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Wyniki wyszukiwania dla: BIOLOGICAL CLUSTER
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A stochastic approach for the solution of single and multi – objective optimisation problems of biological processes in sequencing batch reactor
PublikacjaThis paper investigates the impact of implementing single and multi-optimisation solutions on the biological treatment process in a sequencing batch reactor (SBR). The research is based on a case study of the water resource recovery facility (WRRF) in Swarzewo, Northern Poland. The paper introduces the adaptive extremum seeking control (ESC) method for dissolved oxygen (DO) concentration control and places it in a layered control structure....
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Biological and antibacterial properties of chitosan-based coatings with AgNPs and CuNPs obtained on oxidized Ti13Zr13Nb titanium alloy
PublikacjaDespite numerous studies, the antibacterial efficiency and cytotoxicity of chitosan-based coatings with nanometals need further studies. The purpose of this research was to determine the biological properties of chitosan coatings implemented with either silver nanoparticles (AgNPs) or copper nanoparticles (CuNPs), that were electrophoretically deposited on electrochemically oxidized Ti13Zr13Nb alloy. The SEM tests were used to...
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UNRES-GPU for Physics-Based Coarse-Grained Simulations of Protein Systems at Biological Time- and Size-Scales
PublikacjaThe dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause gastroenteritis was investigated by means of long-time (about 30 μs in the laboratory timescale) molecular dynamics simulations with the coarse-grained UNRES force field. The main motion of VLP units turned out to be the bending at the junction between the P1 subdomain (that...
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The role of slowly biodegradable organic compounds in a full-scale biological nutrient removal activated sludge systems
PublikacjaThe aim of this study was to determine the immediate effects of slowly biodegradable substrates on the denitrification capability and phosphate release/uptake interactions for a full-scale biomass process from two large wastewater treatment plants (WWTPs) located in the cities of Gdansk and Gdynia (northern Poland). Since it is hard to distinguish the slowly biodegradable substrate in a direct way, a novel procedure based on batch...
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Glutathione-mediated conjugation of anticancer drugs: an overview of reaction mechanisms and biological significance for drug detoxification and bioactivation.
PublikacjaThe effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione, which can be non-enzymatic and/or catalyzed by glutathione-dependent enzymes. Glutathione usually combines with anticancer drugs and/or their metabolites to form more polar...
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Synthesis, crystal structure and spectroscopic characterization of new anionic iridium(III) complexes and their interaction with biological targets
PublikacjaThe synthesis and characterisation of new anionic iridium(II) complexes (NH4)2[IrCl4(κ2N,N’-H2biim)]2 · 5H2O (1) and ((CH3)2NH2)[IrCl4(κ2N,N’-PyBIm)] · H2O (2) are presented in this article. Spectroscopic methods (1H, 13C and 15N NMR, FTIR, UV-Vis) were used to characterize these new complexes. Solid-state structural analysis (SC-XRD) of complexes 1 and 2 shows a slightly distorted octahedral geometry of Ir(III) ions, which is...
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Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a dimericcRGD Peptide for Targeted Imaging of αVβ3 Integrin Activity
PublikacjaCyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β3 activity (a radiolabeled version, 64Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in...
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Spray-deposited carbon-nanotube counter-electrodes for dye-sensitized solar cells
PublikacjaCarbon nanotubes due to their catalytic properties are a promising alternative to platinum counter electrodes (CE) for dye-sensitized solar cells (DSSC). In this study, counter electrodes were made from double-walled carbon nanotube (DWCNT) ink using the spray printing technique and afterwards they were thermally treated at temperatures ranging from 120 to 300 °C. Morphology and structure was studied using scanning electron microscopy...
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Spray deposited carbon nanotubes counter electrodes for dye-sensitized solar cells
PublikacjaCarbon nanotubes due to their catalytic properties are a promising alternative to platinum counter electrodes (CE) for dye-sensitized solar cells (DSSC). In this study, counter electrodes were made from double-walled carbon nanotube (DWCNT) ink using the spray printing technique and afterwards thermally treated at temperatures ranging from 120 to 300 °C. Morphology and structure was studied using scanning electron microscopy and...
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Naprężeniowe pękanie korozyjne złączy spawanych nowego stopu Al-Mg ALUSTAR
PublikacjaWykonano pomiary wytrzymałości na rozciąganie, wydłużenia, czasu do zniszczenia, przewężenia i energii zniszczenia stopu rozciąganego z małą szybkością w powietrzu i 3,5 roztworze NaCl. Oceniono podatność złączy spawanych na korozję naprężeniową oraz możliwość zastosowania stopu ALUSTAR w budowie jednostek pływających.
