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Mechanism-based inactivation of human cytochrome P450 1A2 and 3A4 isoenzymes by antitumor triazoloacridinone C-1305.
Publikacja5-Dimethylaminopropylamino-8-hydroxytriazoloacridinone, C-1305, is a promising antitumor therapeutic agent with high activity against several experimental tumors. It was determined to be a potent and selective inhibitor of liver microsomal and human recombinant cytochrome P450 (CYP) 1A2 and 3A4 isoenzymes. Therefore, C-1305 might modulate the effectiveness of other drugs used in multidrug therapy. The objective of this study was...
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Electrophoretic deposition (EPD) of nanohydroxyapatite - nanosilver coatings on Ti13Zr13Nb alloy
PublikacjaTitanium and its alloys are the biomaterials most frequently used in medical engineering, especially as parts of orthopedic and dental implants. The surfaces of titanium and its alloys are usually modified to improve their biocompatibility and bioactivity, for example, in connection with the deposition of hydroxyapatite coatings. The objective of the present research was to elaborate the technology of electrophoretic deposition...
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Prediction of metal deformation due to line heating; an alternative method of mechanical bending, based on artificial neural network approach
PublikacjaLine heating is one of the alternative methods of forming metals and this kind of forming uses the heating torch as a source of heat input. During the process, many parameters are considered like the size of the substrate, thickness, cooling method, source power intensity, the travel speed of the power source, the sequence of heating, and so on. It is important to analyze the factors affecting the...
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Comparison of Properties of the Hybrid and Bilayer MWCNTs—Hydroxyapatite Coatings on Ti Alloy
PublikacjaCarbon nanotubes are proposed for reinforcement of the hydroxyapatite coatings to improve their adhesion, resistance to mechanical loads, biocompatibility, bioactivity, corrosion resistance, and antibacterial protection. So far, research has shown that all these properties are highly susceptible to the composition and microstructure of coatings. The present research is aimed at studies of multi-wall carbon nanotubes in three different...
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High-temperature oxidation of the Crofer 22 H ferritic steel with Mn1.45Co1.45Fe0.1O4 and Mn1.5Co1.5O4 spinel coatings under thermal cycling conditions and its properties
PublikacjaThe aim of the presented study was to deposit protective-conducting Mn1.45Co1.45Fe0.1O4 and Mn1.5Co1.5O4 spinel coatings on the Crofer 22 H ferritic steel by means of electrophoresis and to evaluate their physicochemical properties after high-temperature oxidation under thermal cycling conditions. When the Crofer 22 H steel – whether uncoated or coated with the two spinels – was oxidized in 48-h cycles involving a temperature of...
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Light-improved glucose sensing on ordered Au-Ti heterostructure
PublikacjaNon-enzymatic electrochemical platforms sensitive towards glucose presence have attracted a worldwide attention during last decades. We report on influence of solar light onto response of gold-titanium heterostructures prepared via controllable approach. The material based on Au nanoparticles orderly distributed over the structured titanium foil was obtained by electrochemical anodization followed by chemical etching, magnetron...
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Fabrication of Durable Ordered Ta2O5 Nanotube Arrays Decorated with Bi2S3 Quantum Dots
PublikacjaOne of the most important challenges in the fabrication of ordered tantalum pentaoxide (Ta2O5) nanotube arrays (NTs) via the electrochemical method is the formation of nanotubes that adhere well to the Ta substrate. In this paper, we propose a new protocol that allows tight-fitting Ta2O5 nanotubes to be obtained through the anodic oxidation of tantalum foil. Moreover, to enhance their activity in the photocatalytic reaction, in...
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Two-step mechanism of J-domain action in driving Hsp70 function
PublikacjaJ-domain proteins (JDPs), obligatory Hsp70 cochaperones, play critical roles in protein homeostasis. They promote key allosteric transitions that stabilize Hsp70 interaction with substrate polypeptides upon hydrolysis of its bound ATP. Although a recent crystal structure revealed the physical mode of interaction between a J-domain and an Hsp70, the structural and dynamic consequences of J-domain action once bound and how Hsp70s...
