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Supplementation of garlic lowers lipids and increases antioxidant capacity in plasma of rats
PublikacjaZbadano bioaktywność surowego i gotowanego czosnku (Allium sativium L.). Stwierdzono, że gotowanie czosnku w temperaturze 100 °C przez 20 minut nie wpływa na jego bioaktywność.Samcom szczurów (z badanej populacji) podzielonym losowo na 10 grup, podawano żywność z różnym dodatkiem czosnku. Natomiast grupa kontrolna była karmiona dietą podstawową złożoną ze skrobi pszenicznej, oleju sojowego, celulozy, minerałów i mieszaniny witamin....
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Ultraviolet to near-infrared down-conversion in Bi3+–Yb3+ co-doped YAM phosphor
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The prevalence of familiar hypercholesterolemia in patients of Lodz hospital and their treatment analysis
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Reaction of 4-benzylidene-2-methyl-5-oxazolone with amines, Part 2: Influence of substituents in para-position in the phenyl ring and a substituent on amine nitrogen atom on the reaction kinetics
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Carbon nanotubes linked with pitavastatin: synthesis and characterisation
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Effect of diet on the capacity to remove mercury from the body of a penguin (Spheniscus demersus) living in the ZOO
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C90 PATHOLOGICAL CHARACTERISTICS OF UROTHELIAL CELL CARCINOMA OF THE BLADDER IN YOUNG PATIENTS
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Buffer contribution to formation enthalpy of copper(II)–bicine complex determined by isothermal titration calorimetry method
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ABC transporters Cdr1p, Cdr2p and Cdr3p of a human pathogen Candida albicans are general phospholipid translocators
PublikacjaFluoryzujące analogi fosfolipidów NBD-PE, NBD-PC i NBD-PS zostały wykorzystane w celu wykazania, że białko Cdr1p i jego inne homologi, Cdr2p i Cdr3p, należące do grupy białek zawierających tzw. kasetę wiążącą ATP (ABC), zachowują się jak ogólne przenośniki lipidów. Wyniki badań pokazują, że transportery typu ABC występujące w C. albicans są przenośnikami fosfolipidów i aktywność ta może być jedna z fizjologicznych funkcji białek.
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Conventional and solid-contact lithium-selective electrodes based on tris(N,N-dicyclohexylamide) neutral ionophore
PublikacjaKonstruowano jonoselektywne elektrody litowe (Li-ISEs) z membraną polimerową i obojętnym jonoforem tris(N,N-dicycloheksyloamidem) jako: elektrodę konwencjonalną (z wodnym roztworem elektrolitu wewnętrznego) oraz ze stałym kontaktem (polianilina jako przekaźnik jonowo-elektronowy). Charakterystyki obu elektrod (nachylenie i zakres liniowy) są porównywalne. Badana elektroda ze stałym kontaktem wykazuje dobrą stabilność w czasie....
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Electron scattering on N2O - from cross section to diffusion coefficients.
PublikacjaW pracy przedstawiono wyniki pomiarów współczynników transportu: stosunek współczynnika dyfuzji w kierunku prostopadłym do pola elektrycznego do ruchliwości, stosunek współczynnika dyfuzji podłużnej do ruchliwości oraz prędkość dryfu elektronów w funkcji zredukowanego pola elektrycznego. Współczynniki zmierzono metodą Townsenda-Huxley´a a prędkość dryfu otrzymano wykorzystując metodę Bradbury - Nielsena. Zmierzone współczynniki...
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Electron-difusion coefficiens in N2O
PublikacjaW pracy przedstawiono wyniki pomiarów stosunku współczynników dyfuzji poprzecznych i podłużnych do ruchliwości i prędkość dryfu elektronów jako funkcję zredukowanego pola elektrycznego w N2O. Współczynniki dyfuzji wyznaczono stosując metodę Towsenda-Huxleya; prędkość dryfu otrzymano używając techniki Bradbury-Nielsen. Całkowitych i częściowych przekrojów czynnych użyto do obliczenia współczynników metodą numeryczną.