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Acetate-Induced Disassembly of Spherical Iron Oxide Nanoparticle Clusters into Monodispersed Core−Shell Structures upon Nanoemulsion Fusion
PublikacjaIt has been long known that the physical encapsulation of oleic acid-capped iron oxide nanoparticles (OA−IONPs) with the etyltrimethylammonium (CTA+) surfactant induces the formation of spherical iron oxide nanoparticle clusters (IONPCs). However, the behavior and functional properties of IONPCs in chemical reactions have been largely neglected and are still not well-understood. Herein, we report an unconventional ligand-exchange...
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0-step K-means for clustering Wikipedia search results
PublikacjaThis article describes an improvement for K-means algorithm and its application in the form of a system that clusters search results retrieved from Wikipedia. The proposed algorithm eliminates K-means isadvantages and allows one to create a cluster hierarchy. The main contributions of this paper include the ollowing: (1) The concept of an improved K-means algorithm and its application for hierarchical clustering....
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Recognition of hazardous acoustic events employing parallel processing on a supercomputing cluster . Rozpoznawanie niebezpiecznych zdarzeń dźwiękowych z wykorzystaniem równoległego przetwarzania na klastrze superkomputerowym
PublikacjaA method for automatic recognition of hazardous acoustic events operating on a super computing cluster is introduced. The methods employed for detecting and classifying the acoustic events are outlined. The evaluation of the recognition engine is provided: both on the training set and using real-life signals. The algorithms yield sufficient performance in practical conditions to be employed in security surveillance systems. The...
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Ecological correlates of the popularity of birds and butterflies in Internet information resources
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Pro-ecological technology of wood sawing with circular saw blades
PublikacjaW niniejszym artykule opisano możliwości materiało- i energooszczędnego przecinania piłami tarczowymi. Przedstawiono również przykłady efektów zastosowania proekologicznych technologii przecinania w przemyśle.
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Axiological Dimension of Consumption in the Context of Sustainable Development and Environmental Ethics
PublikacjaPodjęta próba odpowidzi na pytanie, w jaki sposób krytyka konsumpcjonizmu i modelowanie wzorów eko-konsumpcji odwołują się do koncepcji zrownoważonego rozwoju i etyki środowiskowej.Przedstawiona argumentacja na rzecz tezy, że holistycznie ujęty zrownoważony rozwoj oraz wyzwania na rzecz cywilizacyjnej zmiany w kierunku paradygmatu ekologizmu mogą być zrealizowane poprzez przesunięcie ontologiczne...
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Scuffing resistance of DLC-coated gears lubricated with ecological oil
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Ecological trends in machining as a key factor in sustainable production – A review
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Zinc(II) complexation by some biologically relevant pH buffers
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The idea of a geothermal power station working in national geological conditions.
PublikacjaPrzedstawiono koncepcję elektrowni geotermalnej pracującej w krajowych warunkach geologicznych. Przeprowadzono analizę obiegu Clausiusa-Rankine'a i na tej podstawie dobrano parametry obiegu na czynnik niskowrzący - izobutan. Określono główne wymiary urządzeń do realizacji technicznej takiej elektrowni. Przeprowadzono uproszczoną analizę ekonomiczną takiej inwestycji.
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A design concept of fire protection system for an ecological floating dock
PublikacjaW artykule przedstawiono możliwe do wystąpienia na doku pływającym zagrożenie pożarowe oraz projekt koncepcyjny systemu zabezpieczenia przeciwpożarowego. Projekt ten obejmuje: istalację gaśniczą wodno-hydrantową i pianową do ochrony pokładu głównego oraz instalację CO2 do ochrony siłowni, rozdzielni elektrycznej i tunelu kablowego, a także instalację wykrywania i sygnalizacji pożaru.
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Sources of inspiration in designing ecological buildings. If not Pinterest than what?
PublikacjaEfficiency of ecological measures for sustainable architecture depends greatly upon the moment in which it is defined as essential, and how early it can be applied during the design concept stage. The following article refers to inspiration, the initial stage of the design and means to combine it with substantial knowledge regarding ecological architecture. Means, such as computer programs...
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Modeling of cutter displacements during ball end milling of inclined surfaces
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Machined Surface Roughness Including Cutter Displacements in Milling of Hardened Teel
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Closer Look at the Uncertainty Estimation in Semantic Segmentation under Distributional Shift
PublikacjaWhile recent computer vision algorithms achieve impressive performance on many benchmarks, they lack robustness - presented with an image from a different distribution, (e.g. weather or lighting conditions not considered during training), they may produce an erroneous prediction. Therefore, it is desired that such a model will be able to reliably predict its confidence measure. In this work, uncertainty estimation for the task...