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Shielded HMSIW-based frequency-tunable self-quadruplexing antenna using different solid/liquid dielectrics
PublikacjaThis article proposes a frequency-tunable self-quadruplexing antenna based on a shielded half-mode substrate integrated waveguide (S-HMSIW). In order to reduce the size of the HMSIW cavity resonator and to obtain quad-band characteristics, a modied E-shaped slot is engraved on the top of the metal. The experimental validation is carried out after analyzing the data using a circuit model. Flexibility of each resonant frequency is...
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Laser-Induced Graphitization of Polydopamine on Titania Nanotubes
PublikacjaSince the discovery of laser-induced graphite/graphene, there has been a notable surge of scientific interest in advancing diverse methodologies for their synthesis and applications. This study focuses on the utilization of a pulsed Nd:YAG laser to achieve graphitization of polydopamine (PDA) deposited on the surface of titania nanotubes. The partial graphitization is corroborated through Raman and XPS spectroscopies and supported...
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Wideband High-Gain Low-Profile Series-Fed Antenna Integrated with Optimized Metamaterials for 5G millimeter Wave Applications
PublikacjaThis paper presents a series-fed four-dipole antenna with a broad bandwidth, high gain, and compact size for 5G millimeter wave (mm-wave) applications. The single dipole antenna provides a maximum gain of 6.2 dBi within its operational bandwidth, which ranges from 25.2 to 32.8 GHz. The proposed approach to enhance both gain and bandwidth involves a series-fed antenna design. It comprises four dipoles with varying lengths, and a...
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Overview of Metamaterials-Integrated Antennas for Beam Manipulation Applications: The Two Decades of Progress
PublikacjaMetamaterials (MMs) are synthetic composite structures with superior properties not found in naturally occurring materials. MMs have gained massive attention over the last two decades because of their extraordinary properties, such as negative permittivity and permeability. These materials enable many applications in communication subsystems, especially in the field of antenna design, to enhance gain, bandwidth, and efficiency,...
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Compact, Order Extensible and Wide-Stopband Bandpass Filter Based on SIW Cavity with Rectangular Ring Slot
PublikacjaThis article introduces novel architectures of bandpass filters (BPFs) using a substrate integrated waveguide (SIW) cavity with a rectangular ring slot (RRS) for compact size, extensible order, and broad stopband responses. Two bandpass filters, which demonstrate a second-and a fourth-order Chebyshev response, respectively, are realized by employing identical cavities with RRS, without increasing the physical size of the circuit....
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Evaluation of electrosynthesized reduced graphene oxide–Ni/Fe/Co-based (oxy)hydroxide catalysts towards the oxygen evolution reaction
PublikacjaIn this work, the specific role of the addition of graphene oxide (GO) to state-of-the-art nickel–iron (NiFe) and cobalt–nickel–iron (CoNiFe) mixed oxides/hydroxides towards the oxygen evolution reaction (OER) is investigated. Morphology, structure, and OER catalytic activity of the catalysts with and without GO were studied. The catalysts were fabricated via a two-step electrodeposition. The first step included the deposition...
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Multifunctional catalyst-assisted sustainable reformation of lignocellulosic biomass into environmentally friendly biofuel and value-added chemicals
PublikacjaRapid urbanization is increasing the world's energy demand, making it necessary to develop alternative energy sources. These growing energy needs can be met by the efficient energy conversion of biomass, which can be done by various means. The use of effective catalysts to transform different types of biomasses will be a paradigm change on the road to the worldwide goal of economic sustainability and environmental protection. The...
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The Effect of Cobalt Incorporation into Nickel–Iron Oxide/(oxy)hydroxide Catalyst on Electrocatalytic Performance Toward Oxygen Evolution Reaction
PublikacjaThis work presents a study on the influence of the addition of cobalt into state-of-the-art nickel–iron (NiFe) mixed oxides/hydroxides/(oxy)hydroxides on their structural and morphological properties, and oxygen evolution reaction (OER) catalytic activity. A one-step electrodeposition process is performed without any additives to fabricate NiFe and x cobalt-doped nickel/iron (xCoNiFe) layer-double-hydroxide catalysts directly on...
