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Wyniki wyszukiwania dla: LIPIDOMICS LIPID EXTRACTION METABOLOMICS LC-MS MASS SPECTROMETRY HUMAN BREAST MILK
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Application of discriminant analysis to feature extraction.
PublikacjaPierwotnie uzyskiwane wektory cech są wysokowymiarowe. Redukcja wymiarowości jest często osiągana poprzez transformacje przestrzeni cech. Niniejsza praca prezentuje uogólnione kryterium Fishera i jego podstawowe własności, dyskutowana jest także możliwość wyprowadzania i oceny heurystycznych metod ekstrakcji cech. Przedstawiono również nowy sekwencyjny algorytm selekcji cech dyskryminacyjnych.
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Automatic feature extraction for linear systems.
PublikacjaPraca przedstawia eksperymenty pokazujące istnienie uniwersalnego ekstraktora cech dla ograniczonego obszaru w przestrzeni parametrów systemu liniowego. System liniowy pobudzony był szumem o rozkładzie normalnym na wejściu. Zastosowano ewolucyjne metody poszukiwania ekstraktora w oparciu o jakość klasyfikacji sygnałów w dziedzinie cech wydobytych przez ekstraktor.
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Exploratory analysis - extraction of dispersed information
PublikacjaWiększość analityków środowiska uważa, że ich praca kończy sie z chwilą uzyskania wiarygodnych danych o zawartości w próbce poszukiwanego analitu. Jest to jednak przestarzały punkt widzenia. W typowej próbce środowiskowej oznacza się zwykle kilkanaście lub więcej analitów. ''Ręczna'' analiza wyników uzyskanych dla zestawu takich próbek jest praktycznie niemożliwa. Ponadto w takich wielowymiarowych danych najbardziej użyteczne informacje...
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The effect of local anaesthetics on apoptosis and NETosis of human neutrophils in vitro: comparison between lidocaine and ropivacaine
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Optoelectronic investigation of nanodiamond interactions with human blood
PublikacjaWe present optoelectronic investigation of in vitro interactions of whole human blood with different nanodiamond biomarkers. Plasmo-chemical modifications of detonation nanodiamond particles gives the possibility for controlling their surface for biological applications. Optical investigations reveal the biological activity of nanodiamonds in blood dependent on its surface termination. We compare different types of nanodiamonds:...
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Determination of mercury in mosses by novel cold vapor generation atmospheric pressure glow microdischarge optical emission spectrometry after multivariate optimization
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ECG measurement in the bathtub - drl on one side of the bath mass on the other - the person is moving- men
Dane BadawczeThe measurement data shows the measurement of the ECG signal in water in the bathtub. The data includes the measurement time, the reference ECG signal from the chest, and the ECG signal measured by electrodes placed in the bathtub without contact with the human body. Using the presented data, it is possible to estimate the optimal arrangement of measuring...
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The reality of the ''Lower'' and the ''Higher'' man within the human being: towards the new type of philosophical anthropology of infrastructures of the personal human being
PublikacjaW artykule, pt. " The Reality of the "Lower" and the "Higher" Man within the Human Being: Towards the New Type of Philosophical Anthropology of Infrastructures of the Personal Human Being" ("Realność "niższego" i "wyższego" człowieka w obrębie ludzkiego bytu. Ku nowemu typowi antropologii filozoficznej infrastruktur osobowego bytu ludzkiego") usiłowałem pokazać, że realność "niższego" i "wyższego" człowieka w obrębie...
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Problem of proper decomposition and initialization of acoustic and entropy modes in a gas affected by the mass force
PublikacjaThe relations connecting perturbations specific for acoustic and entropy modes in an accelerated fluid or in a fluid affected by constant mass force, are derived. They allow to decompose the total vector of perturbations and the overall energy into acoustic and non-acoustic parts uniquely at any instant. In order to do this, three quantities are required, for example total perturbations in entropy, pressure and velocity. The evaluations...