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Physico-Chemical Characterization and Biological Tests of Collagen/Silk Fibroin/Chitosan Scaffolds Cross-Linked by Dialdehyde Starch
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Biological Control Potential of Native Entomopathogenic Nematodes (Steinernematidae and Heterorhabditidae) against Mamestra brassicae L. (Lepidoptera: Noctuidae)
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In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest
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Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples
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Comparison of two model concepts for simulation of nitrogen removal at a full-scale biological nutrient removal pilot plant
PublikacjaCelem badań było porównanie zdolności predykcyjnych dwóch mechanistycznych modeli procesu osadu czynnego (ASM1 i ASM3). W tym celu wykorzystano bazę danych empirycznych z pilotowej oczyszczalni ścieków Gummerwald w Hanowerze (Niemcy). Oba badane modele prognozowały szczytowe stężenia azotu amonowego na poziomie >8 gN/m3 w ciągu, którego obciążenie hydrauliczne wzrastało czterokrotnie w porównaniu do okresu bezdeszczowego. Prognozowany...
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Penetrating Biological Tissue Using Light-Emitting Diodes with a Highly Efficient Near-Infrared ScBO3:Cr3+ Phosphor
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Design, synthesis and biological evaluation of betulin-3-yl 2-amino-2-deoxy-β-d-glycopyranosides
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Methods and means of measuring control and diagnostics of biological tissues in vivo based on measurements of color coordinates and multispectral image
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Application of ion chromatography with pulsed amperometric detection for the determination of trace cyanide in biological samples, including breast milk
PublikacjaCyanide (CN) is the biomarker of exposure to the components of tobacco smoke, although its presence in biological samples is also due to the consumption of products containing cyanogenic glycosides. In this work, we determine the concentration of the free cyanide in urine, saliva and breast milk matrices, using ion chromatography with pulsed amperometric detection (IC-PAD). IC-PAD is an emerging method, with only few documented...
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Computer-aided analysis of signals from a low-coherence Fabry-Perot interferometer used for measurements of biological samples
PublikacjaThe aim of the study was to develop an automated computer-aided system for analysis of spectrograms obtained from measurements of biological samples performed with a low-coherence Fabry-Pérot interferometer. Information necessary to determine dispersion characteristics of measured materials can be calculated from the positions of the maxima and minima that are present in their spectra. The main challenge faced during the development...
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Chromatographic analyses of Lavandula angustifolia and Rosmarinus officinalis extracts and their biological effects in mammalian cells and cell-free systems
PublikacjaKnowledge of biological properties of natural compounds allows to understand their therapeutic value, efficacy and security. We investigated: composition of Lavandula angustifolia (LA) and Rosmarinus officinalis (RO) extracts, their antioxidant capacity, cytotoxicity and genotoxicity, their DNA-protective potential against DNA damage induced in hamster V79 cells by several genotoxins or in plasmid DNA by Fe2+ ions and activity...
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Strategies for achieving energy neutrality in biological nutrient removal systems - a case study of the Slupsk WWTP (northern Poland)
PublikacjaThe paper presents a model-based evaluation of technological upgrades on the energy and cost balance in a large biological nutrient removal wastewater treatment plant (WWTP) in the city of Slupsk (northern Poland). The proposed upgrades include chemically enhanced primary sludge removal and reduction of the nitrogen load in the deammonification process employed for reject water treatment. Simulations enabled to estimate the increased...
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Structure, Physicochemical and Biological Properties of an Aqua (2,2′,2′′-Nitrilotriacetato)-oxidovanadium(IV) Salt with 4-Methylpyridinium Cation
PublikacjaThe crystal structure of a nitrilotriacetate (nta) oxidovanadi-um(IV) salt with 4-methylpyridinium cation, [4-Me(Py)H]+, of [4-Me(Py)H][VO(nta)(H2O)] stoichiometry was determined. The com-plex comprises a discrete mononuclear [VO(nta)(H2O)]–coordinationentity that can be rarely found among other known compounds con-taining nitrilotriacetate oxidovanadium(IV) moieties. The complex wascharacterized by spectroscopic (IR and EPR) methods,...
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Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) is responsible for the hydrolysis of biologically inactive sulfated steroids into their active un-sulfated forms and promotes the growth of various hormone-dependent cancers (e.g., breast cancer). Therefore, the STS enzyme is a promising therapeutic target for the treatment of steroid-sensitive cancers. Herein, we report the synthesis and biological evaluation of sulfamate analogs as potential STS inhibitors...