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Isolation and structure of a covalent cross-link adduct between mitomycin C and DNA
PublikacjaA DNA cross-link adduct of the antitumor agent mitomycin C (MC) to DNA has been isolated and characterized; the results provide direct proof for bifunctional alkylation of DNA by MC. Exposure of MC to Micrococcus luteus DNA under reductive conditions and subsequent nuclease digestion yielded adducts formed between MC and deoxyguanosine residues. In addition to the two known monoadducts, a bisadduct was obtained. Reductive MC activation...
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Study of the influence of thermal factors on the welding process of polyethylene gas pipelines,
PublikacjaA one-dimensional calculation scheme is proposed with the help of which it is possible to determine and set the technological parameters with the accuracy to be realized in production conditions: the temperature of the heating element and the heating time, which allows maximum mechanization of the technological operations of polyethylene gas pipelines welding. The numerical value of the coefficient of temperature for polyethylene...
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Dehydration converts DsbG crystal diffraction from low to high resolution
PublikacjaDiffraction quality crystals are essential for crystallographic studies of protein structure, and the production of poorly diffracting crystals is often regarded as a dead end in the process. Here we show a dramatic improvement of poorly diffracting DsbG crystals allowing high-resolution diffraction data measurement. Before dehydration, the crystals are fragile and the diffraction pattern is streaky, extending to 10 Å resolution....
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Polymer and graphitic carbon nitride based nanohybrids for the photocatalytic degradation of pharmaceuticals in wastewater treatment – A review
PublikacjaPharmaceuticals, including antibiotics and anti-inflammatory drugs, have been frequently detected in water reservoirs, in concentrations ranging from ng/L to μg/L, owing to their wide use in treatment of human and animal disease. Their uncontrolled use results in their increased release into the environment which is harmful for humans, animals, aquatic life and aquatic system. To remove these pollutants from water bodies, various...
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Transport deficiency is the molecular basis of Candida albicans resistance to antifungal oligopeptides
Publikacja(FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05–50 mg/L range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- and tripeptide containing FMDP (F2 and F3) were transported by Ptr2p/Ptr22p peptide transporters (PTR) and FMDP-containing...
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A new cold-adapted beta-D-galactosidase from the Antarctic Arthrobacter sp. 32c - gene cloning, overexpression, purification and properties
PublikacjaThe development of a new cold-active β-D-galactosidases and microorganisms that efficiently ferment lactose is of high biotechnological interest, particularly for lactose removal in milk and dairy products at low temperatures and for cheese whey bioremediation processes with simultaneous bio-ethanol production. In this article, we present a new β-D-galactosidase as a candidate to be applied in the above mentioned biotechnological...
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Synthesis, physicochemical and theoretical studies on new rhodium and ruthenium dimers. Relationship between structure and cytotoxic activity
PublikacjaTwo dimeric compounds of the general formulae (Et3NH)2[Rh2(μ2-L)4Cl2] (1) (where L = thiophene-2-carboxylate) and [((η6-p-cymene)Ru)2(μ-Cl)3]PF6 (2) have been synthesized using a new method. The unique anionic complex 1 (space group P bca) has octahedral coordination in which the equatorial positions are occupied by the oxygen atoms of four thiophene-2-carboxylates in a paddle wheel fashion. In complex 2 (space group ), each Ru(II)...
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Higher Absorption of Vitamin C from Food than from Supplements by Breastfeeding Mothers at Early Stages of Lactation
PublikacjaThe aim of the present study was to determine the effect of vitamin C supply in the diet of lactating women on vitamin C concentra¬tions in human milk (n = 97) sampled at different stages of lactation. Vitamin C levels were measured by liquid chromatography. Dietary intake of vitamin C was determined based on 3-day food dairies kept by breastfeeding mothers. Maternal dietary intakes of vitamin C from natural sources on lactation...
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Comparison of hydrochemistry and organic compound transport in two non-glaciated high Arctic catchments with a permafrost regime (Bellsund Fjord, Spitsbergen)
PublikacjaAn increase in air temperature related to climate change results in the retreat of glaciers, the degradation of permafrost, and the expansion of glacier-free areas in the polar regions. All these processes lead to changes in the Arctic landscape. They influence the hydrochemistry of streams and rivers fed by glaciers and thawing permafrost. In this study, we examine eighty two water samples from two non-glaciated catchments with...