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Nanotechnology and the human environment "Nanotechnologia a środowisko człowieka"
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Development of an orbital shaker-assisted fatty acid-based switchable solvent microextraction procedure for rapid and green extraction of amoxicillin from complex matrices: Central composite design
PublikacjaIn this study, a cheap, fast and simple orbital shaker-assisted fatty acid-based switchable solvent microextraction (OS-FASS-ME) procedure was developed for the extraction of amoxicillin (AMOX) in dairy products, pharmaceutical samples and wastewater prior to its spectrophotometric analysis. Fatty acid-based switchable solvents were investigated for extracting AMOX. The key factors of the OS-FASS-ME procedure were optimized using...
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Designing issues of the alarm system in context of functional safety and human factors
PublikacjaThis article addresses selected aspects of the alarm system and human factors that should be evaluated during the design and operation of an industrial hazardous installation. In such installations the layer of protection analysis (LOPA) methodology is often applied for simplified risk analysis based on defined accident scenarios. To reduce and control the risks the safety instrumented functions (SIFs) are identified and their...
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In‐milk inactivation of Escherichia coli O157:H7 by the environmental lytic bacteriophage ECPS‐6
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Lactose Content and Selected Quality Parameters of Sheep Milk Fermented Beverages during Storage
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Lactose-rich milk replacer modifies the proteome of bloodplasma in 2-week-old calves
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The new silica-based coated SPME fiber as universal support for the confinement of ionic liquid as an extraction medium
PublikacjaThe new silica-based SPME fiber coating is reported for the first time as universal support purposed to confinement of ionic liquid as an extraction medium. Fiber coating was prepared by the sol-gel process, using potassium silicate (K2SiO3) as a precursor and dimethylformamide (DMF) as a pore-forming medium. The concept of synthesis assumes obtaining a solid porous material on the surface of the glass rod and, being characterized...
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Decomposition of Acoustic and Entropy Modes in a Non-Isothermal Gas Affected by a Mass Force
PublikacjaDiagnostics and decomposition of atmospheric disturbances in a planar flow are considered in this work. The study examines a situation in which the stationary equilibrium temperature of a gas may depend on the vertical coordinate due to external forces. The relations connecting perturbations are analytically established. These perturbations specify acoustic and entropy modes in an arbitrary stratified gas affected by a constant...
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Accelerometer signal pre-processing influence on human activity recognition
PublikacjaA study of data pre-processing influence on accelerometer-based human activity recognition algorithms is presented. The frequency band used to filter-out the accelerometer signals and the number of accelerometers involved were considered in terms of their influence on the recognition accuracy.
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Human Feedback and Knowledge Discovery: Towards Cognitive Systems Optimization
PublikacjaCurrent computer vision systems, especially those using machine learning techniques are data-hungry and frequently only perform well when dealing with patterns they have seen before. As an alternative, cognitive systems have become a focus of attention for applications that involve complex visual scenes, and in which conditions may vary. In theory, cognitive applications uses current machine learning algorithms, such as deep learning,...
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Successive cytotoxicity control by evolutionary surface decorated electronic push-pull green ZnCr-LDH nanostructures: Drug delivery enlargement for targeted breast cancer chemotherapy
PublikacjaThe reason for the increasing bioavailability and biocompatibility of the porous nanomaterials in the presence of different (bio)molecules is still unknown. The role of difference functional groups and their interactions with the potential bioavailability and biocompatibility is of great importance. To investigate the potential contribution of the electronic effects (especially on the surface of the porous nanomaterials) on their...
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Human-Computer Interaction, sem. letni 2018/2019
Kursy Online -
Human voice modification using instantaneous complex frequency
PublikacjaThe paper presents the possibilities of changing human voice by modifying instantaneous complex frequency (ICF) of the speech signal. The proposed method provides a flexible way of altering voice without the necessity of finding fundamental frequency and formants' positions or detecting voiced and unvoiced fragments of speech. The algorithm is simple and fast. Apart from ICF it uses signal factorization into two factors: one fully...
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Measurement of plasma 25-hydroxyvitamin D2, 25-hydroxyvitamin D3 and 3-epi-25-hydroxyvitamin D3 in population of patients with cardiovascular disease by UPLC-MS/MS method
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CdWO/sub 4/ crystal in gamma-ray spectrometry
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Electron Paramagnetic Resonance Spectroscopy and Forward Recoil Spectrometry
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Determination of the uncertainty of mass flow measurement using the orifice for different values of the Reynolds number
PublikacjaStandard orifice flowmeters are widely used in the chemical and energy industry. Therefore, it is essential to know how accurate the measurements made with these instruments are. The paper presents an estimation of measurement uncertainty of a liquid mass flow using the orifice plate. The authors will present the influence of ranges of the Reynolds number on the estimated uncertainty, obtained on the basis of simulation and laboratory...