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Advantages and limitations of classic and 3D QSAR approaches in nano-QSAR studies based on biological activity of fullerene derivatives
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Strategies for Achieving Energy Neutrality in Biological Nutrient Removal Systems – a Case Study of the Slupsk WWTP (northern Poland)
PublikacjaThe paper presents a model-based evaluation of technological upgrades on the energy and cost balance in a large biological nutrient removal wastewater treatment plant (WWTP) in the city of Slupsk (northern Poland). The proposed upgrades include chemically enhanced primary sludge removal and reduction of the nitrogen load in the deammonification process employed for reject water treatment. Simulations enabled to estimate the increased...
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A Comprehensive Review on the Medicinal Importance; Biological and Therapeutic Efficacy of Lagenaria siceraria (Mol.) (Bottle Gourd) Standley Fruit
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An approach to adaptive beamforming in measurement of EEG.Proceedings 2nd European Medical and Biological Engineering Conference.EMBEC´02.Pt.2
PublikacjaPotencjały wywołane są wykorzystywane w diagnostyce narządów zmysłu. Ze względu na niski SNR wymagana jest wielokrotne powtarzanie stymulacji i uśrednianie wyników. Prowadzi to do zwielokrotnienia czasu badania. SNR może zostać poprawiony przy użyciu matrycy sensorów. Są one wykorzystane do śledzenia źródeł sygnału. W publikacji przedstawiono dwie metody adaptacyjnego poprawania współczynnika SNR.
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Thin layer headspace gas chromatography for biological monitoring of persons exposed to volatile organohalogen compounds from water
PublikacjaCelem pracy było zbadanie możliwości wykorzystania analizy fazy nadpowierzchniowej nad cienką warstwą cieczy z samoczynną generacją ciekłego sorbentu (TLHS)do izolacji i wzbogacania THM w próbkach moczu i krwi ludzkiej. Umożliwiło to następnie wykorzystanie prostej techniki bezpośredniego nastrzyku próbki do kolumny chromatografu gazowego, wyposażonego w detektor wychwytu elektronów (DAI-GC-ECD).Przy pomocy tak opracowanej metody...
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Improving SBR Performance Alongside with Cost Reduction through Optimizing Biological Processes and Dissolved Oxygen Concentration Trajectory
PublikacjaAuthors of this paper take under investigation the optimization of biological processes during the wastewater treatment in sequencing batch reactor (SBR) plant. A designed optimizing supervisory controller generates the dissolved oxygen (DO) trajectory for the lower level parts of the hierarchical control system. Proper adjustment of this element has an essential impact on the efficiency of the wastewater treatment process as well...
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Chemical and biological evaluation of antioxidant activity of endogenous redox-active compounds compared to plant-derived exogenous antioxidants
PublikacjaThe research conducted so far has shown that endogenous antioxidants, despite being regarded as the first line of antioxidant defense, may not be sufficient to maintain redox homeostasis in cells exposed to oxidative stress. The results obtained in the doctoral dissertation show that endogenous redox-active compounds were moderate or weak scavengers of ABTS and DPPH radicals, while in cellular setting, their impact on the reducing...
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Interactions between polyphenolic antioxidants quercetin and naringenin dictate the distinctive redox-related chemical and biological behaviour of their mixtures
PublikacjaFood synergy concept is suggested to explain observations that isolated antioxidants are less bioactive than real foods containing them. However, mechanisms behind this discrepancy were hardly studied. Here, we demonstrate the profound impact of interactions between two common food flavonoids (individual: aglycones quercetin—Q and naringenin—N− or their glycosides rutin—R and naringin—N+ vs. mixed: QN− and RN+) on their electrochemical...
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Chiral Pyrazolo[4,3-e][1,2,4]triazine Sulfonamides—Their Biological Activity, Lipophilicity, Protein Affinity, and Metabolic Transformations
PublikacjaReferring to our previous laboratory results related to the tyrosinase and urease inhibition by pyrazolo[4,3-e][1,2,4]triazine sulfonamides, we examined here in silico the mechanism of action at the molecular level of the investigated pyrazolotriazine sulfonamides by the molecular docking method. The studied compounds being evaluated for their cytotoxic effect against cancer cell lines (MCF-7, K-562) and for recombinant Abl and...
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Selected biologic markers of inflammation and activity of Crohn’s disease
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2D Viscous Flutter Analysis of a 11th Standard Configuration Using Ansys Cfx 14
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