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Fluconazole resistant Candida auris clinical isolates have increased levels of cell wall chitin and increased susceptibility to a glucosamine-6-phosphate synthase inhibitor
PublikacjaIn 2009 Candida auris was first isolated as fungal pathogen of human disease from ear canal of a patient in Japan. In less than a decade, this pathogen has rapidly spread around the world and has now become a major health challenge that is of particular concern because many strains are resistant to multiple class of antifungal drugs. The lack of available antifungals and rapid increase of this fungal pathogen provides an incentive...
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Cavitation-based technologies for pretreatment and processing of food wastes: Major applications and mechanisms – A review
PublikacjaConversion of food wastes to valuable products is an important topic for sustainable development. Feedstock hydrolysis is a stage strongly affecting the anaerobic digestion process, and resistance of food waste towards hydrolysis causes a decrease in product yield. Such as biomethane, biohydrogen, biohythane, VFAs, and lactic acids. Moreover, mass transfer is a serious limitation of transesterification for the production of biodiesel....
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Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid
PublikacjaBackground: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...
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Emerging anticancer activity of candidal glucoseamine-6-phosphate synthase inhibitors upon nanoparticle-mediated delivery
PublikacjaNumerous glutamine analogues have been reported as irreversible inhibitors of the glucosamine-6-phosphate (GlcN-6-P) synthase in pathogenic Candida albicans in the last 3.5 decades. Among the reported inhibitors, the most effective N3-(4-methoxyfumaroyl)-L-2,3- diaminopropanoic acid (FMDP) has been extensively studied in order to develop its more active analogues. Several peptide−FMDP conjugates were tested to deliver FMDP to its...
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The effect of exogenous application of methyl jasmonate on the lipid and carbohydrate content and composition of winter triticale (Triticosecale Wittm.) grain and the severity of fungal infections in triticale plants and grain
PublikacjaKernels of winter triticale (Triticosecale Wittm. cv. Dinaro) were analyzed. In the autumn of 2015, the effect of methyl jasmonate (MJ) on the germination of triticale kernels and the development of triticale seedlings was analyzed in a laboratory before kernels were sown in experimental plots. Kernels harvested from plots in August 2016 were analyzed to determine their lipid and carbohydrate content and composition and the severity...
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Kinetics of the Organic Compounds and Ammonium Nitrogen Electrochemical Oxidation in Landfill Leachates at Boron-Doped Diamond Anodes
PublikacjaElectrochemical oxidation (EO) of organic compounds and ammonium in the complex matrix of landfill leachates (LLs) was investigated using three different boron-doped diamond electrodes produced on silicon substrate (BDD/Si)(levels of boron doping [B]/[C] = 500, 10,000, and 15,000 ppm—0.5 k; 10 k, and 15 k, respectively) during 8-h tests. The LLs were collected from an old landfill in the Pomerania region (Northern Poland) and were...
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Attenuation of Hyperglycemia in Diabetic Rats Assisted by Immobilized Probiotic in Sodium Alginate
PublikacjaDiabetes mellitus type 2 (DM2) is the most common chronic disease worldwide, characterized mainly by increased glucose concentration in the blood and affecting several organs’ functionality. The daily consumption of probiotic bacteria can help control diabetes and reduce the damage caused. Cell immobilization techniques are a powerful tool that provides physical cell protection to such probiotic bacteria against gastrointestinal...
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublikacjaBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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Short Term Monitor of Photodegradation Processes in Ranitidine Hydrochloride Observed by FTIR and ATR FTIR
PublikacjaThe effects of degradation of ranitidine hydrochloride exposed to UVB radiation (l = 310 nm) and oxygen in a weathering chamber were studied by Fourier Transform Infrared spectroscopy (FTIR) and Attenuated Total Reflectance Fourier Transform Infrared spectroscopy (ATR-FTIR). ATR-FTIR profile indicated that the degradation was spatially heterogeneous. Significant amounts of photoproducts were detected only in a directly...