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BREAST CANCER RESEARCH AND TREATMENT
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Human capital quality indicators for measuring regional knowledge economy advances
PublikacjaBuilding Knowledge Economies (KE) is a long-term process. However, civilizational and technological changes together with EU's Lisbon Strategy help in creating solutions that may speed up economical growth of countries and their regions. This seems to be a very important issue, as during last two centuries history shown, that wisdom and human invention and innovation are the most important factor driving economical growth. In this...
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Breast Cancer-Basic and Clinical Research
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Prediction of Overall In Vitro Microsomal Stability of Drug Candidates Based on Molecular Modeling and Support Vector Machines. Case Study of Novel Arylpiperazines Derivatives
PublikacjaOther than efficacy of interaction with the molecular target, metabolic stability is the primary factor responsible for the failure or success of a compound in the drug development pipeline. The ideal drug candidate should be stable enough to reach its therapeutic site of action. Despite many recent excellent achievements in the field of computational methods supporting drug metabolism studies, a well-recognized procedure to model...
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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Human Factors and Functional Safety Analysis in Designing the Control Rooms of Industrial Hazardous Plants
PublikacjaIn this work some aspects of human factors and functional safety analysis in designing the control rooms of industrial hazardous plants are presented. The “defence in depth” (D-in-D) concept is outlined. Some designing issues of the alarm system (AS) with regard to human factors to be supported using the human reliability analysis (HRA) are discussed. The AS and decision support system (DSS), when properly designed, would contribute...
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Green tea protects against ethanol-induced lipid peroxidation in rat organs
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Extension of the UNRES Coarse-Grained Force Field to Membrane Proteins in the Lipid Bilayer
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Nanostructured Lipid Carriers Engineered as Topical Delivery of Etodolac: Optimization and Cytotoxicity Studies
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Potentiometric sensor with lipid-polymer membranes for quality assessment of French red wines
PublikacjaThe quality of wines resulting from vineyard management is important for consumers due to the taste and price of wines. In this work, the quality of red wines of three vintages has been investigated by potentiometric sensors with six all-solid-state electrodes. Two series of experiments were carried out. The first involved a qualitative analysis of wine of different vintages from freshly opened bottles. The second consisted of...
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Lipid oxidation and lysine availability in Atlantic mackerel hot smoked in mild conditions.
PublikacjaZawartość nadtlenków w wędzonych makrelach była o 50% mniejsza, a liczba anizydynowa 2,5 razy większa niż w surowych rybach. Przechowywanie ryb wędzonych w temp. +2C nie wpłynęło na zawartość produktów utlenienia lipidów. Zawartość dostępnej lizyny była podobna w surowych i wędzonych rybach. Skóra ryb wędzonych zawierała 2 razy więcej fenoli niż tkanka mięśniowa.
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Investigation of some taste substances using a set of electrodes with lipid-modified membranes.
PublikacjaSkonstruowano 5-cio kanałaowy sensor smaku oparty na elektordach jonoselektywnych z membranami polimerowymi modyfikowanymi lipidem. Badano potencjał elektrod w roztworach kwaśnych zawierających różne stężenie kwasu cytrynowego, solnego i octowego. Sensor jest czuły na stężenia substancji kwaśnych z wyjątkiem kwasu octowego. Testowano nowy typ elektrod zawierających polimer przewodzący PEDT/PSS i kwas oleinowy. Stwierdzono, że...
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Lipid oxidation and lysine availability in smoked Atlantic mackerel fillets and Baltic sprats.
PublikacjaNie wykazano korelacji między stopniem utlenienia lipidów a ich zawartością w rozmrożonych filetach makreli. Gorące i zimne wędzenie nie wływało na liczbę nadtlenkową w mięsie filetów makreli, natomiast w mięsie wędzonych szprotów była ona znacznie mniejsza niż w rybach surowych. Wędzenie nie powodowało obniżenia dostępnej lizyny, chociaż liczba anizydynowa zwiększyła się dwukrotnie w wędzonych filetach makreli i czterokrotnie...
