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Novel psychopathological picture during the COVID-19 pandemic based on a first episode of psychotic depression.
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Fragmental Method KowWIN as the Powerful Tool for Prediction of Chromatographic Behavior of Novel Bioactive Urea Derivatives
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Seeking genetic signature of radiosensitivity - a novel method for data analysis in case of small sample sizes
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Synthesis and biological activity of novel mycophenolic acid conjugates containing nitro-acridine/acridone derivatives
PublikacjaOpracowano warunki reakcji kwasu mykofenolowego z aminowymi pochodnymi akrydyn i akrydonów. Tak otrzymane koniugaty zostały scharakteryzowane, a następnie przebadane in vitro pod względem aktywności przeciwbiałaczkowej oraz immunosupresyjnej.
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A Novel Ru(II) Polypyridine Black Dye Investigated by Resonance Raman Spectroscopy and TDDFT Calculations
PublikacjaThe optical properties of a new(bipyridine)2Ru(4H-imidazole) complex presenting a remarkablebroad absorption in the visible range are investigated. Thestrong overlap of the absorption with the solar radiationspectrum renders the studied complex promising as a blackabsorber and hence as a starting structure for applications inthe field of dye-sensitized solar cells. The correlations betweenstructural and electronic features for...
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An integrated hydraulic drive system of a novel device for launching lifeboats from large passenger ship
PublikacjaArtykuł przedstawia zintegrowany układ napędu i sterowania hydraulicznego systemu ewakuacyjnego składającego się z wyciągu łańcuchowego z zamocowanymi na nim łodziami ratunkowymi oraz furto-rampy rufowej. Zastosowana tu furto-rampa z elementem wypornościowym umożliwia zwiększenie jej funkcji do samoczynnego dostosowania kąta jej wychylenia roboczego w przypadku znacznego przegłębienia statku na dziób. Przedstawiony układ hydrauliczny...
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Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α1-adrenoceptor antagonistic properties
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A novel method for archiving multibeam sonar data with emphasis on efficient record size reduction and storage
PublikacjaOver the past few years considerable advances in sonar technology, spatial positioning capabilities and computer processing power have lead to significant improvements in mapping, imaging and technologies of seafloor exploration. Recently, modern multibeam echosounder systems (MBES) capable of recording backscatter data for the whole water column, not just for the seabed, have become available thus providing data allowing for...
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Molecular modeling and evaluation of novel dibenzopyrrole derivatives as telomerase inhibitors and potential drug for cancer therapy
PublikacjaDuring previous years, many studies on synthesis, as well as on anti-tumor, anti-inflammatory and anti-bacterial activities of the pyrazole derivatives have been described. Certain pyrazole derivatives exhibit important pharmacological activities and have proved to be useful template in drug research. Considering importance of pyrazole template, in current work the series of novel inhibitors were designed by replacing central...
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Impact response of novel layered two stage fibrous composite slabs with different support type
PublikacjaThe performance of novel Layered Two Stage Fibrous Composite slabs (LTSFC) was pioneered under falling mass collisions using a combined experimental and numerical study. Such LTSFC slabs consist of three layers with and without the insertion of glass fibre mesh between the layers. LTSFC techniques were used to fabricate the composite slabs with three layers including 3%, 1.5%, and 3% of fibre content for the top, middle, and...
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Impact performance of novel multi-layered prepacked aggregate fibrous composites under compression and bending
PublikacjaMulti-layered Prepacked aggregate fibrous composite (MLPAFC) is a new type of concrete, which is prepared in two subsequent stages of aggregate-fibre skeleton prepacking and cementitious grouting. In this study, ten MLPAFC mixtures were prepared in three subsequent layers incorporating different contents of four different types of steel fibres. Long and short hooked-end and crimped steel fibers were adopted with 3.0 and 1.5% dosages...
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Novel Biodegradable Potato Starch-based Compositions as Candidates in Packaging Industry, Safe for Marine Environment
PublikacjaAbout 70 % of our planet’s surface is covered by seas and oceans to which even 10 million tons of waste go every year. It makes these places the largest global landfills, containing up to 90 % of plastic waste. In this article we present the results of research on novel starch-based compositions expected to be more safe for the marine environment. For these purpose biopolymers such as, thermoplastic starch (TPS), polylactide (PLA)...