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Highly Miniaturized Self-Diplexed U-Shaped Slot Antenna Based on Shielded QMSIW
PublikacjaThis article presents an efficient yet simple design approach to highly miniaturized cavity-backed self-diplexing antenna (SDA) with high-isolation. The structure employs a shielded quarter-mode substrate integrated waveguide (QMSIW). Two U-shaped slots are engraved on the top conducting plane, which realize two frequency bands and significant size reduction. The slots are excited by two independent 50Ω orthogonal feed-lines to...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 1, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 1, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 60mm), a0/W = 0.6
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 40mm), a0/W = 0.5
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture SEM investigation (plate thicnkness 30mm), a0/W = 0.6
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture SEM investigation (plate thicnkness 30mm), a0/W = 0.5
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 30mm), a0/W = 0.6
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 30mm), a0/W = 0.5
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - Charpy impact test reslut in vary tempetatures
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 40mm), a0/W = 0.6
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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EH36 steel for shipbuilding - tensile test record
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 3, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 3, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 5, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 5, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 2, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 2, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 50mm), a0/W = 0.6
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 4, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 4, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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EH36 steel for shipbuilding - fracture documentation for CTOD test (plate thicnkness 50mm), a0/W = 0.5
Dane BadawczeThe basic method of ductility designation of structural steels is the Charpy impact test. The test consists of a single strike of the specimen using a Charpy pendulum. Its result is the value of work necessary to break a specimen at a test temperature. Despite its many advantages, such as its short implementation time and low costs, it has its disadvantages,...
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Values and problems analysis – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 1, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 1, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Gdańsk-Lower City (Dolne Miasto) district...
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Values and problems analysis – Lower Sopot (Dolny Sopot) district case study, study proposal no 6, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 6, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Lower Sopot (Dolny Sopot) district in the context...
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Values and problems analysis – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 3, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 3, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Gdańsk-Lower City (Dolne Miasto) district...
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Values and problems analysis – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 2, March 2021
Dane BadawczeThe data presents results of work within the studies of the development possibilities of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 2, from March 2021. The goal of the research process was to present the values and problems analysis of the area located in Gdańsk-Lower City (Dolne Miasto) district...
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Protection of Earthing Reactor Connected to the Star Point of a High Voltage Shunt Reactor
PublikacjaThe article presents the problem of protection of earthing reactors connected to the star point of shunt reactors in high voltage lines, with particular regard to the detection of internal faults. Model analyses for an actual system commissioned in 2015, which is intended to be provided with earthing reactors, are included.
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Non-matrix reference materials-the challenges in the preparation of standard gas mixtures
PublikacjaIn the last few years particularly great pressure is exerted on quality control and assurance of analytical measurement results. An invaluable role in this process is played by reference materials. The paper presents the characteristics of basic types of reference materials, with particular attention to gaseous reference materials.
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Colloidal transport of lipid digesta in human and porcine small intestinal mucus
PublikacjaSmall intestinal mucus transport of food-derived particulates has not been extensively studied, despite mucus being a barrier nutrients need to cross before absorption. We used complex dispersions of digesta obtained from simulated, dynamic gastrointestinal digestion of yogurt to examine the penetrability of human and porcine mucus to the particles formed of lipolysis products. Quantitative, time-lapse confocal microscopy revealed...
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Effect of Different Structure Type Traffic On Railway Line Capacity
PublikacjaThe article points to methods of analyzing railway traffic conditions based on two parameters: capacity and delay of trains. The impact of the differentiated railway type structure on the capacity of the railway line was presented. Particular attention has been paid to the assessment of commonly used simplifications in analyzes.
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Mechanical and thermo-mechanical properties of natural rubber composites filled with submicron- and nano-sized silica particles and prepared using glycolysate as a plasticizer
PublikacjaThe main aim of this work was to examine the selected mechanical and thermo-mechanical properties of natural rubber/silica composites prepared using glycolysate as a plasticizer. Prepared composites contained different amounts of submicron- (10, 15, 20 or 25 pphr) or nano-particles (0.5, 0.75, 1.0 or 1.25 pphr). The tensile properties, tear resistance, hardness, abrasion resistance and resilience of prepared materials were determined....