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Application of Aqueous Biphasic Systems Extraction in Various Biomolecules Separation and Purification: Advancements Brought by Quaternary Systems
PublikacjaAqueous biphasic systems (ABS) extraction is a simple, selective, efficient and easy to scale-up technology that, over the years, has attracted a considerable attention from the researcher community as an alternative methodology in downstream processing of a wide variety of biomolecules. This review summarizes and discusses the fundamental features of ABS, as well as its advantages and disadvantages, as a separation and purification...
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Comparing the permeability of human and porcine small intestinal mucus for particle transport studies
PublikacjaThe gastrointestinal mucus layer represents the last barrier between ingested food or orally administered pharmaceuticals and the mucosal epithelium. This complex gel structure plays an important role in the process of small intestinal absorption. It provides protection against hazardous particles such as bacteria but allows the passage of nutrients and drug molecules towards the intestinal epithelium. In scientific research, mucus...
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Using human behavior to develop knowledge-based virtual organisations
PublikacjaPropozycja modelu opartego na zachowaniach ludzkich dla potrzeb budowy wirtuanych organizacji opartych na wiedzy.Virtual organizations promote dynamic interaction between individuals, groups, and organizations, who share their capabilities and resources to pursue a common goal and maximize their benefits. Among these resources, knowledge is a critical one that requires special attention in order to support problem-solving activities...
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Quality control of cheese samples for the presence of natamycin preservative – A natural deep eutectic solvent (NADES) based extraction coupled with HPLC
PublikacjaA new protocol for the determination of natamycin – an antifungal agent used as a food preservative - in cheese samples – is described. This new method is based on a natural deep eutectic solvent (NADES) green extraction procedure. High-performance liquid chromatography (HPLC) was used for detection and quantification. NADESs with different molar ratios were evaluated for efficient and selective extraction. NADES made of thymol...
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A Novel IoT-Perceptive Human Activity Recognition (HAR) Approach Using Multi-Head Convolutional Attention
PublikacjaTogether with fast advancement of the Internet of Things (IoT), smart healthcare applications and systems are equipped with increasingly more wearable sensors and mobile devices. These sensors are used not only to collect data, but also, and more importantly, to assist in daily activity tracking and analyzing of their users. Various human activity recognition (HAR) approaches are used to enhance such tracking. Most of the existing...
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Human Factors and Cognitive Engineering in Functional Safety Analysis
PublikacjaHuman factors and cognitive engineering are considered nowadays as important multidisciplinary domains that focus on improving the relations between humans, technology and systems to be supervised and operated. The industrial automation and control systems (IACS) in hazardous plants are increasingly computerized and perform various safety functions. These are usually designed and implemented according to the functional safety requirements....
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Human Capital Management by Ralf Knegtmans XI edition
Kursy Online -
Human Capital Management by Ralf Knegtmans XII edition
Kursy Online -
THIRD-ORDER EXPONENTIAL INTEGRATOR FOR LINEAR KLEIN–GORDON EQUATIONS WITH TIME AND SPACE-DEPENDANT MASS
PublikacjaAllowing for space- and time-dependance of mass in Klein–Gordon equations re- solves the problem of negative probability density and of violation of Lorenz covariance of interaction in quantum mechanics. Moreover it extends their applicability to the domain of quantum cosmology, where the variation in mass may be accompanied by high oscillations....
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THIRD-ORDER EXPONENTIAL INTEGRATOR FOR LINEAR KLEIN–GORDON EQUATIONS WITH TIME AND SPACE-DEPENDANT MASS
PublikacjaAllowing for space- and time-dependance of mass in Klein–Gordon equations re- solves the problem of negative probability density and of violation of Lorenz covariance of interaction in quantum mechanics. Moreover it extends their applicability to the domain of quantum cosmology, where the variation in mass may be accompanied by high oscillations....
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Edible dragonflies and damselflies (order Odonata) as human food – A comprehensive review
PublikacjaThe rapid growth of the human population leads to a big concern about the food y and demand worldwide. However, due to the reduction in global arable land area, humans need to find alternative food sources to fulfil their needs. Consequently, edible insects have been identified as a promising solution to ameliorate food security and increase global nutrition. Among more than 2,100 identified edible insect species, dragonflies and...