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Homoclinic solutions for a class of the second order Hamiltonian systems
PublikacjaW niniejszej pracy badamy istnienie orbit homoklinicznych dlaukładu Hamiltonowskiego drugiego rzędu: q^{..} + V_{q}(t,q) = f(t), gdzie V z iloczynu kartezjańskiego R x R^{n} do R jest postaciV(t,q) = -K(t,q) + W(t,q). Zakładamy, ze V jest T-okresowe ze względuna zmienną t, K spełnia tzw. ''pinching'' warunek, W jest superliniowew nieskończoności, a norma f w L^{2} jest wystarczająco mała.Orbitę homokliniczną takiego układu znajdujemy...
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An assessment of teeth quality of the mini gang saw blade
PublikacjaIn this work, the assessment of the effect of the operating time (90 min.) of the mini gang saw blades during sawing Scotch pine (Pinus sylvestris L.) samples upon changes of the saw blade teeth sharpness (bluntness), which was defined as an effective radius of the nose ρ , has been described. The research activities have been carried out on the Nikon Ti-S optical microscope equipped with the Nikon DS-30W camera allowing high-speed...
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THE POTENTIAL OF DIFFERENT VARIETIES OF WHITE CABBAGE IN PHYTOREMEDIATION OF ZN AND CD
PublikacjaThe species belong to the botanical family Brassi- caceae are considered to be useful for phytoremediation of soil contaminated with heavy metals. Problems with use the plants recognized as hyperacumulators is that, the plants need to be harvested shortly after the plants become mature, which causes problems of disposal of obtained biomass. When these plants are dried, they easily crumble and flake off, greatly reducing the yield obtained,...
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The differential impact of a density of Polish pine wood on cutting forces with its origin region taken into consideration
PublikacjaIn the article the dependence of cutting forces in a function the density of wood with regard to the wood origin are presented. Samples used in experiment were with Scotch pine (Pinus sylvestris L.) originating from four provenances in Poland (Figure 1). Wood density was measured by two methods: stereometric method (global density) and radiometric method (local density). Stereometric method consists in measurements the volume...
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Are stabilizing osmolytes preferentially excluded from the protein surface? FTIR and MD studies
PublikacjaInteractions between osmolytes and hen egg white lysozyme in aqueous solutions were studied by means of FTIR spectroscopy and molecular dynamics. A combination of difference spectra method and chemometric analysis of spectroscopic data was used to determine the number of osmolyte molecules interacting with the protein, and the preferential interaction coefficient in presented systems. Both osmolytes – L-proline and trimethylamine-N-oxide...
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Ocena stanu technicznego głównego układu napędowego na jednostce "Kapitan Poinc" na podstawie pomiarów drgań
PublikacjaEkspertyza diagnostyczna dotycząca stanu technicznego lini transmisji mocy (linii wałów) opracowana na podstawie przeprowadzonych pomiarów drgań w 10 punktach pomiarowych, przy jednoczesnej pracy silników napędowych L i PB (wspólnej pracy linii wałów obu burt), w IV zakresach ustalonego obciążenia wyznaczanego skokiem śrub nastawnych tzn.: 20%, 40%,60% i 80%. Pomiary prędkości i przyspieszeń drgań generowanych przez węzły konstrukcyjne...
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Fracture mechanics model of cutting power versus widespread regression equations while wood sawing with circular saw blades
PublikacjaA comparison of the theoretical cutting power consumption results forecasted with the model (FM_CM model) which include work of separation (fracture toughness) in addition to plasticity and friction, and two widespread regression equations while wood sawing with circular saw blades has been described. in and cutting power consumption forecasted. In computations of the cutting power consumption during rip sawing of Scots pine wood...
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Empirical verification in industrial conditions of fracture mechanics models of cutting power prediction
PublikacjaA comparison of experimental results obtained in the industrial conditions at a sawmill located in the Baltic Natural Forest Region (PL) and theoretical cutting power consumption forecasted with the models which include work of separation (fracture toughness) in addition to plasticity and friction has been described. In computations of cutting power consumption during rip sawing of Scots pine wood (Pinus sylvestris L.) values of...
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High temperature drying of beech with content of tension wood
PublikacjaThe presented artcle is focused on comparison of tension and normal wood of beech (Fagus sylvatica L.) in a high-temperature drying process. Samples of 26 mm thickness were selected from sapwood zone with different angle of growth rings. The article evaluated properties of tension and normal wood before and after drying process. Properties which are monitored were moisture, moisture gradients, covering tests, colour changes and...