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Novel analytical method for detection of orange juice adulteration based on ultra-fast gas chromatography
PublikacjaThe food authenticity assessment is an increasingly important issue in food quality and safety. The application of an electronic nose based on ultra-fast gas chromatography technique enables rapid analysis of the volatile compounds from food samples. Due to the fact that this technique provides chemical profiling of natural products, it can be a powerful tool for authentication in combination with chemometrics. In this article,...
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A novel approach to energy safety improvement in the marine power plants with active power surge compensator
PublikacjaPaper raises a point of power surges and theirs adverse effects in the marine power plants. The article explains a source of surges appearance, and presents measurements carried out on a modern ship. It discusses effects of dynamic power transients on the ship’s energy safety. Finally it proposes, a novel approach for power surge elimination, based on medium voltage active conditioner. As well as it propose the topology and control...
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Novel luminescent calixarene-based lanthanide materials: From synthesis and characterization to the selective detection of Fe3+
PublikacjaCalix[n]arene-based coordination networks are an emerging class of materials with intriguing properties resulted from the presence of the cavity-like structure of the macrocycle and metallic nodes. In this work, four novel luminescent materials based on calix[4]arene-carboxylate and lanthanides (Eu3þ and Tb3þ) were prepared by two synthetic approaches, solvothermal (CDA-Eu-ST) and slow diffusion (CDA-Eu-RT, CDA-Tb-RT, CTA-Tb-complex)...
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A novel approach exploiting properties of convolutional neural networks for vessel movement anomaly detection and classification
PublikacjaThe article concerns the automation of vessel movement anomaly detection for maritime and coastal traffic safety services. Deep Learning techniques, specifically Convolutional Neural Networks (CNNs), were used to solve this problem. Three variants of the datasets, containing samples of vessel traffic routes in relation to the prohibited area in the form of a grayscale image, were generated. 1458 convolutional neural networks with...
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Simulation of fluid structure interaction in a novel design of high pressure axial piston hydraulic pump
PublikacjaA novel type of an axial, piston-driven high pressure hydraulic pump with variable capacity marks a significant improvement in the area of the hydraulic machinery design. Total discharge from hydrostatic forces eliminates a need for a servomechanism, thus simplifying operation, reducing weight and introducing the possibility of the pump displacement control by computer. PWK-type pumps, invented in the Gdansk University of Technology,...
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Defining a novel domain that provides an essential contribution to site-specific interaction of Rep protein with DNA
PublikacjaAn essential feature of replication initiation proteins is their ability to bind to DNA. In this work, we describe a new domain that contributes to a replication initiator sequence-specific interaction with DNA. Applying biochemical assays and structure prediction methods coupled with DNA–protein crosslinking, mass spectrometry, and construction and analysis of mutant proteins, we identified that the replication initiator of the...
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Novel Interpolation Method of Multi-DFT-Bins for Frequency Estimation of Signal with Parameter Step Change
PublikacjaThe IpDFT(Interpolation Discrete Fourier Trans-form) method is one of the most commonly used non-parametric methods. However, when a parameter (frequency, amplitude or phase) step changes in the DFT period, the DFT coefficients will be distorted seriously, resulting in the large estimation error of the IpDFT method. Hence, it is a key challenge to find an IpDFT method, which not only can eliminate the effect of the step-changed...
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A novel method of creating thermoplastic chitosan blends to produce cell scaffolds by FDM additive manufacturing
PublikacjaDue to its remarkable and promising biological and structural properties, chitosan has been widely studied in several potential applications in the biomedical sector. Attempts are being made to use this polymer and its properties in thermoplastics dedicated to 3D printing in FDM technology. However, chitosan can be processed only from acid solution, which limits its applications. The paper presents a new path for the production...
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Green energy extraction for sustainable development: A novel MPPT technique for hybrid PV-TEG system
PublikacjaThe Photovoltaic (PV) module converts only a small portion of irradiance into electrical energy. Most of the solar energy is wasted as heat, resulting in a rise in PV cell temperature and a decrease in solar cell efficiency. One way to harvest this freely available solar thermal energy and improve PV cell efficiency is by integrating PV systems with thermoelectric generators (TEG). This cogeneration approach of the hybrid PV-TEG...
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A Novel Method for Intelligibility Assessment of Nonlinearly Processed Speech in Spaces Characterized by Long Reverberation Times
PublikacjaObjective assessment of speech intelligibility is a complex task that requires taking into account a number of factors such as different perception of each speech sub-bands by the human hearing sense or different physical properties of each frequency band of a speech signal. Currently, the state-of-the-art method used for assessing the quality of speech transmission is the speech transmission index (STI). It is a standardized way...
