo, Ce, Zr) were synthesized and characterized as potential photoelectrochemical materials for solar water splitting, the hydrogen evolution reaction (HER), and oxygen evolution reaction (OER). The analysis confirmed the successful formation of phase BiMeVOx compounds with the desired crystal structure. Among the tested materials, BiCoVOx(800) showed the highest photocurrent density...
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Anomalous decay of quantum correlations of quantum-dot qubits
PublikacjaWe study the evolution of quantum correlations, quantified by the geometric discord, of two excitonic quantum-dot qubits under the influence of the phonon environment. We show that the decay of these correlations differs substantially from the decay of entanglement. Instead of displaying sudden-death-type behavior, the geometric discord shows a tendency to undergo transitions between different types of decay, is sensitive to nonlocal...
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RESHAPING THE GDANSK HARBOR –THE CONTINUOUS PROCESS
PublikacjaGdańsk is the harbour city with a history of more than 1000 years. For many centuries the harbour structures were evolving within the central part of the historic city centre, and – in result – a specific urban structures associated with these functions were created. But the evolution of the maritime technology as well as new needs regarding servicing the ships and cargo-handling activities effected in creation of the more modern...
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Some Artificial Intelligence Driven Algorithms For Mobile Edge Computing in Smart City
PublikacjaSmart mobile devices can share computing workload with the computer cloud that is important when artificial intelligence tools support computer systems in a smart city. This concept brings computing on the edge of the cloud, closer to citizens and it can shorten latency. Edge computing removes a crucial drawback of the smart city computing because city services are usually far away from citizens, physically. Besides, we introduced...
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Mixed, quantum-classical description of electron density transfer in the collision process
PublikacjaIn this work, we investigate an ion-atom model describing the time-dependent evolution of electron density during the collision. For a S3+- H system, numerical simulations are based on classical trajectory calculations, and the electron density behaviour is described with the time-dependent Schrödinger equation. We apply the finite difference method to obtain quantitative insights into the charge transfer dynamics, providing detailed...
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A Comprehensive Review: Applications of the Kozeny–Carman Model in Engineering with Permeability Dynamics
PublikacjaIn this review article, we investigate the dynamic nature of the Kozeny–Carman Model concerning permeability and its application in engineering contexts. Providing insights into the changing dynamics of permeability within mining, petroleum, and geotechnical engineering, among other engineering applications. While some are complex and require additional modifcations to be applicable, others are simple and still function in specifc...
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Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.
PublikacjaEnterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). Acquisition of resistance determinants not only seriously limits available therapeutic options but also increases available gene pool for other species. It is believed that the recent evolution of two clinically relevant species, Enterococcus faecalis and Enterococcus faecium occurred...
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Internationa;isation of Firms through Networks- Empirical Evidence from Poland
PublikacjaThe aim of the article is to illustrate the role of netwiorks in the internatiuonalisation process of firms. It discuusses the evolution of academic reseach on firm internationalisation through networks and explains the relationship between network and the international behaviour of firmsas well as presnting the research results.
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A new division of bacterial UvrA homologues
PublikacjaThe UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted...
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Ligation Mediated PCR methods, their possibilities and limitations
PublikacjaThe application of molecular diagnostics for bacterial strain typing or identifying bacteria at the strain level is of particular importance at present. However, among the many genotyping methods that are currently available, no single one is universally ideal. In this article, we thus review the Ligation Mediated PCR group methods as prospects from which to choose. We discuss different strategies for selecting the amplified PCR...
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New Approaches for Escherichia coli Genotyping
PublikacjaEasy-to-perform, fast, and inexpensive methods of differentiation of Escherichia coli strains beyond the species level are highly required. Herein two new, original tools for genotyping of E. coli isolates are proposed. The first of the developed method, a PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) test uses a highly variable fliC gene, encoding the H antigen as a molecular target. The designing...
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The role of epigenetics in regeneration
PublikacjaComplex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...
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The Urban Mentoring as a New Method of Participatory Urban Planning in Poland
PublikacjaTwenty-five years after the return of democracy and the beginning of basing the country's economy on neoliberal developmental paradigm, Poland adopted the regulations regarding management of urban policy, which had been wait for over a decade (accession to the EU). The National Urban Policy as well as the Act on revitalization have defined, in a modern manner, the field of cooperation between the local government, the administration...
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Consistency of Quantum Computation and the Equivalence Principle.
PublikacjaThe equivalence principle, being one of the building blocks of general relativity, seems to be crucial for analysis of quantum effects in gravity. In this paper we consider the relation between the equivalence principle and the consistency of quantum information processing in gravitational field. We propose an analysis with a looped evolution consisting of steps both in the gravitational field and in the accelerated reference frame....
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Analysis of the bulk solid flow during gravitational silo emptying using X-ray and ECT tomography
PublikacjaW pracy przedstawiono wyniki pomiarów zmian koncentracji piasku bezkohezyjnego zachodzących w prostokątnym modelu silosu opróżnianym grawitacyjnie. Pomiary wykonano z zastosowaniem kontynualnego promieniowania rentgenowskiego oraz z użyciem tomografii pojemnościowej. Badania wykonano dla zróżnicowanego zagęszczenia początkowego piasku oraz różnego stopnia szorstkości ścian. Szczególny nacisk położono na zachowanie sie materiału...
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Projecting procedure for meta-material fiber
PublikacjaWe would like to show new way of derivation evolution equation for short pulses in dielectric waveguide including one model of metamaterial waveguide. This derivation model rely on projecting to the orthogonal basis. In our case to orthogonal basis for cylindrical waveguide.