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Trade in value added of countries involved in TTIP: EU-USA comparison
PublikacjaThe aim of this paper is to present key facts concerning trade in the value added of those countries participating in the Transatlantic Trade and Investment Partnership (TTIP). In particular, we describe how involvement in global production networks (GPN) varies across EU countries with respect to the United States.
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Przemysłowa produkcja aminokwasów
PublikacjaProdukcję aminokwasów na skalę przemysłową uruchomiono na początku XX wieku. Obecnie w skali światowej wytwarza się ich prawie 2 mln ton rocznie. Początkowo aminokwasy otrzymywano z hydrolizatów białkowych. Obecnie na drodze syntezy chemicznej otrzymuje się glicynę i DL-metioninę. L-Tryptofan i kwas L-asparaginowy wytwarza się za pomocą enzymów bakteryjnych z prostych substratów. Najpopularniejszą metodą produkcji aminokwasów jest...
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Microwave-assisted boration of potato starch
PublikacjaZiarnistą skrobię ziemniaczaną boranowano za pomocą kwasu borowego i dziesięciowodnego tetraboranu sodu (boraksu) w reakcji wspomaganej mikrofalami. Określono wpływ stosunku substratów oraz czasu trwania i mocy naświetlania na stopień estryfikacji (DE) produktów. Maksymalna wartość DE w próbkach skrobi boranowanej kwasem wyniosła 0,27, a boranowanej boraksem 0,18. Ustalono, że chociaż zmodyfikowana skrobia, o strukturze estrów...
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On the Limiting Distribution of Lempel-Ziv’78 Redundancy for Memoryless Sources
PublikacjaWe study the Lempel-Ziv'78 algorithm and show that its (normalized) redundancy rate tends to a Gaussian distribution for memoryless sources. We accomplish it by extending findings from our 1995 paper, in particular, by presenting a new simplified proof of the central limit theorem (CLT) for the number of phrases in the LZ'78 algorithm. We first analyze the asymptotic behavior of the total path length in the associated digital search...
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Multi-stage magnetic-fluid seals for operating in water - life test procedure, test stand and research results. Part II Results of life tests of multi-stage magnetic - fluid seal operating in water
PublikacjaThe edge criteria for magnetic-fluid seals durability research were described in previous article [24] and now the tests results are presented. The tests were made with three magnetic fluids using various magnets quantity in magnetic assemblies. If values obtained in the repeated test deviated by more than 10 % from results of the first test an additional control test was made for final characteristics. The characteristics are:...
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Chemical composition of lipids isolated from selected organs and tissues of the raccoon dog (Nyctereutes procyonoides)
PublikacjaOur paper presents a qualitative analysis of particular lipid classes (phospholipids, triacylglycerols, cholesterol, free fatty acids) isolated from the tissues of raccoon dogs harvested in northeastern Poland. In all examined tissues (except for the liver) the dominant group of lipids were triacylglycerols. The amounts of lipids representing the other classes depended on the kind of tissue from which the fat was isolated. The...
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Multi-objective weather routing of sailing vessels
PublikacjaThe paper presents a multi-objective deterministic method of weather routing for sailing vessels. Depending on a particular purpose of sailboat weather routing, the presented method makes it possible to customize the criteria and constraints so as to fit a particular user’s needs. Apart from a typical shortest time criterion, safety and comfort can also be taken into account. Additionally, the method supports dynamic weather data:...
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Towards Open Research Data in the Economics Discipline
PublikacjaNowadays, Open Research Data, as one of the three pillars of Open Science (along with Open Access and Open Scholarly Communication), is gaining enormous attention from different academic and commercial environments. A wide range of scientific disciplines represent and produce different types of data and at the same time, gather different issues and problems in terms of sharing and dissemination research output. This chapter aims...