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Studies on novel BiyXz-TiO2/SrTiO3 composites: Surface properties and visible light-driven photoactivity
PublikacjaA series of novel BiyXz-TiO2/SrTiO3 composites were prepared by multistep synthesis route. The asprepared photocatalysts were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), diffuse reflectance spectroscopy (DRS), Fourier transform infrared (FT-IR), Raman spectra and BET analysis. The photocatalytic activity test was performed in aqueous solution of phenol under...
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Numerical modeling and experimental validation of full-scale segment to support design of novel GFRP footbridge
PublikacjaThe paper contains analysis of full-scaled three meters long segment of a novel composite footbridge. Both numerical modeling and experimental validation were performed. Analyzed object is a shell type sandwich channel-like structure made of composite sandwich with GFRP laminates as a skin and PET foam as a core. Several static load schemes were performed including vertical and horizontal forces. In FEM analysis multilayered laminate...
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Novel Tools as New Challenges to HRM Communicational Practices (and the Increasingly Important Social Role of the Manager)
PublikacjaEach communicational process consists inseparably of three aspects: the linguistic (which means the whole language content of the message), technical (which states the form of the message) and the social (meaning social relations, emotions, behaviours). The recent COVID-19 pandemic deeply influenced several layers of our lives. But the main aim of this chapter is to focus on the communicational processes that normally take place...
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From tryptophan to novel mitochondria-disruptive agent, synthesis and biological evaluation of 1,2,3,6-tetrasubstituted carbazoles
PublikacjaMitochondrial targeting plays an important role in anticancer therapy. The Mn(III)-promoted cyclization of 5- (1H-indol-3-yl)-3-oxopentanoic acid allow to obtain novel substituted carbazole derivatives that can act as mitochondria-disruptive agents. The starting materials used for the synthesis of these new aminocarbazoles are oxopentanoate derivatives of tryptophan. The scope and limitation of this method of synthesis are determined...
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Novel markers of human ovarian granulosa cell differentiation toward osteoblast lineage: A microarray approach
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Dispersing hydrophilic nanoparticles in hydrophobic polymers: HDPE/ZnO nanocomposites by a novel template-based approach
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Degradable poly(ester-ether) urethanes of improved surface calcium deposition developed as novel biomaterials
PublikacjaBones, which are considered as hard tissues, work as scaffold for human body. They provide physical support for muscles and protect intestinal organs. Percentage of hard tissues in human body depends on age, weight, and gender. Human skeleton consists of 206 connected bones. Therefore, it is natural that the hard-tissue damage such as fractures, osteoporosis, and congenital lack of bone may appear. The innovative way of bone healing...
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Angiotensin receptor - neprilysin inhibiton (ARNI) – A novel therapeutic concept for management of hypertension and heart failure
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Microstructural and Mechanical Properties of Novel Co-Free Maraging Steel M789 Prepared by Additive Manufacturing
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Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng
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Linalool as a novel natural factor enhancing ginsenoside production in hairy root cultures of American ginseng
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Effect of Sieve Drum Inclination Angle on Wheat Grain Cleaning in a Novel Rotary Cleaning Device
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Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis
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Study on Technological Effects of a Precise Grooving of AlSi13MgCuNi Alloy with a Novel WCCo/PCD (DDCC) Inserts
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A concept of drive and control system of a novel device for people evacuating from large passenger ships
PublikacjaRosnąca z roku na rok liczba oraz wielkość i szybkość pasażerskich statków morskich wymusza szukanie nowatorskich lub doskonalenie dotychczasowych metod bezpiecznej ewakuacji ludzi z tak dużych obiektów. W artykule zaprezentowano koncepcję jednej z takich oryginalnych metod, w której między innymi, zastosowano wyciągi łańcuchowe do utrzymywania na czas rejsu oraz do opuszczania w razie ewakuacji łodzi ratunkowych. Przedstawiono...
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A novel hybrid composites based on biopolyamide 10.10 with basalt/aramid fibers: Mechanical and thermal investigation
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<title>Novel matrix for fiber optic chemical sensors made of particle track polymer</title>
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A novel green one-step synthesis of gold nanoparticles using crocin and their anti-cancer activities
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Structure and thermoelectric properties of Bi–Te alloys obtained by novel method of oxide substrates reduction
PublikacjaA novel method of thermoelectric materials fabrication has been developed. Oxide reagents have been melted at high temperature in air, quenched, milled to powder and reduced in hydrogen to form Bi–Te alloys. Structural and thermoelectric properties of samples have been investigated depending on initial composition and temperature of reduction process. Sample 25Bi2O3–75TeO2 reduced at 340 °C for 10 h has been found to be a p-type...
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Synthesis, Molecular Structure, Metabolic Stability and QSAR Studies of a Novel Series of Anticancer N-Acylbenzenesulfonamides
PublikacjaA series of novel N-acyl-4-chloro-5-methyl-2-(R1-methylthio)benzenesulfonamides 18–47 have been synthesized by the reaction of N-[4-chloro-5-methyl-2-(R1-methylthio) benzenesulfonyl]cyanamide potassium salts with appropriate carboxylic acids. Some of them showed anticancer activity toward the human cancer cell lines MCF-7, HCT-116 and HeLa, with the growth percentages (GPs) in the range from 7% to 46%. Quantitative structure-activity relationship...
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A Novel Coupling Matrix Synthesis Technique for Generalized Chebyshev Filters With Resonant Source–Load Connection
PublikacjaThis paper reports a novel synthesis method for microwave bandpass filters with resonant source–load connection. In effect, a network realizing N+1 transmission zeros (where N is the number of reflection zeros) is obtained. The method is based on a prototype transversal coupling matrix (N+2, N+2) with source and load connected by a resonant circuit formed by a capacitor in parallel with a frequency-invariant susceptance. To complement...
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A novel method of local chirp-rate estimation of LFM chirp signals in the time-frequency domain
PublikacjaIn the paper, novel dynamic representations of a complex signal in the time-frequency domain are introduced. The proposed approach is based on using the gradient of the short-time Fourier transform complex phase. A channelized instantaneous complex frequency (CICF) and a complex local group delay (CLGD) are included in the presented signal representations. An application of the newly-introduced distributions is demonstrated by...
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Cubane Like Structure of a Silanethiol Primary Amine Assembly a Novel, Unusual Hydrogen Bond Pattern.
PublikacjaMetodą rentgenowskiej analizy strukturalnej wyznaczono struktury krystaliczne i cząsteczkowe trzech soli amoniowych: (t-BuO)3SiS(-)H3N(+)Bu-t, (i-PrO)3SiS(-)H3N(+)Bu-t i (t-BuO)3SiS(-)H3N(+)(CH2)2CH(CH3)2. Wszystkie trzy związki w ciele stałym tworzą tetramery w których atomy S i N wyznaczają w przybliżeniu naroża sześcianu. Trwałość tych agregatów, oprócz sił elektrostatycznego przyciągania, zapewnia sieć wiązań wodorowych N-H
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Novel thermostable ssDNA-binding proteins from Thermus thermophilus and T. aquaticus-expression and purification
PublikacjaSklonowano w system ekspresyjny pET-30LIC Escherichia coli gen kodujący białka SSB-podobne Thermus thermophilus i T. aquaticus. Oczyszczono do homogenności białka SSB-podobne, a uzyskane preparaty umożliwiają wykonanie badań strukturalnych w/w białek.
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Novel thermostable ssDNA-binding proteins from Thermus thermophilus and T. aquaticus - expression and purification
PublikacjaBiałka SSB są niezbędne do życia każdemu organizmowi. W tej pracy prezentujemy wyniki otrzymania i oczyszczania białek SSB Thermus thermophilus i T. aquaticus. Dotąd były znane białka SSB jedynie o budowie homotetrameru lub heterotrimeru. Białka SSB Thermus thermophilus i T. aquaticus stanowią nową klasę białek SSB - białek homodimerycznych. Ponadto dowiedziono, iż białka te są użyteczne w reakcji PCR.
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Glutamine analogues containing a keto function - novel inhibitors of fungal glucosamine-6-phosphate synthase
PublikacjaW publikacji przedstawiono syntezę nowych pochodnych kwasu (S)-2,3-diaminopropanowego, zawierających reszty kwasów z funkcją ketonową. Dla otrzymanych związków zbadano właściwości inhibicyjne w stosunku do grzybowej syntazy glukozamino-6-fosforanu, ustalono właściwości lipofilowe otrzymanych związków a także aktywność przeciwgrzybową. Dla kilku wybranych pochodnych otrzymano ich dipeptydy, zbadano także ich aktywność przeciwgrzybową...
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Novel PCSE-based approach of inclined structures geometry analysis on the example of the Leaning Tower of Pisa
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Addition of novel benzylmagnesium “ate” complexes of BnR2MgLi type to 2-(thio)pyridones and related compounds
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