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The effect of an active force while slide diamond burnishing of wooden shafts upon process quality
PublikacjaThe quality of the surface of wooden elements that have been turned and burnished has got a crucial meaning in the whole production process flow, since the obtained effects affect the quality of the wooden surface after finishing (coating, painting). In the paper, selected results of the investigation of the effect of the burnishing process on the surface quality of the elements after turning are presented. Research experiments...
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Relationship between left ventricular global longitudinal strain, infarct size and left ventricular function in patients with acute myocardial infarction in a stem cell therapy study
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P774Transcoronary transfer of Wharton's jelly mesenchymal pluripotent stem cells in patients with chronic ischaemic heart failure shows safety and unprecedented high-grade myocardial uptake
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Ammonium removal from aqueous solution by natural zeolite, Transcarpathian mordenite, kinetics, equilibrium and column tests.
PublikacjaOpisano wyniki badań procesu usuwania jonów amonowych z wodnych roztworów modelowych z wykorzystaniem mordenitu-naturalnego zeolitu (w postaci surowej i po odpowiedniej wstępnej obróbce) zarówno w warunkach statycznych jak i dynamicznych. Oszacowano pojemność jonowymienną w stosunku do jonów amonowych (1,64 meq/g) w przypadku, gdy stężenie początkowe analitu było na poziomie 1000 mg/l. Sprawdzono również wpływ na przebieg procesu...
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AN ATTEMPT AT IDENTIFYING THE INFLUENCE OF TEST HEAD ASSEMBLY STIFFNESS ON THE RESULTS OF A TRIBOLOGICAL EXPERIMENT CONDUCTED UNDER MICRO-OSCILLATION CONDITIONS
PublikacjaThe outcome of experimental research on a group of dry bearing materials carried out under small oscillation conditi ons and using a test rig designed and made at Gdansk University of Technology inspired the decision to find out if the stiffness of test head elements in fluenced the generated results. Therefore, a computer model utilising finite elements was devised and used to simulate the workings of the test head. The mode l...
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Experimental and numerical study on polymer element used for reduction of temporary steel grandstand vibrations
PublikacjaThe purpose of the paper is to analyse the effectiveness of a polymer damper in reduction of a temporary steel grandstand vibrations through the experimental and numerical study. The damper considered in the investigation is constructed out of two L-shape steel members bonded with polymer mass of high damping properties. The element has been installed as a diagonal one at the back part of the structure. The method has been compared...
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Analysis of the structure of the atomized fuel spray with marine diesel engine injector in the early stage of injection
PublikacjaThis paper presents the results of the experimental research of the atomized fuel spray with the marine diesel engine injector in the constant volume chamber. The specificity of the phenomena occurring in the marine engine cylinder was the reason to use the optical visualisation method in the studies – the Mie scattering technique. This work presents an analysis of the influence of different geometry of outlet orifice and opening...
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Ocena stanu technicznego głównego układu napędowego na jednostce ORP Piorun na podstawie pomiarów drgań
PublikacjaEkspertyza diagnostyczna dotycząca stanu technicznego 2 linii transmisji mocy (linii wałów) opracowana na podstawie przeprowadzonych pomiarów drgań w 10 punktach pomiarowych,przy jednoczesnej pracy silników napędowych L i PB (wspólnej pracy linii wałów obu burt), w III zakresach ustalonego obciążenia: n = 750, 1000 i 1200 min-1. Razem 30 pomiarów. Pomiary prędkości i przyspieszeń drgań generowanych przez węzły konstrukcyjne okrętowego...
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Hybrid Processing by Turning and Burnishing of Machine Components
PublikacjaThe paper presents a method of hybrid manufacturing process of long 5 shafts and deep holes by simultaneous turning and burnishing method. The tech- 6 nological results of the research focus on the influence of the basic technological 7 parameters of this process on the surface roughness of piston rods of hydraulic 8 cylinders. Research results are presented in the graphs as well as mathematical 9 formula. Set of samples were made...
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Recent trends in determination of neurotoxins in aquatic environmental samples
PublikacjaAnatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate obtaining reliable results on...
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Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
PublikacjaThe antifungal activity of 5‐hydroxy‐4‐oxo‐L‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug...